Simple and efficient conversion of colchicine into deacetylcolchicine

Synthetic Communications

Volumn 27, Issue 2, 1997, Pages 293-296

  Lebeau, Luc ^a   Ducray, Pierre ^a   Mioskowski, Charles ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DEACETYLCOLCHICINE;

ARTICLE; DRUG SYNTHESIS; IN VITRO STUDY; NUCLEAR MAGNETIC RESONANCE; REACTION ANALYSIS;

EID: 0031001325     PISSN: 00397911     EISSN: None     Source Type: Journal    
DOI: 10.1080/00397919708005030     Document Type: Article

References (17)

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13. 3, 200 MHz) 7.54 (s, 1H); 7.17 (d, J = 10.6 Hz, 1H); 6.73 (d. J = 10.6 Hz, 1H); 6.51 (s, 1H); 5.12 (dd, J = 5.8, 11.9 Hz, 1H); 3.94 (s, 3H); 3.90 (s, 3H); 3.87 (s, 3H); 3.63 (s, 3H); 2.70-2.37 (m, 3H); 2.25 (s, 3H); 2.02-1.84 (m, 1H); 1.53 (s, 9H).
14. Flynn, D.L.; Zelle, R.E.; Grieco, P.A. J. Org. Chem 1983, 48, 2424-2426.
15. 3, 200 MHz) : 7.49 (s, 1H); 7.23 (d, J = 10.7 Hz, 1H); 6.79 (d, J = 10.7 Hz, 1H); 6.51 (s, 1H); 5.06 (d, J = 7.6 Hz, 1H); 4.42-4.35 (m, 1H); 3.97 (s, 3H); 3.90 (s, 3H); 3.87 (s, 3H); 3.62 (s, 3H); 2.51-2.16 (m, 3H); 1.72-1.63 (m, 1H); 1.33 (s, 9H).
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