Maturation decreases ethanol minimum alveolar anesthetic concentration (MAC) more than desflurane MAC in rats

Anesthesia and Analgesia

Volumn 84, Issue 4, 1997, Pages 852-858

  Fang, Zexu ^a   Gong, Diane ^a   Ionescu, Pompiliu ^a   Laster, Michael J ^a   Eger II, Edmond I ^a   Kendig, Joan ^b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL; ALKANOL; DESFLURANE;

ANESTHESIA; ANESTHESIA INDUCTION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; FETUS LUNG MATURATION; HYPOTHESIS; MINIMUM LUNG ALVEOLUS CONCENTRATION; NONHUMAN; PRESSURE MEASUREMENT; PRIORITY JOURNAL; RAT;

AGE FACTORS; ANIMALS; ETHANOL; FEMALE; ISOFLURANE; MALE; PARTIAL PRESSURE; PULMONARY ALVEOLI; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY;

EID: 0031003382     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000539-199704000-00028     Document Type: Article

References (30)

1. Fang ZX, Ionescu P, Chortkoff BS, et al. Anesthetic potencies of n-alkanols: results of additivity studies suggest a mechanism of action similar to that for conventional inhaled anesthetics. Anesth Analg. In press.
2. Taheri S, Halsey MJ, Liu J, et al. What solvent best represents the site of action of inhaled anesthetics in humans, rats and dogs? Anesth Analg 1991;72:627-34.
3. Eger EI II. Partition coefficients of I-653 in human blood, saline, and olive oil. Anesth Analg 1987;66:971-3.
4. Rampil IJ, Lockhart S, Zwass M, et al. Clinical characteristics of desflurane in surgical patients: minimum alveolar concentration. Anesthesiology 1991;74:429-33.
5. Taylor RH, Lerman J. Minimum alveolar concentration of desflurane and hemodynamic responses in neonates, infants, and children. Anesthesiology 1991;75:975-9.
6. Stevens WC, M DW, Gibbons RT, et al. Minimum alveolar concentrations (MAC) of isoflurane with and without nitrous oxide in patients of various ages. Anesthesiology 1975;42:197-200.
7. Gregory GA, Eger EI II, Munson ES. The relationship between age and halothane requirement in man. Anesthesiology 1969;30:488-91.
8. Fisher DM, Zwass MS. MAC of desflurane in 60% nitrous oxide in infants and children. Anesthesiology 1992;76:354-6.
9. Sebel PS, Glass PSA, Fletcher JE, et al. Reduction of the MAC of desflurane with fentanyl. Anesthesiology 1992;76:52-9.
10. Yoshimoto K, Komura S. Monitoring of ethanol levels in the rat nucleus accumbens by brain microdialysis. Alcohol Alcohol 1993;28:171-4.
11. Severinghaus JW. Role of lung factors. In Papper E, Kitz R, eds. Uptake and distribution of anesthetic agents. New York: McGraw-Hill, 1963:59-71.
12. Holmberg H, Schouenborg J. Postnatal development of the nociceptive withdrawal reflexes in the rat: a behavioral and electromyographic study. J Physiol 1996;493:239-52.
13. Loss GE Jr, Seifen E, Kennedy RH, Seifen AB. Aging: effects on minimum alveolar concentration (MAC) for halothane in Fischer-344 rats. Anesth Analg 1989;68:359-62.
14. Cameron CB, Robinson S, Gregory GA. The minimum anesthetic concentration of isoflurane in children. Anesth Analg 1984;63:418-20.
15. Mapleson WW. Effect of age on MAC in humans: a meta-analysis. Br J Anaesth 1996;76:179-85.
16. Overton E. Studien uber die Narkose Zugleich ein Beitrag zur Allgemeinen Pharmakologie. Jena: Verlag von Gustav Fischer, 1901.
17. Meyer HH. Theorie der Alkoholnarkose. Arch Exp Pathol Pharmakol 1899;42:109-18.
18. Saidman LJ, Eger EI II, Munson ES, et al. Minimum alveolar concentrations of methoxyflurane, halothane, ether and cyclopropane in man: correlation, with theories of anesthesia. Anesthesiology 1967;28:994-1002.
19. Hornbein TF, Eger EI II, Winter PM, et al. The minimum alveolar concentration of nitrous oxide in man. Anesth Analg 1982;61:553-6.
20. Eger EI II, Larson CP Jr. Anaesthetic solubility in blood and tissues: values and significance. Br J Anaesth 1964;36:140-9.
21. Tolle TR, Berthele A, Zieglgansberger W, et al. The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal gray. J Neurosci 1993;13:5009-28.
22. 125I]MK-801 binding decrease in rat spinal cord after unilateral hind paw inflammation. Neuroscience 1995;68:159-65.
23. A-receptor subtypes in the spinal cord: an immunohistochemical study. J Neurosci 1996;16:283-97.
24. A receptor subunit mRNAs in rat spinal cord and dorsal root ganglia. J Comp Neurol 1993;338:337-59.
25. Antognini JF, Schwartz K. Exaggerated anesthetic requirements in the preferentially anesthetized brain. Anesthesiology 1993;79:1244-9.
26. Rampil IJ. Anesthetic potency is not altered after hypothermic spinal cord transection in rats. Anesthesiology 1994;80:606-10.
27. Rampil IJ, Mason P, Singh H. Anesthetic potency (MAC) is independent of forebrain structures in the rat. Anesthesiology 1993;78:707-12.
28. Long SK, Smith DA, Siarey RJ, Evans RH. Effect of 6-cyano-2,3-dihydroxy-7-nitro-quinoxaline (CNQX) on dorsal root-, NMDA-, kainate- and quisqualate-mediated depolarization of rat motoneurones in vitro. Br J Pharmacol 1990;100:850-4.
29. Brockmeyer DM, Kendig JJ. Selective effect of ketamine on amino acid-mediated pathways in neonatal rats spinal cord. Br J Anaesth 1995;74:79-84.
30. Feng J, Kendig JJ. Selective effect of alfentanil on nociceptive-related neurotransmission in neonatal rats spinal cord. Br J Anaesth 1995;74:691-6.