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Volumn 120, Issue 2, 1997, Pages 119-132

Kupffer cells from halothane-exposed guinea pigs carry trifluoroacetylated protein adducts

Author keywords

Antigen presenting cell; Halothane (2 bromo 2 chloro 1,1,1 trifluoroethane); Hepatotoxicity; Immunochemistry; Kupffer cell; Trifluoroacetylated adduct

Indexed keywords

HALOTHANE;

EID: 0030997811     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(97)03649-4     Document Type: Article
Times cited : (15)

References (40)
  • 1
    • 0029156662 scopus 로고
    • Processing of endoplasmic reticulum luminal antigens associated with halothane hepatitis in rat hepatocytes
    • Amouzadeh, H.R. and Pohl, L.R. (1995) Processing of endoplasmic reticulum luminal antigens associated with halothane hepatitis in rat hepatocytes. Hepatology 22, 936-943.
    • (1995) Hepatology , vol.22 , pp. 936-943
    • Amouzadeh, H.R.1    Pohl, L.R.2
  • 2
    • 0017263223 scopus 로고
    • Halothane-induced liver damage: An analysis of material reported to the Swedish Adverse Drug Reaction Committee 1966-1973
    • Bottinger, L., Dalen, E. and Hallen, B. (1976) Halothane-induced liver damage: an analysis of material reported to the Swedish Adverse Drug Reaction Committee 1966-1973. Acta. Anaesthesiol. Scand. 20, 40-46.
    • (1976) Acta. Anaesthesiol. Scand. , vol.20 , pp. 40-46
    • Bottinger, L.1    Dalen, E.2    Hallen, B.3
  • 3
    • 0027056699 scopus 로고
    • Liver cell heterogeneity: Functions of non-parenchymal cells
    • Bouwens, L., De Bleser, P., Vanderkerken, K., Geerts, B. and Wisse, E. (1993) Liver cell heterogeneity: functions of non-parenchymal cells. Enzyme 46, 155-168.
    • (1993) Enzyme , vol.46 , pp. 155-168
    • Bouwens, L.1    De Bleser, P.2    Vanderkerken, K.3    Geerts, B.4    Wisse, E.5
  • 4
    • 0028324336 scopus 로고
    • Glutathione-S-transferase is a target for covalent modification by a halothane reactive intermediate in the guinea pig liver
    • Brown, A.P. and Gandolfi, A.J. (1994) Glutathione-S-transferase is a target for covalent modification by a halothane reactive intermediate in the guinea pig liver. Toxicology 89, 35-47.
    • (1994) Toxicology , vol.89 , pp. 35-47
    • Brown, A.P.1    Gandolfi, A.J.2
  • 5
    • 0025877439 scopus 로고
    • Generation and detection of neoantigens in guinea pig liver slices incubated with halothane
    • Brown, A.P., Hastings, K. and Gandolfi, A.J. (1991) Generation and detection of neoantigens in guinea pig liver slices incubated with halothane. Int. J. Immunopharmacol. 13, 429-435.
    • (1991) Int. J. Immunopharmacol. , vol.13 , pp. 429-435
    • Brown, A.P.1    Hastings, K.2    Gandolfi, A.J.3
  • 7
    • 0026092349 scopus 로고
    • Halothane metabolism: Kupffer cells carry and partially process trifluoroacetylated protein adducts
    • Christen, U., Burgin, M. and Gut, J. (1991) Halothane metabolism: Kupffer cells carry and partially process trifluoroacetylated protein adducts. Biochem. Biophys. Res. Commun. 175, 256-262.
    • (1991) Biochem. Biophys. Res. Commun. , vol.175 , pp. 256-262
    • Christen, U.1    Burgin, M.2    Gut, J.3
  • 8
    • 0007670815 scopus 로고
    • Mechanisms of anesthetic hepatotoxicity
    • Mosby-Year Book Inc., New York
    • Clarke, J., Lind, R.C. and Gandolfi, A.J. (1993) Mechanisms of anesthetic hepatotoxicity. In: Advances in Anesthesia, Vol. 10, Mosby-Year Book Inc., New York, pp. 219-246.
    • (1993) Advances in Anesthesia , vol.10 , pp. 219-246
    • Clarke, J.1    Lind, R.C.2    Gandolfi, A.J.3
  • 9
    • 0029160166 scopus 로고
    • Halogenated anesthetics form liver adducts and antigens that cross-react with halothane-induced antibodies
    • Clarke, J., Thomas, C., Chen, M., Hastings, K. and Gandolfi, A.J. (1995) Halogenated anesthetics form liver adducts and antigens that cross-react with halothane-induced antibodies. Int. Arch. Allergy Immunol. 108, 24-32.
    • (1995) Int. Arch. Allergy Immunol. , vol.108 , pp. 24-32
    • Clarke, J.1    Thomas, C.2    Chen, M.3    Hastings, K.4    Gandolfi, A.J.5
  • 10
    • 0242632553 scopus 로고
    • Hepatic lipoprotein and cholesterol metabolism
    • D. Zakim and T.D. Boyer (Eds), WB Saunders Company, Philadelphia
    • Cooper, A.D. (1982) Hepatic lipoprotein and cholesterol metabolism. In: D. Zakim and T.D. Boyer (Eds), Hepatotoxicity, WB Saunders Company, Philadelphia, pp. 109-137.
    • (1982) Hepatotoxicity , pp. 109-137
    • Cooper, A.D.1
  • 11
    • 0023259982 scopus 로고
    • Identification and characterization of liver nonparenchymal cells by flow cytometry
    • Doolittle, M., Bohman, R., Durstenfeld, A. and Cascarano, J. (1987) Identification and characterization of liver nonparenchymal cells by flow cytometry. Hepatology 7, 696-703.
    • (1987) Hepatology , vol.7 , pp. 696-703
    • Doolittle, M.1    Bohman, R.2    Durstenfeld, A.3    Cascarano, J.4
  • 12
    • 0029052495 scopus 로고
    • The lipoic acid containing components of the 2-oxoacid dehydrogenase complexes mimic trifluoroacetylated proteins and are autoantigens associated with halothane hepatitis
    • Frey, N., Christen, U., Jeno, P., Yeaman, S.J., Shimomura, Y., Kenna, J.G., Gandolfi, A.J., Ranek, L. and Gut, J. (1995) The lipoic acid containing components of the 2-oxoacid dehydrogenase complexes mimic trifluoroacetylated proteins and are autoantigens associated with halothane hepatitis. Chem. Res. Toxicol. 8, 736-746.
    • (1995) Chem. Res. Toxicol. , vol.8 , pp. 736-746
    • Frey, N.1    Christen, U.2    Jeno, P.3    Yeaman, S.J.4    Shimomura, Y.5    Kenna, J.G.6    Gandolfi, A.J.7    Ranek, L.8    Gut, J.9
  • 13
    • 0029417116 scopus 로고
    • Immunochemical detection of protein adducts in cultured human hepatocytes exposed to diclofenac
    • Gil, M.L., Ramirez, M.C., Terencio, M.C. and Castell, J.V. (1995) Immunochemical detection of protein adducts in cultured human hepatocytes exposed to diclofenac. Biochim. Biophys. Acta 1272, 140-146.
    • (1995) Biochim. Biophys. Acta , vol.1272 , pp. 140-146
    • Gil, M.L.1    Ramirez, M.C.2    Terencio, M.C.3    Castell, J.V.4
  • 14
    • 0025261405 scopus 로고
    • Characterization of molecular species of liver microsomal carboxylesterases of several animal species and humans
    • Hosokawa, M., Maki, T. and Satoh, T. (1989) Characterization of molecular species of liver microsomal carboxylesterases of several animal species and humans. Arch. Biochem. Biophys. 277, 219-227.
    • (1989) Arch. Biochem. Biophys. , vol.277 , pp. 219-227
    • Hosokawa, M.1    Maki, T.2    Satoh, T.3
  • 15
    • 0025114375 scopus 로고
    • Use of structural alterations in the synthesis of halothane metabolite antigens to mimic halothane-induced immunogen
    • Hubbard, A.K., Levy, J.P., Roth, T.P. and Gandolfi, A.J. (1990) Use of structural alterations in the synthesis of halothane metabolite antigens to mimic halothane-induced immunogen. Drug Chem. Toxicol. 13, 93-112.
    • (1990) Drug Chem. Toxicol. , vol.13 , pp. 93-112
    • Hubbard, A.K.1    Levy, J.P.2    Roth, T.P.3    Gandolfi, A.J.4
  • 16
    • 0015334559 scopus 로고
    • Hepatic necrosis produced by repeated administration of halothane to guinea pigs
    • Hughes, H.C. and Lang, C.M. (1972) Hepatic necrosis produced by repeated administration of halothane to guinea pigs. Anesthesiology 36, 466-471.
    • (1972) Anesthesiology , vol.36 , pp. 466-471
    • Hughes, H.C.1    Lang, C.M.2
  • 17
    • 0027933983 scopus 로고
    • Lymph node cell proliferation assay in guinea pigs for the assessment of sensitizing potentials of chemical compounds
    • Kashima, R., Okada, J. and Ikeda, Y. (1994) Lymph node cell proliferation assay in guinea pigs for the assessment of sensitizing potentials of chemical compounds. Food Chem. Toxicol. 32, 831-836.
    • (1994) Food Chem. Toxicol. , vol.32 , pp. 831-836
    • Kashima, R.1    Okada, J.2    Ikeda, Y.3
  • 18
    • 0023253196 scopus 로고
    • Identification by immunoblotting of three halothane-induced liver microsomal polypeptide antigens recognized by antibodies in sera from patients with halothane-associated hepatitis
    • Kenna, J.G., Neuberger, J. and Williams, R. (1987) Identification by immunoblotting of three halothane-induced liver microsomal polypeptide antigens recognized by antibodies in sera from patients with halothane-associated hepatitis. J. Pharmacol. Exp. Ther. 242, 733-740.
    • (1987) J. Pharmacol. Exp. Ther. , vol.242 , pp. 733-740
    • Kenna, J.G.1    Neuberger, J.2    Williams, R.3
  • 19
    • 0024267822 scopus 로고
    • Evidence for expression in human liver of halothane-induced neoantigens recognized by antibodies in sera from patients with halothane hepatitis
    • Kenna, J., Neuberger, J. and Williams, R. (1988a) Evidence for expression in human liver of halothane-induced neoantigens recognized by antibodies in sera from patients with halothane hepatitis. Hepatology 8, 1635-1641.
    • (1988) Hepatology , vol.8 , pp. 1635-1641
    • Kenna, J.1    Neuberger, J.2    Williams, R.3
  • 20
    • 0023898070 scopus 로고
    • Metabolic basis for a drug hypersensitivity: Antibodies in sera from patients with halothane hepatitis recognize liver neoantigens that contain the trifluoroacetyl group derived from halothane
    • Kenna, J.G., Satoh, H., Christ, D.D. and Pohl, L.R. (1988b) Metabolic basis for a drug hypersensitivity: antibodies in sera from patients with halothane hepatitis recognize liver neoantigens that contain the trifluoroacetyl group derived from halothane. J. Pharmacol. Exp. Ther. 245, 1103-1109.
    • (1988) J. Pharmacol. Exp. Ther. , vol.245 , pp. 1103-1109
    • Kenna, J.G.1    Satoh, H.2    Christ, D.D.3    Pohl, L.R.4
  • 21
    • 0017063550 scopus 로고
    • Separation of Kupffer and endothelial cells of the rat liver by centrifugal elutriation
    • Knook, D. and Sleyster, E. (1976) Separation of Kupffer and endothelial cells of the rat liver by centrifugal elutriation. Exp. Cell Res. 99, 444-449.
    • (1976) Exp. Cell Res. , vol.99 , pp. 444-449
    • Knook, D.1    Sleyster, E.2
  • 22
    • 0026005872 scopus 로고
    • Identification and induction of cytochrome P450 2E1 in rat Kupffer cells
    • Koop, D., Chernosky, A. and Brass, E. (1991) Identification and induction of cytochrome P450 2E1 in rat Kupffer cells. J. Pharmacol. Exp. Ther. 258, 1072-1076.
    • (1991) J. Pharmacol. Exp. Ther. , vol.258 , pp. 1072-1076
    • Koop, D.1    Chernosky, A.2    Brass, E.3
  • 23
    • 0024515268 scopus 로고
    • The role of oxidative biotransformation of halothane in the guinea pig model of halothane-associated hepatotoxicity
    • Lind, R.C. and Gandolfi, A.J. (1989) The role of oxidative biotransformation of halothane in the guinea pig model of halothane-associated hepatotoxicity. Anesthesiology 70, 649-653.
    • (1989) Anesthesiology , vol.70 , pp. 649-653
    • Lind, R.C.1    Gandolfi, A.J.2
  • 24
    • 0024378701 scopus 로고
    • Age and gender influence halothane-associated hepatotoxicity in strain 13 guinea pigs
    • Lind, R.C., Gandolfi, A.J. and Hall, P.M. (1989) Age and gender influence halothane-associated hepatotoxicity in strain 13 guinea pigs. Anesthesiology 71, 878-884.
    • (1989) Anesthesiology , vol.71 , pp. 878-884
    • Lind, R.C.1    Gandolfi, A.J.2    Hall, P.M.3
  • 25
    • 0026561390 scopus 로고
    • Subanesthetic halothane is hepatotoxic in the guinea pig
    • Lind, R.C., Gandolfi, A.J. and Hall, P.M. (1992) Subanesthetic halothane is hepatotoxic in the guinea pig. Anesth. Analg. 74, 559-563.
    • (1992) Anesth. Analg. , vol.74 , pp. 559-563
    • Lind, R.C.1    Gandolfi, A.J.2    Hall, P.M.3
  • 26
    • 0028076189 scopus 로고
    • A model for fatal halothane hepatitis in the guinea pig
    • Lind, R.C., Gandolfi, A.J. and Hall, P.M. (1994) A model for fatal halothane hepatitis in the guinea pig. Anesthesiology 81, 478-487.
    • (1994) Anesthesiology , vol.81 , pp. 478-487
    • Lind, R.C.1    Gandolfi, A.J.2    Hall, P.M.3
  • 27
    • 0027685774 scopus 로고
    • Halothane hepatitis patients have serum antibodies that react with protein disulfide isomerase
    • Martin, J.L., Kenna, J.G., Martin, B.M., Thomassen, D., Reed, G.F. and Pohl, L.R. (1993) Halothane hepatitis patients have serum antibodies that react with protein disulfide isomerase. Hepatology 18, 858-863.
    • (1993) Hepatology , vol.18 , pp. 858-863
    • Martin, J.L.1    Kenna, J.G.2    Martin, B.M.3    Thomassen, D.4    Reed, G.F.5    Pohl, L.R.6
  • 28
    • 0018689336 scopus 로고
    • An animal model of halothane hepatotoxicity: Roles of enzyme induction and hypoxia
    • McLain, G.E., Sipes, I.G. and Brown, B.R. (1979) An animal model of halothane hepatotoxicity: roles of enzyme induction and hypoxia. Anesthesiology 51, 321-326.
    • (1979) Anesthesiology , vol.51 , pp. 321-326
    • McLain, G.E.1    Sipes, I.G.2    Brown, B.R.3
  • 29
    • 0027973490 scopus 로고
    • Heterogeneity of Kupffer cells and splenic, alveolar, and peritoneal macrophages for the production of TNF, IL-1, and IL-6
    • Ogle, C.K., Wu, J., Mao, X., Szczur, K., Alexander, J.W. and Ogle, J.D. (1994) Heterogeneity of Kupffer cells and splenic, alveolar, and peritoneal macrophages for the production of TNF, IL-1, and IL-6. Inflammation 18, 511-523.
    • (1994) Inflammation , vol.18 , pp. 511-523
    • Ogle, C.K.1    Wu, J.2    Mao, X.3    Szczur, K.4    Alexander, J.W.5    Ogle, J.D.6
  • 30
    • 0027241426 scopus 로고
    • Mechanisms generating functionally heterogeneous macrophage: Chaos revisited
    • Rutherford, M.S., Witsell, A. and Schook, L.B. (1993) Mechanisms generating functionally heterogeneous macrophage: chaos revisited. J. Leukocyte Biol. 53, 602-618.
    • (1993) J. Leukocyte Biol. , vol.53 , pp. 602-618
    • Rutherford, M.S.1    Witsell, A.2    Schook, L.B.3
  • 31
    • 0023551082 scopus 로고
    • Generation of halothane-induced immune response in a guinea pig model of halothane hepatitis
    • Siadat-Pajouh, M., Hubbard, A., Roth, T. and Gandolfi, A.J. (1987) Generation of halothane-induced immune response in a guinea pig model of halothane hepatitis. Anesth. Analg. 66, 1209-1214.
    • (1987) Anesth. Analg. , vol.66 , pp. 1209-1214
    • Siadat-Pajouh, M.1    Hubbard, A.2    Roth, T.3    Gandolfi, A.J.4
  • 32
    • 0027742271 scopus 로고
    • The biology of macrophages: I. General principles and properties
    • Siljelid, R. and Eskeland, T. (1993) The biology of macrophages: I. General principles and properties. Eur. J. Haematol. 51, 267-275.
    • (1993) Eur. J. Haematol. , vol.51 , pp. 267-275
    • Siljelid, R.1    Eskeland, T.2
  • 33
    • 84991119207 scopus 로고
    • Kupffer cell overload induces intercellular adhesion molecule-1 expression on hepatocytes in genetic hemochromatosis
    • Stal, P., Broome, U., Scheynius, A., Befrits, R. and Hultcrantz, R. (1995) Kupffer cell overload induces intercellular adhesion molecule-1 expression on hepatocytes in genetic hemochromatosis. Hepatology 21, 1308-1316.
    • (1995) Hepatology , vol.21 , pp. 1308-1316
    • Stal, P.1    Broome, U.2    Scheynius, A.3    Befrits, R.4    Hultcrantz, R.5
  • 34
    • 0025178593 scopus 로고
    • Monoclonal antibodies to rat Kupffer cells: Anti-KCA-1 distinguishes Kupffer cells from other macrophages
    • Sugihara, S., Martin, S., Hsuing, C., Maruiwa, M., Bloch, K., Moscicki, R. and Bhan, A. (1990) Monoclonal antibodies to rat Kupffer cells: Anti-KCA-1 distinguishes Kupffer cells from other macrophages. Am. J. Pathol. 136, 345-355.
    • (1990) Am. J. Pathol. , vol.136 , pp. 345-355
    • Sugihara, S.1    Martin, S.2    Hsuing, C.3    Maruiwa, M.4    Bloch, K.5    Moscicki, R.6    Bhan, A.7
  • 35
    • 0025100726 scopus 로고
    • The role of a stress protein in the development of a drug-induced allergic response
    • Thomassen, D., Martin, B.M., Martin, J.L., Pumford, N.R. and Pohl, L.R. (1989) The role of a stress protein in the development of a drug-induced allergic response. Eur. J. Pharmacol. 183, 1138-1139.
    • (1989) Eur. J. Pharmacol. , vol.183 , pp. 1138-1139
    • Thomassen, D.1    Martin, B.M.2    Martin, J.L.3    Pumford, N.R.4    Pohl, L.R.5
  • 36
  • 37
    • 0018827758 scopus 로고
    • Antibodies to the surface of halothane-altered rabbit hepatocytes in patients with severe halothane-associated hepatitis
    • Vergani, D., Mieli-Vergani, G. and Alberti, A. (1980) Antibodies to the surface of halothane-altered rabbit hepatocytes in patients with severe halothane-associated hepatitis. N. Engl. J. Med. 303, 66-71.
    • (1980) N. Engl. J. Med. , vol.303 , pp. 66-71
    • Vergani, D.1    Mieli-Vergani, G.2    Alberti, A.3
  • 38
    • 0028587558 scopus 로고
    • Macrophages are a major source of acetaldehyde in circulating acetaldehyde-albumin complexes formed after exposure of mice to ethanol
    • Wickramasinghe, S.N., Mawas, F., Hasan, R., Brown, I.N. and Goldin, R.D. (1994) Macrophages are a major source of acetaldehyde in circulating acetaldehyde-albumin complexes formed after exposure of mice to ethanol. Alcohol. Clin. Exp. Res. 18, 1463-1467.
    • (1994) Alcohol. Clin. Exp. Res. , vol.18 , pp. 1463-1467
    • Wickramasinghe, S.N.1    Mawas, F.2    Hasan, R.3    Brown, I.N.4    Goldin, R.D.5
  • 39
    • 0029032186 scopus 로고
    • Processing of complex antigens and simple hapten-like molecules by epidermal Langerhans cells
    • Woods, G.M., Henderson, K.G., Qu, M. and Muller, H.K. (1995) Processing of complex antigens and simple hapten-like molecules by epidermal Langerhans cells. J. Leukocyte Biol. 57, 891-896.
    • (1995) J. Leukocyte Biol. , vol.57 , pp. 891-896
    • Woods, G.M.1    Henderson, K.G.2    Qu, M.3    Muller, H.K.4


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