A simple and reliable method for delivering small fluid volumes to the brain of a freely moving rat

Journal of Neuroscience Methods

Volumn 72, Issue 1, 1997, Pages 35-38

  Hesse, Gary W ^a   Stellar, James R ^a   Chevrette, Jessica ^a  

^a NORTHEASTERN UNIVERSITY   (United States)

Author keywords

Intracranial injection; Microinjection; Micropump

Indexed keywords

EQUIPMENT; MICROINJECTION; PRIORITY JOURNAL; PUMP; SHORT SURVEY;

EID: 0031002757     PISSN: 01650270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-0270(96)00152-5     Document Type: Article

References (10)

1. Bozarth, M.A. and Wise, R.A. (1980) Electrolytic microinfusion transducer system: an alternative method of intracerebral drug application, J. Neurosci. Methods, 2: 273-275.
2. Goeders, N.B. and Smith, J.E. (1987) Intracranial self-administration methodologies, Neurosci. Biobehav. Rev., 11: 319-329.
3. Hoebel, B.G., Monaco, A.P., Hernandez, L., Aulisi, E.F., Stanley, B.G. and Lenard, L. (1983) Self-injection of amphetamine directly into the brain, Psychopharmacology, 81: 158-163.
4. Myers, R.D. (1971) Methods for chemical stimulation of the brain. In R.D. Myers (Ed.), Methods in Psychobiology, Vol. 1, Academic Press, New York, pp. 247-280.
5. Parada, M.A., Pig de Parada, M. and Hoebel, E.G. (1993) A remote insertion technique for intracerebral microinjections in freely moving animals, J. Neurosci. Methods, 50: 237-241.
6. Parada, M.A., Pig de Parada, M. and Hoebel, B.G. (1994) A new triple-channel swivel for fluid delivery in the range of intracranial (10 nl) and intravenous (100 ml) self-administration volumes and also suitable for microdialysis, J. Neurosci. Methods, 54: 1-8.
7. Stellar, J.R. and Lindenfeld, R. (1994) Intracranial drug self-administration method: improvements to allow reward magnitude estimation, Soc. Neurosci., 20: 369.
8. Swanson, L.W., Perez, V.J. and Sharpe, L.G. (1972) Accurate and reliable intracerebral delivery of minute volumes of drug solutions, J. Appl. Physiol., 33: 247-251.
9. Wirth, P.W., Crowder, W.F. and Bedford, J.A. (1977) A low-force swivel connector for infusing liquids into unrestrained animals, Behav. Res. Methods Instrum., 9: 265-266.
10. Yamamoto, T. Oomura, Y., Nemoto, S., Fujita, I. and Nishino, H. (1985) A new method of drug application using electrolysis of water, Brain Res. Bull., 15: 527-528.