Cytotoxic T-cell clone against rectal carcinoma induced by stimulation of a patient's peripheral blood mononuclear cells with autologous cultured tumor cells

International Journal of Cancer

Volumn 71, Issue 3, 1997, Pages 325-332

  Jacob, Lutz ^a   Somasundaram, Rajasekharan ^a   Smith, William ^b   Monos, Dimitrios ^c   Basak, Saroj ^a   Marincola, Francesco ^d   Pereira, Sarita ^a   Herlyn, Dorothee ^a  

^a WISTAR INSTITUTE   (United States)

^b Riddle Memorial Hospital   (United States)

^c HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; HLA ANTIGEN;

ADULT; ARTICLE; CASE REPORT; CYTOTOXIC T LYMPHOCYTE; EPSTEIN BARR VIRUS; FEMALE; HLA MATCHING; HUMAN; HUMAN CELL; HUMAN TISSUE; MOLECULAR CLONING; MONONUCLEAR CELL; PRIORITY JOURNAL; RECTUM CARCINOMA; VIRUS TRANSFORMATION;

EID: 0031009349     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(sici)1097-0215(19970502)71:3<325::aid-ijc3>3.0.co;2-%23     Document Type: Article

References (40)

1. Cox, A.L., SKIPPER, J., CHEN, Y., HENDERSON, R.A., DARROW, T.L., SHABANOWITZ, J., ENGELHARD, V.H., HUNT, D.F. and SINGLUFF, C.L., JR., , Identification of a peptide recognized by five melanoma-specific human cytotoxic T-cell lines. Science. 264, 716-719 (1994).
2. CSIBA, A., WHITWELL, H.L. and MOORE, M., Distribution of histocompatibility and leukocyte differentiation antigens in normal human colon and in benign and malignant colonie neoplasms. Brit. J. Cancer, 50, 699-709 (1984).
3. lck in T-cells infiltrating human renal cell carcinoma. Cancer Res., 53, 5613-5616 (1993).
4. FLEISCHER, B., SCHREZENMEIER, H. and WAGNER, H., Function of the CD4 and CD8 molecules on human cytotoxic T lymphocytes: regulation of T cell triggering. J. Immunol, 136, 1625-1628 (1986).
5. + T cells recognize a peptide correspondes to a common mutation (13Gly ↠ Asp). Int. J. Cancer, 56, 40-45 (1994).
6. 13 ↠ Asp), are cytotoxic towards a carcinoma cell line harbouring the same mutation. Cancer Inmnmol. Immunother., 40, 165-172 (1995).
7. GUERRY, D., ALEXANDER, M.A., HERLYN, M.F., ZEHNGEBOT, L.M., MITCHELL, K.F., ZMUEWSKI, C.M. and LUSK, E.J., HLA-DR histocompatibility leukocyte antigens permit cultured human melanoma cells from early but not advanced disease to stimulate autologous lymphocytes. J. Clin. Invest., 73, 267-271 (1984).
8. + tumor-specific T cell clones derived from human melanomainfiltratine lymphocytes in response to autologous tumor cells in vitro. Europ. J. Immunol., 24, 1966-1973 (1994).
9. + cytotoxic T cells by sensitization with allogeneic melanomas bearing shared or cross-reactive HLA-A. Cell. Immunol., 139, 411-125 (1992).
10. HERLYN, D., HERLYN, M., Ross, A.H., ERNST, C., ATKINSON, B. and KOPROWSKI, H., Efficient selection of human tumor growth-inhibiting monoclonal antibodies. J. Immunol. Meth., 73, 157-167 (1984).
11. HERLYN, M., STEPLEWSKI, Z., HERLYN, D. and KOPROWSKI, H., Colorectal carcinoma-specific antigen: detection by means of monoclonal antibodies. Proc. Nat. Acad. Sci. (Wash.), 76, 1438-1442 (1979).
12. HOM, S.S., ROSENBERG, S.A. and TOPALIAN, S.L., Specific immune recognition of autologous tumor by lymphocytes infiltrating colon carcinomas: analysis by cytokine secretion. Cancer Immunol. Inimunoflier., 36, 1-8 (1993).
13. ITOH, K., SALMERON, M.A., MORITA, T., SEITO, D., MANSFIELD, P.F., Ross, M.I., BALCH, C.M. and AUGUSTUS, L.B., Distribution of autologous tumor-specific cytotoxic T lymphocytes in human metastatie melanoma. Int. J. Cancer, 52, 52-59 (1992).
14. KAWAKAMI, Y., ELIYAHU, S., JENNINGS, C., SAKAGUCHI, K., KANG, X., SOUTHWOOD, S., ROBBINS, P.E., SETTE, A., APPELLA, E. and ROSENBERG, S.A., Recognition of multiple epitopes in the human melanoma antigen gp 100 by tumor-infiltratins T lymphocytes associated with in vivo tumor regression. J. Immunol., 154, 3961-3968 (1995).
15. KAWAKAMI, Y. and ROBBINS, P., Genes coding for tumor antigens recognized by T lymphocytes. In: V.T. De Vita, S. Hellman and S.A. Rosenberg (eds.). Biologic Therapv of Cancer (2nd ed.), pp. 53-64. J.B. Lippincott, Philadelphia (1995).
16. KAWAKAMI, Y., ROSENBERG, S.A. and LOTZE, M.T., Interleukin-4 promotes the growth of tumor-infiltrating lymphocytes cytoioxic for human autologous melanoma. J. Exp. Med., 168, 2183-2191 (1988).
17. KHARK.EVITCH, D.D., SEITO, D., BALCH, G.C., MAEDA, T., BALCH, C.M. and ITOH, K., Characterization of autologous tumor-specific T-helper 2 cells in tumor-infiltrating lymphocytes from a patient with metastatic melanoma. Int. J. Cancer, 58, 317-323 (1994).
18. + HLA-class I-restricted cytotoxic T cell clones with long-term assay and pretreatment of targets with interteron-γ. Cancer Immunol. Immunother., 37, 187-194 (1993).
19. LIU, S.Q., SHIRAIWA, H., KAWAI, K., HAYASHI, H., AKAZA, H., KIM, B.S., OKI, A., NISHIDA, M., KUBO, T., HASHIZAKI, K., SAIJO, K. and OHNO, T., Tumor-specific autolosous cytotoxic T lymphocytes from tissue sections. Nature (Med.) 2, I283 (1996).
20. LOEFFLER, C.M., SMYTH, M.J., LONGO, D.L., KOPP, W.C., HARVEY, L.K., TRIBBLE, H.R., TASE, J.E., URBA, W.J., LEONARD, A.S., YOUNG, H.A. and OCHOA, A.C., Immunoregulation in cancer-bearing hosts: down-regulation of cone expression and cytotoxic function in CD8 T cells. J. Inimnnol., 149, 949-956 (1992).
21. MlZOGUCHl, H., O'SHEA, J.J., LONGO, D.L., LOEFFLER, C.M., McVlCAR, D.W. and OCHOA, A.C., Alterations in signal transduction molecules in T lymphocytes from tumor-bearing mice. Science, 258, 1795-1798 (1992).
22. + cytotoxic T cell lines against melanoma. Cancer Immunol. Immunother:, 39, 172-178 (1994).
23. MOSMANN, T.R., CHERWINSKI, H., BOND, M.W., GIEDLIN, M.A. and COFFMAN, R.L., Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J. Immunol., 136, 2348-2357 (1986).
24. MULDER, W.M.C., STUKART, M.J., ROOS, M., VAN LIER, R.A.W., WAGSTAFF, J., SCHEPKR, R.J. and BLOEMENA, E., Culture of tumour-infiltrating lymphocytes from melanoma and colon carcinoma: removal of tumour cells does not affect tumour-specificity. Cancer Immunol. Immunother., 41, 293-301 (1995).
25. NAKAGOMI, H., PETERSSON, M., MAGNUSSON, I., JUHLIN, C., MATSUDA, M., MELLSTEDT, H., TAUPIN, J.-L., VIVIER, E., ANDERSON, P. and KIESSLING, R., Decreased expression of the signal-transducing ζ chains in tumorinfiltrating T-cells and NK cells of patients with colorectal carcinoma. Cancer Res., 53, 5610-5612 (1993).
26. PADOVAN, E., CASORATI, G., DELLABONA, P., MEYER, S., BROCKHAUS, M. and LANZAVECCHIA, A., Expression of two T cell receptor α chains: dual receptor T cells. Science, 262, 422-425 (1993).
27. PARRONCHI, P., MACCHIA, D., PICCINNI, M.-P., BISWAS, P., SIMONELLI, C., MAGGI, E., RICCI, M., ANSARI, A.A. and ROMAGNANI, S., Allergen- and bacterial antigen-specific T-cell clones established from atopic donors show a different profile of cytokine production. Proc. Nat. Acad. Sci. (Wash.), 88, 4538-4542 (1991).
28. PATEL, B.T., LUTZ, M.B., SCHLAG, P. and SCHIRRMACHER, V., An analysis of autologous T-cell anti-tumour responses in colon-carcinoma patients following active specific immunization (ASI). Int. J. Cancer, 51, 878-885 (1992).
29. RANSOM, J.H., PELLE, B.A., HUBERS, H., KEYNTON, L.M., HANNA, M.G., JR. and POMATO, N., Identification of colon-tumor-associated antigens by T-cell lines derived from tumor-infiltrating lymphocytes and peripheral-blood lymphocytes from patients immunized with an autologous tumor-cell/ bacillus Calmette-Guérin vaccine. Int. J. Cancer, 54, 734-740 (1993).
30. SALVADORI, S., GANSBACHER, B., PIZZIMENTI A.M. and ZIER, K.S., Abnormal signal transduction by T cells of mice with parental tumors is not seen in mice bearing IL-2-secreting tumors. J. Immunol., 153, 5176-5182 (1994).
31. SANGER, F., NICKLER, S. and COULSON, A.R., DNA sequencing with chainterminating inhibitors. Proc. Nat Acad. Sci. (Wash.), 74, 5463-5467 (1977).
32. SOMERS, S.S.S. and GUILLOU, S.J., Isolation and expansion of lymphocytes from gastrointestinal tumour tissue. Surg. Onco., 2, 283-291 (1993).
33. + cytotoxic T cells can lyse targets via class I molecules and can be blocked by monoclonal antibody against T4 molecules. J. Immunol., 133, 1705-1709 (1984).
34. TENTORI, L., LEONETTI, C., LOZUPONE, F. and BONMASSAR, E., Antitumor and antimetastatic effects of dacarbazine combined with cyclophosphamide and interleukin-2 in Lewis lung carcinoma (3LL). Cancer Immunol. Immunother., 41, 375-383 (1995).
35. TOYONAGA, B., YOSHIKAI, Y., VADASZ, V., CHIN, B. and MAK, T.W., Organization and sequences of the diversity, joining, and constant region genes of the human T-cell receptor βchain. Proc. Nat. Acad. Sci. (Wash.), 82, 8624-8628 (1985).
36. TRAVIS, J., Do tumor-altered cells depress immune responses? Science, 258, 1732-1733 (1992).
37. TSANG, K.Y., ZAREMBA, S., NIERODA, C.A., ZHU, M.Z., HAMILTON, J.M. and SCHLOM, J., Generation of human cytotoxic T cells specific for human carcinoembryonic antigen epitopes from patients immunized with recombinant vaccinia-CEA vaccine. J. Nat. Cancer Inst., 87, 982-990 (1995).
38. VAN DER BRUGGEN, P., TRAVERSARI, C., CHOMEZ, P., LURQUIN, C., DE PLAEN, E., VAN DEN EYNDE, B., KNLUTH, A. and BOON, T., A gene encoding an antigen recosnized by cytolytic T lymphocytes on a human melanoma. Science, 254, 1643-1647 (1991).
39. + T-cell clones established from autolosous mixed lymphocyte-tumor-cell culture (MLTC). Int. J. Cancer, 51, 962-967 (1992).
40. YANG, S.Y., MORISHIMA, Y. COLLINS, N.H., ALTON, T., POLLACK, M.S., YUNIS, E.J. and DUPONT, B., Comparison of one-dimensional IEF patterns for seroloeically detectable HLA-A and B allotypes. Immunogenetics, 19, 217-231 (1984).