Characterization and cellular distribution of the osteoclast ruffled membrane vacuolar H+-ATPase B-subunit using isoform-specific antibodies

Journal of Bone and Mineral Research

Volumn 12, Issue 5, 1997, Pages 753-760

  Mattsson, Jan P ^a   Skyman, Christine ^a   Palokangas, Harri ^b   Väänänen, Kalervo H ^b   Keeling, David J ^a  

^a ASTRAZENECA R AND D   (Sweden)

^b UNIVERSITY OF OULU   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CLATHRIN; COMPLEMENTARY DNA; MESSENGER RNA; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARTICLE; BETA CHAIN; CATALYSIS; CATTLE; CHICKEN; CONFOCAL MICROSCOPY; ENZYME ACTIVITY; IMMUNOBLOTTING; IMMUNOCYTOCHEMISTRY; NONHUMAN; OSTEOCLAST; OSTEOLYSIS; STRUCTURE ACTIVITY RELATION;

EID: 0031006179     PISSN: 08840431     EISSN: None     Source Type: Journal    
DOI: 10.1359/jbmr.1997.12.5.753     Document Type: Article

References (33)

1. Vaes G 1988 Cellular biology and biochemical mechanism of bone resorption: A review of recent developments on the formation, activation, and mode of action of osteoclasts. Clin Orthop Relat Res 231:239-271.
2. Blair HC, Kahn AJ, Crouch EC, Jeffrey JJ, Teitelbaum SL 1986 Isolated osteoclasts resorb the organic and inorganic components of bone. J Cell Biol 102:1164-1172.
3. Blair HC, Teitelbaum SL, Ghiselli R, Gluck S 1989 Osteoclastic bone resorption by a polarized vacuolar proton pump. Science 245:855-857.
4. +-ATPase of avian osteoclast ruffled membrane. Am J Physiol 260:C1315-C1324.
5. +-ATPase type in the ruffled borders of osteoclasts. J Cell Biol 111:1305-1311.
6. Bekker PJ, Gay CV 1990 Biochemical characterization of an electrogenic vacuolar proton pump in purified chicken osteoclast plasma membrane vesicles. J Bone Miner Res 5:569-579.
7. +-translocating ATPases. Biochim Biophys Acta 1065:261-268.
8. Mattsson JP, Lorentzon P, Wallmark B, Keeling DJ 1993 Characterization of proton transport in bone-derived membrane vesicles. Biochim Biophys Acta 1146:106-112.
9. Mattsson JP, Schlesinger PH, Keeling DJ, Teitelbaum SL, Stone DK, Xie XS 1994 Isolation and reconstitution of a vacuolar-type proton pump of osteoclast membranes. J Biol Chem 269:24979-24982.
10. +-ATPases. Proc Natl Acad Sci USA 89:6257-6261.
11. Forgac M 1989 Structure and function of vacuolar class of ATP-driven proton pumps. Physiol Rev 69:765-796.
12. Gluck S, Al-Awqati Q 1984 An electrogenic proton-translocating adenosine triphosphatase from bovine kidney medulla. J Clin Invest 73:1704-1710.
13. +-ATPase regulates cytoplasmic pH in murine macrophages. J Biol Chem 265:7645-7654.
14. 2+-activated ATP hydrolysis. J Biol Chem 263:9859-9867.
15. + channel of vacuolar proton pumps. J Biol Chem 269:17379-17381.
16. +-ATPase. J Biol Chem 65:17428-17431.
17. +-ATPase in bovine tissues. J Biol Chem 267:3696-3706.
18. +-ATPase 56-kilodalton subunit in renal intercalated cells. Proc Natl Acad Sci USA 89:3541-3545.
19. Gluck SL, Nelson RD, Lee BS, Wang ZQ, Guo JR, Fu JY, Zhang K 1992 Biochemistry of the renal V-ATPase. J Exp Biol 172:219-229.
20. +-ATPase: Differential expression of two human subunit B isoforms. Biochem J 303:191-198.
21. Wang ZQ, Gluck S 1990 Isolation and properties of bovine kidney brush border vacuolar H(+)-ATPase: A proton pump with enzymatic and structural differences rom kidney microsomal H(+)-ATPase. J Biol Chem 265:21957-21965.
22. Xie XS, Stone DK 1986 Isolation and reconstitution of the clathrin-coated vesicle proton translocating complex. J Biol Chem 261:2492-2495.
23. Löwenadler B, Jansson B, Paleus S, Holmgren E, Nilsson B, Moks T, Palm G, Josephson S, Philipson, Uhlèn M 1987 A gene fusion system for generating antibodies against short peptides. Gene 58:87-97.
24. +-ATPase. Biochim Biophys Acta 1280:98-106.
25. Laemmli UK 1970 Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227:680-685.
26. Lakkakorpi P, Tuukkanen J, Hentunen T, Jarvelin K, Väänänen K 1989 Organization of osteoclast rnicrofilaments during the attachment to bone surface in vitro. J Bone Miner Res 4:817-825.
27. Helfrich MH, Nesbitt SA, Horton MA 1992 Integrins on rat osteoclasts: Characterization of two monoclonal antibodies (F4 and F11) to rat beta 3. J Bone Miner Res 7:345-351.
28. Schaffner W, Weissmann C 1973 A rapid, sensitive, and specific method for the determination of protein in dilute solution. Anal Biochem 56:502-514.
29. +-ATPases. Biochemistry 32:2808-2812.
30. +-ATPase. Comparison of proton transport in kidney- and osteoclast-derived vesicles. J Biol Chem 269:30158-30163.
31. +-ATPase B-subunit. Gene 160:157-164.
32. Lakkakorpi PT, Helfrich MH, Horton MA, Väänänen HK 1993 Spatial organization of microfilaments and vitronectin receptor, alpha v beta 3, in osteoclasts. A study using confocal laser scanning microscopy. J Cell Sci 104:663-670.
33. +-ATPase in osteoclasts and its role in resorption. Cell Tissue Res 278:265-271.