Increase of chromosomal aberrations induced by ionising radiation in peripheral blood lymphocytes of civil aviation pilots and crew members

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 377, Issue 1, 1997, Pages 89-93

  Romano, Elena ^a   Ferrucci, Luigi ^a   Nicolai, Fabrizio ^a   Derme, Valentina ^a   De Stefano, Gian Franco ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

Author keywords

Chromosomal aberration; Civil aviation pilots and crew members; Ionizing radiation; Lymphocyte; Peripheral blood

Indexed keywords

AIRPLANE CREW; AIRPLANE PILOT; ARTICLE; CHROMOSOME ABERRATION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; IONIZING RADIATION; MAJOR CLINICAL STUDY; MALE; OCCUPATIONAL EXPOSURE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL;

ADULT; AGE FACTORS; AVIATION; CHROMOSOME ABERRATIONS; COSMIC RADIATION; FEMALE; HUMANS; LYMPHOCYTES; MALE; METAPHASE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; RADIATION, IONIZING; RING CHROMOSOMES; SMOKING;

EID: 0031004659     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0027-5107(97)00064-X     Document Type: Article

References (27)

1. Friedberg W., Faulkner D.N., Snyder L., Darden E.B., O'Brian K. Galactic cosmic radiation exposure and associated health risks air carrier crewmembers. Aviat. Space Environ. Med. 60:1989;1104-1108.
2. Friedberg W., Duke F.E., Snyder L., Faultner D.N., O'Brien K., Darden E.B. Jr., Parker D.E. The cosmic radiation environment at air carrier flights altitude and possible associated health risks. Radiat. Prot. Dosim. 48:(1):1993;21-25.
3. Bramlitt E.T. Commercial aviation crewmember radiation doses. Health Phys. 49:(5):1985;945-948.
4. Bagshaw M., Irvine D., Davies D.M. Exposure to cosmic radiation of British Airways flying crew on ultralonghaul routes. Occup. Environ. Med. 53:1996;495-498.
5. Lantos P. The sun and its effects on the terrestrial environment. Radiat. Prot. Dosim. 48:(1):1993;27-32.
6. International Commission on Radiological Protection 1990 (1991) Recommendation of the International Commission on Radiological Protection. ICRP Publication 60, Pergamon Press, Oxford.
7. Goodhead D.T. Biological effects of high energy radiations. Radiat. Prot. Dosim. 48:(1):1993;111-114.
8. Evans H.J., Buckton K.E., Hamilton G.E., Carothers A. Radiation-induced chromosome aberrations in nuclear-dockyard workers. Nature. 277:1979;531-534.
9. Lloyd D.C., Purrot R.J., Reeder J. The incidence of unstable chromosome aberrations in peripheral blood lymphocytes from unirradiated and occupationally exposed people. Mutation Res. 72:1980;523-532.
10. Braselmann H., Schmid E., Bauchinger M. Chromosome aberrations in nuclear power plant workers: the influence of dose accumulation and lymphocyte life-time. Mutation Res. 306:1994;197-202.
11. Natarajan, A.T. (1984) Origin and significance of chromosomal alterations, in: G. Obe (ed.), Mutation in Man, Springer-Verlag, Berlin/Heidelberg/New York/Tokyo.
12. Bender M.A., Awa A.A., Brooks A.L., Evans H.E., Groer P.G., Littlefield L.G., Pereira C., Preston R.J., Wachholz B.W. Current status of cytogenetic procedures to detect and quantify previous exposures to radiation. Mutation Res. 196:1988;103-159.
13. Romm H., Stephan G. Chromosome analysis - a routine method for quantitative radiation dose assessment. Kerntechnik. 55:(4):1990;219-224.
14. Scheid W., Weber J., Traut H., Gabriel H.W. Biological and physical dosimetry after chronic occupational exposure to ionizing radiation: a comparative study. Studia Biophys. 138:1990;205-212.
15. United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR) (1988): Sources, effects and risks of ionizing radiation, 1988 - Report to the general assembly, with annexes, United Nations, New York, 1988.
16. Krain L.S. Aviation, high altitude, cumulative radiation exposure and their associations with cancer. Med. Hypoth. 34:1991;33-40.
17. Irvine D., Davies M. The mortality of British airways pilots, 1966-1989: a proportional mortality study. Aviat. Space Environ. Med. 63:1992;276-279.
18. Band P.R., Spinelli J.J., Ng V.T.Y., Moody J., Callagher R.P. Mortality and cancer incidence in a cohort of commercial airline pilots. Aviat. Space Environ. Med. 61:(4):1990;299-302.
19. Scheid W., Weber J., Traut H., Gabriel H.W. Chromosome aberrations induced in the lymphocytes of pilots and stewardesses. Naturwissenschaften. 80:1993;528-530.
20. Heimers A., Schröder H., Lengfelder E., Schmitz-Feuerhake I. Chromosome aberration analysis in aircrew members. Radiat. Prot. Dosim. 60:(2):1995;171-175.
21. Bender M.A., Preston R.J., Leonard R.C., Pyatt B.E., Gooch P.C., Shelby M.D. Chromosomal aberration and sister chromatid exchange frequencies in peripheral blood lymphocytes of a large human population sample. Mutation Res. 204:1988;421-433.
22. International Atomic Energy Agency (IAEA) (1986) Biological Dosimetry: Chromosomal Aberration Analysis for Dose Assessment, Techn. Rep. 50, Vienna.
23. Doloy M.T., Malarmet J.L., Guedeney G., Bouguignon M., Leroy A., Reillaudou M., Masse R. Use of unstable chromosome aberrations for biological dosimetry after the first postirradiation mitosis. Mutation Res. 125:1991;141-151.
24. Lucas J.N., Tenjin T., Straume T., Pinkel D., Moore II D., Litt M., Gray J.W. Rapid human chromosome aberration analysis using fluorescence in situ hybridization. (Erratum 201). Int. J. Radiat. Biol. 56:1989;35-44.
25. Tucker J.D., Ramsey M.J., Lee D.A., Minkler J.I. Validation of chromosome painting as a biodosimeter in human peripheral lymphocytes following acute exposure to ionizing radiation in vitro. Int. J. Radiat. Biol. 64:1993;27-37.
26. Bauchinger M., Schmid E., Zitselsberger H., Braselmann H., Nahrstedt U. Radiation-induced chromosome aberrations analysed by two-colour fluorescence in situ hybridization with composite whole chromosome-specific DNA probes and pancentromeric DNA probe. Int. J. Radiat. Biol. 64:1993;179-184.
27. Moolgavkar S.H. A two-stage carcinogenesis model for risk assessment. Cell Biol. Toxicol. 5:1989;445-460.