Biopharmaceutical studies on drug/conjugated-metabolite interactions. III. Effect of acetaminophen sulfate and its positional isomers on the pharmacokinetics of acetaminophen in rats

Biological and Pharmaceutical Bulletin

Volumn 20, Issue 5, 1997, Pages 522-529

  Nakayama, Taiji ^a  

^a OKAYAMA UNIVERSITY   (Japan)

Author keywords

Acetaminophen; Acetaminophen sulfate; Drug conjugated metabolite interaction; Pharmacokinetics; Positional isomer; Rat

Indexed keywords

PARACETAMOL; PARACETAMOL SULFATE;

ANALGESIA; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BILIARY EXCRETION; BINDING COMPETITION; DRUG CLEARANCE; DRUG CONJUGATION; DRUG ELIMINATION; DRUG METABOLISM; INTRAVENOUS DRUG ADMINISTRATION; ISOMER; MALE; NONHUMAN; PLASMA PROTEIN BINDING; RAT; URINARY EXCRETION;

EID: 0031005276     PISSN: 09186158     EISSN: None     Source Type: Journal    
DOI: 10.1248/bpb.20.522     Document Type: Article

References (2)

1. Imamura Y., Nakamura H., Otagiri M., J. Pharmacobio-Dyn., 9, 694-696 (1986).
2. Etagere M., Nakamura H., Maruyama T., Imamura Y., Takadate Y., Chem. Pharm. Bull., 37, 498-501(1989).