Altered endothelial/pericyte ratio in Goto-Kakizaki rat retina

Journal of Diabetes and its Complications

Volumn 11, Issue 3, 1997, Pages 158-162

  Agardh, Carl David ^a   Agardh, Elisabet ^a   Zhang, Hui ^a   Östenson, Claes Göran ^b  

^a LUND UNIVERSITY HOSPITAL   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIABETIC RETINOPATHY; ENDOTHELIUM CELL; FEMALE; HYPERGLYCEMIA; IMPAIRED GLUCOSE TOLERANCE; INSULIN RESPONSE; KIDNEY DISEASE; MALE; NEUROPATHY; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PERICYTE; PRIORITY JOURNAL; RAT; RETINA BLOOD VESSEL; RETINA CELL; VASCULAR ENDOTHELIUM;

EID: 0031006055     PISSN: 10568727     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1056-8727(96)00049-9     Document Type: Article

References (22)

1. Klein R, Klein BEK, Moss SE: The Wisconsin Epidemiologic Study of Diabetic Retinopathy: A review: Diabetes Metab Rev 5:559-570, 1989.
2. Olk RJ, Lee CM: Classification of diabetic retinopathy, in Olk RJ, Lee CM (eds), Diabetic Retinopathy. Practical Management. Philadelphia, Lippincott, 1993, pp. 3-20.
3. Engerman RL: Animal Models of diabetic retinopathy. Trans Am Acad Ophthalmol Oto-Laryngol 81:710-715, 1976.
4. Chakrabarti S, Cherian PV, Sima AA: The effect of acarbose on diabetes- and age-related basement membrane thickening in retinal capillaries of the BB/W-rat. Diabetes Res Clin Pract 20:123-128, 1993.
5. Hammes H-P, Syed Ali S, Uhlmann M, Weiss A, Federlin K, Geisen K, Brownlee M: Aminoguanidine does not inhibit the initial phase of experimental diabetic retinopathy in rats. Diabetologia 38:269-273, 1995.
6. Engerman RL, Kern TS: Progression of incipient diabetic retinopathy during good glycemic control. Diabetes 36:808-812, 1987.
7. Kern TS, Engerman RL: Vascular lesions in diabetes are distributed non-uniformly within the retina. Exp Eye Res 60:545-549, 1995.
8. Danis RP, Yang Y: Microvascular retinopathy in the Zucker diabetic fatty rat. Invest Ophthalmol Vis Sci 34:2367-2371, 1993.
9. Kimura K, Toyota T, Kakizaki M, Kudo M, Takebe K, Goto Y: Impaired insulin secretion in the spontaneous diabetes rat. Tohuko J Exp Med 137:453-459, 1982.
10. Abdel-Halim SM, Guenifi A, Luthman H, Grill V, Efendic S, Östenson C-G: Impact of diabetic inheritance on glucose tolerance and insulin secretion in spontaneously diabetic GK-Wistar rats. Diabetes 43:281-288, 1994.
11. Östenson C-G, Khan A, Abdel-Halim SM, Guenifi A, Suzuki K, Goto Y, Efendic S: Abnormal insulin secretion and glucose metabolism in pancreatic islets from the spontaneously diabetic GK rat. Diabetologia 36:3-8, 1993.
12. Östenson C-G, Abdel-Halim SM, Rasschaert J, Malaisse-Lagae F, Meuris S, Sener A, Efendic S, Malaisse WJ: Deficient activity of FAD-linked glycerophosphate dehydrogenase in islets of GK rats. Diabetologia 36:722-726, 1993.
13. Goto Y, Kakizaki M, Yagihashi S: Neurological findings in spontaneously diabetic rats. Excerpta Med Int Cong Ser 581:26-38, 1982.
14. Goto Y, Suzuki K-I, Sasaki M, Ono T, Abe S: GK rat as a model of non obese non-insulin-dependent diabetes. Selective breeding over 35 generations. In: Shafrir E, Renold AE (eds), Frontiers in Diabetes Research. Lessons from Animal Models II. London, John Libbey and Co, 1988, pp. 301-303.
15. Suzuki K-I, Goto Y, Toyota T: Spontaneously diabetic GK (Goto-Kakizaki) rats. In: Shafrir E (ed), Lessons from Animal Diabetes IV. London, Smith-Gordon, 1992, pp. 107-116.
16. Kuwabara T, Cogan DG: Studies of retinal vascular patterns. I. Normal architecture. Arch Ophthalmol 64:904-911, 1960.
17. Suzuki K, Yen-Chung H, Toyota T, Goto Y, Hirata Y, Okada K: The significance of nerve sugar levels for the peripheral nerve impairmant of spontaneously diabetic GK (Goto-Kakizaki) rats. Diabetes Res 14:21-25, 1990.
18. Portha B, Serrads P, Bailbé D, Suzuki K, Goto Y, Giroix M-H: β-cell insensitivity to glucose in the GK rat, a spontaneous nonobese model for type II diabetes. Diabetes 40:486-491, 1991.
19. Apple DJ, Rabb MF: Ocular Pathology: Clinical Applications and Self Assessment, 3rd ed. St. Louis, CV Mosby, 1985, pp. 267-277.
20. Yanoff M, Fine B: Ocular Pathology: A Text and Atlas. Hagerstown, Maryland, Harper and Row, 1982, pp. 710-739.
21. Akagi Y, Kador PF: Effect of aldose reductase inhibitors on the progression of retinopathy in galactose-fed dogs. Exp Eye Res 50:635-639, 1990.
22. Robison WG Jr, McCaleb ML, Feld LG, Michaelis OE 4th, Laver N, Mercandetti M: Degenerated intramural pericytes ("ghost cells") in the retinal capillaries of diabetic rats. Curr Eye Res 10:339-350, 1991.