메뉴 건너뛰기




Volumn 18, Issue 4, 1997, Pages 305-324

Pharmacokinetic stereoselectivity of troglitazone, an antidiabetic agent, in the KK mouse

Author keywords

epimerization; pharmacokinetics; stereoselectivity; troglitazone

Indexed keywords

ANTIDIABETIC AGENT; TROGLITAZONE;

EID: 0031006317     PISSN: 01422782     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1099-081X(199705)18:4<305::AID-BDD19>3.0.CO;2-L     Document Type: Article
Times cited : (15)

References (26)
  • 1
    • 0021961394 scopus 로고
    • Importance of drug enantiomers in clinical pharmacology
    • K. Williams and E. Lee, Importance of drug enantiomers in clinical pharmacology. Drugs, 30, 333-354 (1985).
    • (1985) Drugs , vol.30 , pp. 333-354
    • Williams, K.1    Lee, E.2
  • 2
    • 0023754239 scopus 로고
    • Stereoselectivity: An issue of significant importance in clinical pharmacology
    • Y. W. F. Lam, Stereoselectivity: an issue of significant importance in clinical pharmacology. Pharmacotherapy, 8, 147-157 (1988).
    • (1988) Pharmacotherapy , vol.8 , pp. 147-157
    • Lam, Y.W.F.1
  • 3
    • 0024948937 scopus 로고
    • Enantioselective aspects of drug action and disposition: Therapeutic Pitfalls
    • F. Jamali, R. Mehvar and F. M. Pasutto, Enantioselective aspects of drug action and disposition: Therapeutic Pitfalls. J. Pharm. Sci., 78, 695-715 (1989).
    • (1989) J. Pharm. Sci. , vol.78 , pp. 695-715
    • Jamali, F.1    Mehvar, R.2    Pasutto, F.M.3
  • 4
    • 0025286283 scopus 로고
    • Stereoselectivity in clinical pharmacokinetics and drug development
    • D. B. Campbell, Stereoselectivity in clinical pharmacokinetics and drug development. Eur. J. Drug Metab. Pharmacokinet., 35, 109-125 (1990).
    • (1990) Eur. J. Drug Metab. Pharmacokinet. , vol.35 , pp. 109-125
    • Campbell, D.B.1
  • 5
    • 0023132476 scopus 로고
    • Clearance approaches in Pharmacology
    • G. R. Wilkinson, Clearance approaches in Pharmacology. Pharmacol. Rev., 39, 1-47 (1987).
    • (1987) Pharmacol. Rev. , vol.39 , pp. 1-47
    • Wilkinson, G.R.1
  • 7
    • 0006014505 scopus 로고
    • Stereochemical consideration in drug metabolism
    • W. F. Trager and J. P. Jones, Stereochemical consideration in drug metabolism. Prog. Drug Metab., 10, 55-83 (1987).
    • (1987) Prog. Drug Metab. , vol.10 , pp. 55-83
    • Trager, W.F.1    Jones, J.P.2
  • 8
    • 0023835819 scopus 로고
    • The metabolic chiral inversion and dispositional enantioselectivity of the 2-arylpropionic acids and their biological consequences
    • J. Caldwell, A. J. Hutt and F. G. Fournel, The metabolic chiral inversion and dispositional enantioselectivity of the 2-arylpropionic acids and their biological consequences. Biochem. Pharmacol., 37, 105-114 (1988).
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 105-114
    • Caldwell, J.1    Hutt, A.J.2    Fournel, F.G.3
  • 9
    • 0025219446 scopus 로고
    • Epimerization and racemization of some chiral drugs in the presence of human serum albumin
    • Y. Aso, S. Yoshioka and Y. Takeda, Epimerization and racemization of some chiral drugs in the presence of human serum albumin. Chem. Pharm. Bull., 38, 180-184 (1990).
    • (1990) Chem. Pharm. Bull. , vol.38 , pp. 180-184
    • Aso, Y.1    Yoshioka, S.2    Takeda, Y.3
  • 10
    • 0026540991 scopus 로고
    • Determination of tolperisone enantiomers in plasma and their disposition in rats
    • T. Yokoyama, K. Fukuda, S. Mori, M. Ogawa and K. Nasagawa, Determination of tolperisone enantiomers in plasma and their disposition in rats. Chem. Pharm. Bull., 40, 272-274 (1992).
    • (1992) Chem. Pharm. Bull. , vol.40 , pp. 272-274
    • Yokoyama, T.1    Fukuda, K.2    Mori, S.3    Ogawa, M.4    Nasagawa, K.5
  • 12
    • 0028220747 scopus 로고
    • Investigations on the in vitro racemization of thalidomide by high-performance liquid chromatography
    • B. Knoche and G. Blaschke, Investigations on the in vitro racemization of thalidomide by high-performance liquid chromatography. J. Chromatogr., 666, 235-240 (1994).
    • (1994) J. Chromatogr. , vol.666 , pp. 235-240
    • Knoche, B.1    Blaschke, G.2
  • 13
    • 0024160854 scopus 로고
    • Characterization of new antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats
    • T. Fujiwara, S. Yoshioka, T. Yoshioka, I. Ushiyama and H. Horikoshi, Characterization of new antidiabetic agent CS-045. Studies in KK and ob/ob mice and Zucker fatty rats. Diabetes, 37, 1549-1558 (1988).
    • (1988) Diabetes , vol.37 , pp. 1549-1558
    • Fujiwara, T.1    Yoshioka, S.2    Yoshioka, T.3    Ushiyama, I.4    Horikoshi, H.5
  • 14
    • 0025938575 scopus 로고
    • Characterization of CS-045, a new oral antidiabetic agent. II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57 BL/KsJ-db/db mice
    • T. Fujiwara, M. Wada, K. Fukuda, M. Fukami, S. Yoshioka, T. Yoshida and H. Horikoshi, Characterization of CS-045, a new oral antidiabetic agent. II. Effects on glycemic control and pancreatic islet structure at a late stage of the diabetic syndrome in C57 BL/KsJ-db/db mice. Metabolism, 40, 1213-1218 (1991).
    • (1991) Metabolism , vol.40 , pp. 1213-1218
    • Fujiwara, T.1    Wada, M.2    Fukuda, K.3    Fukami, M.4    Yoshioka, S.5    Yoshida, T.6    Horikoshi, H.7
  • 15
    • 0026517631 scopus 로고
    • Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects
    • J. Suter, J. Nolan, P. Wallace, B. Bumbiner and J. M. Olefsky, Metabolic effects of new oral hypoglycemic agent CS-045 in NIDDM subjects. Diabetes Care, 15, 193-203 (1992).
    • (1992) Diabetes Care , vol.15 , pp. 193-203
    • Suter, J.1    Nolan, J.2    Wallace, P.3    Bumbiner, B.4    Olefsky, J.M.5
  • 16
    • 0024580477 scopus 로고
    • Determination of free drug in protein binding equilibrium by high-performance frontal analysis using internal-surface reversed-phase support
    • A. Shibukawa, T. Sawada, N. Nishimura, M. Miyake and H. Tanaka, Determination of free drug in protein binding equilibrium by high-performance frontal analysis using internal-surface reversed-phase support. Chem. Pharm. Bull., 37, 702-706 (1989).
    • (1989) Chem. Pharm. Bull. , vol.37 , pp. 702-706
    • Shibukawa, A.1    Sawada, T.2    Nishimura, N.3    Miyake, M.4    Tanaka, H.5
  • 17
    • 0027932264 scopus 로고
    • Determination of unbound concentration of hydrophobic drugs in albumin solution by high-performance frontal analysis using a diol-silica column
    • A. Shibukawa, C. Nakao, T. Sawada, N. Morokoshi and T. Nakagawa, Determination of unbound concentration of hydrophobic drugs in albumin solution by high-performance frontal analysis using a diol-silica column. J. Pharm. Sci., 83, 868-876 (1994).
    • (1994) J. Pharm. Sci. , vol.83 , pp. 868-876
    • Shibukawa, A.1    Nakao, C.2    Sawada, T.3    Morokoshi, N.4    Nakagawa, T.5
  • 18
    • 0028903834 scopus 로고
    • High-performance frontal analysis for the study of protein binding of troglitazone (CS-045) in albumin solution and human plasma
    • A. Shibukawa, T. Sawada, C. Nakao, T. Izumi and T. Nakagawa, High-performance frontal analysis for the study of protein binding of troglitazone (CS-045) in albumin solution and human plasma. J. Chromatogr. A, 697, 337-347 (1995).
    • (1995) J. Chromatogr. A , vol.697 , pp. 337-347
    • Shibukawa, A.1    Sawada, T.2    Nakao, C.3    Izumi, T.4    Nakagawa, T.5
  • 19
    • 0342737812 scopus 로고    scopus 로고
    • Prediction of the human pharmacokinetics of troglitazone, a new and extensively metabolized antidiabetic agent, after oral administration, using an animal scale-up approach
    • in press
    • T. Izumi, S. Enomoto, K. Hoshiyama, K. Sasahara, A. Shibukawa, T. Nakagawa and Y. Sugiyama, Prediction of the human pharmacokinetics of troglitazone, a new and extensively metabolized antidiabetic agent, after oral administration, using an animal scale-up approach. J. Pharm. Exp. Ther., in press.
    • J. Pharm. Exp. Ther.
    • Izumi, T.1    Enomoto, S.2    Hoshiyama, K.3    Sasahara, K.4    Shibukawa, A.5    Nakagawa, T.6    Sugiyama, Y.7
  • 20
    • 0027275566 scopus 로고
    • Physiological parameters in laboratory animals and humans
    • B. Davies and T. Morris, Physiological parameters in laboratory animals and humans. Pharm. Res., 10, 1093-1095 (1993).
    • (1993) Pharm. Res. , vol.10 , pp. 1093-1095
    • Davies, B.1    Morris, T.2
  • 21
    • 0021715682 scopus 로고
    • Studies on antidiabetic agents. VI. Asymmetric transformation of (±)-4-[4-(1-methyl cyclohexylmethoxy)benzyl]-2,4-thiazolidinedione (ciglitazone) with optically active 1-phenylethylamines
    • T. Sohda, K. Mizuno and Y. Kawamatsu, Studies on antidiabetic agents. VI. Asymmetric transformation of (±)-4-[4-(1-methyl cyclohexylmethoxy)benzyl]-2,4-thiazolidinedione (ciglitazone) with optically active 1-phenylethylamines. Chem. Pharm. Bull., 32, 4460-4465 (1984).
    • (1984) Chem. Pharm. Bull. , vol.32 , pp. 4460-4465
    • Sohda, T.1    Mizuno, K.2    Kawamatsu, Y.3
  • 23
    • 0021806850 scopus 로고
    • The rate of molecular evolution of a-fetoprotein approaches that of pseudogenes
    • P. P. Minghetti, S. W. Law and A. Dugaiczk, The rate of molecular evolution of a-fetoprotein approaches that of pseudogenes. Mol. Biol. Evol., 2, 347-348 (1985).
    • (1985) Mol. Biol. Evol. , vol.2 , pp. 347-348
    • Minghetti, P.P.1    Law, S.W.2    Dugaiczk, A.3
  • 24
    • 0030995272 scopus 로고    scopus 로고
    • Determination of protein binding of troglitazone stereoisomers by fluorometric titration
    • submitted
    • T. Izumi, K. Hoshiyama, K. Sasahara and Y. Sugiyama, Determination of protein binding of troglitazone stereoisomers by fluorometric titration. Biopharm. Drug Disposit., submitted.
    • Biopharm. Drug Disposit.
    • Izumi, T.1    Hoshiyama, K.2    Sasahara, K.3    Sugiyama, Y.4
  • 25
    • 0027331597 scopus 로고
    • Pharmacokinetics of reversible metabolic systems
    • H. Cheng and W. J. Jusko, Pharmacokinetics of reversible metabolic systems. Biopharm. Drug Disposit., 14, 721-766 (1993).
    • (1993) Biopharm. Drug Disposit. , vol.14 , pp. 721-766
    • Cheng, H.1    Jusko, W.J.2
  • 26
    • 0022859808 scopus 로고
    • The determination of essential clearance, volume, and residence time parameters of recirculating metabolic systems: The reversible metabolism of methylprednisolone and methylprednisone in rabbits
    • W. F. Ebling and W. J. Jusko, The determination of essential clearance, volume, and residence time parameters of recirculating metabolic systems: the reversible metabolism of methylprednisolone and methylprednisone in rabbits. J. Pharmacokinet. Biopharm., 14, 577-590 (1986).
    • (1986) J. Pharmacokinet. Biopharm. , vol.14 , pp. 577-590
    • Ebling, W.F.1    Jusko, W.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.