Prognosis of radically operated breast carcinoma patients. A retrospective study of 167 consecutive patients with emphasis on histopathological grading, reproducibility and mean nuclear area

APMIS

Volumn 105, Issue 5, 1997, Pages 363-370

  Raabe, N K ^a   Schistad, O ^b   Sauer, T ^b   Bofin, A ^c   Kaaresen, R ^b   Fossaa, S D ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b ULLEVÅL UNIVERSITY HOSPITAL   (Norway)

^c TRONDHEIM UNIVERSITY HOSPITAL   (Norway)

Author keywords

Breast carcinoma; Histopathological grading; Mean nuclear area; Prognosis

Indexed keywords

ADULT; AGED; ARTICLE; BREAST CANCER; FEMALE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MORPHOMETRICS; PRIORITY JOURNAL; PROGNOSIS;

EID: 0031007282     PISSN: 09034641     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1699-0463.1997.tb00582.x     Document Type: Article

References (19)

1. Altman, D. G.: Practical statistics for Medical Research. Chapman and Hall. London pp. 1991, 403-405.
2. Bloom, H. J. G. & Richardson, W. W.: Histological grading and prognosis in breast cancer. Br. J. Cancer 11: 359-377, 1957.
3. Chamberlain, J., Coleman, D. & Ellman, R.: Verification of the cause of death in the trial of early detection of breast cancer. UK Trial of Early Detection of Breast Cancer Group. Br. J. Cancer 64: 1151-1156, 1991.
4. Davey, D. D., Banks, E. R., Jennings, D. & Powell, D. E.: Comparison of nuclear grade and DNA cytometry in breast carcinoma aspirates to histologic grade in excised cancers. Am. J. Clin. Pathol. 99: 708-713, 1993.
5. Early Breast Cancer Trialists' Collaborative Group: Systemic treatment of early breast cancer by hormonal, cytotoxic, or immune therapy. Lancet 339: 1-15, 71-85, 1992.
6. Early Breast Cancer Trialists' Collaborative Group.: Effects of radiotherapy and surgery in early breast cancer. An overview of the randomized trials. N. Engl. J. Med. 333: 1444-1455, 1995.
7. Elston, C. W. & Ellis, I. O.: Pathological prognostic factors in breast cancer. I. The value of histological grade in breast cancer: experience from a large study with long-term follow-up. Histopathology 19: 403-410, 1991.
8. EORTC breast cancer cooperative group: Manual for clinical research in breast cancer. 5th EORTC Breast Cancer Working Conference. Radiotherapy Department, University Hospital, Leuven, Belgium 1991.
9. Fisher, B., Constantino, J., Redmond, C., Poisson, R., Bowman, D., Couture, J., Dimitrov, N. V., Wolmark, N., Wickerham, D. L., Fisher, E. R., Margolese, R., Robidoux, A., Shibata, H., Terz, J., Peterson, A. H. G., Feldman, M. I., Farrar, W., Evans, J., Lickley, H. L. & Keiner, M.: A randomized clinical trial evaluating tamoxifen in the treatment of patients with node-negative breast cancer who have estrogen receptor-positive tumors. N. Engl. J. Med. 320: 479-484, 1989.
10. Gundersen, H. J. G., Bendtsen, T. F., Korbo, L., Marcussen, N., Moller, A., Nielsen, K., Nyengaard, J. R., Pakkenberg, B., Sorensen, F. B., Vesterby, A. & West, M. J.: Some new, simple and efficient stereological methods and their use in pathological research and diagnosis. APMIS 96: 379-394, 1988.
11. Gundersen, S., Boehler, P. J., Hannisdal, E. & Host, H.: Prognostic and therapeutic significance of tumour size and histologic grading in node-negative breast cancer. Tidsskr. Nor. Laegeforen. 116: 222-225, 1996.
12. Henderson, I. C., Hayes, D. F., Parker, L. M., Love, S., Garber, J. E., Recht, A., Breitmeyer, J. B., Harris, J. R. & Canellos, G. P.: Adjuvant systemic therapy for patients with node-negative tumours. Cancer 65: 2132-2147, 1990.
13. Henson, D. E., Ries, L., Freedman, L. S. et al.: Relationship among outcome, stage of disease, and histological grade for 22, 616 cases of breast cancer. The basis for a prognostic index. Cancer 68: 2142-2149, 1991.
14. Maehle, B. O., Skjaerven, R. & Collett, K.: Prognosis in node-negative breast cancer patients: The importance of tumour diameter and mean nuclear area. Eur. J. Surg. Oncol. 14: 21-26, 1988.
15. Norwegian Breast Cancer Group (NBCG): Cancer mammae. Diagnosis and treatment. 4th edition. Oslo, 1994.
16. O'Reilly, S. M., Camplejohn, R. S., Barnes, D. M., Millis, R. R., Rubens, R. D. & Richards, M. A.: Node-negative breast cancer: Prognostic sub-groups defined by tumour size and flow cytometry. J. Clin. Oncol. 8: 2040-2046, 1990.
17. Ottestad, L., Pettersen, E. O., Nesland, J. M., Hannisdal, E., Fossa, S. D. & Tveit, K. M.: Flow cytometric DNA analysis as prognostic factor in human breast carcinoma. Pathol. Res. Pract. 189: 405-410, 1993.
18. Skjoerten, F., Kaaresen, R., Jacobsen, U., Skaane, P. & Amlie, E.: Nuclear morphometry of benign and malignant breast lesions. Eur. J. Surg. Oncol. 17: 350-353, 1991.
19. Veronesi, U., Salvadori, B., Luini, A., Greco, M., Saccozzi, R., del Vecchio, M., Mariani, L., Zurrida, S. & Rilke, F.: Breast conservation is a safe method in patients with small cancer of the breast. Long-term results of three randomized trials on 1973 patients. Eur. J. Cancer. 31A; 10: 1574-1579, 1995.