17β-hydroxysteroid dehydrogenase deficiency with minimal virilization and spontaneous reduction of serum androgens to normal female levels

Clinical Endocrinology

Volumn 46, Issue 3, 1997, Pages 369-372

  Duncan, S L B ^a   Page, K B ^b   Rodgers, D A ^b  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

^b ROYAL HALLAMSHIRE HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANDROGEN; ANDROSTENEDIONE; BOLDENONE; ESTROGEN; PRASTERONE SULFATE; TESTOSTERONE; TESTOSTERONE 17BETA DEHYDROGENASE;

AMENORRHEA; ARTICLE; CASE REPORT; ENZYME DEFICIENCY; FEMALE; GONADECTOMY; HIRSUTISM; HUMAN; PRIORITY JOURNAL; SEXUAL DEVELOPMENT;

EID: 0031002223     PISSN: 03000664     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2265.1997.1060920.x     Document Type: Article

References (6)

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2. Davis, S., Di Martino, N.A. & Schneider, G. (1980) 17β-Hydroxysteroid dehydiogenase deficiency in malignant interstitial cell carcinoma of the testis. Journal of Clinical Endocrinology and Metabolism, 51, 1293-1297.
3. Givens, J.R., Wiser, W.L., Summitt, R.L., Kerber, I.J., Andersen, R.N., Pittaway, D.E. & Fish, S.A. (1974) Familial male pseudohermaphroditism without gynecomastia due to deficient testicular 17-ketosteroid reductase activity. New England Journal of Medicine, 291, 938-944.
4. Rosler, A., Belanger A., Labrie F. (1992) Mechanisms of androgen production in male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase deficiency. Journal of Clinical Endocrinology and Metabolism, 75, 773-778.
5. Rosler, A. & Kohn, G. (1983) Male pseudohermaphroditism due to 17β-hydroxysteroid dehydrogenase deficiency: studies on the natural history of the defect and effect of androgens on gender role. Journal of Steroid Biochemistry, 19, 663-674.
6. Wit, J.M., van Hoof, C.O.M., Thijssen, J.H.H. & Van den Brande, J.L. (1988) In vivo and in vitro studies in a 46, XY phenotypically female infant with 17-ketosteroid reductase deficiency. Hormone and Metabolic Research, 20, 367-374.