Sertoli cells in culture and mRNA differential display provide a sensitive early warning assay system to detect changes induced by xenobiotics

Journal of Andrology

Volumn 18, Issue 3, 1997, Pages 264-273

  Syed, Viqar ^a   Wei, Gu ^a   Hecht, Norman B ^a  

^a TUFTS UNIVERSITY   (United States)

Author keywords

Cadmium; Polychlorinated biphenyls; Spermatogenesis; Testicular toxicants; Testis

Indexed keywords

3,3',4,4' TETRACHLOROBIPHENYL; CADMIUM ACETATE; MESSENGER RNA; POLYCHLORINATED BIPHENYL; POLYCHLORINATED BIPHENYL DERIVATIVE; XENOBIOTIC AGENT;

ANIMAL CELL; ARTICLE; CELL STRUCTURE; CELL VACUOLE; CELL VIABILITY; CONTROLLED STUDY; ENVIRONMENTAL EXPOSURE; GENE EXPRESSION; MALE; MALE INFERTILITY; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SERTOLI CELL; SPERMATOGENESIS;

ACETATES; ANIMALS; CADMIUM; CELLS, CULTURED; GENE EXPRESSION REGULATION; MALE; POLYCHLORINATED BIPHENYLS; POLYMERASE CHAIN REACTION; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; SERTOLI CELLS; TIME FACTORS; TRANSCRIPTION, GENETIC; XENOBIOTICS;

EID: 0031008273     PISSN: 01963635     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (67)

1. Alcivar AA, Hake LE, Millette CF, Trasler JM. Hecht NB. Mitochondrial gene expression in male germ cells of the mouse. Dev Biol 1989;135:263-271.
2. Allen JR, Barsotti DA. Lambrecht LK, Van Miller JP. Reproductive effects of halogenated aromatic hydrocarbons on nonhuman primates. Ann NY Acad Sci 1979;320:419-425.
3. Almiron I, Chemes H. Spermatogenic onset. II. FSH modulates mitotic activity of germ and Sertoli cells in immature rats. Int J Androl 1988;11:235-246.
4. Aoki A, Hoffer AP. Reexamination of the lesions in rat caused by cadmium. Biol Reprod 1978;18:57-59.
5. Barsotti DA, Mailer RJ, Allen JR. Reproductive dysfunction in rhesus monkeys exposed to low levels of polychlorinated biphenyls (Aroclor 1248). Food Cosmet Toxicol 1976;14:99-103.
6. Bergh, ARJ. The acute vascular effects of cadmium in the testis do not require the presence of Leydig cells. Toxicology 1990;63:183-186.
7. Biessman A. Accumulation of polychlorinated biphenyls in steroidogenic tissue of gonads and adrenals in Japanese quail. Arch Environ Contam Toxicol 1981;10:653-662.
8. Cameron E, Foster CL. Observations on the histological effects of sublethal doses of cadmium chloride in the rabbit. I. The effect on the testis. J Anat 1963;97:269-280.
9. Chapin RE. Morphologic evaluation of seminiferous epithelium of the testis. In: Lamb JC IV, Foster PMD, eds. Physiology and Toxicology of Male Reproduction. San Diego: Academic Press; 1988:155-177.
10. Chapin RE, Gray TJ, Phelps JL, Dutton SL. The effect of mono-(2-ethylhexyl)-phthalate on rat Sertoli cell-enriched primary cultures. Toxicol Appl Pharmacol 1988;92:467-479.
11. Chapin RE, Phelps JL, Burka LT, Abou-Donia MB, Heindel JJ. The effects of tri-o-cresyl phosphate and metabolites on rat Sertoli cell function in primary culture. Toxicol Appl Pharmacol 1991;108:194-204.
12. Chapin RE, Fail PA, George JD, Grizzle TB. Heindel JJ, Harry GJ, Collins BJ, Teague J. The reproductive and neural toxicities of acrylamide and three analogues in Swiss mice, evaluated using the continuous breeding protocol. Fundam Appl Toxicol 1995;27:9-24.
13. Clough SR, Michael JW, Payne AH, Brown CD, Brabec MJ. Primary rat Sertoli and interstitial cells exhibit a differential response to cadmium. Cell Biol Toxicol 1990;6:63-79.
14. Coffey D. Androgen action and sex accessory tissues. In: Knobil E, Neill JD, eds. The Physiology of Reproduction. New York: Raven Press; 1988:1081-1089.
15. Colborn T. Pesticides - how research has succeeded and failed to translate science into policy: endocrinological effects on wildlife. Environ Health Perspect 1995;103:81-85.
16. Colborn T, Vom Saal FS, Soto AM. Developmental effects of endocrine-disrupting chemicals. Environ Health Perspect 1993;01:378-384.
17. Cooke PS, Zhao YD, Hansen LG. Neonatal polychlorinated biphenyl treatment increases adult testis size and sperm production in the rat. Toxicol Appl Pharmacol 1996;136:112-117.
18. Espevik T, Lamvik MK, Sunde A, Eik-Nes KB. Effects of cadmium on survival and morphology of cultured rat Sertoli cells. J Reprod Fertil 1982;65:489-495.
19. Fassett DW. Estrogenic and antiestrogenic actions of PCBs in female rats: in vitro and in vivo studies. Reprod Toxicol 1975;7:237-342.
20. Fleischer M, Sarofim AF, Fassett DW, Hammond P, Shackleite HT, Nisbet KT, Epstein S. Environmental impact of cadmium: a review by the panel on hazardous trace substances. Environ Health Perspect 1974;7:253-323.
21. Foster PMD. The Sertoli cell. In: Scialli AR, Clegg ED, eds. Reversibility in Testicular Toxicity Assessment. Boca Raton, Florida: CRC Press; 1992:57-86.
22. Freeman H, Sangalang G. A study of the effects of methylmercury, cadmium arsenic, selenium and a PCB (Aroclor 1254) on adrenal and lesticular steroidogenesis in vitro in the Gray seal (Halichoerus grypus). Arch Environ Contain Toxicol 1977;5:369-374.
23. Friberg L, Piscator M, Nordberg GF, Kjellstrom T. Cadmium in the environment. Cleveland, Ohio: CRC press; 1974.
24. Fuller GB, Hobson WC. Effect of PCBs on reproduction in mammals. In: Waid JS, ed. PCBs and Environment. Boca Raton, Florida: CRC Press; 1987:101-125.
25. Galdieri M, Ziparo E, Polombi F, Russo MA, Stefanini M. Pure Sertoli cell cultures: a new model for the study of somatic-germ cell interactions. J Androl 1981;5:249-259.
26. Gary TJB. Applications of in vitro systems in male reproductive toxicology. In: Lamb JC, Foster PMD, eds. Physiology and Toxicology of Male Reproduction. San Diego: Academic Press; 1988:225-256.
27. George CJ, George WJ. Environmental health. In: Cockerham LG, Shane BS, eds. Basic Environmental Toxicology. Ann Arbor, Michigan: CRS Press; 1990:427-439.
28. Goyer RA. Toxic effects of metals. In: Klaasen CD, Amdur MO, Doull J, eds. Casarelt and Doull's Toxicology. New York: Macmillan; 1986:582-635.
29. Gray LG Jr, Ostby J, Marshall R, Andrews J. Reproductive and thyroid effects of low-level polychlorinated biphenyl (Aroclor 1254) exposure. Fundam Appl Toxicol 1993;20:288-294.
30. Griswold MD, Solari A, Tung PS, Fritz IB. Stimulation by follicle-stimulating hormone of DNA synthesis and of meiosis in cultured Sertoli cells prepared from testes of immature rat. Mol Cell Endocrinol 1977;7:151-165.
31. Hausler A, Hodel C. Ultrastructure alteration induced by two different antispermatogenic agents in the seminiferous epithelium of rat testes. Arch Toxicol 1979;2:387-392.
32. Heindel JJ, Chapin RE, George J, Gulati DK, Fail PA, Barnes LH, Yang RS. Assessment of the reproductive toxicity of a complex mixture of 25 ground water contaminants in mice and rats. Fundam Appl Toxicol 1995;25:9-19.
33. Janecki A, Jakubowiak A, Steinberger A. Effect of cadmium chloride on transepithelial electric resistance of Sertoli cell monolayers in two compartment cultures. A new model for toxicological investigations of the blood testis barrier in vitro. Toxicol Appl Pharmacol 1992;112:51-57.
34. Jansen HT, Cooke PS, Porcelli J, Liu TC, Hausen LG. Estrogenic and antiestrogenic actions of PCBs in the female rat: in vitro and in vivo studies. Reprod Toxicol 1993;7:237-242.
35. Kelce WR, Ewing LL. Male reproductive toxicology. Biomed Environ Sci 1991;4:35-47.
36. Kerr JB, De Kretser DM. Techniques for detecting and evaluating abnormalities in testicular functions. In: Vouk VB, Sheehan PJ, eds. Methods for Assessing the Effects of Chemicals on Reproductive Functions. Chichester: John Wiley and Sons; 1983:247-262.
37. Kihlstrom JE, Olsson M, Jensen AA. Johansson A, Ahlbom J, Bergman A. Effects of PCB on the reproduction of the mink (Mustela vison). Ambio 1992;21:263-278.
38. Kubiak T, Harris H, Smith L, Schwartz T, Stalling D. Trick J, Soleo L, Docherty D, Erdman T. Microcontaminants and reproductive impairment of the Forster's Tern on Green Bay Lake Michigan. Arch Environ Contam Toxicol 1989;18:706-712.
39. Lamb JC. Fundamentals of male reproductive toxicity testing. In: Lamb JC, Foster PMD, eds. Physiology and Toxicology of Male Reproduction. San Diego: Academic Press; 1988:137-153.
40. Laskey JW, Rehnberg GL, Laws SC, Hein JF. Reproductive effects of low doses of cadmium chloride in adult male rats. Toxicol Appl Pharmacol 1984;73:250-255.
41. LeMagueresse B, Jégou B. In vitro effects of germ cells on the secretory activities of Sertoli cells recovered from rats of different ages. Endocrinology 1988;122:1672-1680.
42. LeMagueresse B, LeGac F, Loir M, Jégou B. Stimulation of rat Sertoli cells secretory activity in vitro by germ cells and residual bodies. J Reprod Fertil 1988;77:489-498.
43. Liang PL, Pardee AB. Differential display of eukaryotic messenger RNA by means of polymerase chain reaction. Science 1992;257:967-971.
44. Liang PL, Averboukh K, Pardee AB. Distribution and cloning of eukaryotic mRNAs by means of differential display; refinements and optimization. Nucleic Acids Rec 1993;21:3269-3275.
45. Lucis OJ, Lucis R, Aterman K. Tumorigenesis by cadmium. Oncology 1972;26:53-67.
46. McCoy G, Finlay MF, Rhone A, James K, Cobb GP. Chronic polychlorinated biphenyls exposure on three generations of oldfield mice (Peromyscus polionotus): effects on reproduction, growth and body residues. Arch Environ Contam Toxicol 1995;28:431-435.
47. Moore JA, Hardist JFL, Banas DA, Smith MA. A comparison of liver tumor diagnoses from seven PCB studies in rat. Reg Toxicol Pharmacol 1994;20:362-368.
48. Müller L, Ohnesorge FK. Cadmium-induced alteration of the energy level in isolated hepatocytes. Toxicology 1984;31:297-306.
49. Nisbet ICT. Criteria Document for PCBs. Vol. I. Washington, DC: Massachusetts Audubon Society, Lincoln for Office of Water Planning and Standards, US EPA; 1976.
50. Parizek J. Sterilization of males by cadmium salts. J Reprod Fertil 1960;1:294-309.
51. Parizek J, Zahor Z. Effect of cadmium salts on testicular tissue. Nature 1956;177:1036-1039.
52. Pittenger GL, Gilmond RR, Welsh MJ. The low molecular weight heat-shock protein (hsp27) in rat Sertoli cells: evidence for identity of hsp27 with a germ cell-responsive phosphoprotein. Endocrinology 1992;130:3207-3215.
53. Risebrough RW, Reiche P, Peakall DB, Herman SG, Kirven MN. Polychlorinated biphenyls in the global ecosystem. Nature 1968;220:1098-1102.
54. Safe S. Polychlorinated biphenyls (PCBs): environmental impact, biochemical and toxic responses and implications for risk assessment. Crit Rev Taxicol 1994;24:87-149.
55. Sager DB. Effect of postnatal exposure to polychlorinated biphenyls on adult male reproductive function. Environ Res 1983;31:76-94.
56. Saksena SK, Lau IF. Effects of cadmium chloride on testicular steriodogenesis and fertility of male rats. Endokrinologie 1979;74:6-12.
57. Saksena SK, Dahlgren L, Lau IF, Chang MC. Reproductive and endocrinological features of male rats after treatment with cadmium chloride. Biol Reprod 1977;16:609-613.
58. Sanders O, Kirkpatrick RL. Effects of polychlorinated biphenyls (PCBs) on sleeping times, plasma corticosteroids and testicular activity of white-footed mice. Environ Physiol Biochem 1975;5:308-313.
59. Sanders O, Zopp R, Kirkpatrick RL. Effects of PCB ingestion on sleeping times, organ weights, food consumption, serum corticosterone and survival of albino mice. Bull Environ Contam Toxicol 1974;12:394-399.
60. Sinks T, Steele G, Smith AB, Watkins K, Shultz RA. Mortality among workers exposed to polychlorinated biphenyls. Am J Epidemiol 1992;136:389-394.
61. Swain WR. An overview of the scientific basis for concern with polychlorinated biphenyls in the Great Lakes. In: D'Iti FM, Kamrin MA, eds. PCBs: Human and Environmental Hazards. Ann Arbor, Michigan: Butterworth; 1983:11-48.
62. Toebosch AMW, Robertson DM, Trapman J, Klaassen P, de Paus RA, de Jong FH. Effects of FSH and IGF-I on immature rat Sertoli cells: inhibin α and β subunit mRNA levels and inhibin secretion. Mol Cell Endocrinol 1988;55:101-105.
63. Wade JV, Agrawal PR, Poisner AM. Induction of metallothionein in a human trophoblast cell line by cadmium and zinc. Life Sci 1986;39:1361-1366.
64. Wahba ZZ, Waalkes MP. Effect on in vivo low-dose cadmium pretreatment on the in vitro interactions of cadmium with isolated interstitial cells of the rat testis. Fundam Appl Toxicol 1990;15:641-650.
65. Wassermann M, Wassermann D, Cucos S, Miller HJ. World PCBs map: storage and effects in man and his biological environment in the 1970s. Ann NY Acad Sci 1979;320:69-124.
66. Williams J, Foster PMD. The production of lactate and pyruvate as sensitive indices of altered Sertoli cell function in vitro following the addition of various testicular toxicants. Toxicol Appl Pharmacol 1988;94:160-167.
67. Williams J, Foster PMD. The effects of 1,3 dinitrobenzene and mono (2-ethylhexyl) phthalate on hormonally stimulated lactate and pyruvate production by rat Sertoli cell cultures. Toxicol Lett 1989;47:249-255.