Use of primary CNS cultures to investigate HIV neurotropism

Journal of NeuroVirology

Volumn 3, Issue SUPPL. 1, 1997, Pages

  González Scarano, Francisco ^a   Strizki, Julie M ^a   Albright, Andrew ^a   Shieh, Joseph ^a  

^a HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

HIV; Microglia; Neurons; Oligodendrocytes; Viral tropism

Indexed keywords

CENTRAL NERVOUS SYSTEM INFECTION; CONFERENCE PAPER; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS; MICROGLIA; NERVE CELL CULTURE; NEUROTROPISM; NONHUMAN; NORMAL HUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; VIRUS REPLICATION;

ASTROCYTES; CELLS, CULTURED; HIV; HUMANS; MICROGLIA; NEURONS; OLIGODENDROGLIA; TEMPORAL LOBE; VIRUS REPLICATION;

EID: 0031009056     PISSN: 13550284     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (12)

1. Alkhatib G, Combadiere C, Broder CC, Feng Y, Kennedy PE, Murphy PM, Berger EA (1995). CC CKR5: a RANTES, MIP-1a, MIP-1b receptor as a fusion cofactor for macrophage-tropic HIV-1. Science 272: 1955-1958.
2. Albright AV, Strizki J, Harouse JM, Lavi E, O'Connor M, Gonzalez-Scarano F (1996). HIV-1 infection of cultured oligodendrocytes. Virology 317: 211-219.
3. Antonioli IM, Baumberger C, Yerly S, Perrin L (1995). V3 Sequences in primary HIV-1 infection. AIDS 9: 11-17.
4. Bagasra O, Lavi E, Bobroski L, Khalili K, Pestaner JP, Tawadros R, Pomerantz RJ (1996). Cellular reservoirs of HIV-1 in the central nervous system of infected individuals: identification by the combination of in situ polymerase chain reaction and immunohistochemistry. AIDS 10: 573-585.
5. Esiri MM, Morris CS, Millard PR (1991). Fate of oligodendrocytes in HIV-1 infection. AIDS 5: 1081-1088.
6. Glass JD, Wesselingh SL, Seines OA, McArthur JC (1993). Clinical-neuropathological correlation in HIV-associated dementia. Neurology 43: 2230-2237.
7. Llanes C, Collman RG, Hrin R, Kolson DL (1995). Acetylcholinesterase expression in Ntera2 human neuronal cells: a model for developmental expression in the nervous system. J Neurosci Res 42: 791-802.
8. Pleasure SJ, Page C, Lee VM-Y (1992). Pure, post-mitotic, polarized human neurons derived from NTera2 cells provide a system for expressing exogenous proteins in terminally differentiated neurons. J Neuroscience 129: 1802-1815.
9. Power C, McArthur JC, Johnson RT, Griffin DE, Glass JD, Perryman S, Chesebro B (1994). Demented and nondemented patients with AIDS differ in brain-derived human immunodeficiency virus type 1 envelope sequences. J Virology 68: 4643-4649.
10. Sharpless NE, O'Brien WA, Verdin E, Kufta CV, Chen ISY, Dubois-Dalcq M (1992). Human immunodeficiency virus type 1 tropism for brain microglial cells is determined by a region of the env glycoprotein that also controls macrophage tropism. J Virology 66: 2588-2593.
11. Strizki JM, Albright AV, Sheng H, O'Connor M, Perrin L, Gonzalez-Scarano F (1996). Infection of primary human microglia and monocyte-derived macrophages with acute HIV-1 isolates: evidence for differential tropism. J Virology 70: 7654-7662.
12. Younkin DP, Tang C-M, Hardy M, Reddy UR, Shi Q-Y, Pleasure SJ, Lee VM-Y, Pleasure D (1993). Inducible expression of neuronal glutamate receptor channels in NT2 human cell line. PNAS 90: 2174-2178.