Stability of ondansetron hydrochloride and dexamethasone sodium phosphate in 0.9% sodium chloride injection and in 5% dextrose injection

American Journal of Health-System Pharmacy

Volumn 54, Issue 9, 1997, Pages 1065-1068

  Evrard, Brigitte ^a,b   Ceccato, Attilio ^b   Gaspard, Olivier ^c   Delattre, Luc ^d   Delporte, Jean Pierre ^e  

^a Dept of Pharmaceutical Technology ^*  (Belgium)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c UNIVERSITY OF LIÈGE   (Belgium)

^d School of Pharmacy   (Belgium)

^e ULH

Author keywords

[No Author keywords available]

Indexed keywords

DEXAMETHASONE SODIUM PHOSPHATE; ONDANSETRON; SODIUM CHLORIDE;

DRUG MIXTURE; DRUG STORAGE; EXCIPIENT COMPATIBILITY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; NOTE; PRIORITY JOURNAL;

EID: 0031005188     PISSN: 10792082     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajhp/54.9.1065     Document Type: Note

References (4)

1. Smith DB, Newlands ES, Rustin GJ et al. Comparison of ondansetron and ondansetron plus dexamethasone as antiemetic prophylaxis during cisplatin-containing chemotherapy. Lancet. 1991; 338:487-90.
2. McGuire TR, Narducci WA, Fox JL. Compatibility and stability of ondansetron hydrochloride, dexamethasone, and lorazepam in injectable solutions. Am J Hosp Pharm. 1993; 50: 1410-4.
3. Hagan RL, Mallet MS, Fox JL. Stability of ondansetron hydrochloride and dexamethasone sodium phosphate in infusion bags and syringes for 32 days. Am J Health-Syst Pharm. 1996; 53:1431-5.
4. Leak RE, Woodford JD. Pharmaceutical development of ondansetron tablets. Eur J Cancer Clin Oncol. 1989; 25(suppl 1):S63-6.