Low molecular weight protein excretion in glomerular disease: A comparative analysis

Pediatric Nephrology

Volumn 11, Issue 3, 1997, Pages 285-290

  Tomlinson, P A ^a,b   Dalton, R N ^a   Hartley, B ^a   Haycock, G B ^a   Chantier, C ^a  

^a GUY S HOSPITAL   (United Kingdom)

^b SOUTHLAND HOSPITAL   (New Zealand)

Author keywords

1 microglobulin; 2 microglobulin; Glomerular diseases; N acetyl D glucosaminidase; Retinol protein 1; Retinol binding protein; Urine protein

Indexed keywords

ALPHA 1 MICROGLOBULIN; BETA 2 MICROGLOBULIN; N ACETYL BETA GLUCOSAMINIDASE; RETINOL BINDING PROTEIN; SYNAPSIN I;

ARTICLE; CHILD; CONTROLLED STUDY; GLOMERULUS; GLOMERULUS FILTRATION RATE; HUMAN; HUMAN TISSUE; KIDNEY BIOPSY; KIDNEY DISEASE; KIDNEY TUBULE ABSORPTION; MAJOR CLINICAL STUDY; MOLECULAR WEIGHT; NEPHRITIS; NEPHROTIC SYNDROME; PRIORITY JOURNAL; PROGNOSIS; PROTEIN BLOOD LEVEL; PROTEIN URINE LEVEL; PROTEINURIA; URINARY EXCRETION; URINE PH;

ALBUMINURIA; BIOLOGICAL MARKERS; CHILD; CREATININE; GLOMERULONEPHRITIS; HUMANS; KIDNEY; MOLECULAR WEIGHT; NEPHROTIC SYNDROME; PROTEINURIA; STEROIDS;

EID: 0031006238     PISSN: 0931041X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004670050278     Document Type: Article

References (35)

1. Risdon RA, Sloper JC, De Wardener HE (1968) Relationship between renal function and histological changes found in renalbiopsy specimens from patients with persistent glomerular nephritis. Lancet II: 363-366
2. 2-microglobulin to diagnose tubulo-interstitial renal lesions in children. Kidney Int 30: 91-98
3. Tomlinson PA (1992) Low molecular weight proteins in children with renal disease. Pediatr Nephrol 6: 565-571
4. Brocklebank T, Cooper EH, Richmond K (1991) Sodium dodecyl sulphate polyacrylamide gel electrophoresis patterns of proteinuria in various renal diseases of childhood. Pediatr Nephrol 5: 371-375
5. 2-Microglobulin instability in pathological urine. Clin Chem 28: 1330-1333
6. Bernard AM, Vyskocil AA, Mahieu P, Lauwerys RR (1987) Assessment of urinary retinol-binding protein as an index of proximal tubular injury. Clin Chem 33: 775-779
7. Yu H, Yanagisawa Y, Forbes MA, Cooper EH, Crockson RA (1983) Alpha-1-microglobulin: an indicator protein for renal tubular function. J Clin Pathol 36: 253-259
8. 2-microglobulin determination in urine for the early detection of tubular proteinuria. Clin Chim Acta 126: 1-7
9. 2-microglobulin and retinol-binding protein in urine. Clin Chim Acta 179: 73-78
10. Bernard AM, Lauwerys RR, Noel A, Vandeleene B, Lambert A (1989) Urine protein 1: a sex-dependent marker of tubular or glomerular dysfunction. Clin Chem 35: 2141-2142
11. Bernard AM, Roels H, Cardenas A, Lauwerys R (1990) Assessment of urinary protein 1 and transferrin as early markers of cadmium nephrotoxicity. Br J Ind Med 47: 559-565
12. 2-microglobulin, albumin, and total protein. J Clin Invest 48. 1189-1198
13. Grillenberger A, Weninger M, Lubec G (1987) Determination of urinary low molecular weight proteins for the diagnosis of tubular damage. Padiatr Padol 22: 229-234
14. 2-microglobulin and retinol binding protein in childhood febrile illness and renal disease. Pediatr Nephrol 4: 314-318
15. Churg J, Habib R, White RHR (1970) Pathology of the nephrotic syndrome in children. Lancet I: 1299-1302
16. Beetham R, Newman D (1992) Urinary albumin and low molecular weight protein excretion in the nephrotic syndrome - sequential studies during corticosteroid treatment. Ann Clin Biochem 29: 450-453
17. 1-microglobulin and urine protein 1 in healthy children using enzyme-linked immunosorbent assay. Clin Chim Acta 192: 99-106
18. Tomlinson PA (1996) The use of low molecular weight proteins in the diagnosis of renal tubular dysfunction in children. MD Thesis. University of Auckland
19. Chantier C, Barratt TM (1972) Estimation of glomerular filtration rate from plasma clearance of 51-chromium edetic acid. Arch Dis Child 47: 613-617
20. Morris MC, Allanby, Toseland P, Haycock GB, Chantler C (1982) Evaluation of a height/plasma creatinine formula in the measurement of glomerular filtration rate. Arch Dis Child 57: 611-615
21. Cameron JS (1992) Tubular and interstitial factors in the progression of glomerulonephritis Pediatr Nephrol 6: 292-303
22. Trompeter RS, Lloyd BW, Hicks J, White RHR, Cameron JS (1985) Long-term outcome for children with minimal-change nephrotic syndrome. Lancet I. 368-370
23. Robson AM, Giangiacomo J, Kienstra RA, Naqvi ST, Ingelfinger JR (1974) Normal glomerular permeability and its modification by minimal change nephrotic syndrome. J Clin Invest 54: 1190-1199
24. Piqueras AI, Shah V, Hulton SA, Barratt TM, Dillon MJ (1993) Tubular proteinuria in steroid-sensitive multi-relapsing nephrotic syndrome. Clin Nephrol 40: 26-30
25. Bouissou F, Barthe P, Pierragi MT (1980) Severe idiopathic nephrotic syndrome with tubular dysfunction (report of 9 pediatric cases). Clin Nephrol 14: 135-141
26. McVicar M, Exeni R, Susin M (1980) Nephrotic syndrome and multiple tubular defects in children: an early sign of focal segmental glomerulosclerosis. J Pediatr 97: 918-922
27. Sesso R, Santos AP, Nishida SK, Klag MJ, Caralhaes JT, Ajzen H, Ramos OL, Pereira AB (1992) Prediction of steroid responsiveness in the idiopathic nephrotic syndrome using urinary retinol-binding protein and beta-2-microglobulin. Ann Intern Med 116. 905-909
28. Rask L, Anundi H, Bohme J, Eriksson U, Fredriksson A, Nilsson SF, Ronne H, Vahlquist A, Peterson PA (1980) The retinol-binding protein. Scand J Clin Lab Invest 40 [Suppl 154]: 45-61
29. Cameron JS, White RHR (1965) Selectivity of proteinuria in children with the nephrotic syndrome. Lancet I: 463-465
30. Scarpioni L, Dall'aglio PP, Poisetti PG, Buzio C (1976) Retinolbinding protein in serum and in urine of glomerular and tubular nephropathies. Clin Chim Acta 68: 107-113
31. 2-microglobulin and lysozyme in renal disease. Scand J Urol Nephrol 6. 249-256
32. Tomlinson PA, Smellie JM, Prescod NP, Dalton RN, Chantler C (1994) Differential excretion of urinary proteins in children with vesicoureteric reflux and reflux nephropathy. Pediatr Nephrol 8: 21-25
33. Bernard A, Vyskocyl A, Mahieu P, Lauwerys R (1988) Effect of renal insufficiency on the concentration of free retinol-binding protein in urine and serum. Clin Chim Acta 171: 85-94
34. Blantz RC, Pelayo JC, Gushwa LC, Myers RR, Evan AP (1985) Functional basis for the glomerular alterations in uranyl nitrate acute renal failure. Kidney Int 28: 733-743
35. Kunin CM, Chesney RW, Craig WA, England AC, DeAngelis C (1978) Enzymuria as a marker of renal injury and disease: studies of N-acetyl-β-D-glucosaminidase in the general population and in patients with renal disease. Pediatrics 62: 751-760