Enhanced survival of glioma bearing rats following boron neutron capture therapy with blood-brain barrier disruption and intracarotid injection of boromophenylalanine

Journal of Neuro-Oncology

Volumn 33, Issue 1-2, 1997, Pages 59-70

  Yang, Weilian ^a   Barth, Rolf F ^a   Rotaru, Joan H ^a   Moeschberger, Melvin L ^a   Joel, Darrel D ^b   Nawrocky, Marta M ^b   Goodman, Joseph H ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b BROOKHAVEN NATIONAL LABORATORY   (United States)

Author keywords

Boron neutron capture therapy; Boronophenylalanine; Glioma; Osmotic blood brain barrier disruption

Indexed keywords

4 BORONOPHENYLALANINE; BORON DERIVATIVE; MANNITOL; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; CANCER SURVIVAL; CAROTID ARTERY; COMPARATIVE STUDY; CONTROLLED STUDY; DOSE RESPONSE; GLIOMA; GLIOMA CELL; INTRAARTERIAL DRUG ADMINISTRATION; INTRAVENOUS DRUG ADMINISTRATION; MALE; NEUTRON CAPTURE THERAPY; NEUTRON RADIATION; NONHUMAN; RAT; STEREOTAXIC SURGERY; SURVIVAL TIME;

EID: 0030997989     PISSN: 0167594X     EISSN: None     Source Type: Journal    
DOI: 10.1023/a:1005769214899     Document Type: Article

References (62)

1. Kornblith PL, Walker M: Chemotherapy for malignant glioma. J Neurosurg 66: 1-17, 1988
2. Laws ER, Thapar K: Brain tumor. CA Cancer J Clin 43: 263-271, 1993
3. Walsh ARW, Darling JL, Thomas DGT: Cerebral gliomas. In: Kennard C (ed) Recent Advances in Clinical Neurology. Churchill Livingston, Edinburgh 241-268, 1990
4. Hatanaka H: Boron-neutron capture therapy for tumors. In: Karim ABMF, Laws ER Jr (eds) Glioma, Principles and Practice in Neuro-Oncology. Springer-Verlag, Berlin 233-249, 1991
5. Bergland R, Elowitz E, Coderre JA, Joel D, Chadha M: A phase I trial of intravenous boronphenylalanine-fructose complex in patients with glioblastoma multiforme. In: Mishima Y (ed) Cancer Neutron Capture Therapy. Plenum Press, New York, 739-746, 1996
6. Barth RF, Soloway AH, Fairchild RG, Brugger RM: Boron neutron capture therapy of brain tumors: past history, current status and future potential. Cancer Invest 14: 534-550, 1996
7. Hawthorne MF: The role of chemistry in the development of boron neutron capture therapy of cancer. Angew Chem Int Ed Eng 32: 950-984, 1993
8. Hatanaka H, Nakagawa Y: Clinical results of long-survival brain tumor patients who underwent boron neutron capture therapy. Int J Radiat Oncol Biol Phys 28: 1061-1066, 1994
9. Oda Y, Takagaki M, Zhang ZH, Kikuchi H, Kobayashi I, Kanda K: Clinical experience with BNCT for malignant brain tumors. In: Soloway AH, Barth RF, Carpenter DE (eds) Advances in Neutron Capture Therapy. Plenum Press, New York, 689-693, 1993
10. Greig NH: Drug delivery to the brain by blood-brain barrier circumvention and drug modification. In: Neuwelt EA (ed) Implications of the Blood-Brain Barrier and its Manipulation. Plenum Press, New York 311-357, 1994
11. Salcman M, Broadwell RD: The blood-brain barrier. In: Salcman M (ed) Neurobiology of Brain Tumors. Williams & Wilkins, Baltimore 229-249, 1991
12. Bullard DE, Bourdon M, Bigner DD: Comparison of various method for delivering radiolabeled monoclonal antibody to normal rat brain. J Neurosurg 61: 901-911, 1984
13. Neuwelt EA, Barnett PA, Hellström KE, Hellström I, MeCormick CI, Ramsey FL: Effect of blood-brain barrier disruption on intact and fragmented monoclonal antibody localization in intracerebral lung carcinoma xenografts. J Nucl Med 35: 1831-1841, 1994
14. Neuwelt EA, Barnett PA: Blood-brain barrier disruption in the treatment of brain tumor: animal studies. In: Neuwelt EA (ed) Implications of the Blood-brain Barrier and its Manipulation: Clinical Implication, Vol. 2. Plenum Press, New York 107-194, 1989
15. Neuwelt EA, Frenkel EP: The challenge of the blood-brain barrier. In: Neuwelt EA (ed) Implications of the Blood-brain Barrier and its Manipulation. Plenum Press, New York 1-24, 1989
16. Dahlborg SA, Henner WD, Crossen JR, Tableman M, Petrillo A, Braziel R. Neuwelt EA: Non-AIDS primary CNS lymphoma: first example of a durable response in a primary brain tumor using enhanced chemotherapy delivery without cognitive loss and without radiotherapy. Cancer Sc Am 2: 166-174, 1996
17. Neuwelt EA, Howeison J, Frenkel EP, Specht HD, Weigel R, Buchan C, Hill SA: Therapeutic efficacy of multiagent chemotherapy with drug delivery enhancement of blood-brain barrier modification in glioblastoma. Neurosurgery 19: 573-583, 1986
18. Williams PC, Hener WD, Roman-Goldstein S, Dahlborg SA, Brummet RE, Tableman M, Dana B, Neuwelt EA: Toxicity and efficacy of carboplatin and etoposide in conjunction with blood-brain tumor barrier modification in the treatment of intracranial neoplasms. Neurosurgery 37: 17-28, 1995
19. 10B compounds: an overview of basic clinical studies. Nucl Sci Appl 4: 349-359, 1991
20. Mishima Y, Honda C, Ichihashi M, Shiono M, Wadabayashi N, Obara H, Hiratsuka J, Fukuda H, Karashima H, Kanda K, Kobayashi T, Yoshino K: Selective melanoma thermal neutron capture therapy for lymph node metastases. In: Soloway AH, Barth RF, Carpenter DE (eds) Advances in Neutron Capture Therapy. Plenum Press, New York 705-710, 1993
21. Coderre JA, Button TM, Micca PL, Fisher CD, Nawrocky MM, Liu HB: Neutron capture therapy of the 9L rat gliosarcoma using the p-boronophenylalanine-fructose complex. Int J Radiat Oncol Biol Phys 30: 643-652, 1994
22. Saris SC, Solares GR, Wazer DE, Cano G, Kerley SE, Joyce MA, Adelman LS, Harling OK, Madoc JH, Zamenhof RG: Boron neutron capture therapy for murine malignant gliomas. Cancer Res 52: 4672-4677, 1992
23. Matalka KZ, Bailey MQ, Barth RF, Staubus AE, Moeschberger ML, Coderre AJ: Boron neutron capture therapy of a rat glioma using boronophenylalanine as a capture agent. Radiat Res 137: 44-51, 1994
24. Barth RF, Matalka KZ, Bailey MQ, Staubus AE, Soloway AH, Moeschberger ML, Coderre JA, Rofstad EK: A nude rat model for neutron capture therapy of human intracerebral melanoma. Int J Radiat Oncol Biol Phys 28: 1079-1088, 1994
25. Coderre JA, Kalef-Ezra JA, Fairchild RG, Micca PL, Reinstein LE, Glass JD: Boron neutron capture therapy of murine melanoma. Cancer Res 48: 6313-6316, 1988
26. Yang W, Barth R, Carpenter DE, Moeschberger M, Goodman JH: Enhanced delivery of boronophenylalanine by means of intracarotid injection and blood-brain barrier disruption for neutron capture therapy. Neurosurgery 38: 985-992, 1996
27. Gabel D: Radiobiological considerations concerning the development of compounds for boron neutron capture therapy. Strahlentherapie 169: 65-70, 1993
28. Ko L, Koestner A, Wechsler W: Morphological characterization of nitrosourea-induced glioma cell lines and clones. Acta Neuropathol 51: 23-31, 1980
29. Clendenon NR, Barth RF, Gordon WA, Goodman JH, Alam F, Staubus AE, Boesel CP, Yates AJ, Moeschberger ML, Fairchild RG, Kalef-Ezra JA: Boron neutron capture therapy of a rat glioma. Neurosurgery 26: 47-55, 1990
30. Bullard DE, Saris SC, Bigner DD: Carotid artery injections in 40- to 90-g Fischer rats: technical note and evaluation of blood flow by various injection techniques. Neurosurgery 14: 406-411, 1984
31. Schuster JM, Friedman HS, Archer GE, Fuchs HE, McLendon RE, Colvin OM, Bigner DD: Intraarterial therapy of human glioma xenografts in athymic rats using 4-hydro-peroxy-cyclpphosphamide. Cancer Res 53: 2338-2343, 1993
32. Yoshino K, Suzuki A, Mori Y, Kanihana H, Honda C, Mishima Y, Kobayashi T, Kanda K: Improvement of solution of p-boronophenylalanine by complex formation with monosaccharides. Strahlentherapie 165: 127-129, 1989
33. Barth RF, Adams DM, Soloway AH, Mechetner EB, Alam F, Anisuzzaman AKM: Determination of boron in tissues and cells using direct-current plasma atomic emission spectroscopy. Anal Chem 63: 890-893, 1991
34. Coderre JA, Joel DD, Micca PL, Nawrocky MM, Slatkin DN: Control of intracerebral gliosarcomas in rats by boron neutron capture therapy with p-boronophenylalanine. Radiat Res 129: 290-296, 1992
35. Joel DD, Fairchild RG, Laissue JA, Saraf SK, Kalef-Ezra JA, Slatkin DN: Boron neutron capture therapy of intracerebral rat gliosarcoma. Proc Natl Acad Sci USA 87: 9808-9812, 1990
36. Slatkin DN, Kalaf-Ezra JA, Saraf SK, Joel DD: Neutron beam design, development and performance for neutron capture therapy. In: Harling OA, Bernard JA, Zamenhof (eds) Basic Life Science, Vol. 54. Plenum Press, New York 317-320, 1990
37. Gabel D, Fairchild RG, Borner HG, Larsson B: The relative biological effectiveness in V79 Chinese hamster cells of neutron capture reaction in boron and nitrogen. Radiat Res 98: 307-316, 1984
38. 7Li irradiation of the brain vasculature. Proc Natl Acad Sci USA 85: 4020-4024, 1988
39. Fairchild RG, Kalef-Ezra JA, Fiarman S, Wielopolski L, Hanz J, Mussolino S, Wheeler F: Optimization of an epithermal beam for NCT at Brookhaven Medical Research Reactor (BMRR). Strahlenther Onkol 165: 215-217, 1989
40. Barth RF, Yang W, Rotaru JH, Moeschberger ML, Joel DD, Nawrocky MM, Goodman JH, Soloway AH: Boron neutron capture therapy of brain tumors: Enhanced survival following intracarotid injection of either socium borocaptate or boronophenylalanine with or without blood-brain barrier disruption. Cancer Res 57: 1129-1136, 1997
41. Gahbauer RA, Fairchild RG, Goodman JH, Blue TE: RBE in normal tissue studies. In: Gabel D, Moss R (eds) Boron Neutron Capture Therapy: Toward Clinical Trials of Glioma Treatment. Plenum Press, New York 123-128, 1992
42. Kaneko S, Allen NJ, Clendenon NR, Kartha M: Treatment schedule of combination using radiation and ACNU in the experimental brain tumors. Neurol Med Chir 23: 849-855, 1983
43. Kaneko S, Clendenon NR, Kartha M: Experimental study in a rat brain tumor by combined treatment with cis-DDP and irradiation. Neurol Med Chir (Tokyo) 23: 917-923, 1983
44. Tzeng JJ, Barth RF, Orosz CG, James SM: Phenotype and functional activity of tumor-infiltrating lymphocytes isolated from immunogenic and nonimmunogenic rat brain tumor. Cancer Res 51: 2373-2378, 1991
45. Pardridge WM: Transport of small molecules through the blood-brain barrier: biology and methodology. Adv Drug Delivery Rev 15: 5-36, 1995
46. Bullard DE, Bigner SH, Bigner DD: Comparison of intravenous versus intracarotid therapy with 1,3-bis(2-chloroethyl)-1-nitrosourea in a rat brain tumor model. Cancer Res 45: 5240-5245, 1985
47. Fenstermacher CD: Intra-arterial infusion of drugs and hyperosmotic solutions as a way of enhancing CNS chemotherapy. Cancer Treat Rep 65: 27-37, 1981
48. 14C-BCNU in the squirrel monkey. J Neurosurg 48: 587-593, 1978
49. Fenstermacher CD, Cowles AL: Theoretic limitation of intracarotid infusion in brain tumor chemotherapy. Cancer Treat Rep 61: 519-526, 1977
50. Greenberg HS, Ensminger WD, Chandler WF, Layton PO, Junck L, Knake J, Vine AK: Intra-artery BCNU chemotherapy for treatment of malignant gliomas of the central nervous system. J Neurosurg 61: 423-429, 1984
51. Newton HB, Page MA, Junck L, Greenberg HS: Intra-arterial cisplatin for the treatment of malignant glioma. J Neurosurg 7: 39-45, 1989
52. Theron J, Villemure JD, Worthington C, Tyler JL: Superselective intracerebral chemotherapy of malignant tumors with BCNU. Neuroradiology 28: 118-125, 1986
53. Saris SC, Blasberg RG, Carson RE, DeVroom HL, Lutz R, Dedrick RL, Pettigrew K, Chang R, Doppman J, Wright DC, Herscovitch P, Oldfield EH: Intravascular streaming during carotid artery infusions. J Neurosurg 74: 763-772, 1991
54. Lahann T, Sills C, Hematillake G, Dymock T, Daniell G: Cardiovascular toxicities associated with intravenous administration of p-boronophenylalanine formulations. In: Soloway AH, Barth RF, Carpenter DE (eds) Advances in Neutron Capture Therapy. Plenum Press, New York 513-517, 1993
55. Jain RK: Barriers to drug delivery in solid tumors. Scientific American 271: 58-65, 1994
56. Groothuis DR, Fischer JM, Vick NA, Bigner DD: Comparative permeability of different glioma models to horseradish peroxidase. Cancer Treat Rep 65: 13-18, 1981
57. Gummerlock MK, Neuwelt EA: Chemotherapy of brain tumors: Innovative approaches. In: Morantz RG, Walsh JW, Dekker M (eds) Handbook of Brain Tumors. Plenum Press, New York 763-778, 1993
58. Miyagami M, Tsubokawa T, Tazoe M, Kagawa Y: Intra-arterial ACNU chemotherapy employing 20% mannitol osmotic blood-brain barrier disruption for malignant brain tumor. Neurol Med Chir (Tokyo) 30: 582-590, 1990
59. Yang W, Barth RF, Rotaru J, Carpenter DE, Goodman JH: Enhanced survival of F98 glioma bearing rats following neutron capture therapy with either sodium borocaptate or boronophenylalanine and osmotic blood-brain barrier disruption. Anticancer Res 15: 5A: 1658, 1995
60. Yang W, Barth RF, Rotaru JH, Joel DD, Nawrocky MM, Moeschberger ML, Goodman JH, Soloway AF: Beuron neutron capture therapy of brain tumors: Enhanced survival following intracarotid injection of sodium borocaptate with or without blood-brain barrier disruption. Int J Radiation Biol Phys 37: 663-672, 1997
61. Inamura T, Nomura T, Bartus RT, Black KL: Intracarotid infusion of RMP-7, a bradykinin analogue: a method for selective drug delivery to brain tumors. J Neurosurg 81: 752-758, 1994
62. Nomura T, Inamura T, Black KL: Intracarotid infusion of bradykinin selectively increases blood-tumor permeability in 9L and C6 brain tumors. Brain Res 659: 62-66, 1994