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Volumn 47, Issue 1-2, 1997, Pages 311-321

Differential regional effects of long-term L-DOPA treatment on preproenkephalin and preprotachykinin gene expression in the striatum of 6-hydroxydopamine-lesioned rat

Author keywords

Dopamine; L DOPA treatment; mRNA expression; Neostriatum; Neuropeptide

Indexed keywords

ANTIPARKINSON AGENT; BRAIN PROTEIN; ENKEPHALIN; LEVODOPA; MESSENGER RNA; OXIDOPAMINE; PREPROENKEPHALIN; PREPROTACHYKININ; SUBSTANCE P;

EID: 0031009082     PISSN: 0169328X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0169-328X(97)00068-5     Document Type: Article
Times cited : (26)

References (45)
  • 1
    • 0025078156 scopus 로고
    • MK-801 Effects of L-DOPA on extracellular dopamine in striatum of normal and 6-hydroxydopamine-treated rats
    • Abercrombie, D.E., Bonatz, A.E. and Zigmond, M.J., MK-801 Effects of L-DOPA on extracellular dopamine in striatum of normal and 6-hydroxydopamine-treated rats, Brain Res., 525 (1990) 36-44.
    • (1990) Brain Res. , vol.525 , pp. 36-44
    • Abercrombie, D.E.1    Bonatz, A.E.2    Zigmond, M.J.3
  • 2
    • 0028984349 scopus 로고
    • L-DOPA is converted to dopamine in serotonergic fibers of the striatum of the rat: A double-labeling immunofluorescence study
    • Aria, R., Karasawa, N., Geffard, M. and Naghatsu, I., L-DOPA is converted to dopamine in serotonergic fibers of the striatum of the rat: a double-labeling immunofluorescence study, Neurosci. Lett., 195 (1995) 195-198.
    • (1995) Neurosci. Lett. , vol.195 , pp. 195-198
    • Aria, R.1    Karasawa, N.2    Geffard, M.3    Naghatsu, I.4
  • 3
    • 0029034350 scopus 로고
    • Rotation and striatal c-fos expression after repeated, daily treatment with selective dopamine receptor agonists and levodopa
    • Asin, K.E., Bednarz, L., Nikkel, A. and Perner, R., Rotation and striatal c-fos expression after repeated, daily treatment with selective dopamine receptor agonists and levodopa, J. Pharm. Exp. Ther., 273 (1995) 1483-1490.
    • (1995) J. Pharm. Exp. Ther. , vol.273 , pp. 1483-1490
    • Asin, K.E.1    Bednarz, L.2    Nikkel, A.3    Perner, R.4
  • 4
    • 0027280869 scopus 로고
    • Transplantation of fetal nigral cells reverses the increase of preproenkephalin mRNA levels in the rat striatum caused by 6-OHDA lesion of the dopaminergic nigrostriatal pathway: A quantitative in situ hybridization study
    • Bal, A., Savasta, M., Chritin, M., Mennicken F., Abrous, D.N., Le Moal, M., Feuerstein, C. and Herman, J.P., Transplantation of fetal nigral cells reverses the increase of preproenkephalin mRNA levels in the rat striatum caused by 6-OHDA lesion of the dopaminergic nigrostriatal pathway: a quantitative in situ hybridization study, Mol. Brain Res., 18 (1993) 221-227.
    • (1993) Mol. Brain Res. , vol.18 , pp. 221-227
    • Bal, A.1    Savasta, M.2    Chritin, M.3    Mennicken, F.4    Abrous, D.N.5    Le Moal, M.6    Feuerstein, C.7    Herman, J.P.8
  • 5
    • 0028914811 scopus 로고
    • Long-term induction of tyrosine hydroxylase expression: Compensatory response to partial degeneration of the dopaminergic nigrostriatal system in the rat brain
    • Blanchard, V., Christin, M., Vyas, S., Savasta, M., Feuerstein, C., Agid, Y., Javoy-Agid, F. and Raisman-Vozari, R., Long-term induction of tyrosine hydroxylase expression: compensatory response to partial degeneration of the dopaminergic nigrostriatal system in the rat brain, J. Neurochem., 64 (1995) 1669-1679.
    • (1995) J. Neurochem. , vol.64 , pp. 1669-1679
    • Blanchard, V.1    Christin, M.2    Vyas, S.3    Savasta, M.4    Feuerstein, C.5    Agid, Y.6    Javoy-Agid, F.7    Raisman-Vozari, R.8
  • 6
    • 0028093394 scopus 로고
    • Prefrontal corticostriatal afferents maintain increased enkephalin gene expression in the dopamine-denervated rat striatum
    • Campbell, K. and Björklund, A., Prefrontal corticostriatal afferents maintain increased enkephalin gene expression in the dopamine-denervated rat striatum, Eur. J. Neurosci., 6 (1994) 1371-1383.
    • (1994) Eur. J. Neurosci. , vol.6 , pp. 1371-1383
    • Campbell, K.1    Björklund, A.2
  • 7
    • 0027489975 scopus 로고
    • Neuropeptide messenger RNA expression in the 6-hydroxydopamine-lesioned rat striatum reinnervated by fetal dopaminergic transplants: Differential effects of the grafts on preproenkephalin, preprotachykinin an, preprodynorphin messenger RNA levels
    • Cenci, M.A., Campbell, K. and Björklund, A., Neuropeptide messenger RNA expression in the 6-hydroxydopamine-lesioned rat striatum reinnervated by fetal dopaminergic transplants: differential effects of the grafts on preproenkephalin, preprotachykinin an, preprodynorphin messenger RNA levels, Neuroscience, 57 (1993) 275-296.
    • (1993) Neuroscience , vol.57 , pp. 275-296
    • Cenci, M.A.1    Campbell, K.2    Björklund, A.3
  • 8
    • 0027189926 scopus 로고
    • Levodopa induction of fos immunoreactivity in rat brain following partial and complete lesions of the substantia nigra
    • Cole, D.G., Growdon, J.H. and Di Figlia, M., Levodopa induction of fos immunoreactivity in rat brain following partial and complete lesions of the substantia nigra, Exp. Neurol., 120 (1993) 223-232.
    • (1993) Exp. Neurol. , vol.120 , pp. 223-232
    • Cole, D.G.1    Growdon, J.H.2    Di Figlia, M.3
  • 9
    • 0028556522 scopus 로고
    • NMDA receptor blockade reverses motor response alterations induced by levodopa
    • Engber, T.M., Papa, S.M., Boldry, R. and Chase, T.N., NMDA receptor blockade reverses motor response alterations induced by levodopa, NeuroReport, 5 (1994) 2586-2588.
    • (1994) NeuroReport , vol.5 , pp. 2586-2588
    • Engber, T.M.1    Papa, S.M.2    Boldry, R.3    Chase, T.N.4
  • 10
    • 0024436486 scopus 로고
    • Continuous and intermittent levodopa differentially affect rotation induced by D-1 and D-2 dopamine agonists
    • Engber, T.M., Susel, Z., Juncos, J.L. and Chase, T.N., Continuous and intermittent levodopa differentially affect rotation induced by D-1 and D-2 dopamine agonists, Eur. J. Parm., 168 (1989) 291-298.
    • (1989) Eur. J. Parm. , vol.168 , pp. 291-298
    • Engber, T.M.1    Susel, Z.2    Juncos, J.L.3    Chase, T.N.4
  • 11
    • 0025619857 scopus 로고
    • Chronic levodopa treatment alters basal and dopamine agonist-stimulated cerebral glucose utilization
    • Engber, T.M., Susel, Z., Kuo, S. and Chase, T.N., Chronic levodopa treatment alters basal and dopamine agonist-stimulated cerebral glucose utilization, J. Neurosci., 10 (1990) 3889-3895.
    • (1990) J. Neurosci. , vol.10 , pp. 3889-3895
    • Engber, T.M.1    Susel, Z.2    Kuo, S.3    Chase, T.N.4
  • 12
    • 0025765058 scopus 로고
    • Levodopa replacement therapy alters enzyme activities in striatum and neuropeptide content in striatal output regions of 6-hydroxydopamine lesioned rats
    • Engber, T.M., Susel, Z., Kuo, S., Gerfen, C.R. and Chase, T.N., Levodopa replacement therapy alters enzyme activities in striatum and neuropeptide content in striatal output regions of 6-hydroxydopamine lesioned rats, Brain Res., 552 (1991) 113-118.
    • (1991) Brain Res. , vol.552 , pp. 113-118
    • Engber, T.M.1    Susel, Z.2    Kuo, S.3    Gerfen, C.R.4    Chase, T.N.5
  • 13
    • 0025572196 scopus 로고
    • D1 and D2 dopamine receptorregulated gene expression of striatonigral and striatopallidal neurons
    • Gerfen, C.R., Engber, T.M., Mahan, L.C., Susel, Z., Chase, T.N., Monsma, Jr., F.J. and Sibley, D.R., D1 and D2 dopamine receptorregulated gene expression of striatonigral and striatopallidal neurons, Science, 250 (1990) 1429-1432.
    • (1990) Science , vol.250 , pp. 1429-1432
    • Gerfen, C.R.1    Engber, T.M.2    Mahan, L.C.3    Susel, Z.4    Chase, T.N.5    Monsma F.J., Jr.6    Sibley, D.R.7
  • 14
    • 0025944714 scopus 로고
    • Dopamine differentially regulates dynorphin, substance P, and enkephalin expression in striatal neurons: In situ hybridization histochemical analysis
    • Gerfen, C.R., Mc Ginty, J.F. and Young, W.S., Dopamine differentially regulates dynorphin, substance P, and enkephalin expression in striatal neurons: in situ hybridization histochemical analysis, J. Neurosci., 11 (1991) 1016-1031.
    • (1991) J. Neurosci. , vol.11 , pp. 1016-1031
    • Gerfen, C.R.1    Mc Ginty, J.F.2    Young, W.S.3
  • 15
    • 0023695433 scopus 로고
    • Distribution of striatonigral and striatopallidal peptidergic neurons in both patch and matrix compartments: An in situ hybridization histochemistry and fluorescent retrograde tracing study
    • Gerfen, C.R. and Young, III, W.S., Distribution of striatonigral and striatopallidal peptidergic neurons in both patch and matrix compartments: an in situ hybridization histochemistry and fluorescent retrograde tracing study, Brain Res., 460 (1988) 161-167.
    • (1988) Brain Res. , vol.460 , pp. 161-167
    • Gerfen, C.R.1    Young W.S. III2
  • 16
    • 0029670503 scopus 로고    scopus 로고
    • Effect of repeated administration of dopamine agonists on striatal neuropeptide mRNA expression in rats with a unilateral nigral 6-hydroxydopamine lesion
    • Granata, R., Wenning, G.K., Jolkkonen, J., Jenner, P. and Marsden, C.D., Effect of repeated administration of dopamine agonists on striatal neuropeptide mRNA expression in rats with a unilateral nigral 6-hydroxydopamine lesion, J. Neural. Transm., 103 (1996) 249-260.
    • (1996) J. Neural. Transm. , vol.103 , pp. 249-260
    • Granata, R.1    Wenning, G.K.2    Jolkkonen, J.3    Jenner, P.4    Marsden, C.D.5
  • 17
    • 0026005169 scopus 로고
    • N-methyl-D-aspartate antagonists in the treatment of Parkinson's disease
    • Greenamyre, J.T. and O'Brien, C.F., N-methyl-D-aspartate antagonists in the treatment of Parkinson's disease, Ach. Neurol., 48 (1991) 977-981
    • (1991) Ach. Neurol. , vol.48 , pp. 977-981
    • Greenamyre, J.T.1    O'Brien, C.F.2
  • 18
    • 0029923030 scopus 로고    scopus 로고
    • Chronic dizocilpine maleate (MK-801) treatment suppresses the effects of nigrostriatal dopamine deafferentation on enkephalin but not substance P expression in the rat striatum
    • Hajji, My. D., Salin, P. and Kerkerian Le Goff, L., Chronic dizocilpine maleate (MK-801) treatment suppresses the effects of nigrostriatal dopamine deafferentation on enkephalin but not substance P expression in the rat striatum, Eur. J. Neurosci., 8 (1996) 917-926.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 917-926
    • Hajji, My.D.1    Salin, P.2    Kerkerian Le Goff, L.3
  • 19
    • 0029056309 scopus 로고
    • Activation of dopamine cell firing by repeated L-DOPA administration-depleted rats: Its potential role in mediating the therapeutic response to L-DOPA treatment
    • Harden, D.G. and Grace, A.A., Activation of dopamine cell firing by repeated L-DOPA administration-depleted rats: its potential role in mediating the therapeutic response to L-DOPA treatment, J. Neurosci., 15 (1995) 6157-6166.
    • (1995) J. Neurosci. , vol.15 , pp. 6157-6166
    • Harden, D.G.1    Grace, A.A.2
  • 20
    • 0019422869 scopus 로고
    • The site of dopamine formation in rat striatum after L-DOPA administration
    • Hefti, F., Melamed, E. and Wurtman, R.J., The site of dopamine formation in rat striatum after L-DOPA administration, J. Pharmacol. Exp. Ther., 217 (1981) 189-197.
    • (1981) J. Pharmacol. Exp. Ther. , vol.217 , pp. 189-197
    • Hefti, F.1    Melamed, E.2    Wurtman, R.J.3
  • 21
  • 22
    • 0021748307 scopus 로고
    • Molecular cloning and sequence determination of rat preproenkephalin cDNA: Sensitive probe for studying transcriptional changes in rat tissues
    • Howels, R.D., Kilpatrick, D.L., Bhatt, R., Monahan, J.J., Poonian, M. and Udenfriend, S., Molecular cloning and sequence determination of rat preproenkephalin cDNA: sensitive probe for studying transcriptional changes in rat tissues, Proc. Natl. Acad. Sci. USA, 81 (1984) 7651-7655.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 7651-7655
    • Howels, R.D.1    Kilpatrick, D.L.2    Bhatt, R.3    Monahan, J.J.4    Poonian, M.5    Udenfriend, S.6
  • 23
    • 0028984579 scopus 로고
    • L-DOPA reverses altered gene expression of substance P but not enkephalin in the caudate-putamen of common marmosets treated with MPTP
    • Jolkkonen, J., Jenner, P. and Marsden, C.D., L-DOPA reverses altered gene expression of substance P but not enkephalin in the caudate-putamen of common marmosets treated with MPTP, Mol. Brain Res., 32 (1995) 297-307.
    • (1995) Mol. Brain Res. , vol.32 , pp. 297-307
    • Jolkkonen, J.1    Jenner, P.2    Marsden, C.D.3
  • 24
    • 0023196035 scopus 로고
    • 2 sites in rat caudate-putamen: Localization to intrinsic neurons and not to neocortical afferents
    • 2 sites in rat caudate-putamen: localization to intrinsic neurons and not to neocortical afferents, Neuroscience, 20 (1987) 773-795.
    • (1987) Neuroscience , vol.20 , pp. 773-795
    • Joyce, J.N.1    Marshall, J.F.2
  • 26
  • 27
    • 0029002052 scopus 로고
    • D1 and D2 dopamine receptor gene expression in the rat striatum: Sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct neuronal populations of the dorsal and ventral striatum
    • Le Moine, C. and Bloch, B., D1 and D2 dopamine receptor gene expression in the rat striatum: sensitive cRNA probes demonstrate prominent segregation of D1 and D2 mRNAs in distinct neuronal populations of the dorsal and ventral striatum, J. Comp. Neurol., 355 (1995) 418-426.
    • (1995) J. Comp. Neurol. , vol.355 , pp. 418-426
    • Le Moine, C.1    Bloch, B.2
  • 29
    • 0017344150 scopus 로고
    • Success and problems of long-term levodopa therapy in Parkinson's disease
    • Marsden, C.D. and Parkes, J.D., Success and problems of long-term levodopa therapy in Parkinson's disease, Lancet, 1 (1977) 345-349.
    • (1977) Lancet , vol.1 , pp. 345-349
    • Marsden, C.D.1    Parkes, J.D.2
  • 30
    • 0027530686 scopus 로고
    • Normalization of striatal proenkephalin and preprotachykinin mRNA expression by fetal substantia nigra grafts
    • Mendez, I.M., Naus, C.C.G., Elisevich, K. and Flumerfelt, B.A., Normalization of striatal proenkephalin and preprotachykinin mRNA expression by fetal substantia nigra grafts, Exp. Neurol., 119 (1993) 1-10.
    • (1993) Exp. Neurol. , vol.119 , pp. 1-10
    • Mendez, I.M.1    Naus, C.C.G.2    Elisevich, K.3    Flumerfelt, B.A.4
  • 31
    • 0027234405 scopus 로고
    • L-DOPA stimulates c-fos expression in dopamine denervated striatum by combined activation of D-1 and D-2 receptors
    • Morelli, M., Cozzolino, A., Pinna, A., Fenu, S., Carta, A. and Di Chiara, G., L-DOPA stimulates c-fos expression in dopamine denervated striatum by combined activation of D-1 and D-2 receptors, Brain Res., 623 (1993) 334-336.
    • (1993) Brain Res. , vol.623 , pp. 334-336
    • Morelli, M.1    Cozzolino, A.2    Pinna, A.3    Fenu, S.4    Carta, A.5    Di Chiara, G.6
  • 32
    • 0028034707 scopus 로고
    • Differential effect of MK 801 and scopolamine on c-fos expression induced by L-dopa in the striatum of 6-hydroxydopamine lesioned rats
    • Morelli, M., Pinna, A., Fenu, S., Carta, A., Cozzolino, A. and Di Chiara, G., Differential effect of MK 801 and scopolamine on c-fos expression induced by L-dopa in the striatum of 6-hydroxydopamine lesioned rats, Synapse, 18 (1994) 288-293.
    • (1994) Synapse , vol.18 , pp. 288-293
    • Morelli, M.1    Pinna, A.2    Fenu, S.3    Carta, A.4    Cozzolino, A.5    Di Chiara, G.6
  • 33
    • 0029871852 scopus 로고    scopus 로고
    • Partial striatal dopamine depletion differentially affects striatal substance P and enkephalin messenger RNA expression
    • Nisenbaum, L.K., Crowley, W.R. and Kitai, S.T., Partial striatal dopamine depletion differentially affects striatal substance P and enkephalin messenger RNA expression, Mol. Brain Res., 37 (1996) 209-216.
    • (1996) Mol. Brain Res. , vol.37 , pp. 209-216
    • Nisenbaum, L.K.1    Crowley, W.R.2    Kitai, S.T.3
  • 34
    • 0023829728 scopus 로고
    • Dopaminergic neurons of the substantia nigra modulate preproenkephalin A gene expression in rat striatal neurons
    • Normand, E., Popovici, T., Onteniente, B., Fellmann, D., PiatierTonneau, D., Auffray, C. and Bloch, B., Dopaminergic neurons of the substantia nigra modulate preproenkephalin A gene expression in rat striatal neurons, Brain Res., 439 (1988) 39-46.
    • (1988) Brain Res. , vol.439 , pp. 39-46
    • Normand, E.1    Popovici, T.2    Onteniente, B.3    Fellmann, D.4    Piatiertonneau, D.5    Auffray, C.6    Bloch, B.7
  • 36
    • 0029739397 scopus 로고    scopus 로고
    • Bilateral 6-hydroxydopamine-induced lesion of the nigrostriatal dopamine pathway reproduces the effects of unilateral lesion on substance P but not on enkephalin expression in rat basal ganglia
    • Salin, P., Hajji, My. D. and Kerkerian Le Goff, L., Bilateral 6-hydroxydopamine-induced lesion of the nigrostriatal dopamine pathway reproduces the effects of unilateral lesion on substance P but not on enkephalin expression in rat basal ganglia, Eur. J. Neurosci., 8 (1996) 1746-1757.
    • (1996) Eur. J. Neurosci. , vol.8 , pp. 1746-1757
    • Salin, P.1    Hajji, My.D.2    Kerkerian Le Goff, L.3
  • 38
    • 0025953869 scopus 로고
    • Striatal c-fos induction by drugs and stress in neonatally dopamine-depleted rats given nigral transplants: Importance of NMDA activation and relevance to sensitization phenomena
    • Snyder-Keller, A.M., Striatal c-fos induction by drugs and stress in neonatally dopamine-depleted rats given nigral transplants: importance of NMDA activation and relevance to sensitization phenomena, Exp. Neurol., 113 (1991) 155-165.
    • (1991) Exp. Neurol. , vol.113 , pp. 155-165
    • Snyder-Keller, A.M.1
  • 39
    • 0029417247 scopus 로고
    • Antiparkinsonian actions of glutamate antagonists -alone and with L-DOPA: A review of evidence and suggestions for possible mechanisms
    • Starr, M.S., Antiparkinsonian actions of glutamate antagonists -alone and with L-DOPA: a review of evidence and suggestions for possible mechanisms, J. Neural. Transm. P-D Sect., 10 (1995) 141-185.
    • (1995) J. Neural. Transm. P-D Sect. , vol.10 , pp. 141-185
    • Starr, M.S.1
  • 40
    • 0026698939 scopus 로고
    • Effects of a unilateral 6-hydroxydopamine lesion and prolonged L-3,4-dihydrophenylalanine treatment on peptidergic systems in rat basal ganglia
    • Taylor, M.D., De Ceballos, M.L., Rose, S., Jenner, P. and Marsden, C.D., Effects of a unilateral 6-hydroxydopamine lesion and prolonged L-3,4-dihydrophenylalanine treatment on peptidergic systems in rat basal ganglia, Eur. J. Pharm., 219 (1992) 183-192.
    • (1992) Eur. J. Pharm. , vol.219 , pp. 183-192
    • Taylor, M.D.1    De Ceballos, M.L.2    Rose, S.3    Jenner, P.4    Marsden, C.D.5
  • 41
    • 0022481329 scopus 로고
    • The effects of L-DOPA on regional cerebral glucose utilization in rats with unilateral lesions of the substantia nigra
    • Trugman, J.M. and Wooten, G.F., The effects of L-DOPA on regional cerebral glucose utilization in rats with unilateral lesions of the substantia nigra, Brain Res., 379 (1986) 264-274.
    • (1986) Brain Res. , vol.379 , pp. 264-274
    • Trugman, J.M.1    Wooten, G.F.2
  • 42
    • 0023405118 scopus 로고
    • Selective D1 and D2 dopamine agonists differentially alter basal ganglia glucose utilization in rats with unilateral 6-hydroxydopamine substantia nigra lesions
    • Trugman, J.M. and Wooten, G.F., Selective D1 and D2 dopamine agonists differentially alter basal ganglia glucose utilization in rats with unilateral 6-hydroxydopamine substantia nigra lesions, J. Neurosci., 7 (1987) 2927-2935.
    • (1987) J. Neurosci. , vol.7 , pp. 2927-2935
    • Trugman, J.M.1    Wooten, G.F.2
  • 43
    • 0025290906 scopus 로고
    • Responses of substantia nigra pars reticulata neurons to GABA and SKF 38393 in 6-hydroxydopamine-lesioned rats are differentially affected by continuous and intermittent levodopa administration
    • Weick, B.G., Engber, T.M., Susel, Z., Chase, T.N. and Walters, J.R., Responses of substantia nigra pars reticulata neurons to GABA and SKF 38393 in 6-hydroxydopamine-lesioned rats are differentially affected by continuous and intermittent levodopa administration, Brain Res., 523 (1990) 16-22.
    • (1990) Brain Res. , vol.523 , pp. 16-22
    • Weick, B.G.1    Engber, T.M.2    Susel, Z.3    Chase, T.N.4    Walters, J.R.5
  • 44
    • 0010375035 scopus 로고
    • Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrain
    • Young, III, W.S., Bonner, T.I. and Brann, M.R., Mesencephalic dopamine neurons regulate the expression of neuropeptide mRNAs in the rat forebrain, Proc. Natl. Acad. Sci. USA, 83 (1986) 9827-9831.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 9827-9831
    • Young W.S. III1    Bonner, T.I.2    Brann, M.R.3
  • 45
    • 0028988176 scopus 로고
    • Chronic L-DOPA treatment differentially regulates gene expression of glutamate decarboxylase, preproenkephalin and preprotachykinin in the striatum of 6-hydroxydopamine-lesioned rat
    • Zeng, B.-Y., Jolkkonen, J., Jenner, P. and Marsden, C.D., Chronic L-DOPA treatment differentially regulates gene expression of glutamate decarboxylase, preproenkephalin and preprotachykinin in the striatum of 6-hydroxydopamine-lesioned rat, Neuroscience, 66 (1995) 19-28.
    • (1995) Neuroscience , vol.66 , pp. 19-28
    • Zeng, B.-Y.1    Jolkkonen, J.2    Jenner, P.3    Marsden, C.D.4


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