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Volumn 34, Issue 1, 1997, Pages 51-63

Inhibition of human immunodeficiency virus type 1 infection in vitro by combination of delavirdine, zidovudine and didanosine

Author keywords

Delavirdine; Drug combination; HIV 1; Reverse transcriptase inhibitors

Indexed keywords

DELAVIRDINE; DIDANOSINE; RNA DIRECTED DNA POLYMERASE INHIBITOR; ZIDOVUDINE;

EID: 0031000763     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-3542(96)01021-2     Document Type: Article
Times cited : (18)

References (42)
  • 1
    • 0029912274 scopus 로고    scopus 로고
    • Mechanisms of nucleoside analog antiviral activity and resistance during human immunodeficiency virus reverse transcription
    • Arts, E.J. and Wainberg, M.A. (1996) Mechanisms of nucleoside analog antiviral activity and resistance during human immunodeficiency virus reverse transcription. Antimicrob. Agents Chemother. 40 (3), 527-540.
    • (1996) Antimicrob. Agents Chemother. , vol.40 , Issue.3 , pp. 527-540
    • Arts, E.J.1    Wainberg, M.A.2
  • 2
    • 0028331518 scopus 로고
    • Genomic variation of human immunodeficiency virus type 1 (HIV-1): Molecular analyses of HIV-1 in sequential blood samples and various organs obtained at autopsy
    • Ball, J.K., Holmes, E.C., Whitwell, H. and Desselberger, U. (1994) Genomic variation of human immunodeficiency virus type 1 (HIV-1): molecular analyses of HIV-1 in sequential blood samples and various organs obtained at autopsy. J. Gen. Virol. 75, 867-879.
    • (1994) J. Gen. Virol. , vol.75 , pp. 867-879
    • Ball, J.K.1    Holmes, E.C.2    Whitwell, H.3    Desselberger, U.4
  • 3
    • 0027202617 scopus 로고
    • Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2′,5′-bis-0-(tert-butyldimethylsilyl)-3′-spiro-5″- (4″-amino-1″,2″-oxathiole-2″,2″-dioxide)]-β- D-pentofuranosyl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleoside inhibitors
    • Balzarini, J., Karlsson, A., Vandamme, A-M. et al. (1993a) Human immunodeficiency virus type 1 (HIV-1) strains selected for resistance against the HIV-1-specific [2′,5′-bis-0-(tert-butyldimethylsilyl)-3′-spiro-5″- (4″-amino-1″,2″-oxathiole-2″,2″-dioxide)]-β- D-pentofuranosyl (TSAO) nucleoside analogues retain sensitivity to HIV-1-specific nonnucleoside inhibitors. Proc. Natl. Acad. Sci. USA 90, 6952-6956.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 6952-6956
    • Balzarini, J.1    Karlsson, A.2    Vandamme, A.-M.3
  • 4
    • 0027363224 scopus 로고
    • Knocking-out concentrations of HIV-1 specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus
    • Balzarini, J., Karlsson, A., Pérez-Pérez, M-J., Camarasa, M-J. and De Clercq, E. (1993b) Knocking-out concentrations of HIV-1 specific inhibitors completely suppress HIV-1 infection and prevent the emergence of drug-resistant virus. Virology 196, 576-585.
    • (1993) Virology , vol.196 , pp. 576-585
    • Balzarini, J.1    Karlsson, A.2    Pérez-Pérez, M.-J.3    Camarasa, M.-J.4    De Clercq, E.5
  • 6
    • 0028003745 scopus 로고
    • Multiple drug effect analysis with confidence interval
    • Belen'kii, M.S. and Schinazi, R.F. (1994) Multiple drug effect analysis with confidence interval. Antiviral Res. 25, 1-11.
    • (1994) Antiviral Res. , vol.25 , pp. 1-11
    • BeleN'Kii, M.S.1    Schinazi, R.F.2
  • 7
    • 0028331215 scopus 로고
    • Combination therapy for HIV-1 infection
    • Caliendo, A.M. and Hirsch, M.D. (1994) Combination therapy for HIV-1 infection. Clin. Infect. Dis. 18, 516-524.
    • (1994) Clin. Infect. Dis. , vol.18 , pp. 516-524
    • Caliendo, A.M.1    Hirsch, M.D.2
  • 8
    • 0028044916 scopus 로고
    • Bisheteroarylpiperazine reverse transcriptase inhibitor in combination with 3′-azido-3′-deoxythymidine or 2′,3′-dideoxycytidine synergistically inhibits human immunodeficiency virus type 1 replication in vitro
    • Chong, K.T., Pagano, P.J. and Hinshaw, R.R. (1994) Bisheteroarylpiperazine reverse transcriptase inhibitor in combination with 3′-azido-3′-deoxythymidine or 2′,3′-dideoxycytidine synergistically inhibits human immunodeficiency virus type 1 replication in vitro. Antimicrob. Agents Chemother. 38, 288-293.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 288-293
    • Chong, K.T.1    Pagano, P.J.2    Hinshaw, R.R.3
  • 9
    • 0021118703 scopus 로고
    • Quantitative analysis of dose-effect relationships: The combined effects of multiple drugs or enzyme inhibitors
    • Chou, T-C. and Talalay, P. (1984) Quantitative analysis of dose-effect relationships: the combined effects of multiple drugs or enzyme inhibitors. Adv. Enzym. Reg. 22, 27-55.
    • (1984) Adv. Enzym. Reg. , vol.22 , pp. 27-55
    • Chou, T.-C.1    Talalay, P.2
  • 10
    • 0027478561 scopus 로고
    • Use of evolutionary limitations of HIV-1 multidrug resistance to optimize therapy
    • Chow, Y.K., Hirsch, M.S., Merrill, D.P. et al. (1993) Use of evolutionary limitations of HIV-1 multidrug resistance to optimize therapy. Nature 361, 650-654.
    • (1993) Nature , vol.361 , pp. 650-654
    • Chow, Y.K.1    Hirsch, M.S.2    Merrill, D.P.3
  • 11
    • 0343168356 scopus 로고
    • A comparative study of a combination of zidovudine, didanosine, and double-blinded nevirapine versus a combination of zidovudine and didanosine
    • Washington, D.C., Abstract No. 384
    • D'Aquila, R., Hughes, M. and Liou, S-H. (1995) A comparative study of a combination of zidovudine, didanosine, and double-blinded nevirapine versus a combination of zidovudine and didanosine. 2nd Nat. Conf. on Human Retroviruses, Washington, D.C., Abstract No. 384.
    • (1995) 2nd Nat. Conf. on Human Retroviruses
    • D'Aquila, R.1    Hughes, M.2    Liou, S.-H.3
  • 12
    • 3042935797 scopus 로고
    • A randomized phase I/II trial of delavirdine (U-90152S) compared to combination nucleoside therapy in HIV-1 infection
    • Washington, D.C., January 29th-February 2nd, Abstract No. 267
    • Davey, R.T., Chaitt, D.G., Freimuth, W.W., et al. (1995) A randomized phase I/II trial of delavirdine (U-90152S) compared to combination nucleoside therapy in HIV-1 infection. 2nd Nat. Conf. on Human Retroviruses and Related Infections, Washington, D.C., January 29th-February 2nd, Abstract No. 267.
    • (1995) 2nd Nat. Conf. on Human Retroviruses and Related Infections
    • Davey, R.T.1    Chaitt, D.G.2    Freimuth, W.W.3
  • 13
    • 0028120730 scopus 로고
    • HIV resistance to reverse transcriptase inhibitors
    • De Clercq, E. (1994a) HIV resistance to reverse transcriptase inhibitors. Biochem. Pharm. 47, 155-169.
    • (1994) Biochem. Pharm. , vol.47 , pp. 155-169
    • De Clercq, E.1
  • 14
    • 0028325491 scopus 로고
    • Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
    • De Clercq, E. (1994b) Non-nucleoside reverse transcriptase inhibitors (NNRTIs). Exp. Opin. Invest. Drugs 3 (3), 253-271.
    • (1994) Exp. Opin. Invest. Drugs , vol.3 , Issue.3 , pp. 253-271
    • De Clercq, E.1
  • 15
    • 0029871192 scopus 로고    scopus 로고
    • Consensus symposium on combined antiviral therapy
    • de Jong, M.D., Boucher, C.A.B., Galasso, G.J. et al. (1996) Consensus symposium on combined antiviral therapy. Antiviral Res. 29, 5-29.
    • (1996) Antiviral Res. , vol.29 , pp. 5-29
    • De Jong, M.D.1    Boucher, C.A.B.2    Galasso, G.J.3
  • 16
    • 0027178052 scopus 로고
    • U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication
    • Dueweke, T.J., Poppe, S.M., Romero, D.L. et al. (1993) U-90152, a potent inhibitor of human immunodeficiency virus type 1 replication. Antimicrob. Agents Chemother. 37, 1127-1131.
    • (1993) Antimicrob. Agents Chemother. , vol.37 , pp. 1127-1131
    • Dueweke, T.J.1    Poppe, S.M.2    Romero, D.L.3
  • 17
    • 0011726686 scopus 로고
    • Phase II clinical trials of delavirdine mesylate combination therapy
    • Yokohama, Japan, August 7-12, Abstract 512B
    • Freimuth, W.W., Davey, R., Batts, D.H., et al. (1994) Phase II clinical trials of delavirdine mesylate combination therapy. 10th Int. Conf. on AIDS, Yokohama, Japan, August 7-12, Abstract 512B, Vol. 2, p. 59.
    • (1994) 10th Int. Conf. on AIDS , vol.2 , pp. 59
    • Freimuth, W.W.1    Davey, R.2    Batts, D.H.3
  • 18
    • 0012759485 scopus 로고    scopus 로고
    • Delavirdine (DLV) and didanosine (ddI) combination therapy has sustained surrogate marker response in advanced HIV-1 population
    • Washington, D.C., Abstract LB8b
    • Freimuth, W.W., Chuang-Stein, C.J., Greenwald, C.A. et al. (1996a) Delavirdine (DLV) and didanosine (ddI) combination therapy has sustained surrogate marker response in advanced HIV-1 population. 3rd Conf. on Retroviruses and Opportunistic Infections, Washington, D.C., Abstract LB8b.
    • (1996) 3rd Conf. on Retroviruses and Opportunistic Infections
    • Freimuth, W.W.1    Chuang-Stein, C.J.2    Greenwald, C.A.3
  • 19
    • 0011783826 scopus 로고    scopus 로고
    • Delavirdine (DLV) in combination with Zidovudine (ZDV) causes sustained antiviral and immunological effects in HIV-1 infected individuals
    • Washington, D.C., Abstract LB8a
    • Freimuth, W.W., Wathen, L.K., Cox, S.R. et al. (1996b) Delavirdine (DLV) in combination with Zidovudine (ZDV) causes sustained antiviral and immunological effects in HIV-1 infected individuals. 3rd Conf. on Retroviruses and Opportunistic Infections, Washington, D.C., Abstract LB8a.
    • (1996) 3rd Conf. on Retroviruses and Opportunistic Infections
    • Freimuth, W.W.1    Wathen, L.K.2    Cox, S.R.3
  • 20
    • 0024337928 scopus 로고
    • HIV-1 isolates are rapidly evolving quasispecies: Evidence for viral mixtures and preferred nucleotide substitutions
    • Goodenow, M., Huet, T., Saurin, W., Kwok, S., Sninsky, J. and Wain-Hobson, S. (1989) HIV-1 isolates are rapidly evolving quasispecies: evidence for viral mixtures and preferred nucleotide substitutions. J. Acquired Immune Defic. Syndr. 2, 344-352.
    • (1989) J. Acquired Immune Defic. Syndr. , vol.2 , pp. 344-352
    • Goodenow, M.1    Huet, T.2    Saurin, W.3    Kwok, S.4    Sninsky, J.5    Wain-Hobson, S.6
  • 21
    • 0026069628 scopus 로고
    • Phenotypic heterogeneity in a panel of infectious molecular human immunodeficiency virus type 1 clones derived from a single individual
    • Groenink, M., Fouchler, R.A.M., de Goede, R.E.Y., de Wolf, F., Gruters, R.A. and Cuypers, T.M. (1991) Phenotypic heterogeneity in a panel of infectious molecular human immunodeficiency virus type 1 clones derived from a single individual. J. Virol. 65, 1968-1975.
    • (1991) J. Virol. , vol.65 , pp. 1968-1975
    • Groenink, M.1    Fouchler, R.A.M.2    De Goede, R.E.Y.3    De Wolf, F.4    Gruters, R.A.5    Cuypers, T.M.6
  • 23
    • 0027991415 scopus 로고
    • Combination therapy: More effective control of HIV Type 1?
    • Johnson, V.A. (1994) Combination therapy: more effective control of HIV Type 1? AIDS Res. Hum. Retroviruses 10, 907-912.
    • (1994) AIDS Res. Hum. Retroviruses , vol.10 , pp. 907-912
    • Johnson, V.A.1
  • 24
    • 0023214674 scopus 로고
    • Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms
    • Koyanagi, Y., Miles, S., Mitsuyasu, RT., et al. (1987) Dual infection of the central nervous system by AIDS viruses with distinct cellular tropisms. Science 236, 819-822.
    • (1987) Science , vol.236 , pp. 819-822
    • Koyanagi, Y.1    Miles, S.2    Mitsuyasu, R.T.3
  • 25
    • 0039100317 scopus 로고
    • Natural polymorphism of HIV-1 clade B protease gene and the implication for therapy
    • Sardinia, Italy, June 9-11, Abstract 76
    • Kozal, M.J., Shah, N., Yang, R. et al. (1995) Natural polymorphism of HIV-1 clade B protease gene and the implication for therapy. 4th Int. HIV Drug Resistance Workshop, Sardinia, Italy, June 9-11, Abstract 76.
    • (1995) 4th Int. HIV Drug Resistance Workshop
    • Kozal, M.J.1    Shah, N.2    Yang, R.3
  • 26
    • 0026454435 scopus 로고
    • 3′-Azido-3′-deoxythymidine resistance suppressed by a mutation conferring human immunodeficiency virus type 1 resistance to non-nucleoside reverse transcriptase inhibitors
    • Larder, B.A. (1992) 3′-Azido-3′-deoxythymidine resistance suppressed by a mutation conferring human immunodeficiency virus type 1 resistance to non-nucleoside reverse transcriptase inhibitors. Antimicrob. Agents Chemother. 36 (12), 2664-2669.
    • (1992) Antimicrob. Agents Chemother. , vol.36 , Issue.12 , pp. 2664-2669
    • Larder, B.A.1
  • 27
    • 0028349644 scopus 로고
    • Alternating versus continuous drug regimens in combination chemotherapy of human immunodeficiency virus type 1 infection in vitro
    • Mazzulli, T., Ruscone, S., Merrill, D.P., et al. (1994) Alternating versus continuous drug regimens in combination chemotherapy of human immunodeficiency virus type 1 infection in vitro. Antimicrob. Agents Chemother. 38, 656-661.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 656-661
    • Mazzulli, T.1    Ruscone, S.2    Merrill, D.P.3
  • 28
    • 0028855166 scopus 로고
    • Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance
    • Mellors, J.W., Larder, B.A. and Schinazi, R.F. (1995) Mutations in HIV-1 reverse transcriptase and protease associated with drug resistance. Int. Antiviral News 3, 8-12.
    • (1995) Int. Antiviral News , vol.3 , pp. 8-12
    • Mellors, J.W.1    Larder, B.A.2    Schinazi, R.F.3
  • 29
    • 0024469503 scopus 로고
    • Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations
    • Meyerhans, A.E., Cheynler, R., Albert, J. et al. (1989) Temporal fluctuations in HIV quasispecies in vivo are not reflected by sequential HIV isolations. Cell 58, 901-910.
    • (1989) Cell , vol.58 , pp. 901-910
    • Meyerhans, A.E.1    Cheynler, R.2    Albert, J.3
  • 30
    • 0027459081 scopus 로고
    • Quantitation of zidovudine-resistant human immunodeficiency virus type 1 in the blood of treated and untreated patients
    • Mohri, H., Singh, M.K., Ching, W.T.W., Ho, D.D. (1993) Quantitation of zidovudine-resistant human immunodeficiency virus type 1 in the blood of treated and untreated patients. Proc. Natl. Acad. Sci. USA 90, 25-29.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 25-29
    • Mohri, H.1    Singh, M.K.2    Ching, W.T.W.3    Ho, D.D.4
  • 31
    • 0343603825 scopus 로고
    • Safety, immunologic and virologie activity of nevirapine in combination with zidovudine therapy in HIV-infected patients
    • Washington, D.C., Abstract No. 262
    • Murphy, R., Havlir, D., Saag, M.S. et al. (1995) Safety, immunologic and virologie activity of nevirapine in combination with zidovudine therapy in HIV-infected patients. 2nd Nat. Conf. on Human Retroviruses, Washington, D.C., Abstract No. 262.
    • (1995) 2nd Nat. Conf. on Human Retroviruses
    • Murphy, R.1    Havlir, D.2    Saag, M.S.3
  • 32
    • 0028051329 scopus 로고
    • Natural occurrence of drug resistance mutations in the reverse transcriptase of human immunodeficiency virus type 1 isolates
    • Nájera, I., Richman, D.D., Olivares, I. et al. (1994) Natural occurrence of drug resistance mutations in the reverse transcriptase of human immunodeficiency virus type 1 isolates. AIDS Res. Hum. Retroviruses 10, 1479-1488.
    • (1994) AIDS Res. Hum. Retroviruses , vol.10 , pp. 1479-1488
    • Nájera, I.1    Richman, D.D.2    Olivares, I.3
  • 33
    • 0028988479 scopus 로고
    • pol Gene quasispecies of human immunodeficiency virus: Mutations associated with drug resistance in virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy
    • Nájera, I., Holguin, A., Quiñones-Mateu, M.E. et al. (1995) pol Gene quasispecies of human immunodeficiency virus: mutations associated with drug resistance in virus: mutations associated with drug resistance in virus from patients undergoing no drug therapy. J. Virol. 69, 23-31.
    • (1995) J. Virol. , vol.69 , pp. 23-31
    • Nájera, I.1    Holguin, A.2    Quiñones-Mateu, M.E.3
  • 34
    • 0028795712 scopus 로고
    • In vitro inhibition of human immunodeficiency virus type 1 by a combination of delavirdine (U-90152) with protease inhibitor U-75875 or interferon-α
    • Pagano, P.J. and Chong, K.T. (1995) In vitro inhibition of human immunodeficiency virus type 1 by a combination of delavirdine (U-90152) with protease inhibitor U-75875 or interferon-α. J. Inf. Dis. 171, 61-67.
    • (1995) J. Inf. Dis. , vol.171 , pp. 61-67
    • Pagano, P.J.1    Chong, K.T.2
  • 35
    • 0029918470 scopus 로고    scopus 로고
    • The implications of drug resistance for strategies of combination antiviral chemotherapy
    • Richman, D.D. (1996) The implications of drug resistance for strategies of combination antiviral chemotherapy. Antiviral Res. 29, 31-33.
    • (1996) Antiviral Res. , vol.29 , pp. 31-33
    • Richman, D.D.1
  • 36
    • 0028143721 scopus 로고
    • Inhibition of human immunodeficiency virus type 1 replication in cytokine-stimulated monocytes/macrophages by combination therapy
    • Rusconi, S. and Merrill, D.P. (1994) Inhibition of human immunodeficiency virus type 1 replication in cytokine-stimulated monocytes/macrophages by combination therapy. J. Infect. Dis. 170, 1361-1366.
    • (1994) J. Infect. Dis. , vol.170 , pp. 1361-1366
    • Rusconi, S.1    Merrill, D.P.2
  • 37
    • 0028884640 scopus 로고
    • In vitro comparison of selected triple-drug combinations for suppression of HIV-1 replication: The intercompany collaboration protocol
    • St. Clair, M.H., Pennington, K.N., Rooney, J. and Barry, D.W. (1995) In vitro comparison of selected triple-drug combinations for suppression of HIV-1 replication: the intercompany collaboration protocol. J. Acquired Defic. Syndr. Hum. Retrovirol. 10 (Suppl. 2), 583-591.
    • (1995) J. Acquired Defic. Syndr. Hum. Retrovirol. , vol.10 , Issue.2 SUPPL. , pp. 583-591
    • St Clair, M.H.1    Pennington, K.N.2    Rooney, J.3    Barry, D.W.4
  • 38
    • 0342733836 scopus 로고
    • A triple combination study with zidovudine, lamivudine (3TC) and loviride (R89439) in p24 positive HIV-1 infected patients: An interim analysis
    • October 4-7, Orlando, FL
    • Staszewski, S., Miller, V., Rehmet, S. et al. (1994) A triple combination study with zidovudine, lamivudine (3TC) and loviride (R89439) in p24 positive HIV-1 infected patients: an interim analysis. 34th Int. Conf. on Antimicrobial Agents and Chemotherapy, October 4-7, Orlando, FL.
    • (1994) 34th Int. Conf. on Antimicrobial Agents and Chemotherapy
    • Staszewski, S.1    Miller, V.2    Rehmet, S.3
  • 39
    • 0026806436 scopus 로고
    • Prevention of the spread of HIV-1 infection with nonnucleoside reverse transcriptase inhibitors
    • Vasudevachari, M.B., Battista, C., Lane, H.C. et al. (1992) Prevention of the spread of HIV-1 infection with nonnucleoside reverse transcriptase inhibitors. Virology 190, 269-277.
    • (1992) Virology , vol.190 , pp. 269-277
    • Vasudevachari, M.B.1    Battista, C.2    Lane, H.C.3
  • 40
    • 0023230120 scopus 로고
    • Isolation frequency and growth properties of HIV-variants: Multiple simultaneous variants in a patient demonstrated by molecular cloning
    • vonBriesen, H., Becker, W.B., Henko, K. et al. (1987) Isolation frequency and growth properties of HIV-variants: multiple simultaneous variants in a patient demonstrated by molecular cloning. J. Med. Virol. 23, 51-66.
    • (1987) J. Med. Virol. , vol.23 , pp. 51-66
    • Vonbriesen, H.1    Becker, W.B.2    Henko, K.3
  • 41
    • 0029814776 scopus 로고    scopus 로고
    • Validation of a quantitative RNa PCR assay for HIV-1 in human plasma
    • Wathen, L.K., Crampton, D.J., Patel, R.K. et al. (1996) Validation of a quantitative RNA PCR assay for HIV-1 in human plasma. J. Clin. Lab. Analy. 10 (5), 262-268.
    • (1996) J. Clin. Lab. Analy. , vol.10 , Issue.5 , pp. 262-268
    • Wathen, L.K.1    Crampton, D.J.2    Patel, R.K.3
  • 42
    • 0343168352 scopus 로고
    • Rapid HIV-1 turnover in patients receiving combination nevirapine (Nev) therapy
    • October 4-7, Orlando, FL. Abstract No. 164
    • Wei, X., Johnson, V., Taylor, M. et al. (1994) Rapid HIV-1 turnover in patients receiving combination nevirapine (Nev) therapy. 34th Int. Conf. on Antimicrobial Agents and Chemotherapy, October 4-7, Orlando, FL. Abstract No. 164.
    • (1994) 34th Int. Conf. on Antimicrobial Agents and Chemotherapy
    • Wei, X.1    Johnson, V.2    Taylor, M.3


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