Sex of parent transmission effect in Tourette's syndrome: Evidence for earlier age at onset in maternally transmitted cases suggests a genomic imprinting effect

Neurology

Volumn 48, Issue 4, 1997, Pages 934-937

  Eapen, Valsamma ^a,b   O'Neill, Jane ^a   Gurling, Hugh M D ^a   Robertson, Mary M ^a  

^a ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^b UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; EXTRACHROMOSOMAL INHERITANCE; FEMALE; GENOME IMPRINTING; GILLES DE LA TOURETTE SYNDROME; HUMAN; MAJOR CLINICAL STUDY; MALE; OBSESSION; ONSET AGE; PHENOTYPE; PRIORITY JOURNAL; RELATIVE; TIC;

EID: 0031004189     PISSN: 00283878     EISSN: None     Source Type: Journal    
DOI: 10.1212/wnl.48.4.934     Document Type: Article

References (32)

1. Surani MAH, Reik W, Allen ND. Transgenes as molecular probes for genomic imprinting. Trends Genet 1988;4:59-62.
2. Hall JG. Genomic imprinting: review and relevance to human diseases. Am J Hum Genet 1990;46:853-857.
3. Knoll JHM, Nicholls RD, Magenis RD, et al. Angelman and Prader-Willi syndromes share a common chromosome 15 deletion but differ in parental origin of the deletion. Am J Med Genet 1989;32:285-290.
4. Dryja TP, Mukai S, Peterson R, et al. Parental origin of mutations of the retinoblastoma gene. Nature 1989;339:556-558.
5. Harper PS, Dyken PR. Early onset dystrophia myotonica: evidence supporting a maternal environmental factor. Lancet 1972;2:53-55.
6. Ridley RM, Frith CD, Crow TM, et al. Anticipation in Huntington's disease is inherited through the male line but may originate in the female line. J Med Genet 1988;25:589-595.
7. Miller M, Hall JG. Possible maternal effect on severity of neurofibromatosis. Lancet 1978;2:1071-1073.
8. Eldridge R. Central neurofibromatosis with bilateral acoustic neuroma. Adv Neurol 1981;29:57-65.
9. Harding AE. Genetic aspects of late onset autosomal dominant cerebellar ataxia. J Med Genet 1981;18:436-441.
10. Ottman R, Annegers JF, Hauser WA, et al. Higher risk of seizures in offsprings of mothers than of fathers with epilepsy. Am J Hum Genet 1988;43:257-264.
11. Zoghbi HY, Pollack MS, Lyons LA, et al. Spinocerebellar ataxia: variable age of onset and linkage to HLA in a large kindred. Ann Neurol 1988;23:580-584.
12. Laird CD. Proposed mechanisms of inheritance and expression of the human Fragile X syndrome of mental retardation. Genetics 1987;117:587-599.
13. Pauls DL, Leckman JF. The inheritance of Gilles de la Tourette syndrome and associated behaviours: evidence for autosomal dominant transmission. N Engl J Med 1986;315: 993-997.
14. Eapen V, Pauls DL, Robertson MM. Evidence for autosomal dominant transmission in Tourette's syndrome. United Kingdom cohort study. Br J Psychiatry 1993;162:593-596.
15. Curtis D, Robertson MM, Gurling HMD. Autosomal dominant gene transmission in a large kindred with Gilles de la Tourette syndrome. Br J Psychiatry 1992;160:845-849.
16. Kurlan R, Eapen V, Stern J, et al. Bilineal expression in Tourette syndrome families. Neurology 1994;44:2336-2342.
17. Leckman JF, Scholomskas D, Thompson WD, Belanger A, Weissman MM. Best estimate of lifetime psychiatric diagnoses: a methodological study. Arch Gen Psychiatry 1982;39: 879-883.
18. Robertson MM, Eapen V. The National Hospital Interview Schedule for the assessment of Gilles de la Tourette Syndrome. Int J Methods Psychiat Res 1996;6:203-226.
19. American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders (3rd edition, revised). Washington, DC: American Psychiatric Association, 1987.
20. Nie NH, Hull CH, Jenkins JG. Statistical package for the social sciences. McGraw-Hill: New York, 1978.
21. Holliday R. The significance of DNA methylation in cellular ageing. In: Woodhead AD, Blacket AD, Hallander A, eds. Molecular biology of ageing. New York: Plenum Press, 1985:269-283.
22. Gal A, Writh B, Kaarriainen H, et al. Childhood manifestation of autosomal dominant polycystic kidney disease. Clin Genet 1989;35:13-19.
23. Harper PS, Dyken PR. Early onset dystrophia myotonica: evidence supporting a maternal environmental factor. Lancet 1972;2:53-55.
24. Leckman JF, Pauls DL, Peterson BS, et al. Pathogenesis of Gilles de la Tourette syndrome. Adv Neurol 1992;58:15-24.
25. Furtado S, Suchowersky O. Investigation of the potential role of genetic imprinting in Gilles de la Tourette syndrome. Am J Med Genet 1994;51:51-54.
26. Lichter DG, Jackson LA, Schachter M. Clinical evidence of genomic imprinting in Tourette's syndrome. Neurology 1995; 45:924-928.
27. Comings DE, Comings BG. Tourette's syndrome and attention deficit disorder with hyperactivity: Are they genetically related? J Am Acad Child Adolesc Psychiatry 1984;23:138-146.
28. Comings DE, Comings BG. A controlled study of Tourette syndrome. I: Attention-deficit disorder, learning disorders, and school problems. Am J Hum Genet 1987;41:701-741.
29. Comings DE, Comings BG. A controlled family history study of Tourette's Syndrome, I: Attention-deficit hyperactivity disorder and learning disorders. J Clin Psychiatry 1990;51:275-280.
30. Pauls DL, Hurst CR, Kruger SD, Leckman JF, Kidd KK, Cohen DJ. Gilles de la Tourette's syndrome and attention deficit disorder with hyperactivity: evidence against a genetic relationship. Arch Gen Psychiatry 1986;43:1177-1179.
31. Pauls DL, Leckman JF, Cohen DJ. Familial relationship between Gilles de la Tourette syndrome, attention deficit disorder, learning disorder, speech disorder and stuttering. J Am Acad Child Adolesc Psychiatry 1993;32:1044-1050.
32. Reik J, Collick A, Norris ML, et al. Genomic imprinting determines methylation of parental alleles in transgenic mice. Nature 1987;328:248-251.