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1
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0343007299
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Abbreviations: D, dihydrouridine
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Abbreviations: D, dihydrouridine; EDTA, ethylenediamine tetraacetic acid; HIV, human immunodeficiency virus; mRNA, messenger ribonucleic acid; TΨC, ribothymidine-pseudouridine-cytidine loop; RNP, ribonucleoprotein; TAR, transactivation response element.
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EDTA, Ethylenediamine Tetraacetic Acid; HIV, Human Immunodeficiency Virus; mRNA, Messenger Ribonucleic Acid; TΨC, Ribothymidine-pseudouridine-cytidine Loop; RNP, Ribonucleoprotein; TAR, Transactivation Response Element
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Discussions relating to possible mechanisms for the transition from the RNA world to the theater of proteins have been published (see, for example refs 2-7).
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0343442974
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note
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A total of 43 solutions were obtained with coaxial stacking of the interduplex helix with the acceptor stem of microhelix-1. These solutions had the the 3′-ends of the acceptor stems constrained to within 15 Å, however. Distances less than 15 Å failed to yield solutions. For the 43 solutions obtained with a distance of 15 Å, the minor grooves of the acceptor stems were positioned to the interior of the complex where the phosphate backbones were brought into close proximity. This orientation was therefore considered unlikely to be productive for the purposes at hand.
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ds increase by about an order of magnutude.
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