Decreased anterior cingulate gyrus metabolic rate in schizophrenia

American Journal of Psychiatry

Volumn 154, Issue 5, 1997, Pages 682-684

  Haznedar, M Mehmet ^b   Buchsbaum, Monte S ^a   Luu, Christina ^b   Hazlett, Erin A ^b   Siegel Jr , Benjamin V ^b   Lohr, James ^b   Wu, Joseph ^b   Haier, Richard J ^b   Bunney Jr , William E ^b  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; BRAIN METABOLISM; CINGULATE GYRUS; CLINICAL ARTICLE; GLUCOSE METABOLISM; HUMAN; MALE; METABOLIC RATE; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; SCHIZOPHRENIA; VISUAL DISCRIMINATION;

EID: 0031004908     PISSN: 0002953X     EISSN: None     Source Type: Journal    
DOI: 10.1176/ajp.154.5.682     Document Type: Article

References (13)

1. Mueser KT, Bellack AS, Douglas MS, Wade JH: Prediction of social skill acquisition in schizophrenic and major affective disorder patients from memory and symptomatology. Psychiatry Res 1991; 37:281-296
2. Olson CR, Musil SY, Goldberg ME: Posterior cingulate cortex and visuospatial cognition, in Neurobiology of Cingulate Cortex and Limbic Thalamus. Edited by Vogt BA, Gabriel M. Boston, Birkhauser, 1993, pp 366-380
3. Benes FM: Neurobiological investigations in cingulate cortex of schizophrenic brain. Schizophr Bull 1993; 19:537-549
4. Andreasen NC, Rezai K, Alliger R, Swayze VW II, Flaum M, Kirchner P, Cohen G, O'Leary DS: Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia: assessment with xenon 133 single-photon emission computed tomography and the Tower of London. Arch Gen Psychiatry 1992; 49:943-958
5. Buchsbaum MS: Schizophrenia: charting the circuits (news). Nature 1995; 378:128-129
6. Tamminga CA, Thaker GK, Buchanan R, Kirkpatrick B, Alphs LD, Chase TN, Carpenter WT: Limbic system abnormalities identified in schizophrenia using positron emission tomography with fluorodeoxyglucose and neocortical alterations with deficit syndrome. Arch Gen Psychiatry 1992; 49:522-530
7. Siegel BV Jr, Buchsbaum MS, Bunney WE Jr, Gottschalk LA, Haier RJ, Lohr JB, Lottenberg S, Najafi A, Nuechterlein KH, Potkin SG, Wu JC: Cortical-striatal-thalamic circuits and brain glucose metabolic activity in 70 unmedicated male schizophrenic patients. Am J Psychiatry 1993; 150:1325-1336
8. Talairach J, Tournoux P: Co-planar Stereotaxic Atlas of the Human Brain. Three-Dimensional Proportional System: An Approach to Cerebral Imaging. Translated by Rayport M. New York, Thieme Medical Publishers, 1988
9. Pardo JV, Fox PT, Raichle ME: Localization of a human system for sustained attention by positron emission tomography. Nature 1991; 349:61-64
10. Corbetta M, Miezin FM, Dobmeyer S, Shulman GL, Petersen SE: Selective and divided attention during visual discriminations of shape, color, and speed. J Neurosci 1991; 11:2383-2402
11. Devinsky O, Morrell MJ, Vogt BA: Contributions of anterior cingulate cortex to behavior. Brain 1995; 118:279-306
12. Wyatt RJ, Karoum F, Casanova MF: Decreased DOPAC in the anterior cingulate cortex of individuals with schizophrenia. Biol Psychiatry 1995; 38:4-12
13. Squires RF, Lajtha A, Saederup E, Palkovits M: Reduced 3H-flumtrazepam binding in cingulate cortex and hippocampus of postmortem schizophrenic brains. Neurochem Res 1993; 18: 219-223