-
1
-
-
0342347785
-
-
Japan Kokai Tokkyo Koho, 1993, 5-239009
-
Morrissey, M. M. Japan Kokai Tokkyo Koho, 1993, 5-239009.
-
-
-
Morrissey, M.M.1
-
2
-
-
0002134667
-
-
Verlag Helvetica Chimica Acta: Basel
-
Testa, B; Kyburz, E; Fuhrer, W; Giger, R., Ed. Perspectives in Medicinal Chemistry; Verlag Helvetica Chimica Acta: Basel, 1993; p 27.
-
(1993)
Perspectives in Medicinal Chemistry
, pp. 27
-
-
Testa, B.1
Kyburz, E.2
Fuhrer, W.3
Giger, R.4
-
3
-
-
0027495004
-
-
Ku, T. W.; Ali, F. E.; Barton, L. S.; Bean, J. W.; Bondinell, W. E.; Burgess, J. L.; Callahan, J. F.; Calvo, R. R.; Chen, L.; Eggleston, D. S.; Gleason, J. G.; Huffman, W. F.; Hwang, S. M.; Jakas, D. R.; Karash, C. B.; Keenan, P. M.; Kopple, K. D.; Miller, W. H.; Newlander, K. A.; Nichols, A.; Parker, M. F.; Peishoff, C. E.; Samanen, J. M.; Uzinskas, I.; Venslavsky, J. W., J. Am. Chem. Soc., 1993, 115, 8861.
-
(1993)
J. Am. Chem. Soc.
, vol.115
, pp. 8861
-
-
Ku, T.W.1
Ali, F.E.2
Barton, L.S.3
Bean, J.W.4
Bondinell, W.E.5
Burgess, J.L.6
Callahan, J.F.7
Calvo, R.R.8
Chen, L.9
Eggleston, D.S.10
Gleason, J.G.11
Huffman, W.F.12
Hwang, S.M.13
Jakas, D.R.14
Karash, C.B.15
Keenan, P.M.16
Kopple, K.D.17
Miller, W.H.18
Newlander, K.A.19
Nichols, A.20
Parker, M.F.21
Peishoff, C.E.22
Samanen, J.M.23
Uzinskas, I.24
Venslavsky, J.W.25
more..
-
4
-
-
13344277274
-
-
Moore, W. M.; Webber, R. K.; Fok, K. F.; Jerome, G. M.; Connor, J. R.; Manning, P. T.; Wyatt P. S.; Misko, T. P.; Tjoeng, F. S.; Currie, M. G., J. Med. Chem., 1996, 39, 669.
-
(1996)
J. Med. Chem.
, vol.39
, pp. 669
-
-
Moore, W.M.1
Webber, R.K.2
Fok, K.F.3
Jerome, G.M.4
Connor, J.R.5
Manning, P.T.6
Wyatt, P.S.7
Misko, T.P.8
Tjoeng, F.S.9
Currie, M.G.10
-
5
-
-
0028997861
-
-
Senokuchi, K.; Nakai, H.; Nakayama, Y.; Odagaki, Y.; Sakaki, K.; Kato, M.; Maruyama, T.; Miyazaki, T.; Ito, H.; Kamiyasu, K.; Kim, S.; Kawamura, M.; Hamanaka, N., J. Med. Chem., 1995, 38, 2521.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 2521
-
-
Senokuchi, K.1
Nakai, H.2
Nakayama, Y.3
Odagaki, Y.4
Sakaki, K.5
Kato, M.6
Maruyama, T.7
Miyazaki, T.8
Ito, H.9
Kamiyasu, K.10
Kim, S.11
Kawamura, M.12
Hamanaka, N.13
-
6
-
-
0028862823
-
-
Senokuchi, K.; Nakai, H.; Nakayama, Y.; Odagaki, Y.; Sakaki, K.; Kato, M.; Maruyama, T.; Miyazaki, T.; Ito, H.; Kamiyasu, K.; Kim, S.; Kawamura, M.; Hamanaka, N., J. Med. Chem., 1995, 38, 4508.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 4508
-
-
Senokuchi, K.1
Nakai, H.2
Nakayama, Y.3
Odagaki, Y.4
Sakaki, K.5
Kato, M.6
Maruyama, T.7
Miyazaki, T.8
Ito, H.9
Kamiyasu, K.10
Kim, S.11
Kawamura, M.12
Hamanaka, N.13
-
7
-
-
0029194080
-
-
(a) Kishikawa, K.; Nakao, S.; Matsumoto, S.; Kondo, K.; Hamanaka, N., Adv. in Prostaglandin, Thromboxane, and Leukotriene Research, 1995, 23, 279.
-
(1995)
Adv. in Prostaglandin, Thromboxane, and Leukotriene Research
, vol.23
, pp. 279
-
-
Kishikawa, K.1
Nakao, S.2
Matsumoto, S.3
Kondo, K.4
Hamanaka, N.5
-
8
-
-
0342782839
-
-
note
-
4 antagonists based on the results obtained in 1 and 2.
-
-
-
-
9
-
-
0042597428
-
-
(a) Nii, Y.; Okano, K.; Kobayashi, S.; Ohno, M., Tetrahedron Lett., 1979, 27, 2517.
-
(1979)
Tetrahedron Lett.
, vol.27
, pp. 2517
-
-
Nii, Y.1
Okano, K.2
Kobayashi, S.3
Ohno, M.4
-
10
-
-
0342347782
-
-
note
-
(b) A single isomer was obtained. As far as its stereochemistry (syn or anti) is concerned, exact structural determination using X-ray crystallographic analysis is in progress in our laboratory.
-
-
-
-
11
-
-
0343652998
-
-
Japan Kokai Tokkyo Koho, 1983, 58-41855
-
Sakurai, Y.; Nakayama, T.; Yaegashi, T.; Nunomura, S.; Okutome, T. Japan Kokai Tokkyo Koho, 1983, 58-41855.
-
-
-
Sakurai, Y.1
Nakayama, T.2
Yaegashi, T.3
Nunomura, S.4
Okutome, T.5
-
12
-
-
0342782835
-
-
note
-
Compounds 45a-c were prepared by the usual procedure. equation presented (1) DCC, pyridine, 25 °C, 24 h; (2) TFA, anisole, 2 h.
-
-
-
-
13
-
-
0028314755
-
-
(a) Wikel, J. H.; Sofia, M. J.; Saussy, Jr., D. L.; Bemis, K. G., Bioorg. Med. Chem. Lett., 1994, 4, 795.
-
(1994)
Bioorg. Med. Chem. Lett.
, vol.4
, pp. 795
-
-
Wikel, J.H.1
Sofia, M.J.2
Saussy D.L., Jr.3
Bemis, K.G.4
-
14
-
-
0028004581
-
-
(b) Daines, R. A.; Chambers, P. A.; Eggleston, D. S.; Foley, J. J.; Griswold, D. E.; Haltiwanger, R. C.; Jakas, D. R.; Kingsbury, W. D.; Martin, L. D.; Pendrak. I.; Schmidt, D. B.; Tzimas, M. N.; Sarau, H. M., J. Med. Chem., 1994, 37, 3327.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 3327
-
-
Daines, R.A.1
Chambers, P.A.2
Eggleston, D.S.3
Foley, J.J.4
Griswold, D.E.5
Haltiwanger, R.C.6
Jakas, D.R.7
Kingsbury, W.D.8
Martin, L.D.9
Pendrak, I.10
Schmidt, D.B.11
Tzimas, M.N.12
Sarau, H.M.13
-
15
-
-
0028960927
-
-
(c) Penning, T. D.; Djuric, S. W.; Miyashiro, J. M.; Yu, S.; Snyder, J. P.; Spangler, D.; Anglin, C. P.; Fretland, D. J.; Kachur, J. F.; Keith, R. H.; Tsai, B. S.; Villani-Price, D.; Walsh, R. E.; Widomski, D. L., J. Med. Chem., 1995, 38, 858.
-
(1995)
J. Med. Chem.
, vol.38
, pp. 858
-
-
Penning, T.D.1
Djuric, S.W.2
Miyashiro, J.M.3
Yu, S.4
Snyder, J.P.5
Spangler, D.6
Anglin, C.P.7
Fretland, D.J.8
Kachur, J.F.9
Keith, R.H.10
Tsai, B.S.11
Villani-Price, D.12
Walsh, R.E.13
Widomski, D.L.14
-
16
-
-
0343217365
-
-
note
-
5,6 for 1 and 2 because they contain a common amidinophenyl function as a potency-and spectrum -determining function.
-
-
-
-
17
-
-
0342782833
-
-
note
-
All of the amidine derivatives and the guanidine derivatives were isolated and evaluated as their methanesulfonates.
-
-
-
|