Jak3 activation in human lymphocyte precursor cells

Clinical and Experimental Immunology

Volumn 108, Issue 3, 1997, Pages 552-556

  Sharfe, N ^a   Dadi, H K ^a   O'Shea, J J ^b   Roifman, C M ^a  

^a HOSPITAL FOR SICK CHILDREN   (Canada)

^b NATIONAL INSTITUTE OF ARTHRITIS AND MUSCULOSKELETAL AND SKIN DISEASES   (United States)

Author keywords

IL 7; immunodeficiency; Jak3; pre B; thymocytes

Indexed keywords

PROTEIN TYROSINE KINASE;

ARTICLE; CELL DIFFERENTIATION; COMBINED IMMUNODEFICIENCY; HUMAN; HUMAN CELL; LYMPHOPOIESIS; PRIORITY JOURNAL; PROLYMPHOCYTE; T LYMPHOCYTE; THYMOCYTE;

EID: 0031004666     PISSN: 00099104     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2249.1997.4001304.x     Document Type: Article

References (35)

1. Noguchi M, Yi H, Rosenblatt HM et al. Interleukin-2 receptor γ chain mutation resuls in X-linked severe combined immunodeficiency in humans. Cell 1993; 73:147-57.
2. Puck JM, Deschenes SM, Porter JC et al. The Interleukin-2 receptor γ chain maps to Xq13.1 and is mutated in X-linked severe combined immunodeficiency. SCIDX1. Hum Mol Genet 1993; 2:1099-102.
3. Voss SD, Hong R, Sondel PM. Severe combined immunodeficiency, Interleukin-2 (IL-2), and the IL-2 receptor: experiments of nature continue to point the way. Blood 1994; 83:626-35.
4. Kondo M, Takeshita T, Higuchi M et al. Functional participation of the IL-2 receptor γ chain in IL-7 receptor complexes. Science 1994; 263:1453-4.
5. Kondo M, Takeshita T, Ishii N et al. Sharing of the interleukin-2 (IL-2) receptor γ chain between receptors for IL-2 and IL-4. Science 1993; 262:1874-6.
6. Noguchi M, Nakamura Y, Russell SM et al. Interleukin-2 receptor γ chain: a functional component of the interleukin-7 receptor. Science 1993; 262:1877-80.
7. c chain of the IL2 receptor. Science 1994; 266:1039-42.
8. c chains with Jak1 and Jak3: implications for XSCID and XCID. Science 1994; 266:1042-4.
9. Witthuhn BA, Quelle FW, Silvennoinen O et al. Jak2 associates with the erythropoietin receptor and is tyrosine phosphorylated and activated following stimulation with erythropoeitin. Cell 1993; 74:227-36.
10. Argetsinger LS, Campbell GS, Yang X et al. Identification of Jak2 as a growth hormone receptor associated tyrosine kinase. Cell 1993; 74:237-44.
11. Silvennoinen O, Witthuhn BA, Quelle et al. Structure of the murine Jak2 protein-tyrosine kinase and its role in interleukin 3 signal transduction. Proc Natl Acad Sci USA 1993; 90:8429-33.
12. Wilks AF, Harpur AG, Kurban RR et al. Two novel protein-tyrosine kinases, each with a second phosphotransferase- related catalytic domain, define a new class of protein kinase. Mol Cell Biol 1991; 11:2057-65.
13. Harpur AG, Andres A-C, Ziemiecki A, Aston RR, Wilks AF. Jak2, a third member of the Jak family of protein tyrosine kinases. Oncogene 1992; 7:1347-53.
14. Narazaki M, Witthuhn BA, Yoshida K et al. Activation of Jak2 kinase mediated by the interleukin 6 signal transducer gp130. Proc Natl Acad Sci USA 1994; 91:2285-9.
15. Shaul K, Ziemiecki A, Wilks AF et al. Polypeptide signalling to the nucleus through tyrosine phosphorylation of Jak and Stat proteins. Nature 1993; 366:580-3.
16. Silvennoinen O, Ihle JN, Schlessinger J, Levy DE. Interferon-induced nuclear signalling by Jak protein tyrosine kinases. Nature 1993; 366:583-5.
17. Zhong Z, Wen Z, Darnell JE Jr. Stat3: a STAT family member activated by tyrosine phosphorylation in response to epidermal growth factor and Interleukin 6. Science 1994; 264:95-98.
18. Russell SM, Tayebi N, Nakajima H et al. Mutation of Jak3 in a patient with SCID: essential role of Jak3 in lymphoid development. Science 1995; 270:797-9.
19. Macchi P, Villa A, Gillani S et al. Mutations of Jak-3 gene in patients with autosomal severe combined immune deficiency (SCID). Nature 1995; 377:65-68.
20. Kawamura M, McVicar DW, Johnston JA et al. Molecular cloning of L-Jak, a Janus kinase family protein-tyrosine kinase expressed in natural killer cells and activated leukocytes. Proc Natl Acad Sci USA 1994; 91:6374-8.
21. Rane SG, Reddy EP. Jak3: a novel Jak kinase associated with terminal differentiation of hematopoetic cells. Oncogene 1994; 9:2415-23.
22. Johnston JA, Kawamura M, Kirken R et al. Phosphorylation and activation of the Jak-3 kinase in response to interleukin-2. Nature 1994; 370:151-3.
23. Witthuhn BA, Silvennoinen O, Miura O et al. Involvement of the Jak-3 janus kinase in signalling by Interleukins 2 and 4 in lymphoid and myeloid cells. Nature 1994; 370:153-7.
24. Sharfe N, Dadi HK, Roifman CM. Jak3 proyein tyrosine kinase mediates interleukin-7 induced activation of phosphatidylinositol 3 kinase. Blood 1995; 86:2077-85.
25. Peschon JJ, Morrissey PJ, Grabstein KH et al. Early lymphocyte expansion is severely impaired in interleukin 7 receptor deficient mice. J Exp Med 1994; 180:1955-60.
26. Muegge K, Vila MP, Durum SK. Interleukin-7: a cofactor for V(D)J rearrangement of the T cell receptor b gene. Science 1993; 261:93-95.
27. Schatz DG, Oettlinger MA, Baltimore D. The V(D)J recombination activating gene. Cell 1989; 59:1035-48.
28. Oettinger MA, Schatz DG, Gorka C, Baltimore D. RAG-1 and RAG-2, adjacent genes that synergistically activate V(D)J recombination. Science 1990; 248:1517-23.
29. Mombaerts P, Iacomini J, Johnson RS et al. RAG-1 deficient mice have no mature B and T lymphocytes. Cell 1992; 68:869-77.
30. Shinkai Y, Rathbun G, Lam K-P et al. RAG-2 deficient mice lack mature lymphocytes owing to inability to initiate V(D)J rearrangement. Cell 1992; 68:855-67.
31. Namen AE, Lupton S, Hjerrild K et al. Stimulation of B-cell progenitors by cloned murine interleukin-7. Nature 1988; 333:571-3.
32. Suda T, Okada S, Suda J et al. A stimulatory effect of recombinant murine interleukin 7 (IL-7) on B-cell colony formation and an inhibitory effect of IL-1a. Blood 1989; 74:1936-41.
33. Willerford DM, Chen J, Ferry et al Interleukin-2 receptor a chain regulates the size and content of the peripheral lymphoid compartment. Immunity 1995; 3:521-30.
34. Thomis DC, Gurniak CB, Tivol E, Sharpe AH, Berg LJ. Defects in B lymphocyte maturation and T lymphocyte activation in mice lacking Jak3. Science 1995; 270:794-7.
35. Nosaka T, van Deursen JM, Tripp RA et al. Defective lymphoid development in mice lacking Jak3. Science 1995; 270:800-2.