-
1
-
-
0019428416
-
Chronic reserpine treatment alters the sensitivity and membrane potential of the rabbit saphenous artery
-
ABEL, P. W., URQUILLA, P. R., GOTO, K., WESTFALL, D. P., ROBINSON, R. L. AND FLEMING, W. W.: Chronic reserpine treatment alters the sensitivity and membrane potential of the rabbit saphenous artery. J. Pharmacol. Exp. Ther. 217:430-439, 1981.
-
(1981)
J. Pharmacol. Exp. Ther.
, vol.217
, pp. 430-439
-
-
Abel, P.W.1
Urquilla, P.R.2
Goto, K.3
Westfall, D.P.4
Robinson, R.L.5
Fleming, W.W.6
-
2
-
-
0018133542
-
Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal responses by clonidine
-
AGHAJANIAN, G. K.: Tolerance of locus coeruleus neurones to morphine and suppression of withdrawal responses by clonidine. Nature (Lond.) 276: 186-188, 1978.
-
(1978)
Nature (Lond.)
, vol.276
, pp. 186-188
-
-
Aghajanian, G.K.1
-
3
-
-
0027305997
-
Opiates suppress a resting inward current in addition to activating an outward potassium current in locus coeruleus neurons
-
ALREJA, M. AND AGHAJANIAN, G. K.: Opiates suppress a resting inward current in addition to activating an outward potassium current in locus coeruleus neurons. J. Neurosci. 13: 3525-3532, 1993
-
(1993)
J. Neurosci.
, vol.13
, pp. 3525-3532
-
-
Alreja, M.1
Aghajanian, G.K.2
-
4
-
-
0021995621
-
Opiate- And alpha2-adrenoceptor-induced hyperpolarizations of locus ceruleus neurons in brain slices: Reversal by cyclic adenosine 3′:5′-monophosphate analogues
-
ANDRADE, R. AND AGHAJANIAN, G. K.: Opiate- and alpha2-adrenoceptor-induced hyperpolarizations of locus ceruleus neurons in brain slices: Reversal by cyclic adenosine 3′:5′-monophosphate analogues. J. Neurosci. 5: 2359-2364, 1985.
-
(1985)
J. Neurosci.
, vol.5
, pp. 2359-2364
-
-
Andrade, R.1
Aghajanian, G.K.2
-
5
-
-
0020501879
-
Morphine tolerance and dependence in the locus coeruleus: Single cell studies in brain slices
-
ANDRADE, R., VANDERMAELEN, C. P. AND AGHAJANIAN, G. K.: Morphine tolerance and dependence in the locus coeruleus: Single cell studies in brain slices. Eur. J. Pharmacol. 91: 161-169, 1983.
-
(1983)
Eur. J. Pharmacol.
, vol.91
, pp. 161-169
-
-
Andrade, R.1
Vandermaelen, C.P.2
Aghajanian, G.K.3
-
6
-
-
0023838029
-
Neurotransmitters: Past, present, and future directions
-
BLOOM, F. E.: Neurotransmitters: past, present, and future directions. FASEB J. 2: 32-41, 1988.
-
(1988)
FASEB J.
, vol.2
, pp. 32-41
-
-
Bloom, F.E.1
-
7
-
-
85045799288
-
Opioid receptor reserve in normal and morphine-tolerant guinea pig ileum myenteric plexus
-
CHAVKIN, C. AND GOLDSTEIN, A.: Opioid receptor reserve in normal and morphine-tolerant guinea pig ileum myenteric plexus. Proc. Natl. Acad. Sci. U.S.A. 82: 1860-1863, 1984.
-
(1984)
Proc. Natl. Acad. Sci. U.S.A.
, vol.82
, pp. 1860-1863
-
-
Chavkin, C.1
Goldstein, A.2
-
8
-
-
0021339197
-
Actions of γ-aminobutyric acid on neurons of guinea-pig myenteric plexus
-
CHERUBINI, E. AND NORTH, R. A.: Actions of γ-aminobutyric acid on neurons of guinea-pig myenteric plexus. Br. J. Pharmacol. 82: 93-100, 1984.
-
(1984)
Br. J. Pharmacol.
, vol.82
, pp. 93-100
-
-
Cherubini, E.1
North, R.A.2
-
9
-
-
0001485959
-
A general theory of the genesis of drug dependence by induction of receptors
-
COLLIER, H. O. J.: A general theory of the genesis of drug dependence by induction of receptors. Nature 205: 181-182, 1965.
-
(1965)
Nature
, vol.205
, pp. 181-182
-
-
Collier, H.O.J.1
-
10
-
-
0001256847
-
Tolerance, physical dependence and receptors
-
COLLIER, H. O. J.: Tolerance, physical dependence and receptors. Adv. Drug Res. 3: 171, 1966.
-
(1966)
Adv. Drug Res.
, vol.3
, pp. 171
-
-
Collier, H.O.J.1
-
11
-
-
0021051234
-
Electro physiology of opioids
-
DUGGAN, A. W. AND NORTH, R. A.: Electro physiology of opioids. Pharmacol. Rev. 35: 219-281, 1984.
-
(1984)
Pharmacol. Rev.
, vol.35
, pp. 219-281
-
-
Duggan, A.W.1
North, R.A.2
-
12
-
-
0023723042
-
Acute and chronic opiate regulation of adenylate cyclase in brain: Specific effects in locus coeruleus
-
DUMAN, R. S., TALLMAN, I. F. AND NESTLER, E. J.: Acute and chronic opiate regulation of adenylate cyclase in brain: specific effects in locus coeruleus. J. Pharmacol. Exper. Ther. 246: 1033-1039, 1988.
-
(1988)
J. Pharmacol. Exper. Ther.
, vol.246
, pp. 1033-1039
-
-
Duman, R.S.1
Tallman, I.F.2
Nestler, E.J.3
-
13
-
-
0015552450
-
Postjunctional supersensitivity and subsensitivity of excitable tissues to drugs
-
FLEMING, W. W., McPHILLIPS, J. J. AND WESTFALL, D. P.: Postjunctional supersensitivity and subsensitivity of excitable tissues to drugs. Ergeb. Physiol. Biol. Chem. Exp. Pharmakol. 68: 55-119, 1973.
-
(1973)
Ergeb. Physiol. Biol. Chem. Exp. Pharmakol.
, vol.68
, pp. 55-119
-
-
Fleming, W.W.1
McPhillips, J.J.2
Westfall, D.P.3
-
14
-
-
0002443191
-
Cellular mechanisms of opioid tolerance and dependence
-
ed. by L. F. Tseng , Amsterdam, Harwood Academic Publishers
-
FLEMING, W. W. AND TAYLOR, D. A.: Cellular mechanisms of opioid tolerance and dependence. In Pharmacology of Opioid Peptides, ed. by L. F. Tseng , pp. 463-502, Amsterdam, Harwood Academic Publishers, 1995.
-
(1995)
Pharmacology of Opioid Peptides
, pp. 463-502
-
-
Fleming, W.W.1
Taylor, D.A.2
-
15
-
-
0016662910
-
Altered resting membrane potential in the supersensitive vas deferens of the guinea pig
-
FLEMING, W. W. AND WESTFALL, D. P.: Altered resting membrane potential in the supersensitive vas deferens of the guinea pig. J. Pharmacol. Exp. Ther. 192: 381-389, 1975.
-
(1975)
J. Pharmacol. Exp. Ther.
, vol.192
, pp. 381-389
-
-
Fleming, W.W.1
Westfall, D.P.2
-
16
-
-
0000175535
-
Adaptive supersensitivity
-
U. Trendelenburg and N. Weiner, eds. Heidelberg, Springer Verlag
-
FLEMING, W. W. AND WESTFALL, D. P.: Adaptive supersensitivity. In Catecholamines. Handbook of Experimental Pharmacology, Vol 90, U. Trendelenburg and N. Weiner, eds, pp. 509-559. Heidelberg, Springer Verlag, 1988.
-
(1988)
Catecholamines. Handbook of Experimental Pharmacology
, vol.90
, pp. 509-559
-
-
Fleming, W.W.1
Westfall, D.P.2
-
18
-
-
0018398048
-
Involvement of the sodium-potassium pump in the mechanism of postjunctional supersensitivity of the vas deferens of the guinea pig
-
GERTHOFFER, W. T., FEDAN, J. S., WESTFALL, D. P., GOTO, K. AND FLEMING, W. W.: Involvement of the sodium-potassium pump in the mechanism of postjunctional supersensitivity of the vas deferens of the guinea pig. J. Pharmacol. Exp. Ther. 210: 27-36, 1979.
-
(1979)
J. Pharmacol. Exp. Ther.
, vol.210
, pp. 27-36
-
-
Gerthoffer, W.T.1
Fedan, J.S.2
Westfall, D.P.3
Goto, K.4
Fleming, W.W.5
-
19
-
-
0017817663
-
Denervation-induced changes in elect rophysiologic parameters of the smooth muscle of the guinea-pig and rat vas deferens
-
GOTO, K., WESTFALL, D. P. AND FLEMING, W. W.: Denervation-induced changes in elect rophysiologic parameters of the smooth muscle of the guinea-pig and rat vas deferens. J. Pharmacol. Exp. Ther. 204: 325-333, 1978.
-
(1978)
J. Pharmacol. Exp. Ther.
, vol.204
, pp. 325-333
-
-
Goto, K.1
Westfall, D.P.2
Fleming, W.W.3
-
20
-
-
0024849486
-
Identification of morphine- And cyclic AMP-regulated phosphoproteins (MARPPs) in the locus coeruleus and other regions of rat brain: Regulation by acute and chronic morphine
-
GUITART, X. AND NESTLER, E.: Identification of morphine- and cyclic AMP-regulated phosphoproteins (MARPPs) in the locus coeruleus and other regions of rat brain: Regulation by acute and chronic morphine. J. Neurosci. 9: 4371-4387, 1989.
-
(1989)
J. Neurosci.
, vol.9
, pp. 4371-4387
-
-
Guitart, X.1
Nestler, E.2
-
23
-
-
0015985705
-
Two types of neurons in the myenteric plexus of the duodenum in the guinea-pig
-
HIRST, G. D. S., HOLMAN, M. E. AND SPENCE, I.: Two types of neurons in the myenteric plexus of the duodenum in the guinea-pig. J. Physiol. 236: 303-326, 1974.
-
(1974)
J. Physiol.
, vol.236
, pp. 303-326
-
-
Hirst, G.D.S.1
Holman, M.E.2
Spence, I.3
-
24
-
-
0024948637
-
Mechanisms of cellular adaptive sensitivity changes: Applications to opioid tolerance and dependence
-
JOHNSON, S. M. AND FLEMING, W. W.: Mechanisms of cellular adaptive sensitivity changes: Applications to opioid tolerance and dependence. Pharmacol. Rev. 41: 435-88, 1989.
-
(1989)
Pharmacol. Rev.
, vol.41
, pp. 435-488
-
-
Johnson, S.M.1
Fleming, W.W.2
-
25
-
-
0025168606
-
Hyperpolarization of myenteric neurons by opioids does not involve cyclic adenosine-3′,5′-monophosphate
-
JOHNSON, S. M. AND PILLAI, N. P.: Hyperpolarization of myenteric neurons by opioids does not involve cyclic adenosine-3′,5′-monophosphate. Neuroscience 36: 299-304, 1990.
-
(1990)
Neuroscience
, vol.36
, pp. 299-304
-
-
Johnson, S.M.1
Pillai, N.P.2
-
26
-
-
0017804293
-
Sensitivities of the isolated ileal longitudinal smooth muscle-myenteric plexus and hypogastric nerve-vas deferens of the guinea pig after chronic morphine pellet implantation
-
JOHNSON, S. M., WESTFALL, D. P., HOWARD, S. A. AND FLEMING, W. W.: Sensitivities of the isolated ileal longitudinal smooth muscle-myenteric plexus and hypogastric nerve-vas deferens of the guinea pig after chronic morphine pellet implantation. J. Pharmacol. Exp. Ther. 204: 54-66, 1978.
-
(1978)
J. Pharmacol. Exp. Ther.
, vol.204
, pp. 54-66
-
-
Johnson, S.M.1
Westfall, D.P.2
Howard, S.A.3
Fleming, W.W.4
-
27
-
-
0023229387
-
Naloxone-induced depolarization and synaptic activation of myenteric neurons in morphine dependent guinea-pig ileum
-
JOHNSON, S. M., WILLIAMS, J. T., COSTA, M. AND FURNESS, J. B.: Naloxone-induced depolarization and synaptic activation of myenteric neurons in morphine dependent guinea-pig ileum. Neuroscience 21: 595-602, 1987.
-
(1987)
Neuroscience
, vol.21
, pp. 595-602
-
-
Johnson, S.M.1
Williams, J.T.2
Costa, M.3
Furness, J.B.4
-
28
-
-
0026544355
-
Elevated basal firing rates and enhanced responses to 8-Br-cAMP in locus coeruleus neurons in brain slices from opiate-dependent rats
-
KOGAN, J. H., NESTLER, E. J. AND AGHAJANIAN, G. K.: Elevated basal firing rates and enhanced responses to 8-Br-cAMP in locus coeruleus neurons in brain slices from opiate-dependent rats. Eur. J. Pharmacol. 211: 47-53, 1992.
-
(1992)
Eur. J. Pharmacol.
, vol.211
, pp. 47-53
-
-
Kogan, J.H.1
Nestler, E.J.2
Aghajanian, G.K.3
-
29
-
-
0030933915
-
Evidence that tolerance and dependence of guinea pig myenteric neurons to opioids is a function of altered electrogenic sodium-potassium pumping
-
KONG, J-Q., LEEDHAM, J. A., TAYLOR, D. A. AND FLEMING, W. W.: Evidence that tolerance and dependence of guinea pig myenteric neurons to opioids is a function of altered electrogenic sodium-potassium pumping. J. Pharmacol. Exp. Ther. 280: 593-599, 1997.
-
(1997)
J. Pharmacol. Exp. Ther.
, vol.280
, pp. 593-599
-
-
Kong, J.-Q.1
Leedham, J.A.2
Taylor, D.A.3
Fleming, W.W.4
-
30
-
-
0025720139
-
Involvement of mu, delta and kappa receptors in morphine-induced tolerance in the guinea-pig myenteric plexus
-
LEEDHAM. J. A., BENNETT, L. E., TAYLOR, D. A. AND FLEMING, W. W.: Involvement of mu, delta and kappa receptors in morphine-induced tolerance in the guinea-pig myenteric plexus. J. Pharmacol. Exp. Ther. 259: 295-301, 1991.
-
(1991)
J. Pharmacol. Exp. Ther.
, vol.259
, pp. 295-301
-
-
Leedham, J.A.1
Bennett, L.E.2
Taylor, D.A.3
Fleming, W.W.4
-
31
-
-
0024387368
-
The development and reversal of the tolerance to morphine in the longitudinal smooth musclemyenteric plexus preparation of the guinea-pig
-
LEEDHAM, J. A., DOAK, N., TAYLOR, D. A. AND FLEMING, W. W.: The development and reversal of the tolerance to morphine in the longitudinal smooth musclemyenteric plexus preparation of the guinea-pig. Life Sci. 45: 1483-1489, 1989.
-
(1989)
Life Sci.
, vol.45
, pp. 1483-1489
-
-
Leedham, J.A.1
Doak, N.2
Taylor, D.A.3
Fleming, W.W.4
-
32
-
-
0026784229
-
Membrane potential in myenteric neurons associated with tolerance and dependence upon morphine
-
LEEDHAM, J. A., KONG, J.-Q., TAYLOR, D. A., JOHNSON, S. M. AND FLEMING, W. W.: Membrane potential in myenteric neurons associated with tolerance and dependence upon morphine. J. Pharmacol. Exp. Ther. 263: 15-19, 1992.
-
(1992)
J. Pharmacol. Exp. Ther.
, vol.263
, pp. 15-19
-
-
Leedham, J.A.1
Kong, J.-Q.2
Taylor, D.A.3
Johnson, S.M.4
Fleming, W.W.5
-
33
-
-
0030999755
-
Chronic morphine treatment of guinea pigs induces nonspecific sensitivity changes in the nucleus tractus solitarius in vitro
-
MALANGA, C. J., MENG, J., FLEMING, W. W. AND TAYLOR, D. A.: Chronic morphine treatment of guinea pigs induces nonspecific sensitivity changes in the nucleus tractus solitarius in vitro. J. Pharamacol. Exp. Ther. 280: 16-23, 1997.
-
(1997)
J. Pharamacol. Exp. Ther.
, vol.280
, pp. 16-23
-
-
Malanga, C.J.1
Meng, J.2
Fleming, W.W.3
Taylor, D.A.4
-
34
-
-
0023944007
-
The ionic mechanisms underlying opioid actions
-
McFADZEAN, I.: The ionic mechanisms underlying opioid actions. Neuropeptides 11: 173-180, 1988.
-
(1988)
Neuropeptides
, vol.11
, pp. 173-180
-
-
McFadzean, I.1
-
35
-
-
0345166585
-
Chronic treatment with morphine is associated with heterologous tolerance of guinea pig locus ceruleus (LC) neurons
-
MENG, J., FLEMING, W. W. AND TAYLOR, D. A.: Chronic treatment with morphine is associated with heterologous tolerance of guinea pig locus ceruleus (LC) neurons. Soc. Neurosci. Abst. 22: 1162, 1996.
-
(1996)
Soc. Neurosci. Abst.
, vol.22
, pp. 1162
-
-
Meng, J.1
Fleming, W.W.2
Taylor, D.A.3
-
36
-
-
0026645205
-
Molecular mechanisms of drug addiction
-
NESTLER, E. J.: Molecular mechanisms of drug addiction. J. Neurosci. 12: 2439-2450, 1992.
-
(1992)
J. Neurosci.
, vol.12
, pp. 2439-2450
-
-
Nestler, E.J.1
-
37
-
-
0024498255
-
Regulation of G-proteins by chronic morphine in the rat locus coeruleus
-
NESTLER, E. J., ERDOS, J. J., TERWILLIGER, R., DUMAN, R. S. AND TALLMAN, J. F.: Regulation of G-proteins by chronic morphine in the rat locus coeruleus. Brain Res. 476: 230-239, 1989.
-
(1989)
Brain Res.
, vol.476
, pp. 230-239
-
-
Nestler, E.J.1
Erdos, J.J.2
Terwilliger, R.3
Duman, R.S.4
Tallman, J.F.5
-
38
-
-
0023868861
-
Chronic morphine treatment increases cyclic AMP-dependent protein kinase activity in the rat locus coeruleus
-
NESTLER, E. J. AND TALLMAN, J. F.; Chronic morphine treatment increases cyclic AMP-dependent protein kinase activity in the rat locus coeruleus. Mol. Pharmacol. 33: 127-132, 1988.
-
(1988)
Mol. Pharmacol.
, vol.33
, pp. 127-132
-
-
Nestler, E.J.1
Tallman, J.F.2
-
39
-
-
0015828225
-
Intracellular recording from the myenteric plexus of the guinea-pig ileum
-
NISHI, S. AND NORTH, R. A.: Intracellular recording from the myenteric plexus of the guinea-pig ileum. J. Physiol. (Lond.) 231: 471-491, 1973.
-
(1973)
J. Physiol. (Lond.)
, vol.231
, pp. 471-491
-
-
Nishi, S.1
North, R.A.2
-
40
-
-
0020675917
-
Actions and distributions of opioid peptides in peripheral tissues
-
NORTH, R. A. AND EGAN, T. M.: Actions and distributions of opioid peptides in peripheral tissues. Br. Med. Bull. 39: 71-75, 1983.
-
(1983)
Br. Med. Bull.
, vol.39
, pp. 71-75
-
-
North, R.A.1
Egan, T.M.2
-
41
-
-
0017688475
-
The mechanism of action of narcotic analgesics in the guinea-pig ileum
-
NORTH, R. A. AND TONINI, M.: The mechanism of action of narcotic analgesics in the guinea-pig ileum. Br. J. Pharmacol. 61: 541-549, 1977.
-
(1977)
Br. J. Pharmacol.
, vol.61
, pp. 541-549
-
-
North, R.A.1
Tonini, M.2
-
42
-
-
0020616602
-
How do opiates inhibit transmitter release?
-
NORTH, R. A. AND WILLIAMS, J. T.: How do opiates inhibit transmitter release? Trends Neurosci. 6: 337-339, 1983.
-
(1983)
Trends Neurosci.
, vol.6
, pp. 337-339
-
-
North, R.A.1
Williams, J.T.2
-
43
-
-
0026088535
-
The electrophysiological effects of [D-Ala2,NMe-Phe4,Gly5-ol]enkephalin on guinea-pig myenteric neurons
-
PILLAI, N. P. AND JOHNSON, S. M.; The electrophysiological effects of [D-Ala2,NMe-Phe4,Gly5-ol]enkephalin on guinea-pig myenteric neurons. Eur. J. Pharmacol. 192: 227-233, 1991.
-
(1991)
Eur. J. Pharmacol.
, vol.192
, pp. 227-233
-
-
Pillai, N.P.1
Johnson, S.M.2
-
44
-
-
0027443667
-
Characterization of the properties of canine colonie smooth muscle in culture
-
ROGERS, M. J., WARD, S. M., HORNER, M. A., SANDERS, K. M. AND HOROWITZ, B.: Characterization of the properties of canine colonie smooth muscle in culture. Am. J. Physiol. 265: C1433-C1442, 1993.
-
(1993)
Am. J. Physiol.
, vol.265
-
-
Rogers, M.J.1
Ward, S.M.2
Horner, M.A.3
Sanders, K.M.4
Horowitz, B.5
-
45
-
-
0016355903
-
Morphine tolerance and supersensitivity to 5-hydroxytryptamine in the myenteric plexus of the guinea pig
-
SCHULZ, R. AND GOLDSTEIN, A.: Morphine tolerance and supersensitivity to 5-hydroxytryptamine in the myenteric plexus of the guinea pig. Nature 251: 329-331, 1973.
-
(1973)
Nature
, vol.251
, pp. 329-331
-
-
Schulz, R.1
Goldstein, A.2
-
46
-
-
0345171323
-
Mechanisms of transmitter action in the vertebrate central nervous system
-
Bloom, F. E., eds. Bethesda, MD, Am. Physiol. Soc.
-
SIGGINS, G. R. AND GRUOL, D. L.: Mechanisms of transmitter action in the vertebrate central nervous system. Bloom, F. E., eds., In Handbook of physiology, Section 1, The Nervous System, Vol. IV, Intrinsic Regulatory Systems of the Brain. Bethesda, MD, Am. Physiol. Soc., 1-114, 1986.
-
(1986)
Handbook of physiology, Section 1, The Nervous System, Vol. IV, Intrinsic Regulatory Systems of the Brain
, vol.4
, pp. 1-114
-
-
Siggins, G.R.1
Gruol, D.L.2
-
47
-
-
0022344193
-
2-adrenoceptors co-exist on myenteric but not on submucous neurones
-
2-adrenoceptors co-exist on myenteric but not on submucous neurones. Neuroscience 16: 425-430, 1985.
-
(1985)
Neuroscience
, vol.16
, pp. 425-430
-
-
Surprenant, A.1
North, R.A.2
-
48
-
-
0024250999
-
Morphine tolerance and nonspecific subsensitivity of the longitudinal muscle/myenteric plexus preparation of the guinea pig to inhibitory agonists
-
TAYLOR, D. A., LEEDHAM, J. A., DOAK, N. AND FLEMING, W. W.: Morphine tolerance and nonspecific subsensitivity of the longitudinal muscle/myenteric plexus preparation of the guinea pig to inhibitory agonists. Naunyn-Schmiedeberg Arch. Pharmacol. 338: 553-559, 1988.
-
(1988)
Naunyn-Schmiedeberg Arch. Pharmacol.
, vol.338
, pp. 553-559
-
-
Taylor, D.A.1
Leedham, J.A.2
Doak, N.3
Fleming, W.W.4
-
49
-
-
0021715347
-
Opiate receptor interactions on single locus coeruleus neurones
-
WILLIAMS, J. T. AND NORTH, R. A.: Opiate receptor interactions on single locus coeruleus neurones. Mol. Pharmacol. 26: 489-497, 1984.
-
(1984)
Mol. Pharmacol.
, vol.26
, pp. 489-497
-
-
Williams, J.T.1
North, R.A.2
|