In vitro skin penetration characteristics of ethanol in the rabbit, mouse, rat, and human

Journal of Toxicology - Cutaneous and Ocular Toxicology

Volumn 16, Issue 1, 1997, Pages 61-75

  Beskitt, Joyce L ^a,c   Sun, James D ^a,b  

^a UNION CARBIDE CORPORATION   (United States)

^b Chemical Group Technical Center ^*  (United States)

^c PPG INDUSTRIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALCOHOL;

ABSORPTION; ANIMAL EXPERIMENT; ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; MALE; MOUSE; NONHUMAN; RABBIT; RAT; RISK ASSESSMENT; SKIN PENETRATION; TOXICITY TESTING;

ANIMALIA; ORYCTOLAGUS CUNICULUS;

EID: 0030998578     PISSN: 07313829     EISSN: None     Source Type: Journal    
DOI: 10.3109/15569529709048888     Document Type: Article

References (14)

1. R. L. Bronaugh, R. F. Stewart, E. R. Congdon, and A. L. Giles, Methods for in vitro percutaneous absorption. I. Comparison with in vivo results, Toxicol. Appl. Pharmacol. 62: 474-480, 1982.
2. J. M. Holland, J. Y. Kao, and M. J. Whitaker, A multi-sample apparatus for kinetic evaluation of skin penetration in vitro: The influence of viability and metabolic status of the skin, Toxicol. Appl. Pharmacol. 72: 272-280, 1984.
3. S. W. Frantz, D. A. Dittenber, D. L. Eisenbrandt, and P. G. Watanabe, Evaluation of a flow-through in vitro skin penetration chamber method using acetone-deposited organic solids, J. Toxicol. Cut. Ocular Toxicol. 9(4): 277-299, 1990.
4. F. N. Marzulli, D. W. C. Brown, and H. I. Maibach, Techniques for studying skin penetration, Toxicol. Appl. Pharmacol. 3: 76-83, 1969.
5. J. Y. Kao, J. Hall, and J. M. Holland, Quantification of cutaneous toxicity: An in vitro approach using skin organ culture, Toxicol. Appl. Pharmacol. 68: 206-217, 1983.
6. H. Eagle, Amino acid metabolism in mammalian cell culture, Science 130: 432, 1959.
7. E. S. Pearson and H. O. Hartley, Biometrika Tables for Statistics, vol. 1. Cambridge University Press, Cambridge, 1954.
8. P. A. Games, An improved t table for simultaneous control on g contrasts, J. Am. Stat. Assoc. 72(359): 531-534, 1977.
9. R. L. Bronaugh, R. F. Stewart, and E. R. Congdon, Methods for in vitro percutaneous absorption studies. II. Animal models for human skin, Toxicol. Appl. Pharmacol. 62: 481-488, 1982.
10. 1 mice, Hartley guinea pigs, and New Zealand White rabbits, J. Toxicol. Cut. Ocular Toxicol. 10(3): 175-186, 1991.
11. 14C-glutaraldehyde using skin from rats, mice, rabbits, guinea pigs and humans, J. Toxicol. Cut. Ocular Toxicol. 12(4): 349-361, 1993.
12. J. D. Sun, S. W. Frantz, and J. L. Beskitt, In vitro skin penetration of ethylene glycol using excised skin from mice and humans, J. Toxicol. Cut. Ocular Toxicol. 14: 273-286, 1995.
13. J. D. Sun, J. L. Beskitt, M. J. Tallant, and S. W. Frantz, In vitro skin penetration of monoethanolamine and diethanolamine using excised skin from rats, mice, rabbits, and humans, J. Toxicol. Cut. Ocular Toxicol. 15(2): 131-146, 1996.
14. R. L. Bronaugh, R. F. Stewart, and M. Simon, Methods for in vitro percutaneous absorption studies. VII. Use of excised human skin, J. Pharmacol. Sci. 75(11): 1094-1097, 1986.