Effect of clozapine on dopamine-induced inhibition of prolactin release from cultured rat pituitary cells

Pharmacological Research

Volumn 35, Issue 3, 1997, Pages 173-175

  Braghiroli, L ^a   Ponzianelli, A ^a   Fiani, M ^b   De Feo, G ^a   Cheng, C Y ^c   Mazzanti, G ^a  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b ISTITUTO SUPERIORE DI SANITÀ   (Italy)

^c ROCKEFELLER UNIVERSITY   (United States)

Author keywords

Cell culture; Clozapine; Dopamine; Prolactin; Rat

Indexed keywords

CHLORPROMAZINE; CLOZAPINE; DOPAMINE; DOPAMINE RECEPTOR; FLUPHENAZINE; NEUROLEPTIC AGENT; PROLACTIN;

ANIMAL CELL; ARTICLE; CELL CULTURE; CONTROLLED STUDY; DRUG POTENCY; FEMALE; HYPERPROLACTINEMIA; HYPOPHYSIS; HYPOPHYSIS CELL; NONHUMAN; PRIORITY JOURNAL; PROLACTIN BLOOD LEVEL; PROLACTIN RELEASE; RAT;

EID: 0031006152     PISSN: 10436618     EISSN: None     Source Type: Journal    
DOI: 10.1006/phrs.1996.0102     Document Type: Article

References (12)

1. Meltzer HY, Goode DJ, Fang VS. The effect of psychotropic drugs on endocrine function. Psycopharmacology: A Generation of Progress. 1978;Raven Press, New York.
2. Kane J, Honigfeld G, Singer J, Meltzer H, Clozaril CSG. Clozapine for the treatment-resistant schizophrenic. Arch Gen Psychiatry. 45:1988;789-796.
3. Pickar D, Owen RR, Litman RE, Konicki E, Gutierrez R, Rapaport MH. Clinical and biologic response to clozapine in patients with schizophrenia. Crossover comparison with fluphenazine. Arch Gen Psychiatry. 49(5):1993;345-353.
4. Meltzer HY, Daniels S, Fang VS. Clozapine increases rat serum prolactin levels. Life Sci. 17:1975;339-342.
5. Meltzer HY, So R, Miller RJ, Fang VS. Comparison of the effect of substituted benzamides and standard neuroleptics on the binding of 3H-spiroperidol in the rat pituitary and striatum within vivo. Life Sci. 25:1979;573-584.
6. Lamberts SWJ, van Koetsveld PM, Hofland LJ. The effect of clozapine on prolactin secretion at the level of the lactotroph. Life Sci. 46:1990;1013-1019.
7. Giacomelli S, Braghiroli L, Ponzianelli A, Koppenaal DW, de Feo G. A sensitive assay for studying dopaminergic activity in pituitary cell culture. J Pharm Pharmacol. 49(3):1997;319-321.
8. Tallarida RJ, Murray RB. Manual of pharmacologic calculations. 1981;Springer-Verlag, Berlin.
9. Caron MG, Beaulieu M, Raymond V, Gagnè B, Drouin J, Lefkowitz RJ, Labrie F. Dopaminergic receptors in the anterior pituitary gland. J Biol Chem. 253:1978;2244-2253.
10. 2. Eur J Pharmacol. 236:1993;483-486.
11. 2. Brain Res. 564:1991;203-219.
12. 4. Nature. 350:1991;610-614.