Is resting state HCO3- secretion in frog gastric fundus mucosa, mediated by apical Cl--HCO3- exchange?

Journal of Physiology

Volumn 499, Issue 3, 1997, Pages 763-771

  Caroppo, Rosa ^a   Debellis, Lucantonio ^a   Valenti, Giovanna ^a   Alper, Seth ^b   Frömter, Eberhard ^c   Curci, Silvana ^a  

^a UNIVERSITY OF BARI   (Italy)

^b BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^c GOETHE UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BICARBONATE; CHLORIDE ION; RINGER SOLUTION;

ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL MEMBRANE PERMEABILITY; CELL PH; CONTROLLED STUDY; EPITHELIUM CELL; FROG; IMMUNOHISTOCHEMISTRY; ION EXCHANGE; MEMBRANE TRANSPORT; MICROELECTRODE; NONHUMAN; PRIORITY JOURNAL; STOMACH FUNDUS; STOMACH MUCOSA;

EID: 0031003442     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.1997.sp021967     Document Type: Article

References (23)

1. ALLEN, A., FLEMSTRÖM, G., GARNER, A. & KIVILAAKSO, E. (1993). Gastroduodenal mucosal protection. Physiological Reviews 73, 823-857.
2. ALLEN, A. & GARNER, A. (1980). Mucus and bicarbonate secretion in the stomach and their possible role in mucosal protection. Gut 21, 249-262.
3. ALPER, S. L., STUART-TILLEY, A. K., YANNOUKAKOS, D. & BROWN, D. (1995). AE3 anion exchanger immunolocalization in rodent kidney: evidence for apical and basolateral isoforms. Journal of American Society of Nephrology 6, 372a.
4. BORON, W. F., WAISBREN, S. J., MODLIN, I. M. & GEIBEL, J. P. (1994). Unique permeability barrier of the apical surface of parietal and chief cells in isolated perfused gastric glands. Journal of Experimental Biology 196, 347-360.
5. - activity in surface epithelial cells of frog gastric mucosa. Pflügers Archiv 406, 204-211.
6. CURCI, S., DEBELLIS, L., CAROPPO, R. & FRÖMTER, E. (1994). Model of bicarbonate secretion by resting frog stomach fundus mucosa. I. Transepithelial measurements. Pflügers Archiv 428, 648-654.
7. DEBELLIS, L., IACOVELLI, C., FRÖMTER, E. & CURCI, S. (1994). Model of bicarbonate secretion by resting frog stomach fundus mucosa. II. Role of the oxyntopeptic cells. Pflügers Archiv 428, 655-663.
8. FLEMSTRÖM, G. (1977). Active alkalinization by amphibian gastric fundic mucosa in vitro. American Journal of Physiology 233, E1-12.
9. - transport in frog gastric mucosa. Upsala Journal of Medical Science 85, 303-309.
10. FLEMSTRÖM, G., HÄLLGREN, A., NYLANDER, O., ENGSTRAND, L. & ALLEN, A. (1995). The adherent surface mucus gel prevents stimulation of rat duodenal mucosa by luminal Helicobacter pylori and cholera toxins. Gastroenterology 108, A94.
11. FLEMSTRÖM, G. & SACHS, G. (1975). Ion transport by amphibian antrum in vitro. I. General characteristics. American Journal of Physiology 228, 1188-1198.
12. - secretion in the guinea pig. American Journal of Physiology 234, E535-541.
13. KIVILUOTO, T., MUSTONEN, H., SALO, J. & KIVILAAKSO, E. (1995). Regulation of intracellular pH in isolated Necturus gastric mucosa during short-term exposure to luminal acid. Gastroenterology 108, 999-1004.
14. KONDO, Y. & FRÖMTER, E. (1990). Evidence of chloride/bicarbonate exchange mediating bicarbonate efflux from S3 segments of rabbit renal proximal tubule. Pflügers Archiv 415, 726-733.
15. - activities in rabbit renal collecting ducts. Tohoku Journal of Experimental Medicine 169, 51-58.
16. KOTTRA, G., IACOVELLI, C., CAROPPO, R., CURCI, S., BAKOS, P. & FRÖMTER, E. (1996). Contribution of surface epithelial cells to total conductance of Necturus gastric fundus mucosa. American Journal of Physiology 270, G902-908.
17. -? Journal of Surgical Research 58, 211-217.
18. O'BRIEN, P., ROSEN, S., TRENCIS-BUCK, L. & SILEN, W. (1977). Distribution of carbonic anhydrase within the gastric mucosa. Gastroenterology 72, 870-874.
19. 1 in rabbit parietal, chief, and surface cells. American Journal of Physiology 256, G466-475.
20. STUART-TILLEY, A., SARDET, C., POUYSSEGUR, J., SCHWARTZ, M. A., BROWN, D. & ALPER, S. L. (1994). Immunolocalization of anion exchanger AE2 and cation exchanger NHE-1 in distinct adjacent cells of gastric mucosa. American Journal of Physiology 266, C559-568.
21. TAKEUCHI, K., MERHAV, A. & SILEN, W. (1982). Mechanisms of luminal alkalinization by bullfrog fundic mucosa. American Journal of Physiology 243, G377-388.
22. TAKEUCHI, K., MAGEE, D., CRITCHLOW, J., MATTHEWS, J. & SILEN, W. (1983). Studies of the pH gradient and thickness of frog gastric mucus gel. Gastroenterology 84, 331-340.
23. WAISBREN, S. J., GEIBEL, J. P., MODLIN, I. M. & BORON, W. F. (1994). Unusual permeability properties of gastric gland cells. Nature 368, 332-335.