Species-specificity of pyrimethamine in the rodent bone marrow micronucleus test

Mutation Research - Genetic Toxicology and Environmental Mutagenesis

Volumn 390, Issue 1-2, 1997, Pages 167-170

  Ono, Tomoko ^a   Sekiya, Tatsuro ^a   Takahashi, Yoshiyuki ^a   Sasaki, Yu F ^b   Ohta, Toshihiro ^c  

^a National Veterinary Assay Laboratory   (Japan)

^b HACHINOHE NATIONAL COLLEGE OF TECHNOLOGY   (Japan)

^c TOKYO UNIVERSITY OF PHARMACY AND LIFE SCIENCES   (Japan)

Author keywords

Clastogen; Micronucleus test; Pyrimethamine; Rat bone marrow

Indexed keywords

PYRIMETHAMINE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; MALE; MICRONUCLEUS TEST; MUTAGENICITY; NONHUMAN; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RAT; SPECIES DIFFERENCE;

ANIMALIA; CRICETINAE; CRICETULUS GRISEUS; RODENTIA;

EID: 0031005494     PISSN: 13835718     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-1218(97)00015-3     Document Type: Article

References (19)

1. Antoccia, A., F. Degrassi, A. Battistoni, P. Ciliutti and C. Tanzarella (1991) In vitro micronucleus test with kinetochore staining: evaluation of test performance, Mutagenesis, 6, 319-324.
2. Ëgeli, U. and G. Erdogan (1991) The clastogenic effect of pyrimethamine (Daraprim) on human chromosomes in lymphocyte cultures, Cell Biol. Toxicol., 7, 347-356.
3. Ono, T., M. Norimatsu and H. Yoshimura (1994) Induction of chromosome aberrations by pyrimethamine in cultured Chinese hamster (CHL) cells, Mutation Res., 323, 197-201.
4. Ono, T. and H. Yoshimura (1996) Analysis of micronucleus induction of pyrimethamine in in vitro CHL cells and in in vivo mouse bone marrow cells, Mutagenesis, 11, 85-88.
5. Izumi, H., E. Kokue and T. Hayama (1984) The critical period of pyrimethamine teratogenesis in the rat, Jpn. J. Vet. Sci., 46, 217-218.
6. Tangapregassom, A.M., M.J. Tangapregassom, C. Horvath, M. Trecul, M. Boucher-Ehrensperger and C. Petter (1985) Vascular anomalies and pyrimethamine-induced malformations in the rat, Teratogen. Carcinogen. Mutagen., 5, 55-62.
7. Horvath, C., A.M. Tangapregassom, M.J. Tangapregassom, M. Trecul, M. Boucher-Ehrensperger, A. Compagnon and C. Petter (1988) Pathogenesis of limb and facial malformations induced by pyrimethamine in the rat, Acta Morph. Hung., 36, 53-61.
8. Misawa, J., S. Kanda, E. Kokue, T. Hayama, S. Teramoto, H. Aoyama, M. Kaneda and T. Iwasaki (1982) Teratogenic activity of pyrimethamine in Gottingen minipig, Toxicol. Lett., 10, 51-54.
9. Yamamoto, Y., M. Ohnishi, E. Kokue, T. Hayama, H. Aoyama, M. Kaneda and S. Teramoto (1984) Pyrimethamine teratogenesis by short term administration in Goettingen miniature pig, Cong. Anom., 24, 83-87.
10. Sullivan, G.E. and E. Takacs (1971) Comparative teratogenicity of pyrimethamine in rats and hamsters, Teratology, 4, 205-210.
11. Harpey, J.P., Y. Darbois and G. Lefebvre (1983) Teratogenicity of pyrimethamine, Lancet, 2, 399.
12. Adler, I-D., U. Kliesch, P. van Hummelen and M. Kirsch-Volders (1991) Mouse micronucleus tests with known and suspect spindle poisons: results from two laboratories, Mutagenesis, 6, 47-53.
13. Gudi, R., J. Xu and A. Thilagar (1992) Assessment of the in vivo aneuploidy/micronucleus assay in mouse bone marrow cells with 16 chemicals, Environ. Mol. Mutagen., 20, 106-116.
14. Mailhes, J.B., M.J. Aardema and F. Marchetti (1993) Investigation of aneuploidy induction in mouse oocytes following exposure to vinblastine-sulfate, pyrimethamine, diethylstilbestrol diphosphate, or chloral hydrate, Environ. Mol. Mutagen., 22, 107-114.
15. Hayashi, M., T. Sofuni and M. Ishidate Jr. (1983) An application of acridine orange fluorescent staining to the micronucleus test, Mutation Res., 120, 241-247.
16. Kastenbaum, M.A. and K.O. Bowman (1970) Tables for determining the statistical significance of mutation frequencies, Mutation Res., 9, 527-549.
17. Albanese, R., E. Mirkova, D. Gatehouse and J. Ashby (1988) Species-specific response to the rodent carcinogens 1,2-dimethylhydrazine and 1,2-dibromo-3-chloropropane in rodent bone-marrow micronucleus assays, Mutagenesis, 3, 35-38.
18. George, E., M. Andrews and C. Westmoreland (1990) Effects of azobenzene and aniline in the rodent bone marrow micronucleus test, Carcinogenesis, 9, 1551-1555.
19. Westmoreland, C. and D.G. Gatehouse (1991) The differential clastogenicity of Solvent Yellow 14 and FD and C Yellow No. 6 in vivo in the rodent micronucleus test (observations on species and tissue specificity), Carcinogenesis, 12, 1403-1407.