Investigation of primary tamoxifen therapy for elderly patients with operable breast cancer

Breast

Volumn 6, Issue 3, 1997, Pages 150-154

  Willsher, P C ^a,b   Robertson, J F R ^a   Jackson, L ^a   Al Hilaly, M ^a   Blarney, R W ^a  

^a NOTTINGHAM CITY HOSPITAL   (United Kingdom)

^b MOUNT SINAI HOSPITAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; TAMOXIFEN;

ADJUVANT CHEMOTHERAPY; AGED; ARTICLE; BREAST CANCER; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MASTECTOMY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL;

EID: 0031006008     PISSN: 09609776     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9776(97)90557-9     Document Type: Article

References (24)

1. Preece P E, Wood R A, Mackie C R, Cuschieri A. Tamoxifen as sole treatment of localised breast cancer in elderly women: a pilot study. BMJ 1982; 284: 871-872.
2. Gaskell D J, Hawkins R A, de Carteret S, Chetty U, Sangster K, Forrest APM. Indications for primary tamoxifen therapy in elderly women with breast cancer. Br J Surg 1992; 79: 1317-1320.
3. Morrow M. Breast disease in elderly women. Surg Clin North Am 1994; 74: 145-160.
4. Gaskell D J, Hawkins R A, de Carteret S, Chetty U, Sangster K, Forrest A P M. Indications for primary tamoxifen therapy in elderly women with breast cancer. Br J Surg 1992; 79: 1317-1320.
5. Horobin J M, Preece P E, Dewar J A, Wood R A B, Cuschieri A. Long-term follow-up of elderly patients with locoregional breast cancer treated with tamoxifen only. Br J Surg 1991; 78: 213-217.
6. Gazet J C, Ford H T, Coombes R C et al. Prospective randomized trial of tamoxifen vs. surgery in elderly patients with breast cancer. Eur J Surg Oncol 1994; 20: 207-214.
7. Fentiman I. Treatment of cancer in the elderly. Br J Cancer 1991; 64: 993-995.
8. Robertson J F R, Ellis I O, Elston C W, Blarney R W. Mastectomy or tamoxifen as initial therapy for operable breast cancer in elderly patients: 5-year follow-up. Eur J Cancer 1992; 28A: 908-910.
9. Robertson J F R, Todd J H, Ellis I O, Elston C W, Blamey R W. Comparison of mastectomy with tamoxifen for treating elderly patients with operable breast cancer. BMJ 1988; 297: 511-514.
10. Hayward J L, Carbone P P, Heuson J C, Kumaoka S, Rubens R. Assessment of response to therapy in advanced breast cancer: a project of the Programme on Clinical Oncology of the International Union Against Cancer, Geneva, Switzerland. Cancer 1977; 39: 1289-1294.
11. Nicholson R I, Colin P, Francis A B et al. Evaluation of an enzyme immunoassay for oestrogen receptors in human breast cancers. Cancer Res. (Supp). 1986; 46: 4299s-4304s.
12. Riley D, Bates T, Houghton J. Breast cancer in the elderly patient - the case for clinical trials (Abstract). The Breast 1995; 4: 253.
13. Bergman L, van Dongen J A, van Ooijen B, van Leeuwen F E. Should tamoxifen be a primary treatment choice for elderly breast cancer patients with locoregional disease. Br Cancer Res Treat 1995; 34: 77-83.
14. Bates T, Riley D, Houghton J, Baum M. Tamoxifen treatment for breast cancer in elderly patients. Br J Surg 1992; 79: Abstract 454.
15. Dixon J M. Treatment of elderly patients with breast cancer. BMJ 1992; 304: 996-997.
16. Martelli G, DePalo G, Rossi N et al. Long-term follow-up of elderly patients with operable breast cancer treated with surgery without axillary dissection plus adjuvant tamoxifen. Br J Cancer 1995; 72: 1251-1255.
17. Allan S G, Rodger A, Smyth J F, Leonard R C F, Chetty U, Forrest APM. Tamoxifen as primary treatment of breast cancer in elderly or frail patients: a practical management. BMJ 1985; 290: 358.
18. Gaskell D J, Hawkins R A, Sangsteri K, Chetty U. Relation between immunocytochemical estimation of oestrogen receptor in elderly patients with primary breast cancer and response to tamoxifen. Lancet 1989; May 13: 1044-1046.
19. Low S C, Dixon A R, Bell J, Ellis I O, Elston C W, Robertson J F R, Blarney R W. Tumour oestrogen receptor content allows selection of elderly patients with breast cancer for conservative tamoxifen treatment. Br J Surg 1992; 79: 1314-1316.
20. Davies N, Moir G, Carpenter R, Cuthbert A, Herbert A, Royle G T, Taylor I. ERICA predicts response to tamoxifen in elderly women with breast cancer. Ann RCS Eng 1991; 73: 361-363.
21. Robertson J F R, Williams M R. Todd J et al. Factors predicting the response of patients with advanced breast cancer to endocrine (Megace) therapy. Eur J Cancer Clin Oncol 1989; 23: 469-475.
22. Office of Population Census and Surveys. Mortality Series DH1, London, HMSO. 1992.
23. Bates T, Riley D, Houghton J, Baum M. Tamoxifen treatment for breast cancer in elderly patients. Br J Surg 1992; 79: Abstract 454.
24. Cuzick J, Baum M. Tamoxifen and contralateral breast cancer. Lancet 1985; 1: 282.