Neurotoxicity and neuroinvasiveness of prions

Journal of NeuroVirology

Volumn 3, Issue SUPPL. 1, 1997, Pages

  Aguzzi, Adriano ^a   Raeber, Alex ^a   Blättler, Thomas ^a   Flechsig, Eckard ^a   Klein, Michael ^a   Weissmann, Charles ^a   Brandner, Sebastian ^a  

^a UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

Neuroectodermal grafting; Prion diseases; Scrapie pathogenesis; Spongiform encephalopathies

Indexed keywords

PRION PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; BRAIN SPONGIOSIS; CENTRAL NERVOUS SYSTEM INFECTION; CONFERENCE PAPER; MOUSE; NEUROTOXICITY; NONHUMAN; PRION; PRION DISEASE; PRIORITY JOURNAL;

ANIMALS; HUMANS; MICE; MICE, TRANSGENIC; NERVE TISSUE PROTEINS; NERVOUS SYSTEM; NEURONS; PRION DISEASES; PRIONS;

EID: 0031009057     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (5)

1. Brandner S, Isenmann S, Räber A, Fischer M, Sailer A, Kobayashi Y, Marino S, Weissmann C, Aguzzi A. (199Ba). Normal host prion protein required for scrapie neurotoxicity. Nature 379: 339-343.
2. C) required for scrapie spread within the central nervous system. Proc. Natl. Acad. Sci. USA 93: 13148-13151.
3. Büeler H, Aguzzi A, Sailer A, Greiner RA, Autenried P, Aguet M, Weissmann C. (1993). Mice devoid of PrP are resistant to scrapie. Cell 73: 1339-1347.
4. Fischer M, Rülicke T, Räber A, Sailer A, Oesch B, Brandner S, Aguzzi A, Weissmann C. (1996). Prion protein (PrP) with amino terminal deletions restoring susceptibility of PrP knockout mice to scrapie. EMBO J 15: 1255-1264.
5. Sailer A, Büeler H, Fischer M, Aguzzi A, Weissmann C. (1994). No propagation of prions in mice devoid of PrP. Cell 77: 967-968.