Binding of prednisolone and its ester prodrugs in the skin

Pharmaceutical Research

Volumn 14, Issue 2, 1997, Pages 197-202

  Hikima, Tomohiro ^a   Tojo, Kakuji ^a  

^a KYUSHU INSTITUTE OF TECHNOLOGY   (Japan)

Author keywords

Percutaneous absorption; Prednisolone; Prednisolone esters; Skin binding

Indexed keywords

PREDNISOLONE; PREDNISOLONE DERIVATIVE; PRODRUG;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MEMBRANE BINDING; MEMBRANE TRANSPORT; MOUSE; NONHUMAN; NUDE MOUSE; PARTITION COEFFICIENT; PRIORITY JOURNAL; SKIN; SKIN ABSORPTION;

ANIMALS; BIOTRANSFORMATION; CHOLINESTERASE INHIBITORS; ESTERS; FEMALE; ISOFLUROPHATE; MICE; PREDNISOLONE; PRODRUGS; SKIN; SKIN ABSORPTION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 0031002893     PISSN: 07248741     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1012052827872     Document Type: Article

References (15)

1. A. Pannatier, P. Jenner, B. Testa, and J. C. Etter. Drug Metabolism Reviews 8(2):319-343 (1978).
2. P. Liu, W. I. Higuchi, W. Song, T. Kurihara-Bergstrom, and W. R. Good. Pharm. Res. 8:565-872 (1991).
3. E. Menczel, D. Bucks, H. Maibach, and R. Wester. Arch. Dermatol. Res. 275:403-406 (1983).
4. J. R. J. Baker, R. A. Christin, P. Simpson, and A. W. White. Br. J. Dermatol. 96:171-178 (1977).
5. B. Mollgaard, and A. Haelgarrd. Int. J. Pharm. 15:185-197 (1983).
6. T. Hikima, K. Yamada, A. Yamashita, and K. Tojo. Drug Deliv. Syst. 7:453-457 (1992).
7. T. Hikima, K. Yamada and K. Tojo. Proc. 22nd Intern. Symp. Control. Rel. Bioact. Mater., #3144, 1995, p. 720-721.
8. Y. Esumi, Y. Jin, K. Hori, K. Ichige, M. Komuro, H. Kakuo, T. Shindo, A. Kageyu, and K. Sudo. Jpn. Pharmacol Ther. 20:4411-4420 (1992).
9. T. Hikima and K. Tojo. Drug Deliv. Syst. 8:291-295 (1993).
10. T. Hikima and K. Tojo. Yakuzaigaku. 55:122-126 (1995).
11. T. Hikima. Ph. D. thesis, Kyushu Institute of Technology (1996).
12. D. B. Guzek, A. H. Kennedy, S. C. McNeill, E. Wakshull, and R. O. Potts. Pharm. Res. 6:33-39 (1989).
13. M. K. Ghosh and A. K. Mitra. Pharm. Res. 7:251-255 (1990).
14. Y. Esumi, Y. Jin, K. Hori, K. Ichige, M. Komuro, H. Kakuo, T. Shindo, A. Kageyu, and K. Sudo. Jpn. Pharmacol. Ther. 20:151 (4421)-168 (4438) (1992).
15. W. R. Vieth. Oxford University Press, New York, 1988.