Global cerebral blood flow during infusion of adenosine in humans: Assessment by magnetic resonance imaging and positron emission tomography

Acta Physiologica Scandinavica

Volumn 160, Issue 2, 1997, Pages 117-122

  Stange K ^a   Greitz, D ^a   Ingvar, M ^a   Hindmarsh, T ^a   Sollevi, A ^a  

^a KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Adenosine; Carbon dioxide reactivity; Cerebral circulation; Human; MRI; PET

Indexed keywords

ADENOSINE;

ADULT; ARTICLE; BRAIN BLOOD FLOW; BRAIN CIRCULATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN EXPERIMENT; HYPERVENTILATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NORMAL HUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; VASODILATATION; VOLUNTEER;

EID: 0031008552     PISSN: 00016772     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-201X.1997.00113.x     Document Type: Article

References (32)

1. Belfrage, M., Sollevi, A., Segerdahl, M., Sjölund K-F. & Hansson P. 1995. Systemic adenosine infusion alleviates spontaneous and stimulus evoked pain in patients with peripheral neuropathic pain. Anesth Analg 81, 713-737.
2. Bergström, M., Boethius, J., Eriksson, L., Greitz, T., Ribbe, T. & Widén, L. 1981. Head fixation device for reproducible position alignment in transmission CT and positron emission tomography. J Comput Assist Tomogr 5, 136-141.
3. Bern, R.M., Rubio, R. & Curnish, R.R. 1974. Effect on cerebral vascular resistance and incorporation into cerebral adenine nucleotides. Circ Res 35, 262-271.
4. 15O-labelled butanol for positron tomography. J Nucl Med 31, 1727-1731.
5. Biaggioni, I., Olafsson, B., Robertson, R.M., Hollister, A.S. & Robertson, D. 1987. Cardiovascular and respiratory effects of adenosine in conscious man. Evidence for chemoreceptor activation. Circ Res 61, 779-786.
6. Bohm, C., Greitz, T., Kingsley, D., Berggren, B.M. & Olsson, L. 1983. Adjustable computerised stereotaxic brain atlas for transmission and emission tomography. Am J Neuroradiol 4, 731-733.
7. Dekaban, A.S. 1978. Changes in brain weights during the span of human life: Relation of brain weights to body heights and body weights. Ann Neuro 4, 345-356.
8. Edlund, A., Sollevi, A. & Linde, B. 1990. Haemodynamic and metabolic effects of infused adenosine in man. Clin Sci 79, 131-138.
9. Edlund, A. & Sollevi, A. 1993. Renal effects of i.v. adenosine infusion in humans. Clin Physiol 13, 361-371.
10. Edlund, A., Conradsson, T.B. & Sollevi, A. 1995. A role for adenosine in coronary vasoregulation in man. Effects of theophylline and enprofylline. Clin Physiol 15, 623-636.
11. Eriksson, L., Ingvar, M., Rosenqvist, G., Ekdahl, T. & Stone-Elander, S. 1995 Characteristics of a new automated blood sampling system for positron emission tomography. IEEE 42, 1007-1011.
12. Evans, A.J., Iwai, F. & Grist, T.A. 1993. MR imaging of blood flow with a phase subtraction technique: in vitro and in vivo validation. Invest Radiol 28, 109-115.
13. Forrester, T., Harper, A.M., MacKenzie, E.T. & Thomson, E.M. 1979. Effect of adenosine triphosphate and some derivatives on cerebral blood flow and metabolism. J Physiol 296, 343-355.
14. 1 receptors. JACC 25, 251-257.
15. Greitz, T., Bergström, M., Boethius, J., Kingsley, D. & Ribbe, T. 1980. Head fixation system for integration of radiodiagnostic and therapeutic procedures. Neuroradiology 19, 1-11.
16. Greitz, T., Bohm, C., Holte, S. & Eriksson, L. 1991. A computerized brain atlas: construction, anatomical content, and some applications. J Comput Assist Tomogr 15, 26-38.
17. Heistad, D.D., Marcus, M.L., Gourley, J.K. & Busija, D.W. 1981. Effect of adenosine and dipyridamole on cerebral blood flow. Am J Physiol 240, H775-780.
18. 15O]-butanol and positron emission tomography. J Cereb Blood Flow Metab 14, 628-638.
19. 15O-labelled butanol via organoborane chemistry. Int J Appl Radiat Iso 36, 853-855.
20. Kety, S.S. & Schmidt, C.F. 1948. The effects of altered arterial tensions of carbon dioxide and oxygen on cerebral blood flow and cerebral oxygen consumption of normal young men. J Clin Invest 27, 484-492.
21. Koeppe, R., Holden, J. & Ip, W. 1985. Performance of parameter estimation techniques for the quantitation of local cerebral blood flow by dynamic positron computed tomography. J Cereb Blood Flow Metabol 5, 224-234.
22. Maximillian, A.V., Prohovnik, I. & Risberg, J. 1980. Cerebral hemodynamic response to mental activation in normo- and hypercapnia. Stroke 11, 342-347.
23. Nayler, G.G., Firmin, D.N. & Longmore, D.B. 1986. Blood flow imaging by cine magnetic resonance. J Comput Assist Tomog 10, 715.
24. Pelc, L.R., Pelc, N.J. & Rayhil, S.C 1992. Arterial and venous blood flow: noninvasive quantification with MR imaging. Radiology 185, 808-812.
25. 2 and cerebral hemodynamics. Am J Physiol 206, 25-35.
26. 2 tension and cerebral vascular reactivity during the induction of acute hypertension and hypotension in the awake human. J Neurosurg Anesthesiol 2, 2.
27. Segerdahl, M., Ekblom, A. & Sollevi, A. 1994. The influence of adenosine, ketamine, and morphine on experimentally induced ischemic pain in healthy volunteers. Anesth Analg 79, 787-91.
28. Sollevi, A., Ericson, K., Eriksson, L, Lindqvist, C., Lagerkranser, M. & Stone-Elander, S. 1987. Effect of adenosine on human cerebral blood flow as determined by positron emission tomography. J Cereb Blood Flow Metabol 7, 673-678.
29. Sylvén, C., Beermann, B., Jonzon, B. & Brandt, R. 1986. Angina pectoris-like pain provoked by intravenous adenosine in healthy volunteers. Br Med J, 293.
30. Ukena, D., Olsson, R.A. & Daly, J.W. 1987. Definition of subclasses of adenosine receptors associated with adenylate cyclase: interaction of adenosine analogs with inhibitory A1 receptors and stimulatory A2 receptors. Can J Physiol & Pharmacol 65, 365-376.
31. Wahl, M. & Kuschinsky, W. 1976. The dilatatory action of adenosine on pial arteries of cats and its inhibition by theophylline. Pflügers Arch 362, 55-59.
32. Young, W.L., Prohovnik, I., Ornstein, E., Ostapkowich, N. & Matteo, R.S. 1991. Cerebral blood flow reactivity to changes in carbon dioxide calculated using end-tidal vs. arterial tensions. J Cereb Blood Flow Metab 11, 1031-1035.