Microinjection of rat GH but not human IGF-I into a defined area of the hypothalamus inhibits endogenous GH secretion in rats

Journal of Endocrinology

Volumn 153, Issue 2, 1997, Pages 283-290

  Minami, S ^a   Suzuki, N ^a   Sugihara, H ^a   Tamura, H ^a   Emoto, N ^a   Wakabayashi, I ^a  

^a NIPPON MEDICAL SCHOOL   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

GROWTH HORMONE; MESSENGER RNA; SOMATOMEDIN C;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEEDBACK SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; MALE; NONHUMAN; PRIORITY JOURNAL; RAT;

EID: 0031004429     PISSN: 00220795     EISSN: None     Source Type: Journal    
DOI: 10.1677/joe.0.1530283     Document Type: Article

References (51)

1. Abe H, Molitch ME, Van Wyk JJ & Underwood LE 1983 Human growth hormone and somatomedin C suppress the spontaneous release of growth hormone in unanesthetized rats. Endocrinology 113 1319-1324.
2. Attardo D & Harvey S 1990 Growth hormone-binding sites in chicken hypothalamus. Journal of Molecular Endocrinology 4 23-29.
3. Bai FL, Yamano M, Shiotani Y, Emson PC, Smith AD, Powell JF & Toyama M 1985 An arcuato-paraventricular and -dorsomedial hypothalamic neuropeptide Y-containing system which lacks noradrcnaline in the rat. Brain Research 331 172-175.
4. Bennett PA, Levy A, Sophokleous S, Robinson ICAF & Lightman SL 1995 Hypothalamic GH receptor gene expression in the rat: effects of altered GH status. Journal of Endocrinology 147 225-234.
5. Berelowitz M, Szabo M, Frohman LA, Firestone S, Chu L & Hintz RL 1981 Somatomedin-C mediates growth hormone negative feedback by effects on both the hypothalamus and the pituitary. Science 212 1279-1281.
6. Burton KA, Kabigting EB, Clifton DK & Steiner RA 1992a Growth hormone receptor messenger ribonucleic acid distribution in the adult male rat brain and its colocalization in hypothalaniic somatostatin neurons. Endocrinology 130 958-963.
7. Burton KA, Steiner RA & Clifton DK 1992b Double-label in situ hybridization confirms that the GRF gene and the GH receptor gene are coexpressed in a subset of neurons in the arcuate nucleus. Proceedings of the 74th Annual Meeting of the Endocrine Society, San Antonio, TX. Abstract no. 1370.
8. Carlsson LMS & Jansson J-O 1990 Endogenous growth hormone (GH) secretion in male rats is synchronized to pulsatile GH infusions given at 3-hour intervals. Endocrinology 126 6-10.
9. Carlsson LMS, Clark RG & Robinson ICAF 1990 Sex difference in growth hormone feedback in the rat. Journal of Endocrinology 126 27-35.
10. Ceda GP, Davis RG, Rosenfeld RG & Hoffman AR 1987 The growth hormone (GH)-releasing hormone (GHRH)-GH-somatomedin axis: evidence for rapid inhibition of GHRH-elicited GH release by insulin-like growth factors I and II. Endocrinology 120 1658-1662.
11. Chan YY, Steiner RA & Clifton DK 1996 Regulation of hypothalamic neuropeptide-Y neurons by growth hormone in the rat. Endocrinology 137 1319-1325.
12. Chihara K, Minamitani N, Kaji H, Arimura A & Fujita T 1981 Intraventricularly injected growth hormone stimulates somatostatin release into rat hypophyseal portal blood. Endocrinology 109 2279-2281.
13. Chomczynski P, Downs TR & Frohman LA 1988 Feedback regulation of growth hormone (GH)-releasing hormone gene expression by GH in rat hypothalamus. Molecular Endocrinology 2 236-241.
14. Clark RG, Chambers G, Lewin J & Robinson ICAF 1986 Automated repetitive microsampling of blood: growth hormone profiles in conscious male rats. Journal of Endocrinology 111 27-35.
15. Clark RG, Carlsson LMS & Robinson ICAF 1988 Growth hormone (GH) secretion in the conscious rat: negative feedback of GH on its own release. Journal of Endocrinology 119 201-209.
16. Conway S, McCann SM & Krulich L 1985 On the mechanism of growth hormone autofeedback regulation: possible role of somatostatin and growth hormone-releasing factor. Endocrinology 117 2284-2292.
17. Daikoku S, Hisano S, Kawano H, Chikamori-Aoyama M, Kagotani Y, Shang R & Chihara K 1988 Ultrastructural evidence for neuronal regulation of growth hormone secretion. Neuroendocrinology 47 405-415.
18. Fletcher TP, Thomas GB, Dunshea FR, Moore LG & Clarke IJ 1995 IGF feedback effects on growth hormone secretion in ewes: evidence for action at the pituitary but not the hypothalamic level. Journal of Endocrinology 144 323-331.
19. Goodyer CG, De Stephano L, Guyda HJ & Posner BI 1984 Effects of insulin-like growth factors on adult male rat pituitary function in tissue culture. Endocrinology 115 1568-1576.
20. Harel Z & Tannenbaum GS 1992 Synergistic interaction between insulin-like growth factors-I and -II in central regulation of pulsatile growth hormone secretion. Endocrinology 131 758-764.
21. Hisano S, Tsuruo Y, Kagotani Y, Daikoku S & Chihara K 1990 Immunohistochemical evidence for synaptic connections between neuropeptide Y-containing axons and periventricular somatostatin neurons in the anterior hypothalamus in rats. Brain Research 520 170-177.
22. Kamegai J, Minami S, Sugihara H, Higuchi H & Wakabayashi I 1994 Growth hormone induces expression of the c-fos gene on hypothalamic neuropeptide-Y and somatostatin neurons in hypophysectomized rats. Endocrinology 135 2765-2771.
23. Kamegai J, Minami S, Sugihara H, Hasegawa O, Higuchi H & Wakabayashi I 1996 Growth hormone receptor gene is expressed in neuropeptide Y neurons in hypothalamic arcuate nucleus of rats. Endocrinology 137 2109-2112.
24. Lanzi R & Tannenbaum GS 1992 Time course and mechanism of growth hormone's negative feedback effect on its own spontaneous release. Endocrinology 130 780-788.
25. McDonald JK, Lumpkin MD, Samson WK & McCann SM 1985 Neuropeptide Y affects secretion of luteinizing hormone and growth hormone in ovariectomized rats. Proceedings of the National Academy of Sciences of the USA 82 561-564.
26. Merchenthaler I, Setalo G, Csontos C, Petrusz P, Flerko B & Negro-Vilar A 1989 Combined retrograde tracing and immunocytochemical identification of luteinizing hormone-releasing hormone- and somatostatin-containing neurons projecting to the median eminence of the rat. Endocrinology 125 2812-2821.
27. Merriam GR & Wachter KW 1982 Algorithms for the study of episodic hormone secretion. American Journal of Physiology 243 E310-E318.
28. Minami S, Kamegai J, Sugihara H, Hasegawa O & Wakabayashi I 1992 Systemic administration of recombinant human growth hormone induces expression of the c-fos gene in the hypothalamic arcuate and periventricular nuclei in hypophysectomized rats. Endocrinology 131 247-253.
29. Minami S, Kamegai J, Hasegawa O, Sugihara H, Okada K & Wakabayashi I 1993 Expression of growth hormone receptor gene m rat hypothalamus. Journal of Neuroendocrinolgy 5 691-696.
30. Monta S, Yamashita S & Melmed S 1987 Insulin-like growth factor I action on rat anterior pituitary cells: effects of intracellular messengers on growth hormone secretion and messenger ribonucleic acid levels. Endocrinology 121 2000-2006.
31. Nakamoto JM, Gertner JM, Press CM, Hintz RL, Rosenfeld RG & Genel M 1986 Suppression of the growth hormone (GH) response to clonidine and GH-releasing hormone by exogenous GH. Journal of Clinical Endocrinology and Metabolism 62 822-826.
32. Okada K, Sugihara H, Minami S & Wakabayashi I 1993 Effect of parenteral administration of selected nutrients and central injection of γ-globulin from antiserum to neuropeptide Y on growth hormone secretory pattern in food-deprived rats. Neuroendocrinology 57 678-686.
33. Paxinos G & Watson C 1986 The Rat Brain in Stereotaxic Coordinates. New York: Academic Press.
34. Plotsky PM & Vale W 1985 Patterns of growth hormone-releasing factor and somatostatin secretion into the hypophyseal-portal circulation of the rat. Science 230 461-463.
35. Rettori V, Milenkovic L, Aguila MC & McCann SM 1990 Physiologically significant effect of neuropeptide Y to suppress growth hormone release by stimulating somatostatin discharge. Endocrinology 126 2296-2301.
36. Robinson ICAF, Carmignac DF & Fairhall KM 1993 Growth hormone (GH) receptors, GH binding protein and GH: an autoregulatory system? Acta Paediatrica 391 (Suppl) 22-28.
37. Rogers KV, Vician L, Steiner RA & Clifton DK 1988 The effect of hypophysectomy and growth hormone administration on pre-prosomatostatin messenger ribonucleic acid in the periventricular nucleus of the rat hypothalamus. Endocrinology 122 586-591.
38. Rosenthal SM, Hulse JA, Kaplan SL & Grumbach MM 1986 Exogenous growth hormone inhibits growth hormone-releasing factor-induced growth hormone secretion in normal men. Journal of Clinical Investigation 77 176-180.
39. Sato M & Frohman LA 1993 Differential effects of central and peripheral administration of growth hormone (GH) and insulin-like growth factor on hypothalamic GH-releasing hormone and somatostatin gene expression in GH-deficient dwarf rats. Endocrinology 133 793-799.
40. Sato M, Chihara K, Kita T, Kashio Y, Okimura Y, Kitajima N & Fujita T 1989 Physiological role of somatostarin-mediated autofeedback regulation for growth hormone: importance of growth hormone in triggering somatostatin release during a trough period of pulsatile growth hormone release in conscious male rats. Neuroendocrinology 50 139-151.
41. Simes JM, Wallace JC & Walton PE 1991 The effects of insulin-like growth factor-I (IGF-I), IGF-II and des(1-3)IGF-I, a potent IGF analogue, on growth hormone and IGF-binding protein secretion from cultured rat anterior pituitary cells. Journal of Endocrinology 130 93-99,
42. Spencer GSG, Bass JJ, Hodgkinson SC, Edgley WHR & Moore LG 1991 Effect of intracerebroventricular injection of IGF-I on circulating growth hormone concentration in the sheep. Domestic Animal Endocrinology 8 155-160.
43. Sugihara H, Minami S & Wakabayashi I 1989 Post-somatostatin rebound secretion of growth hormone is dependent on growth hormone-releasing factor in unrestrained female rats. Journal of Endocrinology 122 583-591.
44. Suzuki N, Okada K, Minami S & Wakabayashi I 1996 Inhibitory effect of neuropeptide Y on growth hormone secretion is mediated by Y1 and Y2 receptor subtypes and abolished after anterolateral deafferentation of the medial basal hypothalamus in rats. Regulatory. Peptides 65 145-151.
45. Szabo M, Butz MR, Banerjee SA, Chikaraishi DM & Frohman LA 1995 Autofeedback suppression of growth hormone (GH) secretion in transgenic mice expressing a human GH reporter targeted by tyrosine hydroxylase 5′-flanking sequences to the hypothalamus. Endocrinology 136 4044-4048.
46. Tannenbaum GS 1980 Evidence for autoregulation of growth hormone secretion via the central nervous system. Endocrinology 107 2117-2120.
47. Tannenbaum GS & Ling N 1984 The interrelationship of growth hormone (GH)-releasing factor and somatostatin in generation of the ultradian rhythm of GH secretion. Endocrinology 115 1952-1957.
48. Tannenbaum GS, Guyda HJ & Posner BI 1983 Insulin-like growth factors: a role in growth hormone negative feedback and body weight regulation via brain. Science 220 77-79.
49. Willoughby JO, Brogan M & Kapoor R 1989 Hypothalamic interconnections of somatostatin and growth hormone releasing factor neurons. Neuroendocrinolgy 50 584-591.
50. Wood TL, Berelowitz M, Gelato MC, Roberts CT, LeRoith D, Millard WL & McKelvy JF 1991 Hormonal regulation of rat hypothalamic neuropeptide mRNAs: effect of hypophysectomy and hormone replacement on growth-hormone-releasing factor, somatostatin and the insulin-like growth factors. Neuroendocrinology 53 298-305.
51. Yamashita S & Melmed S 1986 Insulin-like growth factor I action on rat anterior pituitary cells: suppression of growth hormone secretion and messenger ribonucleic acid levels. Endocrinology 118 176-182.