A prospective randomized study of glutamine-enriched parenteral compared with enteral feeding in postoperative patients

American Journal of Clinical Nutrition

Volumn 65, Issue 4, 1997, Pages 977-983

  Fish, Judith ^b   Sporay, George ^b   Beyer, Karen ^b   Jones, John ^b   Kihara, Todd ^b   Kennedy, Alfred ^b   Apovian, Caroline ^b   Jensen, Gordon L ^a  

^a GEISINGER MEDICAL CENTER   (United States)

^b NONE

Author keywords

amino acids; enteral nutrition; Glutamine; humans; postoperative patients; total parenteral nutrition; TPN; tube feeding

Indexed keywords

GLUTAMINE; NITROGEN;

ADULT; AGED; AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; ARTICLE; CALORIC INTAKE; CLINICAL ARTICLE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; ENERGY EXPENDITURE; FEMALE; HUMAN; MALE; NITROGEN BALANCE; PANCREAS SURGERY; POSTOPERATIVE CARE; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL; STOMACH SURGERY; TOTAL PARENTERAL NUTRITION; TUBE FEEDING;

EID: 0031001940     PISSN: 00029165     EISSN: None     Source Type: Journal    
DOI: 10.1093/ajcn/65.4.977     Document Type: Article

References (29)

1. Lacey JM, Wilmore DW. Is glutamine a conditionally essential amino acid? Nutr Rev 1990;48:297-309.
2. Askanazi J, Carpentier YA, Michelsen CB, et al. Muscle and plasma amino acids following injury. Ann Surg 1990;192:78-85.
3. Bergstrom J, Furst P, Noree LO, et al. Intracellular free amino acid concentration in human muscle tissue. J Appl Physiol 1974;36:393-7.
4. Souba WW, Wilmore DW. Postoperative alteration in arteriovenous exchange of amino acids across the gastrointestinal tract. Surgery 1983;94:342-50.
5. Souba WW. Intestinal glutamine metabolism and nutrition. J Nutr Biochem 1993;4:2-9.
6. Souba WW, Smith RJ, Wilmore DW. Glutamine metabolism by the small intestinal tract. JPEN J Parenter Enterai Nutr 1985;9:608-17.
7. Frisell WR. Synthesis and catabolism of nucleotides. In: Frisell WR, ed. Human biochemistry. New York: Macmillan Co, 1982:292-304.
8. Rennie MJ, Hundal HS, Babi P, et al. Characteristics of a glutamine carrier in skeletal muscle have important consequences for nitrogen loss in injury, infection and chronic disease. Lancet 1986;2:1008-11.
9. Windmueller HG. Glutamine utilization by the small intestine. Adv Enzymol 1982;53:201-37.
10. Ziegler TR, Young LS, Benfell K, et al. Clinical and metabolic efficacy of glutamine supplemental parenteral nutrition after a bone marrow transplantation. A randomized double-blind, controlled study. Ann Intern Med 1992;116:821-8.
11. Ziegler TR, Benfell K, Smith R, et al. Safety and metabolic effects of -Lglutamine administration in humans. JPEN J Parenter Enteral Nutr 1990;14(suppl):137S-46S.
12. Schloerb PR, Amare M. Total parenteral nutrition with glutamine in bone marrow transplantation and other clinical applications (a randomized double-blind study). JPEN J Parenter Enteral Nutr 1993;17: 407-13.
13. Jensen GL, Miller RH, Talabiska DG, Fish J, Gianferante L. A double-blind prospective randomized study of glutamine-enriched compared with standard peptide-based feeding in critically ill patients. Am J Clin Nutr 1996;64:615-21.
14. Teasdale G, Jannett B. Assessment of coma and impaired consciousness. A practical scale. Lancet 1974;2:81-3.
15. Jensen GL, Sporay GS, Whitmire S, Taraszewski R, Reed MJ. Intraoperative placement of the nasoenteric feeding tube: a practical alternative? JPEN J Parenter Enteral Nutr 1995;19:244-7.
16. Slocum RH, Cummings JG. Amino acid analysis of physiological samples. In: Hommes FA, ed. Technique in diagnostic human biochemical genetics. New York: Wiley-Liss, 1991:87-126.
17. Lee P, Slocum B. Amino acid analysis of physiological fluids for clinical uses. Pal Alto, CA: Beckman Instruments, 1986.
18. Konstantinides FN, Boehm KA. Real time, cost-effective method for determining total urinary nitrogen. Clin Chem 1988;34:2518-20.
19. Felig P. Amino acid metabolism in man. Annu Rev Biochem 1975;44:933-55.
20. Marliss EB, Aoki TT, Pozefsky T, et al. Muscle and splanchnic glutamine and glutamate metabolism in postabsorptive and starved man. J Clin Invest 1971;50:814-7.
21. Mathews DE, Marano MA, Campbell RG. Splanchnic bed utilization of glutamine and glutamic acid in humans. Am J Physiol 1993;264:E848-54.
22. Dechelotte P, Darmaun D, Rongier M, et al. Absorption and metabolic effects of enterally administered glutamine in humans. Am J Physiol 1991;260:G677-82.
23. Dominique D, Just B, Messing B, et al. Glutamine metabolism in healthy adult men: response to enteral and intravenous feeding. Am J Clin Nutr 1994;59:1395-402.
24. Peterson VM, Moore EE, Jones TN, et al. Total enteral nutrition versus total parenteral nutrition after major torso injury: attenuation of hepatic protein reprioritization. Surgery 1988;104:199-207.
25. Pearlstone DB, Lee J, Alexander RH, et al. Effect of enteral and parenteral nutrition on amino acid levels in cancer patients. JPEN J Parenter Enteral Nutr 1995;19:204-8.
26. Alverdy JA. Effects of glutamine-supplemented diets on immunology of the gut. JPEN J Parenter Enteral Nutr 1990;14(suppl):109S-13S.
27. Jeevanandam M, Young DH, Ramias L, Schiller WR. Aminoaciduria of severe trauma. Am J Clin Nutr 1989;49:814-22.
28. Harper AE, Miller RH, Block KP. Branch-chain amino acid metabolism. Annu Rev Nutr 1984;4:409-54.
29. Smith RJ. Glutamine metabolism and its physiologic importance. JPEN J Parenter Enteral Nutr 1990;14(suppl):40S-4S.