Researchers in cell motility and the cytoskeleton can play major roles in understanding AIDS

Cell Motility and the Cytoskeleton

Volumn 37, Issue 2, 1997, Pages 91-97

  Soll, David R ^a  

^a UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACQUIRED IMMUNE DEFICIENCY SYNDROME; CELL FUSION; CELL MOTILITY; CYTOSKELETON; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; IMMUNOPATHOGENESIS; PRIORITY JOURNAL; REVIEW; SYNCYTIUM; T LYMPHOCYTE; VIRUS CELL INTERACTION;

ACQUIRED IMMUNODEFICIENCY SYNDROME; CELL DEATH; CELL MOVEMENT; CYTOSKELETON; GIANT CELLS; HIV ENVELOPE PROTEIN GP120; HIV-1; HUMANS; PHAGOCYTOSIS; T-LYMPHOCYTES;

HUMAN IMMUNODEFICIENCY VIRUS;

EID: 0031005278     PISSN: 08861544     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0169(1997)37:2<91::AID-CM1>3.0.CO;2-K     Document Type: Review

References (40)

1. Brynes, R.K., Chan, W.C., Spira, T.J., Ewing, E.P., and Chandler, F.W. (1983): Value of lymph node biopsy in unexplained lymphadenopathy in homosexual men. JAMA 250:1313-1317.
2. Center, D.M., and Cruikshank, W. (1982): Modulation of lymphocyte migration by himan lymphokines: I. Identification and characterization of chemoattractant activity for lymphocytes. J. Immunol. 128:2563-2568.
3. Dickson, D.W., Belman, A.L., Park, Y.D., Wiley, C., Horoupian, D.S., Llena, J., Kure, K., Lyman, W.D., Morecki, R., and Mitsudo, S. (1989): Central nervous system pathology in pediatric AIDS: An autopsy study. Acta Pathol. Microbiol. Immunol. Scand. (Suppl) 97:40-57.
4. Falkow, S. (1991): Bacterial entry into eukaryotic cells. Cell 65:1099-1102.
5. Frankel, S.S., Wenig, B.M., Burke, A.P., Mannan, P., Thompson, L.D.R., Abbondanzo, S.L., Nelson, A.M., Pope, M., and Steinman, R.M. (1996): Replication of HIV-1 in dendritic cell-derived syncytia at the mucosal surface of the adenoid. Science 272:115-117.
6. Gallo, R.C., and Montagnier, L. (1988). AIDS in 1988. Sci. Amer 259:40-48.
7. Joshi, V.V., MRCPath, Oleske, J.M., Minnefor, A.B., Singh, R., Bokhari, T., and Rapkin, R.H. (1984): Pathology of suspected acquired immune deficiency syndrome in children: A study of eight cases. Pediatr. Pathol. 2:71-87.
8. Keller, H.U., Borel, J.F., Wilkinson, P.C., Hess, M.W., and Cottier, H. (1972): Re-assessment of Boyden's technique for measuring chemotaxis. J. Immunol. Methods 1:165-168.
9. Koot, M., Keet, I.P., Vos, A.H., de goede, R.E., Roos, M.T., Coutinho, R.A., Miedema, F., Schellekens, P.T., and Tersmette, M. (1993); Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS. Ann. Intern. Med. 118:681-688.
10. Leonard, R., Zagury, D., Disportes, I., Bernard, J., Zagury, J.F., and Gallo, R.C. (1988): Cytopathic effect of human immunodeficiency virus in T4 cells is linked to the last stage of virus infection. PNAS 85:3570-3574.
11. Lewis, L., and Albrecht-Buehler, G. (1987): Distribution of multiple centrospheres determines micration of BHK syncytia. Cell Motil. Cytoskeleton 7:282-290.
12. Lewis-Alberti, L. (1989): Altering the vector of polarity of BHK syncytia changes their motile behavior. Cell Motil. Cytoskeleton 14:187-193.
13. Lifson, J.D., Reyes, G.R., McGrath, M.S., Stein, B.S., and Engleman, E.G. (1986): AIDS retrovirus induced cytopathology: Giant cell formation and involvement of CD4 antigen. Science 232:1123-1127.
14. Mackay, C.R. (1990): Chemokine receptors and T cell chemotaxis. J. Exptl. Med. 184:799-802.
15. Martin, S.J., Gougeon, M.L., and Montagnier, L. (1993). Programmed cell death and AIDS. Science 262:1355-1357.
16. Moskowitz, L.B., Hensley, G.T., Chan, J.C., Conley, F.K., Post, M.J. and Gonzales-Arias. S.M. (1984): The neuropathology of acquired immune deficiency syndrome: Analysis of 50 patients. Arch. Path. Lab. Med. 108:8-67.
17. + cells by HIV-induced T cell syncytia. AIDS Res. Hum. Retro. 11:433-442.
18. Pantaleo, G., Graziosi, C., and Fauci, A.S. (1993): The role of lymphoid organs in the pathogenesis of HIV infection. Sem. Immunol. 5:157-163.
19. Popovic, M., Sarngadharan, M.G., Read, E., and Gallo, R.C. (1984): Detection, isolation and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS. Science 224:497-500.
20. Rhodes, R.H. (1991): Evidence of serum-protein leakage across the blood-brain barrier in AIDS. J. Neuropathol. Exp. Neurol. 50:171-183.
21. Rinfret, A., Altendresse, H., Lefebure, R., St.-Louis, G., Jolicoeur, P., and Lamarre, L. (1991): Human Immunodeficiency Virus-infected multinucleated histiocytes in oropharyngeal lymphoid tissues from two asymptomatic patients. Am. J. Pathol. 138:421-426.
22. Rischman, D.D., and Bozette, S.A. (1994): The impact of the sycntyium-inducing phenotype of human immunodeficiency virus on disease progression. J. Infect. Dis. 169:968-974.
23. Shafer, R.W., Aguiniga, E., and Merigan, T.C. (1995): Quantitative analysis of syncytium-inducing (SI) and non-syncytium-inducing (NSI) virus in patients infected with HIV-1. J. Clin. Microbiol. 33:212-214.
24. Shall, T.J., Bacon, K.B., Toy, K.J., and Goehill, D.V. (1990): Selective attraction of monocytes and T lymphocytes of the memory phenotype of cytokine RANTES. Nature 345:669-671.
25. Sharer, L.R., Cho, E.-S., and Epstein, L.G. (1985): Multinucleated giant cells and HTLV-I II in AIDS encephalopathy. Hum. Pathol. 16:760-764.
26. Shutt, D., Stapleton, J., Kennedy, R., and Soll, D.R. (1995a): HIV-induced syncytia of peripheral blld T cells mimic the organization of individual cells and translocate through extension of giant pseudopodia. Cell. Immunol. 166:261-274.
27. Shutt, D., Wessels, D., Chandrasekhar, A., Luna, Bl, Hitt, A., and Soll, D.R. (1995b). Ponticulin plays a role in the spatial stabilization of pseudopods. J. Cell Biol. 131:1495-1506.
28. Soll, D.R., and Kennedy, R. (1994): The role of T cell motility and cytoskeletal reorganization in HIV-induced syncytium formation: A perspectus. AIDS Res. Hum. Retro. 10:325-327.
29. Sylwester, A. (1996): The in vitro biology of HIV-induced T cell syncytia. PhD Thesis. University of Iowa.
30. Sylwester, A., Shutt, D., Wessels, D., Stapleton, J.T., Stites, J., Kennedy, R., and Soll, D.R. (1995): T cells and HIV-induced T cell syncytia exhibit the motility cycle. J. Leuk. Biol. 57:643-650.
31. Sylwester, A., Wessels, D., Anderson, S.A., Warren, R.Q., Shutt, D., Kennedy, R., and Soll, D.R. (1493): HIV-induced syncytia of a T cell line form single giant pseudopods and are motile. J. Cell Science 106:941-953.
32. Sylwester, A., Shutt, D., Murphy, S., and Soll, D.R. (1997): HIV-induced T cell syncytia are self-perpetuating and the primary cause of T cell death in culture. J. Immunol. (in press).
33. Takeya, M., Naito, M., Eto, K., and Tåkahosi, K. (1991): Immunohistochemical characterization of multinucleated giant cells in the brain of a Japanese AIDS patient. Acta Pathol. Jpn. 41:212-216.
34. Tersmette, M. de Goede, R., Al. B.J., Winkel, I.N., Gruters, R.A., Cuypers, H.T., Huisman, H.G., and Miedema, F. (1988): Differential syncytium-inducing capacity of HIV isolates: Frequent detection of syncytium-inducing isolates in patients with AIDS and AIDS-related complex. J. Virol. 62:2026-2032.
35. Theriot, J.A. (1995): The cell biology of infection by intracellular bacterial pathogens. Ann. Rev. Dev. Biol. 11:213-239.
36. Varnum-Finney, B., Voss, E. and Soll, D.R. (1987): Frequency and orientation of pseudopod formation of Dictyostelium discoideum amebae chemotaxing in a spatial gradient: Further evidence for a temporal mechanism. Cell. Motil. Cytoskeleton 8:18-26.
37. Weissman, I.L. (1993): The whole body view: New insights into HIV pathogenesis are coming from studies of how the virus spreads within lymphoid organs in vivo and damages them. Curr. Biol. 3:766-769.
38. Wessels, D., Soil, D.R., Knecht, D., Loomis, W.F., DeLozanne, A., and Spudich, J. (1988): Cell motility and chemotaxis in Dictyostelium amebae lacking myosin heavy chain. Dev. Biol. 128:164-177.
39. Wilkenson, P.C. (1982): The measurement of leukocyte chemotaxis. J. Immunol. Methods 51:133-148.
40. Zigmond, S.H. (1977): Ability of polymorphonuclear leukocytes to orientate in gradients of chemotactic factors. J. Cell. Biol. 75:606-616.