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Volumn 29, Issue , 1997, Pages 263-284

Telomerase, checkpoints and cancer

Author keywords

[No Author keywords available]

Indexed keywords

TELOMERASE;

EID: 0031005220     PISSN: 02612429     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (79)

References (118)
  • 2
    • 0029145379 scopus 로고
    • Evidence for a critical telomere length in senescent human fibroblasts
    • Allsopp RC and Harley CB (1995) Evidence for a critical telomere length in senescent human fibroblasts. Experimental Cell Research 219 130-136
    • (1995) Experimental Cell Research , vol.219 , pp. 130-136
    • Allsopp, R.C.1    Harley, C.B.2
  • 3
    • 0029156035 scopus 로고
    • Telomere shortening is associated with cell division in vitro and in vivo
    • Allsopp RC, Chang E, Kashefi-Aazam M et al (1995) Telomere shortening is associated with cell division in vitro and in vivo. Experimental Cell Research 220 194-200
    • (1995) Experimental Cell Research , vol.220 , pp. 194-200
    • Allsopp, R.C.1    Chang, E.2    Kashefi-Aazam, M.3
  • 7
    • 0029154735 scopus 로고
    • Functional characterization and developmental regulation of mouse telomerase RNA
    • Blasco MA, Funk W, Villeponteau B and Greider CW (1995) Functional characterization and developmental regulation of mouse telomerase RNA. Science 269 1267-1270
    • (1995) Science , vol.269 , pp. 1267-1270
    • Blasco, M.A.1    Funk, W.2    Villeponteau, B.3    Greider, C.W.4
  • 8
    • 0030070054 scopus 로고    scopus 로고
    • Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis
    • Blasco MA, Rizen M, Greider CW and Hanahan D (1996) Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis. Nature Genetics 12 200-204
    • (1996) Nature Genetics , vol.12 , pp. 200-204
    • Blasco, M.A.1    Rizen, M.2    Greider, C.W.3    Hanahan, D.4
  • 12
    • 0027382875 scopus 로고
    • Dominant negative missense mutations in a novel yeast protein related to mammalian phosphitidylinositol 3-kinase and VP-S34 abrogate rapamycin cytotoxicity
    • Cafferkey R, Young PR, McLaughlin MM et al (1993) Dominant negative missense mutations in a novel yeast protein related to mammalian phosphitidylinositol 3-kinase and VP-S34 abrogate rapamycin cytotoxicity. Molecular Cell Biology 13 6012-6023
    • (1993) Molecular Cell Biology , vol.13 , pp. 6012-6023
    • Cafferkey, R.1    Young, P.R.2    McLaughlin, M.M.3
  • 13
    • 0030025660 scopus 로고    scopus 로고
    • Replicative senescence: An old lives' tale?
    • Campisi J (1996) Replicative senescence: an old lives' tale? Cell 84 497-500
    • (1996) Cell , vol.84 , pp. 497-500
    • Campisi, J.1
  • 14
    • 0021071034 scopus 로고
    • Diminished in-vitro kinase activity of the EGF receptor in senescent human fibroblasts
    • Carlin C, Phillips PD, Knowles BB and Cristofalo VJ (1983) Diminished in-vitro kinase activity of the EGF receptor in senescent human fibroblasts. Nature 306 617-620
    • (1983) Nature , vol.306 , pp. 617-620
    • Carlin, C.1    Phillips, P.D.2    Knowles, B.B.3    Cristofalo, V.J.4
  • 17
    • 0023710185 scopus 로고
    • Regulation of ornithine decarboxylase and other cell cycle-dependent genes during senescence of IMR-90 human diploid fibroblasts
    • Chang ZF and Chen KY (1988) Regulation of ornithine decarboxylase and other cell cycle-dependent genes during senescence of IMR-90 human diploid fibroblasts. Journal of Biological Chemistry 263 11431
    • (1988) Journal of Biological Chemistry , vol.263 , pp. 11431
    • Chang, Z.F.1    Chen, K.Y.2
  • 18
    • 0028345161 scopus 로고
    • Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells
    • Chen Q and Ames BN (1994) Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells. Proceedings of the National Academy of Sciences of the USA 91 4130-4134
    • (1994) Proceedings of the National Academy of Sciences of the USA , vol.91 , pp. 4130-4134
    • Chen, Q.1    Ames, B.N.2
  • 19
    • 0029940570 scopus 로고    scopus 로고
    • Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow
    • Chiu C-P, Dragowska W, Kim NW et al (1996) Differential expression of telomerase activity in hematopoietic progenitors from adult human bone marrow. Stem Cells 14 239-248
    • (1996) Stem Cells , vol.14 , pp. 239-248
    • Chiu, C.-P.1    Dragowska, W.2    Kim, N.W.3
  • 20
    • 0029586089 scopus 로고
    • A human telomeric protein
    • Chong L, Steensel B, Broccoli D et al (1995) A human telomeric protein. Science 270 1663-1667
    • (1995) Science , vol.270 , pp. 1663-1667
    • Chong, L.1    Steensel, B.2    Broccoli, D.3
  • 21
    • 0028990123 scopus 로고
    • Purification of tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme
    • Collins K, Kobayashi R and Greider CW (1995) Purification of tetrahymena telomerase and cloning of genes encoding the two protein components of the enzyme. Cell 81 677-686
    • (1995) Cell , vol.81 , pp. 677-686
    • Collins, K.1    Kobayashi, R.2    Greider, C.W.3
  • 23
    • 0026523228 scopus 로고
    • Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity
    • Counter CM, Avilion AA, LeFeuvre CE et al (1992) Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity. EMBO Journal 11 1921-1929
    • (1992) EMBO Journal , vol.11 , pp. 1921-1929
    • Counter, C.M.1    Avilion, A.A.2    LeFeuvre, C.E.3
  • 31
    • 0027520196 scopus 로고
    • Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere binding protein
    • Fang G and Cech TR (1993) Characterization of a G-quartet formation reaction promoted by the beta-subunit of the Oxytricha telomere binding protein. Biochemistry 32 11646-11657
    • (1993) Biochemistry , vol.32 , pp. 11646-11657
    • Fang, G.1    Cech, T.R.2
  • 32
    • 0029096515 scopus 로고
    • The RNA component of human telomerase
    • Feng J, Funk WD, Wang S-S et al (1995) The RNA component of human telomerase. Science 2691236- 1241
    • (1995) Science , vol.269 , pp. 1236-1241
    • Feng, J.1    Funk, W.D.2    Wang, S.-S.3
  • 33
    • 0027295499 scopus 로고
    • Failure of senescent human fibroblasts to express the insulin-like growth factor gene IGF-1
    • Ferber AC, Chang C, Sell A et al (1993) Failure of senescent human fibroblasts to express the insulin-like growth factor gene IGF-1. Journal of Biological Chemistry 268 17883-17888
    • (1993) Journal of Biological Chemistry , vol.268 , pp. 17883-17888
    • Ferber, A.C.1    Chang, C.2    Sell, A.3
  • 35
    • 0025838080 scopus 로고
    • Failure of senescent cells to phosphorylate the RB protein
    • Futreal PA and Barrett JC (1991) Failure of senescent cells to phosphorylate the RB protein. Oncogenee 1109-1113
    • (1991) Oncogene , vol.6 , pp. 1109-1113
    • Futreal, P.A.1    Barrett, J.C.2
  • 36
    • 0029119560 scopus 로고
    • CDC25 phosphatases as potential human oncogenes
    • Galaktionov K, Lee AK, Eckstein J et al (1995) CDC25 phosphatases as potential human oncogenes. Science 269 1575-1577
    • (1995) Science , vol.269 , pp. 1575-1577
    • Galaktionov, K.1    Lee, A.K.2    Eckstein, J.3
  • 37
    • 0029758451 scopus 로고    scopus 로고
    • FGF-1-dependent proliferative and migratory responses are impaired in senescent human umbilical vein endothelial cells and correlate with the inability to signal tyrosine phosphorylation of fibroblast growth factor receptor substrates
    • Garfinkel S, Hu X, Prudovsky IA et al (1996) FGF-1-dependent proliferative and migratory responses are impaired in senescent human umbilical vein endothelial cells and correlate with the inability to signal tyrosine phosphorylation of fibroblast growth factor receptor substrates. Journal of Cell Biology 134(3) 783-791
    • (1996) Journal of Cell Biology , vol.134 , Issue.3 , pp. 783-791
    • Garfinkel, S.1    Hu, X.2    Prudovsky, I.A.3
  • 38
    • 0024355439 scopus 로고
    • Increase in abundance of a transcript hybridizing to elongation factor 1 alpha during cellular senescence and quiescence
    • Giordano T, Kleinsek D and Foster DN (1989) Increase in abundance of a transcript hybridizing to elongation factor 1 alpha during cellular senescence and quiescence. Experimental Gerontology 24 501-513
    • (1989) Experimental Gerontology , vol.24 , pp. 501-513
    • Giordano, T.1    Kleinsek, D.2    Foster, D.N.3
  • 39
    • 0025145238 scopus 로고
    • Replicative senescence: The human fibroblast comes of age
    • Goldstein S (1990) Replicative senescence: the human fibroblast comes of age. Science 249 1129-1133
    • (1990) Science , vol.249 , pp. 1129-1133
    • Goldstein, S.1
  • 40
    • 1842344277 scopus 로고
    • TEL1, a gene involved in controlling telomere Ikength in S. cerevisiae is homologous to the ataxia telangectasia gene
    • Greenwall PW, Kronmal SL, Porter SE, Gassenhuber J, Obermaier B and Petes TD (1995) TEL1, a gene involved in controlling telomere Ikength in S. cerevisiae is homologous to the ataxia telangectasia gene. Cell 82 841-852
    • (1995) Cell , vol.82 , pp. 841-852
    • Greenwall, P.W.1    Kronmal, S.L.2    Porter, S.E.3    Gassenhuber, J.4    Obermaier, B.5    Petes, T.D.6
  • 42
    • 0022402513 scopus 로고
    • Identification of a specific telomere terminal transferase enzyme with two kinds of primer specificity
    • Greider CW and Blackburn EH (1985) Identification of a specific telomere terminal transferase enzyme with two kinds of primer specificity. Cell 51 405-413
    • (1985) Cell , vol.51 , pp. 405-413
    • Greider, C.W.1    Blackburn, E.H.2
  • 43
    • 0024978857 scopus 로고
    • A telomeric sequence in the RNA of tetrahymena telomerase required for telomere repeat synthesis
    • Greider CW and Blackburn EH (1989) A telomeric sequence in the RNA of tetrahymena telomerase required for telomere repeat synthesis. Nature 337 331-337
    • (1989) Nature , vol.337 , pp. 331-337
    • Greider, C.W.1    Blackburn, E.H.2
  • 46
    • 0025787643 scopus 로고
    • Telomere loss: Mitotic clock or genetic time bomb?
    • Harley CB (1991) Telomere loss: mitotic clock or genetic time bomb? Mutation Research 256 271-282
    • (1991) Mutation Research , vol.256 , pp. 271-282
    • Harley, C.B.1
  • 47
    • 0025279931 scopus 로고
    • Telomeres shorten during ageing of human fibroblasts
    • Harley CB, Futcher AB and Greider CW (1990) Telomeres shorten during ageing of human fibroblasts. Nature 345 458-460
    • (1990) Nature , vol.345 , pp. 458-460
    • Harley, C.B.1    Futcher, A.B.2    Greider, C.W.3
  • 51
    • 0025776523 scopus 로고
    • Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast
    • Heitman J, Movva NR and Hall MN (1991) Targets for cell cycle arrest by the immunosuppressant rapamycin in yeast. Science 253 905-909
    • (1991) Science , vol.253 , pp. 905-909
    • Heitman, J.1    Movva, N.R.2    Hall, M.N.3
  • 52
    • 0030006735 scopus 로고    scopus 로고
    • In situ analysis of changes in telomere size during replicative aging and cell transformation
    • Henderson S, Allsopp R, Spector D, Wang S-S and Harley C (1996) In situ analysis of changes in telomere size during replicative aging and cell transformation. Journal of Cell Biology 134 1-12
    • (1996) Journal of Cell Biology , vol.134 , pp. 1-12
    • Henderson, S.1    Allsopp, R.2    Spector, D.3    Wang, S.-S.4    Harley, C.5
  • 56
    • 0027987170 scopus 로고
    • Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/Cip1, expression in the absence of p53
    • Jiang H, Lin J, Su Z-z, Collart FR, Huberman E and Fisher PB (1994) Induction of differentiation in human promyelocytic HL-60 leukemia cells activates p21, WAF1/Cip1, expression in the absence of p53. Oncogene 9 3397-3406
    • (1994) Oncogene , vol.9 , pp. 3397-3406
    • Jiang, H.1    Lin, J.2    Su, Z.-Z.3    Collart, F.R.4    Huberman, E.5    Fisher, P.B.6
  • 57
    • 0028314952 scopus 로고
    • Cdc25a is a novel phosphatase functioning early in the cell cycle
    • Jinno S, Suto K, Nagata A et al (1994) Cdc25a is a novel phosphatase functioning early in the cell cycle. EMBO Journal 13(7) 1549-1556
    • (1994) EMBO Journal , vol.13 , Issue.7 , pp. 1549-1556
    • Jinno, S.1    Suto, K.2    Nagata, A.3
  • 58
    • 0029061587 scopus 로고
    • Correction of radiation senstivity in ataxia telangectasia cells by a truncated IkB-alpha
    • Jung M, Zhang Y, Lee S and Dritschilo A (1995) Correction of radiation senstivity in ataxia telangectasia cells by a truncated IkB-alpha. Science 268 1619-1621
    • (1995) Science , vol.268 , pp. 1619-1621
    • Jung, M.1    Zhang, Y.2    Lee, S.3    Dritschilo, A.4
  • 59
    • 0028821895 scopus 로고
    • Effects of a recombinant adenovirus expressing WAF1/Cip1 on cell growth, cell cycle and apoptosis
    • Katayose D, Wersto R, Cowan KH and Seth P (1995) Effects of a recombinant adenovirus expressing WAF1/Cip1 on cell growth, cell cycle and apoptosis. Cell Growth and Differentiation. 61207-1212
    • (1995) Cell Growth and Differentiation , vol.6 , pp. 1207-1212
    • Katayose, D.1    Wersto, R.2    Cowan, K.H.3    Seth, P.4
  • 60
    • 0027971222 scopus 로고
    • An essential gene, ESR-1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae
    • Kato R and Ogawa H (1994) An essential gene, ESR-1, is required for mitotic cell growth, DNA repair and meiotic recombination in Saccharomyces cerevisiae. Nucleic Acids Research 23 3104-3112
    • (1994) Nucleic Acids Research , vol.23 , pp. 3104-3112
    • Kato, R.1    Ogawa, H.2
  • 61
    • 0028800996 scopus 로고    scopus 로고
    • PIK-related kinases: DNA repair, recombination and cell cycle checkpoints
    • Keith CT and Schreiber SL (1996) PIK-related kinases: DNA repair, recombination and cell cycle checkpoints. Science 270 50-51
    • (1996) Science , vol.270 , pp. 50-51
    • Keith, C.T.1    Schreiber, S.L.2
  • 62
    • 0028897013 scopus 로고
    • Mutation in the silencing gene SIR4 can delay aging in S cerevisiae
    • Kennedy BK, Austriaco NR Jr, Zhang J and Guarente L (1995) Mutation in the silencing gene SIR4 can delay aging in S cerevisiae. Cell 80 485-496
    • (1995) Cell , vol.80 , pp. 485-496
    • Kennedy, B.K.1    Austriaco N.R., Jr.2    Zhang, J.3    Guarente, L.4
  • 63
    • 0028564951 scopus 로고
    • Specific association of human telomerase activity with immortal cells and cancer
    • Kim NW, Piatyszek MA, Prowse KT et al (1994) Specific association of human telomerase activity with immortal cells and cancer. Science 266 2011-2014
    • (1994) Science , vol.266 , pp. 2011-2014
    • Kim, N.W.1    Piatyszek, M.A.2    Prowse, K.T.3
  • 64
    • 0025029030 scopus 로고
    • Hypervariable ultra-long telomeres in mice
    • Kipling D and Cooke HJ (1990) Hypervariable ultra-long telomeres in mice. Nature 347 400-402
    • (1990) Nature , vol.347 , pp. 400-402
    • Kipling, D.1    Cooke, H.J.2
  • 65
    • 0026849392 scopus 로고
    • Beginning or end? Telomere structure, genetics and biology
    • Kipling D and Cooke HJ (1992) Beginning or end? Telomere structure, genetics and biology. Human Molecular Genetics 1 3-6
    • (1992) Human Molecular Genetics , vol.1 , pp. 3-6
    • Kipling, D.1    Cooke, H.J.2
  • 68
    • 0028924516 scopus 로고
    • Increased p53 protein associated with aging in human diploid fibroblasts
    • Kulju KS and Lehman L (1995) Increased p53 protein associated with aging in human diploid fibroblasts. Experimental Cell Research 21 336-345
    • (1995) Experimental Cell Research , vol.21 , pp. 336-345
    • Kulju, K.S.1    Lehman, L.2
  • 70
    • 0029033695 scopus 로고
    • An in vitro assay for Saccharomyces telomerase requires EST1
    • Lin J-J and Zakian VA (1995) An in vitro assay for Saccharomyces telomerase requires EST1. Cell 81 1127-1135
    • (1995) Cell , vol.81 , pp. 1127-1135
    • Lin, J.-J.1    Zakian, V.A.2
  • 72
    • 0029164707 scopus 로고
    • Cataloging altered gene expression in young and senescent cells using enhanced differential display
    • Linskens MHK, Feng J, Andrews WH et al (1995) Cataloging altered gene expression in young and senescent cells using enhanced differential display. Nucleic Acids Research 23 3244-3251
    • (1995) Nucleic Acids Research , vol.23 , pp. 3244-3251
    • Mhk, L.1    Feng, J.2    Andrews, W.H.3
  • 73
    • 0027269711 scopus 로고
    • Deregulation of cyclins D1 and E and suppression of cdk2 and cdk4 in senescent human fibroblasts
    • Lucibello FC, Sewing A, Brusselbach S, Burger C and Muller R (1993) Deregulation of cyclins D1 and E and suppression of cdk2 and cdk4 in senescent human fibroblasts. Journal of Cell Science 105 123-133
    • (1993) Journal of Cell Science , vol.105 , pp. 123-133
    • Lucibello, F.C.1    Sewing, A.2    Brusselbach, S.3    Burger, C.4    Muller, R.5
  • 74
    • 0024973811 scopus 로고
    • A mutant with defect in telomere elongation leads to senescence in yeast
    • Lundblad V and Szostak JW (1989) A mutant with defect in telomere elongation leads to senescence in yeast. Cell 57 633-643
    • (1989) Cell , vol.57 , pp. 633-643
    • Lundblad, V.1    Szostak, J.W.2
  • 75
    • 0029102354 scopus 로고
    • Runaway telomere elongation caused by telomerase RNA gene mutations
    • McEachem MJ and Blackburn EH (1995) Runaway telomere elongation caused by telomerase RNA gene mutations. Nature 376 403-409
    • (1995) Nature , vol.376 , pp. 403-409
    • McEachem, M.J.1    Blackburn, E.H.2
  • 76
    • 0029746495 scopus 로고    scopus 로고
    • Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase
    • McEachern MJ and Blackburn EH (1996) Cap-prevented recombination between terminal telomeric repeat arrays (telomere CPR) maintains telomeres in Kluyveromyces lactis lacking telomerase. Genes and Development 10 1822-1834
    • (1996) Genes and Development , vol.10 , pp. 1822-1834
    • McEachern, M.J.1    Blackburn, E.H.2
  • 77
    • 0024325562 scopus 로고
    • The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
    • Morin GB (1989) The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats. Cell 59 521-529
    • (1989) Cell , vol.59 , pp. 521-529
    • Morin, G.B.1
  • 78
    • 0029150855 scopus 로고
    • TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1
    • Morrow DM, Tagle DA, Shiloh Y, Collins FS and Hieter P (1995) TEL1, an S. cerevisiae homolog of the human gene mutated in ataxia telangiectasia, is functionally related to the yeast checkpoint gene MEC1. Cell 82 831-840
    • (1995) Cell , vol.82 , pp. 831-840
    • Morrow, D.M.1    Tagle, D.A.2    Shiloh, Y.3    Collins, F.S.4    Hieter, P.5
  • 80
    • 0026703325 scopus 로고
    • Creative blocks: Cell cycle checkpoints and feedback controls
    • Murray AW (1992) Creative blocks: cell cycle checkpoints and feedback controls. Nature 359 599-604
    • (1992) Nature , vol.359 , pp. 599-604
    • Murray, A.W.1
  • 83
    • 0028980925 scopus 로고
    • Chromosome and associations, telomeres and telomerase activity in ataxia telangiectasia cells
    • Pandita TK, Pathak S and Geard CR (1995) Chromosome and associations, telomeres and telomerase activity in ataxia telangiectasia cells. Cytogenetics and Cell Genetics 71 86-93
    • (1995) Cytogenetics and Cell Genetics , vol.71 , pp. 86-93
    • Pandita, T.K.1    Pathak, S.2    Geard, C.R.3
  • 86
    • 0026599596 scopus 로고
    • Transcription factor AP-1 activity is required for initiation of DNA synthesis and is lost during cellular aging
    • Riabowol K, Schiff J and Gilman MZ (1992) Transcription factor AP-1 activity is required for initiation of DNA synthesis and is lost during cellular aging. Proceedings of the National Academy of Sciences of the USA 89 157-161
    • (1992) Proceedings of the National Academy of Sciences of the USA , vol.89 , pp. 157-161
    • Riabowol, K.1    Schiff, J.2    Gilman, M.Z.3
  • 88
    • 0030593033 scopus 로고    scopus 로고
    • Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways
    • Sanchez Y, Desnay BA, Jones WJ, Liu Q, Wang B and Elledge SJ (1996) Regulation of RAD53 by the ATM-like kinases MEC1 and TEL1 in yeast cell cycle checkpoint pathways. Science 271 357-360
    • (1996) Science , vol.271 , pp. 357-360
    • Sanchez, Y.1    Desnay, B.A.2    Jones, W.J.3    Liu, Q.4    Wang, B.5    Elledge, S.J.6
  • 89
    • 0027421043 scopus 로고
    • Loss of a yeast telomere: Arrest, recovery, and chromosome loss
    • Sandell LL and Zakian VA (1993) Loss of a yeast telomere: arrest, recovery, and chromosome loss. Cell 75 729-739
    • (1993) Cell , vol.75 , pp. 729-739
    • Sandell, L.L.1    Zakian, V.A.2
  • 90
    • 0028827312 scopus 로고
    • The complete sequence of the coding region of the ATM gene reveals simlarity to cell cycle regulators in different species
    • Savitsky K, Sfez S, Tagle DA et al (1995) The complete sequence of the coding region of the ATM gene reveals simlarity to cell cycle regulators in different species. Human Molecular Genetics 4 2025-2032
    • (1995) Human Molecular Genetics , vol.4 , pp. 2025-2032
    • Savitsky, K.1    Sfez, S.2    Tagle, D.A.3
  • 93
    • 0026054961 scopus 로고
    • A role for both RB and p53 in the regulation of human cellular senescence
    • Shay JW, Pereira-Smith OM and Wright WE (1991) A role for both RB and p53 in the regulation of human cellular senescence. Experimental Cell Research 196 33-39
    • (1991) Experimental Cell Research , vol.196 , pp. 33-39
    • Shay, J.W.1    Pereira-Smith, O.M.2    Wright, W.E.3
  • 94
    • 0025052004 scopus 로고
    • Repression of c-fos transcription and altered genetic program in senescent human fibroblasts
    • Seshardi T and Campisi J (1990) Repression of c-fos transcription and altered genetic program in senescent human fibroblasts. Science 247 205-209
    • (1990) Science , vol.247 , pp. 205-209
    • Seshardi, T.1    Campisi, J.2
  • 95
    • 0027263711 scopus 로고
    • E6 of human papillomavirus type 16 can overcome the Ml stage of immortalization in human mammary epithelial cells but not in human fibroblasts
    • Shay JW, Wright WE, Brasiskyte D and Van DerHaegen BA (1993) E6 of human papillomavirus type 16 can overcome the Ml stage of immortalization in human mammary epithelial cells but not in human fibroblasts. Oncogene 8 1407-1413
    • (1993) Oncogene , vol.8 , pp. 1407-1413
    • Shay, J.W.1    Wright, W.E.2    Brasiskyte, D.3    Van DerHaegen, B.A.4
  • 97
    • 0027944347 scopus 로고
    • TLC1: Template RNA component of Saccharomyces cerevisiae telomerase
    • Singer MS and Gottschling DE (1994) TLC1: template RNA component of Saccharomyces cerevisiae telomerase. Science 266 404-409
    • (1994) Science , vol.266 , pp. 404-409
    • Singer, M.S.1    Gottschling, D.E.2
  • 98
    • 0030038104 scopus 로고    scopus 로고
    • Replicative senescence: Implications for in vivo aging and tumor suppression
    • Smith JR and Pereira-Smith OM (1996) Replicative senescence: implications for in vivo aging and tumor suppression. Science 273 63-67
    • (1996) Science , vol.273 , pp. 63-67
    • Smith, J.R.1    Pereira-Smith, O.M.2
  • 100
    • 0025150387 scopus 로고
    • Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblasts
    • Stein GH, Beeson M and Gordon L (1990) Failure to phosphorylate the retinoblastoma gene product in senescent human fibroblasts. Science 249 666-669.
    • (1990) Science , vol.249 , pp. 666-669
    • Stein, G.H.1    Beeson, M.2    Gordon, L.3
  • 103
    • 0029019717 scopus 로고
    • Telomerase activity in human liver tissues: Comparison between chronic liver disease and hepatocellular carcinomas
    • Tahara H, Nakanishi T, Kitamoto M et al (1995) Telomerase activity in human liver tissues: comparison between chronic liver disease and hepatocellular carcinomas. Cancer Research 55 2734-2736
    • (1995) Cancer Research , vol.55 , pp. 2734-2736
    • Tahara, H.1    Nakanishi, T.2    Kitamoto, M.3
  • 104
    • 0028946009 scopus 로고
    • Increase in expression level of p21 with increasing division age in both normal and SV-40 transformed human fibroblasts
    • Tahara T, Sato E, Noda A and Ide T (1995) Increase in expression level of p21 with increasing division age in both normal and SV-40 transformed human fibroblasts. Oncogene 10 835-840
    • (1995) Oncogene , vol.10 , pp. 835-840
    • Tahara, T.1    Sato, E.2    Noda, A.3    Ide, T.4
  • 106
    • 0027486732 scopus 로고
    • Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes
    • Vaziri H, Schachter F, Uchida I et al (1993) Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes. American Journal of Human Genetics 52 661-667
    • (1993) American Journal of Human Genetics , vol.52 , pp. 661-667
    • Vaziri, H.1    Schachter, F.2    Uchida, I.3
  • 109
    • 0029127226 scopus 로고
    • Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: A model for senescence?
    • von Zglinicki T, Saretzki G, Docke W and Lotze C (1995) Mild hyperoxia shortens telomeres and inhibits proliferation of fibroblasts: a model for senescence? Experimental Cell Research 220 186-193
    • (1995) Experimental Cell Research , vol.220 , pp. 186-193
    • Von Zglinicki, T.1    Saretzki, G.2    Docke, W.3    Lotze, C.4
  • 110
    • 0029023626 scopus 로고
    • Senescent human fibroblasts resist programmed cell death, and failure to suppress bc!2 is involved
    • Wang E ( 1995) Senescent human fibroblasts resist programmed cell death, and failure to suppress bc!2 is involved. Cancer Research 55 2284-2292
    • (1995) Cancer Research , vol.55 , pp. 2284-2292
    • Wang, E.1
  • 112
    • 0028353634 scopus 로고
    • Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair
    • Weinert TA, Kiser GL and Hartwell LH (1994) Mitotic checkpoint genes in budding yeast and the dependence of mitosis on DNA replication and repair. Genes and Development 8 652-665
    • (1994) Genes and Development , vol.8 , pp. 652-665
    • Weinert, T.A.1    Kiser, G.L.2    Hartwell, L.H.3
  • 113
    • 0028044767 scopus 로고
    • The cellular and molecular biology of skin aging
    • West MD (1994) The cellular and molecular biology of skin aging. Archives of Dermatology 130 87-95
    • (1994) Archives of Dermatology , vol.130 , pp. 87-95
    • West, M.D.1
  • 115
    • 0026682717 scopus 로고
    • Telomere positional effects and the regulation of cellular senescence
    • Wright WE and Shay JW (1992) Telomere positional effects and the regulation of cellular senescence. Trends In Genetics 8 193-197
    • (1992) Trends in Genetics , vol.8 , pp. 193-197
    • Wright, W.E.1    Shay, J.W.2
  • 116
    • 0030004489 scopus 로고    scopus 로고
    • Experimental elongation of telomeres extends the lifespan of immortal x normal cell hybrids
    • Wright WE, Brasiskyte D, Piatyszek MA and Shay JW (1996) Experimental elongation of telomeres extends the lifespan of immortal x normal cell hybrids. EMBO Journal 15 1734-1741
    • (1996) EMBO Journal , vol.15 , pp. 1734-1741
    • Wright, W.E.1    Brasiskyte, D.2    Piatyszek, M.A.3    Shay, J.W.4
  • 117
  • 118
    • 0030068641 scopus 로고    scopus 로고
    • Telomere functions: Lessons from yeast
    • Zakian V (1996) Telomere functions: lessons from yeast. Trends in Cell Biology 6 29-33
    • (1996) Trends in Cell Biology , vol.6 , pp. 29-33
    • Zakian, V.1


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