Mild, selective cleavage of amino acid and peptide β-(trimethylsilyl)ethoxymethyl (SEM) esters by magnesium bromide

Tetrahedron Letters

Volumn 38, Issue 23, 1997, Pages 4025-4028

  Chen, Wei Chuan ^a   Vera, Matthew D ^a   Joullié, Madeleine M ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID DERIVATIVE; MAGNESIUM SALT; PEPTIDE;

ARTICLE; CATALYSIS; CHEMICAL REACTION; DRUG DEGRADATION; METHODOLOGY; PROTECTION;

EID: 0031007071     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0040-4039(97)00863-0     Document Type: Article

References (7)

1. Greene, T. W.; Wuts, P. G. M. Protective Groups in Organic Synthesis; John Wiley & Sons: New York, 1991.
2. Kocieński, P. J. Protecting Groups; Georg Thieme Verlag: New York, 1994.
3. Kim, S.; Park, Y. H.; Kee, I. S. Tetrahedron Lett. 1991, 32, 3099-3100.
4. Li, W.-R.; Ewing, W. R.; Harris, B. D.; Joullié, M. M. J. Am. Chem. Soc. 1990, 112, 7659-7672.
5. Fluka Chemika-Biochemika, 1993/94 catalog.
6. The value was obtained from the free acid before SEM protection.
7. Kisfaludy, L.; Schön, I. Synthesis 1983, 325-327.