Heterogeneity of antigen expression and lectin labeling on microglial cells in the olfactory bulb of adult rats

Neuroscience Research

Volumn 28, Issue 1, 1997, Pages 67-75

  Wu, C H ^a   Chien, H F ^b   Chang, C Y ^a   Ling, E A ^c  

^a TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^b NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Antigen expression; Lectin histochemistry; Microglia; Olfactory bulb

Indexed keywords

CD45 ANTIGEN; COMPLEMENT COMPONENT C3 RECEPTOR; LECTIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MEMBRANE ANTIGEN;

ANIMAL CELL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ARTICLE; CELL ULTRASTRUCTURE; CONTROLLED STUDY; GOLGI COMPLEX; GRANULE CELL; IMMUNOREACTIVITY; MACROPHAGE; MALE; MICROGLIA; NERVE DEGENERATION; NERVE REGENERATION; NONHUMAN; OLFACTORY BULB; OLFACTORY NERVE; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RAT;

ANIMALS; ANTIGENS; ANTIGENS, CD4; ANTIGENS, CD45; HISTOCOMPATIBILITY ANTIGENS CLASS I; HISTOCOMPATIBILITY ANTIGENS CLASS II; HISTOCYTOCHEMISTRY; LECTINS; MACROPHAGES; MALE; MICROGLIA; OLFACTORY BULB; RATS; RATS, WISTAR; RECEPTORS, COMPLEMENT;

EID: 0031007844     PISSN: 01680102     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0168-0102(97)01178-4     Document Type: Article

References (35)

1. Bauer, J., Siminia, T., Wouterlood, F.G. and Dijkstra, C.D. (1994) Phagocytic activity of macrophages and microglial cells during the course of acute and chronic relapsing experimental autoimmune encephalomyelitis. J. Neurosci. Res., 38: 365-375.
2. Caggiano, A.O. and Brunjes, P.C. (1993) Microglia and the developing olfactory bulb. Neuroscience, 52: 717-724.
3. Dijkstra, C.D., Dopp, E.A., Joling, P. and Kraal, G. (1985) The heterogeneity of mononuclear phagocytes in lymphoid organs: Distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3. Immunology, 54: 589-599.
4. Doyle, C. and Strominger, J.L. (1987) Interaction between CD4 and class II MHC molecules mediates cell adhesion. Nature, 330: 256-259.
5. Gehrmann, J., Bonnekoh, P., Miyazawa, T., Hossmann, K.A. and Kreutzberg, G.W. (1992) Immunocytochemical study of an early microglial activation in ischemia. J. Cereb. Blood Flow Metab., 12: 257-269.
6. Graeber, M.B., Streit, W.J. and Kreutzberg, G.W. (1988) Axotomy of the rat facial nerve leads to increased CR3 complement receptor expression by activated microglial cells. J. Neurosci. Res., 21: 18-24.
7. Graeber, M.B., Streit, W.J., Kiefer, R., Schoen, S.W. and Kreutzberg, G.W. (1990) New expression of myelomocytic antigens by microglia and perivascular cells following lethal motor neuron injury. J. Neuroimmunol., 27: 121-132.
8. Hayes, C.E. and Goldstein, I.J. (1974) An α-D-Galactosyl-binding lectin from Bandeiraea simplicifolia seeds. Isolation by affinity chromatography and characterization. J. Biol. Chem. 249, 1904-1914.
9. Hickey, W.F., Vass, K. and Lassmann, H. (1992) Bone marrow derived elements in the central nervous system: an immunohistochemical and ultrastructural survey of rat chimeras. J. Neuropathol. Exp. Neurol., 51: 246-256.
10. Itagaki, S., McGeer, P.L. and Akiyama, H. (1988) Presence of T-cytotoxic suppressor and leucocyte common antigen positive cells in Alzheimer's disease brain tissue. Neurosci. Lett., 91: 259-264.
11. Kaplan, M.S., McNelly, N.A. and Hinds, J.W. (1985) Population dynamics of adult-formed granule neurons of the rat olfactory bulb. J. Comp. Neurol., 239: 117-125.
12. Kaur, C., Yong, E.S. and Ling, E.A. (1993) Studies of activated microglia and macrophages in lumbosacral spinal cord following an intraperitoneal injection of 6-aminonicotinamide into adult rats. Histol. Histopathol., 8: 699-707.
13. Kearney, J.F., Radbruch, A., Liesegang, B. and Rajewsky, K. (1979) A new mouse myeloma cell line that has lost immunoglobulin expression but permits the construction of antibody-secreting hybrid cell lines. J. Immunol., 123: 1548-1550.
14. Kida, S., Steart, P.V., Zhang, E.T. and Weller, R.O. (1993) Perivascular cells act as scavengers in the cerebral perivascular spaces and remain distinct from pericytes, microglia and macrophages. Acta Neuropathol., 85: 646-652.
15. Korol, D.L. and Burnjes, P.C. (1992) Unilateral naris closure and vascular development in the rat olfactory bulb. Neuroscience, 46: 631-641.
16. Lassmann, H., Schmied, M., Vass, K. and Hickey, W.F. (1993) Bone marrow derived elements and resident microglia in brain inflammation. Glia, 7: 19-24.
17. Lawson, L.J., Perry, V.H., Dri, P. and Gordon, S. (1990) Heterogeneity in the distribution and morphology of microglia in the normal adult mouse brain. Neuroscience, 39: 151-170.
18. Lawson, L.J., Perry, V.H. and Gordon, S. (1992) Turnover of resident microglia in the normal adult mouse brain. Neuroscience, 48: 405-415.
19. Ling, E.A., Kaur, C. and Wong, W.C. (1991) Expression of major histocompatibility complex and leucocyte common antigens in amoeboid microglia in postnatal rats. J. Anat., 177: 117-126.
20. Ling, E.A., Kaur, C. and Wong, W.C. (1992) Expression of major histocompatibility complex antigens and CR3 complement receptors in activated microglia following an injection of ricin into the sciatic nerve in rats. Histol. Histopathol., 7: 93-100.
21. Lowe, J., Maclennan, K.A., Powe, D.G., Pound, J.D. and Palmer, J.B. (1989) Microglial cells in human brain have phenotypic characteristics related to possible function as dendritic antigen presenting cells. J. Pathol., 159: 143-149.
22. Mander, T.H. and Morris J.F. (1995) Immunophenotypic evidence for distinct populations of microglia in the rat hypothalamo-neurohypophysial system. Cell Tissue Res., 280: 665-673.
23. McMaster, W.R. and Williams, A.F. (1979) Identification of Ig glycoproteins in rat thymus and purification from rat spleen. Eur. J. Immunol. 9: 426-433.
24. Morioka, T., Baba, T., Black, K.L. and Streit, W.J. (1992a) Immunophenotypic analysis of infiltrating leukocytes and microglia in an experimental rat glioma. Acta Neuropathol., 83: 590-597.
25. Morioka, T., Kalehua, A. N. and Streit, W.J. (1992b) Progressive expression of immunomolecules on microglial cells in rat dorsal hippocampus following transient forebrain ischemia. Acta Neuropathol., (Berlin) 83: 149-157.
26. Perry, V.H., Matyszak, M.K. and Fearn, S. (1993) Altered antigen expression of microglia in the aged rodent CNS. Glia, 7: 60-67.
27. Pingel, J.T. and Thomas, M.L. (1989) Evidence that the leukocyte common antigen is required for antigen-induced T lymphocyte proliferation. Cell, 58: 1055-1065.
28. Robinson, A.P., White, T.M. and Mason, D.W. (1986) Macrophage heterogeneity in the rat as delineated by two monoclonal antibodies MRC OX-41 and MRC OX-42. the latter recognizing complement receptor type 3. Immunology, 57: 239-247.
29. Sunderland, C.A., McMaster, W.R. and Williams, A.F. (1979) Purification with monoclonal antibody of predominant leukocyte-common antigen and glycoprotein from rat thymocytes. Eur. J. Immunol. 9: 155-159.
30. Streit, W.J., Graeber, M.B. and Kreutzberg, G.W. (1989) Expression of Ia antigens on perivascular and microglial cells after sublethal and lethal neuronal injury. Exp. Neurol. 105: 115-126.
31. Vass, K. and Lassmann, H. (1990) Intrathecal application of interferon gamma, progressive appearance of MHC antigens within the rat nervous system. Am. J. Pathol., 137: 790-801.
32. Williams, A.F., Galfre, G. and Milstein, D. (1977) Analysis of cell surfaces by xenogeneic myeloma-hybrid antibodies: differentiation antigens of rat lymphocytes. Cell, 12: 663-673.
33. Wu, C.H., Wen, C.Y., Shieh, J.Y. and Ling, E.A. (1992) A quantitative and morphometric study of the transformation of amoeboid microglia into ramified microglia in the developing corpus callosum in rats. J. Anat., 182: 423-430.
34. Wu, C.H., Wen, C.Y., Shieh, J.Y. and Ling, E.A. (1993) A quantitative study of the differentiation of microglial cells in the developing cerebral cortex in rats. J. Anat., 182: 403-413.
35. Wu, C.H., Wen, C.Y., Shieh, J.Y. and Ling, E.A. (1994) Down-regulation of membrane glycoprotein in amoeboid microglia transforming into ramified microglia in postnatal rat brain. J. Neurocytol., 23: 258-269.