Synthesis of (R) and (S) 14C-labelled ethyl nipecotate, for preparation of GABA uptake ligands

Journal of Labelled Compounds and Radiopharmaceuticals

Volumn 39, Issue 5, 1997, Pages 401-407

  Valsborg, Jacob S ^a   Foged, Christian ^a  

^a NOVO NORDISK A S   (Denmark)

Author keywords

13C; Chiral resolvation; Ethyl 3 carboxyl 14C piperidinecarboxylate; GABA; Gabitril ; Nipecotic acid; Tiagabine

Indexed keywords

CARBOXYLATION;

13C; CHIRAL HPLC; CHIRAL RESOLVATION; ETHYL 3-[CARBOXYL[14C]PIPERIDINECARBOXYLATE; GABA; GABITRIL®; NIPECOTIC ACID; RESOLVATION; SYNTHESISED; TIAGABINE;

CHELATION;

CARBON 14; NIPECOTIC ACID DERIVATIVE;

ARTICLE; CHIRALITY; DRUG PURIFICATION; DRUG SYNTHESIS; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; ISOTOPE LABELING; RADIOCHEMISTRY; THIN LAYER CHROMATOGRAPHY;

EID: 0031006505     PISSN: 03624803     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-1344(199705)39:5<401::AID-JLCR986>3.0.CO;2-V     Document Type: Article

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