Microsatellite instability and loss of heterozygosity in primary breast tumours

Tumor Biology

Volumn 18, Issue 3, 1997, Pages 157-166

  Sourvinos, G ^a   Kiaris, H ^a   Tsikkinis, A ^b   Vassilaros, S ^b,c   Spandidos, D A ^a  

^a UNIVERSITY OF CRETE   (Greece)

^b H Venizelou Hospital   (Greece)

^c Prolipsis Breast Diagnostic Center   (Greece)

Author keywords

BRCA1 region; Breast tumours; Hormone receptors; Loss of heterozygosity; Microsatellite instability; THRA1

Indexed keywords

HORMONE RECEPTOR; MICROSATELLITE DNA;

ARTICLE; BREAST CANCER; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; HETEROZYGOSITY LOSS; HUMAN; HUMAN TISSUE; MICROSATELLITE INSTABILITY; PRIORITY JOURNAL;

EID: 0031008841     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1159/000218026     Document Type: Article

References (35)

1. Black DM: The genetics of breast cancer, Eur J Cancer 1994;30A: 1957-1961.
2. Spandidos DA: Oncogene activation in malignant transformation: A study of H-ras in human breast cancer, Anticancer Res 1987;7:991- 996.
3. Micalc MA, Vischer DW, Gulino Sc, Wolman SR: Chromosomal aneuploidy in proliferative breast disease: Hum Pathol 1994:25:29- 35.
4. Aaltonen LA, Peltomaki P, Leach FS, Sistoncn P, Pylkkancn L, Mcck-lin J-P, Jarvinen H, Powel SM, Jen J, Hamilton SR, Petersen GM, Kinzler KW, Vogelstein B, Dc La Chapelle A: Clues to the pathogenesis of familial colorectal cancer, Science 1993;260:812-816.
5. Ionov Y, Peinado MA, Malkhosyan S, Shibita D, Perucho M: Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis, Nature 1993;363:558-561.
6. Thibodeau SN, Bren G, Schaid D: Microsatellitc instability in cancer of the proximal colon, Science 1993; 260:816-819.
7. Richards RI, Sutherland GR: Simple repeat DNA is not replicated simply, Nature Genet 1994;6:114- 116.
8. Spandidos DA: A unified theory for the development of cancer, Biosci Rep 1986;6:691-708.
9. Sato T, Tanigami A, Yamakawa K, Akiyama F, Kasumi F, Sakamoto G, Nakamura Y: Allelotype of breast cancer; cumulative allele losses promote tumor progression in primary breast cancer, Cancer Res 1990;50: 7184-7189.
10. Kiaris H, Jones AS, Spandidos DA, Vaughan ED, Field JK: Loss of heterozygosity on chromosome 8 in squamous cell carcinomas of the head and neck, Int J Oncol 1994;5: 1243-1248.
11. Godwin AK, Vandervcer L, Schultz DC, Lynch HT: A common region on chromosome 17 in both sporadic and familial epithelial ovarian tumors distal to BRCAL Am J Hum Genet 1993;55:666-677.
12. Mori T, Aoki T, Matsubara T, lida F, XiQun D, Nishihira T, Mori S, Nakamura Y: Frequent loss of heterozygosity in the region including BRCAl on chromosome 17q in squamous cell carcinomas of the esophagus, Cancer Res 1994;54: 1638-1640.
13. Kiaris H, Spanakis N, Ergazaki M, Sourvinos G, Spandidos DA: Loss of heterozygosity at 9p and 17q in human laryngeal tumours, Cancer Lett 1995;97:129-134.
14. Fong KM, Kida Y, Zimmerman PV, Ikenaga M, Smith PT: Loss of heterozygosity frequently affects chromosome 17q in non-small cell lung cancer, Cancer Res 1995,55:4268-4272.
15. 7q in human prostate cancer, Cancer Res 1995:55:1002- 1005.
16. Miki Y, Swcnscn J, Shattuck-Eidcns K, Futreal PA, Harshman K, Tavti-gian K, et al: A strong candidate for the breast and ovarian cancer susceptibility gene BRCAl, Science 1994;266:66-71.
17. Anderson LE, Friedman L, Os-borne-Lawrence S, Weissenbach J, Bowcock A, King MC: High-dcnsity map of the BRCAl region of the chromosome 17q 12-21, Genomics 1993;17:618-623.
18. Futreal PA, Soderkvst P, Marks JR, Iglchart JD, Cochran C, Barrett JC, Wiseman RW: Detection of frequent allelic loss on proximal chromosome 17q in sporadic breast carcinoma using microsatellite length polymorphisms, Cancer Res 1992; 52:2624-2627.
19. Weinberg RA: Tumor suppressor genes, Science 1991:254:1138-1146.
20. Neuhausen SL, Marshall CJ: Loss of heterozygosity in familial tumors from three BRCA /-linked kindreds, Cancer Res 1994;54:6069-6072.
21. Cropp CS, Chámpeme M-H, Lide-reau R, Callahan R: Indentification of three regions on chromosome 17q in primary human breast carcinomas which arc frequently deleted, Cancer Res 1993;53:5617-5619.
22. Saito H, Inazawa J, Saito S, Kasumi F, Koi S, Sagae S, Kudo R, Saito J, Noda K, Nakamura Y: Detailed deletion mapping of chromosome 17q in ovarian and breast cancers: 2-cM region on 17q21.3 often and commonly deleted in tumors, Cancer Res 1993;53:3382-3385.
23. Radford DM, Keri LF, Phillips NJ, Ritter JH, Stcinbrucck T, Holt MS, Donis-Keller H: Allelotypingof ductal carcinoma in situ of the breast: Deletion of loci on 8p, 13q, 16q, 17p and 17q.CancerRes 1995:55:3399- 3405.
24. Radford DM, Phillips NJ, Keri LF, Ritter JH, Holt MS, Donis-Keller H: Allelic loss and the progression of the breast cancer, Cancer Res 1995: 55:5180-5182.
25. Patel U, Grundfest-Broniatowski S, Gupta M, Banerjee S: Microsatellite instability at five chromosomes in primary breast tumors, Oncogene 1994:9:3695-3700.
26. Yec CJ, Roodi N, Verrier CS, Pari FF: Microsatcllite instability and loss of heterozygosity in breast cancer, Cancer Res 1994:54:1641-1644.
27. Field JK, Kiaris H, Howard P, Vaughan ED, Spandidos DA, Jones AS: Microsatellite instability in squamous cell carcinoma of the head and neck, Br J Cancer 1995;71: 1065-1069.
28. Kiaris H, Spandidos DA, Jones AS, Vaughan ED, Field JF: Mutations, expression and genomic instability of the H-ras proto-oncogene in squamous cell carcinomas of the head and neck, Br J Cancer 1995:72:123- 128.
29. Baker BS, Smith DA: The effects of mutagen-sensitive mutants of Drosophila melanogaster in non-muta-genized cells, Genetics 1979;92: 833-849.
30. Shibata D, Pcinado MA, Ionov Y, Malkosyan S, Pcrucho M: Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation, Nature Genet 1994: 6:273-281.
31. Nicolaides NC, Papadopoulos N, Liu B, Wei Y, Certer KC, Ruben SM, Rosen CA, Hascltine WA, Flcischmann RD, Fraser CM, Adams MD, Venter JC, Dunlop MG, Hamilton SR, Peterson GM, De La Chapcllc A, Vogelstein B, Kinzlcr KW: Mutations of two PMS homo-logues in hereditary nonpolyposis colon cancer, Nature 1994:371:75-80.
32. Parsons R, Li G-M, Longlcy M, Mo-drich P, Liu B, Berk T, Hamilton SR, Kinzlcr KW, Vogclstein B: Mismatch repair deficiency in pheno-typically normal human cells, Science’ 1995:268:738-740.
33. Ito I, Yoshimoto M, Iwase T, Wata-nabc S, Katagiri T, Harada Y, Kasumi F, Yasuda S, Mitonii T, Emi M, Nakamura Y: Association of genetic alterations on chromosome 17 and loss of hormone receptors in breast cancer, Br J Cancer 1995:71:438-441.
34. Cornclissc CJ, Kuipers-Dijkshoon N, van Vlict M, Hermans J, Devilec P: Fractional allelic imbalances in human breast cancer increases with tctraploid zation and chromosome loss, Int J Cancer 1992;50:544-548.
35. Gonzalez-Zulucta M, Ruppcrt JM, Tokini K, Tsai YC, Spruck CH, Miyao N, Nichols PW, Hermann GG, Horn T, Steven K, Summer-hayes IC, Sidransky D, Jones PA: Microsatcllite instability in bladder cancer, Cancer Res 1993;53:5620- 5623.