메뉴 건너뛰기




Volumn 176, Issue 1, 1997, Pages 189-195

Clostridial gas gangrene: Evidence that α and θ toxins differentially modulate the immune response and induce acute tissue necrosis

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CLOSTRIDIUM PERFRINGENS; CONTROLLED STUDY; GAS GANGRENE; HISTOPATHOLOGY; IMMUNOMODULATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; STRAIN DIFFERENCE; TISSUE NECROSIS; TOXIN ANALYSIS;

EID: 0031007249     PISSN: 00221899     EISSN: None     Source Type: Journal    
DOI: 10.1086/514022     Document Type: Article
Times cited : (100)

References (28)
  • 1
    • 0002723116 scopus 로고
    • Clostridium perfringens
    • Smith LDS, ed. Springfield, IL: CC Thomas
    • Smith LDS. Clostridium perfringens. In: Smith LDS, ed. The pathogenic anaerobic bacteria. Springfield, IL: CC Thomas, 1975:115-76.
    • (1975) The Pathogenic Anaerobic Bacteria , pp. 115-176
    • Smith, L.D.S.1
  • 3
    • 0001653358 scopus 로고
    • The histotoxic clostridial infections of man
    • MacLennan JD. The histotoxic clostridial infections of man. Bacteriologic Rev 1962;26:177-276.
    • (1962) Bacteriologic Rev , vol.26 , pp. 177-276
    • MacLennan, J.D.1
  • 4
    • 0017359627 scopus 로고
    • Gas gangrene and related infection: Classification, clinical features and aetiology, management and mortality. A report of 88 cases
    • Darke SG, King AM, Slack WK. Gas gangrene and related infection: classification, clinical features and aetiology, management and mortality. A report of 88 cases. Br J Surg 1977;64:104-12.
    • (1977) Br J Surg , vol.64 , pp. 104-112
    • Darke, S.G.1    King, A.M.2    Slack, W.K.3
  • 5
    • 0343846074 scopus 로고
    • Role of toxins in host-parasite relationships
    • Montie TC, Kadis S, Ajl SJ, eds. London: Academic Press
    • Bullen JJ. Role of toxins in host-parasite relationships. In: Montie TC, Kadis S, Ajl SJ, eds. Microbial toxins. London: Academic Press, 1970: 233-75.
    • (1970) Microbial Toxins , pp. 233-275
    • Bullen, J.J.1
  • 6
    • 0008305409 scopus 로고
    • Type A Clostridium perfringens toxin
    • Kadis S, Montie TC, Ajl SJ, eds. New York: Academic Press
    • Ispolatovskaya MV. Type A Clostridium perfringens toxin. In: Kadis S, Montie TC, Ajl SJ, eds. Microbial toxins. New York: Academic Press, 1972:109-58.
    • (1972) Microbial Toxins , pp. 109-158
    • Ispolatovskaya, M.V.1
  • 7
    • 0023930231 scopus 로고
    • Lethal effects and cardiovascular effects of purified α- and θ-toxins from Clostridium perfringens
    • Stevens DL, Troyer BE, Merrick DT, Mitten JE, Olson RD. Lethal effects and cardiovascular effects of purified α- and θ-toxins from Clostridium perfringens. J Infect Dis 1988;157:272-9.
    • (1988) J Infect Dis , vol.157 , pp. 272-279
    • Stevens, D.L.1    Troyer, B.E.2    Merrick, D.T.3    Mitten, J.E.4    Olson, R.D.5
  • 8
    • 0028786567 scopus 로고
    • Effects of Clostridium perfringens recombinant and crude phospholipase C and θ toxins on rabbit hemodynamic parameters
    • Asmuth DA, Olson RD, Hackett SP, et al. Effects of Clostridium perfringens recombinant and crude phospholipase C and θ toxins on rabbit hemodynamic parameters. J Infect Dis 1995;172:1317-23.
    • (1995) J Infect Dis , vol.172 , pp. 1317-1323
    • Asmuth, D.A.1    Olson, R.D.2    Hackett, S.P.3
  • 9
    • 0018440656 scopus 로고
    • Virulence factors of Clostridium perfringens
    • Smith LDS. Virulence factors of Clostridium perfringens. Rev Infect Dis 1979;1:254-60.
    • (1979) Rev Infect Dis , vol.1 , pp. 254-260
    • Smith, L.D.S.1
  • 10
    • 0015866804 scopus 로고
    • Purification of phospholipase C (alpha-toxin) from Clostridium perfringens
    • Mollby RC, Wadstrom T. Purification of phospholipase C (alpha-toxin) from Clostridium perfringens. Biochim Biophys Acta 1973;321:569-84.
    • (1973) Biochim Biophys Acta , vol.321 , pp. 569-584
    • Mollby, R.C.1    Wadstrom, T.2
  • 11
    • 0025775605 scopus 로고
    • Evidence that Clostridium perfringens theta-toxin induces colloid-osmotic lysis of erythrocytes
    • Harris RW, Sims PJ, Tweten RK. Evidence that Clostridium perfringens theta-toxin induces colloid-osmotic lysis of erythrocytes. Infect Immun 1991;59:2499-501.
    • (1991) Infect Immun , vol.59 , pp. 2499-2501
    • Harris, R.W.1    Sims, P.J.2    Tweten, R.K.3
  • 12
    • 0028945951 scopus 로고
    • Virulence studies on chromosomal α-toxin and θ toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of α-toxin in Clostridium perfringens - Mediated gas gangrene
    • Awad MM, Bryant AE, Stevens DL, Rood JI. Virulence studies on chromosomal α-toxin and θ toxin mutants constructed by allelic exchange provide genetic evidence for the essential role of α-toxin in Clostridium perfringens - mediated gas gangrene. Mol Microbiol 1995;15:191-202.
    • (1995) Mol Microbiol , vol.15 , pp. 191-202
    • Awad, M.M.1    Bryant, A.E.2    Stevens, D.L.3    Rood, J.I.4
  • 13
    • 0028089780 scopus 로고
    • Role of alpha-toxin in Clostridium perfringens infection determined by using recombinants of C. perfringens and Bacillus subtilis
    • Ninomiya M, Matsushita O, Minami J, Sakamoto H, Nakano M, Okabe A. Role of alpha-toxin in Clostridium perfringens infection determined by using recombinants of C. perfringens and Bacillus subtilis. Infect Immun 1994;62:5032-9.
    • (1994) Infect Immun , vol.62 , pp. 5032-5039
    • Ninomiya, M.1    Matsushita, O.2    Minami, J.3    Sakamoto, H.4    Nakano, M.5    Okabe, A.6
  • 14
    • 0023228890 scopus 로고
    • Effects of α and θ toxins from Clostridium perfringens on human polymorphonuclear leukocytes
    • Stevens DL, Mitten J, Henry C. Effects of α and θ toxins from Clostridium perfringens on human polymorphonuclear leukocytes. J Infect Dis 1987; 156:324-33.
    • (1987) J Infect Dis , vol.156 , pp. 324-333
    • Stevens, D.L.1    Mitten, J.2    Henry, C.3
  • 16
    • 0027717232 scopus 로고
    • Clostridium perfringens invasiveness is enhanced by effects of theta toxin upon PMNL structure and function: The roles of leukocytotoxicity and expression of CD11/ CD18 adherence glycoprotein
    • Bryant AE, Bergstrom R, Zimmerman GA, et al. Clostridium perfringens invasiveness is enhanced by effects of theta toxin upon PMNL structure and function: the roles of leukocytotoxicity and expression of CD11/ CD18 adherence glycoprotein. FEMS Immunol Med Microbiol 1993; 7:321-36.
    • (1993) FEMS Immunol Med Microbiol , vol.7 , pp. 321-336
    • Bryant, A.E.1    Bergstrom, R.2    Zimmerman, G.A.3
  • 17
    • 0024573685 scopus 로고
    • The regulation of platelet activating factor synthesis in endothelial cells - The role of calcium and protein kinase C
    • Whatley RE, Zimmerman GA, Stevens DL, Parker CJ, McIntyre TM, Prescott SM. The regulation of platelet activating factor synthesis in endothelial cells - the role of calcium and protein kinase C. J Biol Chem 1989;11:6325-33.
    • (1989) J Biol Chem , vol.11 , pp. 6325-6333
    • Whatley, R.E.1    Zimmerman, G.A.2    Stevens, D.L.3    Parker, C.J.4    McIntyre, T.M.5    Prescott, S.M.6
  • 18
    • 0030031443 scopus 로고    scopus 로고
    • Phospholipase C and perfringolysin O from Clostridium perfringens upregulate endothelial cell - Leukocyte adherence molecule 1 and intercellular leukocyte adherence molecule 1 expression and induce interleukin-8 synthesis in cultured human umbilical vein endothelial cells
    • Bryant AE, Stevens DL. Phospholipase C and perfringolysin O from Clostridium perfringens upregulate endothelial cell - leukocyte adherence molecule 1 and intercellular leukocyte adherence molecule 1 expression and induce interleukin-8 synthesis in cultured human umbilical vein endothelial cells. Infect Immun 1996;64:358-62.
    • (1996) Infect Immun , vol.64 , pp. 358-362
    • Bryant, A.E.1    Stevens, D.L.2
  • 19
    • 0023816534 scopus 로고
    • Cloning and expression in Escherichia coli of the perfringolysin O (theta-toxin) gene from Clostridium perfringens and characterization of the gene product
    • Tweten RK. Cloning and expression in Escherichia coli of the perfringolysin O (theta-toxin) gene from Clostridium perfringens and characterization of the gene product. Infect Immun 1988;56:3228-34.
    • (1988) Infect Immun , vol.56 , pp. 3228-3234
    • Tweten, R.K.1
  • 20
    • 0023757453 scopus 로고
    • Nucleotide sequence of the gene for perfringolysin O (thetatoxin) from Clostridium perfringens: Significant homology with the genes for streptolysin O and pneumolysin
    • Tweten RK. Nucleotide sequence of the gene for perfringolysin O (thetatoxin) from Clostridium perfringens: significant homology with the genes for streptolysin O and pneumolysin. Infect Immun 1988;56:3235-40.
    • (1988) Infect Immun , vol.56 , pp. 3235-3240
    • Tweten, R.K.1
  • 21
    • 0024490943 scopus 로고
    • Cloning and expression of the phospholipase C gene from Clostridium perfringens and Clostridium bifermentans
    • Tso JY, Siebel C. Cloning and expression of the phospholipase C gene from Clostridium perfringens and Clostridium bifermentans. Infect Immun 1989;57:468-76.
    • (1989) Infect Immun , vol.57 , pp. 468-476
    • Tso, J.Y.1    Siebel, C.2
  • 22
    • 77957012032 scopus 로고
    • Spectrophotometric and turbidimetric methods for measuring proteins
    • Colowick SP, Kaplan ND, eds. New York: Academic Press
    • Layne E. Spectrophotometric and turbidimetric methods for measuring proteins. In: Colowick SP, Kaplan ND, eds. Methods in enzymology. New York: Academic Press, 1957:447-54.
    • (1957) Methods in Enzymology , pp. 447-454
    • Layne, E.1
  • 24
    • 0023142181 scopus 로고
    • Comparison of clindamycin, rifampin, tetracycline, metronidazole, and penicillin for efficacy in prevention of experimental gas gangrene due to Clostridium perfringens
    • Stevens DL, Maier KA, Laine BM, Mitten JE. Comparison of clindamycin, rifampin, tetracycline, metronidazole, and penicillin for efficacy in prevention of experimental gas gangrene due to Clostridium perfringens. J Infect Dis 1987;155:220-8.
    • (1987) J Infect Dis , vol.155 , pp. 220-228
    • Stevens, D.L.1    Maier, K.A.2    Laine, B.M.3    Mitten, J.E.4
  • 25
    • 0023141158 scopus 로고
    • Comparison of single and combination antimicrobial agents for prevention of experimental gas gangrene caused by Clostridium perfringens
    • Stevens DL, Laine BM, Mitten JE. Comparison of single and combination antimicrobial agents for prevention of experimental gas gangrene caused by Clostridium perfringens. Antimicrob Agents Chemother 1987;31: 312-6.
    • (1987) Antimicrob Agents Chemother , vol.31 , pp. 312-316
    • Stevens, D.L.1    Laine, B.M.2    Mitten, J.E.3
  • 27
    • 0027284577 scopus 로고
    • Evaluation of hyperbaric oxygen therapy for treatment of experimental Clostridium perfringens infection
    • Stevens DL, Bryant AE, Adams K, Mader JT. Evaluation of hyperbaric oxygen therapy for treatment of experimental Clostridium perfringens infection. Clin Infect Dis 1993;17:231-7.
    • (1993) Clin Infect Dis , vol.17 , pp. 231-237
    • Stevens, D.L.1    Bryant, A.E.2    Adams, K.3    Mader, J.T.4
  • 28
    • 80051933640 scopus 로고
    • The method of spread of gas gangrene into living muscle
    • McNee JW, Dunn JS. The method of spread of gas gangrene into living muscle. Br Med J 1917;1:727-9.
    • (1917) Br Med J , vol.1 , pp. 727-729
    • McNee, J.W.1    Dunn, J.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.