Effect of chronic hypoxia on K+ channels: Regulation in human pulmonary vascular smooth muscle cells

American Journal of Physiology - Cell Physiology

Volumn 272, Issue 4 41-4, 1997, Pages

  Peng, Wei ^a   Hoidal, John R ^a   Karwande, S V ^b   Farrukh, Imad S ^a,c  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c UNIVERSITY OF UTAH HEALTH SCIENCES CENTER   (United States)

Author keywords

calcium activated potassium channels; guanosine 3',5' cyclic monophosphate dependent protein kinase; guanosine 3',5'cyclic monophosphate; nitric oxide; pulmonary hypertension

Indexed keywords

CALYCULIN A; CHARYBDOTOXIN; CYCLIC AMP; CYCLIC GMP; IBERIOTOXIN; NITRIC OXIDE; POTASSIUM CHANNEL;

ARTICLE; DEPHOSPHORYLATION; DEPOLARIZATION; HUMAN; HUMAN CELL; HYPOXIA; LUNG BLOOD VESSEL; MEMBRANE STEADY POTENTIAL; POTASSIUM TRANSPORT; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PULMONARY HYPERTENSION; REGULATORY MECHANISM; VASCULAR SMOOTH MUSCLE;

EID: 0031005213     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1997.272.4.c1271     Document Type: Article

References (27)

1. Adont, S., B. Raffestin, S. Eddahibi, P. Braquet, and P. E. Chabrier. Loss of endothelium-dependent relaxant activity in the pulmonary circulation of rats exposed to chronic hypoxia. J. Clin. Invest. 87: 155-162, 1991.
2. Archer, S. L., J. M. C. Huang, H. L. Reeve, V. Hampl, S. Tolarova, E. Michelakis, and E. K. Weir. Differential distribution of electrophysiologically distinct myocytes in conduit, and resistance arteries determines their response to nitric oxide and hypoxia. Circ. Res. 78: 431-442, 1996.
3. Bennie, R. E., C. S. Packer, D. R. Powell, N. Jin, and R. A. Rhoades. Biphasic contractile response of pulmonary artery to hypoxia. Am. J. Physiol. 261 (Lung Cell. Mol. Physiol. 5): L156-L163, 1991.
4. Bergofsky, E. H., and S. Holtzman. A study of the mechanisms involved in the pulmonary arterial response to hypoxia. Circ. Res. 20: 506-519, 1967.
5. Butt, E., M. van Bemmelen, L. Fischer, U. Walter, and B. Jastorff. Inhibition of cGMP-dependent protein kinase by (Rp)-guanosine 3′,5′-monophosphorothioates. FEBS Lett. 263: 47-50, 1990.
6. Christopher, O. E., J. T. Reeves, and K. R. Stenark. Pulmonary vasodilation with structurally altered pulmonary vessels and pulmonary hypertension. J. Appl. Physiol. 65: 2459-2467, 1988.
7. Fabiato, A. Computer programs for calculating total from specific free or free from specified total ionic concentrations in aqueous solutions containing multiple metals and ligands. Methods Enzymol. 157: 378-417, 1988.
8. Fried, R., and L. M. Reid. Early recovery from hypoxic pulmonary hypertension: a structural and functional study. J. Appl. Physiol. 57: 1247-1253, 1984.
9. Hamill, O. P., A. Marty, E. Neher, B. Sakmann, and F. J. Sigworth. Improved patch-clamp recording from cells and cell-free membrane patches. Pflügers Arch. 391: 85-100, 1981.
10. 2+-dependent action potentials in small pulmonary arteries of the cat. J. Appl. Physiol. 59: 1389-1393, 1985.
11. + channel blockers on vascular tone in perfused rat lung. Am. Rev. Respir. Dis. 144: 884-887, 1991.
12. Hoshino, Y., H. Obara, M. Kusunoki, Y. Fuji, and S. Iwai. Hypoxic contractile response in isolated human pulmonary artery: role of calcium ions. J. Appl. Physiol. 65: 2468-2474, 1988.
13. Ishihara, H., B. L. Martin, D. L. Brautigan, H. Karaki, H. Ozaki, Y. Kato, N. Fusctani, S. Watabe, K. Hashimoto, D. Uemura, and D. J. Hartshorne. Calyculin A and okadaic acid: inhibitors of protein phosphatase activity. Biochem. Biophys. Res. Commun. 159: 871-877, 1989.
14. Johns, R. A., J. M. Linden, and M. J. Peach. Endothelium-dependent relaxation and cGMP accumulation in rabbit pulmo-nary artery are selectively impaired by moderate hypoxia. Circ. Res.. 65: 1508-1515, 1989.
15. Kobayashi, S., H. Kanade, and M. Nakamura. Cytosolic-free calcium transients in vascular smooth muscle cells: microfluorometric measurements. Science 229: 553-556, 1985.
16. Madden, J. A., C. A. Dawson, and D. R. Harder. Hypoxiainduced activation in small isolated pulmonary arteries from the cat. J. Appl. Physiol. 59: 113-118, 1985.
17. McMurtry, I. F., A. B. Davidson, T. J. Reeves, and R. F. Grover. Inhibition of hypoxic vasoconstriction by calcium antagonists in isolated rat lungs. Circ. Res.. 38: 99-104, 1976.
18. Morganroth, M. L., J. T. Reeves, R. C. Murphy, and N. F. Voelkel. Leukotriene synthesis and receptor blockers block hypoxic pulmonary vasoconstriction. J. Appl. Physiol. 56: 13401346,1984.
19. + channels in human pulmonary vascular smooth muscle cells: role of nitric oxide. J. Appl. Physiol. 81: 1264-1272, 1996.
20. Peng, W., S. V. Karwande, J. R. Hoidal, and I. S. Farrukh. Potassium currents in cultured human pulmonary arterial smooth muscle cells. J. Appl. Physiol. 80: 1187-1196, 1996.
21. Post, J. M., J. R. Hume, S. L. Archer, and E. K. Weir. Direct role for potassium channel inhibition in hypoxic pulmonary vasoconstriction. Am. J. Physiol. 262 (Cell Physiol. 31): C882-C890, 1992.
22. Rounds, S., and I. F. McMurtry. Inhibitors of oxidative ATP production cause transient vasoconstriction and block subsequent pressor responses in rat lungs. Circ. Res.. 48: 393-400, 1981.
23. + current in rat pulmonary artery muscle cells. Am. J. Physiol. 266 (Heart Circ. Physiol. 35): H365-H370, 1994.
24. 2 supports blood flow to hypoxic alveoli in anesthetized dogs. J. Appl. Physiol. 56: 1246-1251, 1984.
25. Suzuki, H., and B. M. Twarog. Membrane properties of smooth muscle cells in pulmonary hypertensive rats. Am. J. Physiol. 242 (Heart Circ. Physiol. 11): H907-H915, 1982.
26. Taha, Z., F. Kiechie, and T. Malinski. Oxidation of nitric oxide by oxygen in biological system by prophyrinic acid sensor. Biochem. Biophys. Res. Commun. 188: 734-739, 1992.
27. Yuan, X.-J., M. L. Tod, L. J. Rubin, and M. P. Blaustein. Contrasting effects of hypoxia on tension in rat pulmonary and mesenteric arteries. Am. J. Physiol. 259 (Heart Circ. Physiol. 28): H281-H289, 1990.