Opposing effects of phorbol esters on transmitter release and calcium currents at frog motor nerve endings

Journal of Physiology

Volumn 501, Issue 1, 1997, Pages 41-48

  Redman, R S ^a   Searl, T J ^a   Hirsh, J K ^a   Silinsky, E M ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLCHOLINE; CALCIUM CHANNEL; CALCIUM ION; PHORBOL DIBUTYRATE; PHORBOL ESTER; CADMIUM; PHORBOL 13 ACETATE 12 MYRISTATE; PROTEIN KINASE C; VOLTAGE GATED CALCIUM CHANNEL;

ACETYLCHOLINE RELEASE; ARTICLE; CALCIUM CURRENT; ELECTROPHYSIOLOGY; ENDPLATE POTENTIAL; EXTRACELLULAR CALCIUM; FROG; MOTOR NERVE; NERVE ENDING; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; ANIMAL TISSUE; CHANNEL GATING; CONTROLLED STUDY; NEUROMUSCULAR SYNAPSE; RANA PIPIENS;

ACETYLCHOLINE; ANIMALS; CALCIUM CHANNEL BLOCKERS; CALCIUM CHANNELS; ELECTROPHYSIOLOGY; ENZYME ACTIVATION; MOTOR ENDPLATE; MOTOR NEURONS; NERVE ENDINGS; NEUROTRANSMITTER AGENTS; PHORBOL 12,13-DIBUTYRATE; PHORBOL ESTERS; PHORBOLS; POTASSIUM CHANNEL BLOCKERS; PROTEIN KINASE C; RANA PIPIENS;

EID: 0030997788     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1469-7793.1997.041bo.x     Document Type: Article

References (28)

1. AHMED, S., MARUYAMA, I. N., KOZMA, R., LEE, J., BRENNER, S. & LIM, L. (1992). The Caenorhabditis elegans unc-13 gene product is a high affinity phorbol ester receptor. Biochemical Journal 287, 995-999.
2. AKERS, R. F., LOVINGER, D. M., COLLEY, P. A., LINDEN, D. J. & ROUTTENBERG, A. (1986). Translocation of protein kinase C activity may mediate hippocampal long-term potentiation. Science 231, 587-589.
3. ANDERSON, A. J., HARVEY, A. L., ROWAN, E. G. & STRONG, P. N. (1988). Effects of charybdotoxin, a blocker of calcium-activated potassium channels, on motor nerve terminals. British Journal of Pharmacology 95, 1329-1335.
4. 2 domain proteins. Journal of Biological Chemistry 270, 25273-25280.
5. CAMPENOT, R. B., DRAKER, D. D. & SENGER, D. L. (1994). Evidence that protein kinase C activities involved in regulating neurite growth are localized to distal neurites. Journal of Neurochemistry 63, 868-878.
6. DEKKER, L. V., DE GRAAN, P. N. E., GISPEN, W. H. (1991). Transmitter release target of regulation by protein kinase C? Progress in Brain Research 89, 209-233.
7. DOERNER, D., PITLER, T. A. & ALGER, B. E. (1988). Protein kinase C activators block specific calcium and potassium current components in isolated hippocampal neurons. Journal of Neuroscience 8, 4069-4078.
8. JACOBSEN, J. S., SPRUYT, M. A., BROWN, A. M., SAHASRABUDHE, S. R., BLUME, A. J., VITEK, M. P., MUENKEL, H. A. & SONNENBERG-REINES, J. (1994). The release of Alzheimer's disease beta amyloid peptide is reduced by phorbol treatment. Journal of Biological Chemistry 269, 8376-8382.
9. KAZANIETZ, M. G., LEWIN, N. E., BRUNS, J. D. & BLUMBERG, P. M. (1995). Characterization of the cysteine-rich region of the Caenorhabditis elegans protein Unc-13 as a high affinity phorbol ester receptor. Journal of Biological Chemistry 270, 10777-10783.
10. 2+ differentiate presynaptic inhibition mediated by neuropeptide Y, baclofen, and 2-chloroadenosine in rat hippocampal CA1 in vitro. British Journal of Pharmacology 105, 470-474.
11. 2+ currents in mouse neuroblastoma cells. Journal of Physiology 419, 95-119.
12. MALLART, A. (1985). A calcium-activated potassium current in motor nerve terminals of the mouse. Journal of Physiology 368, 577-591.
13. NISHIZUKA, Y. (1986). Studies and perspectives of protein kinase C. Science 233, 305-312.
14. NISHIZUKA, Y. (1988). The molecular heterogeneity of protein kinase C and its implications for cellular regulation. Nature 334, 661-665.
15. 2+ current in sensory neurones. Proceedings of the National Academy of Sciences of the USA 83, 184-188.
16. REDMAN, R. S. & SILINSKY, E. M. (1994). ATP released together with acetylcholine is the mediator of neuromuscular depression at frog motor nerve endings. Journal of Physiology 477, 117-127.
17. REDMAN, R. S. & SILINSKY, E. M. (1995). On the simultaneous electrophysiological measurements of neurotransmitter release and perineural calcium currents from frog motor nerve endings. Journal of Neuroscience Methods 57, 151-159.
18. SCANZIANI, M., CAPOGNA, M., GAHWILER, B. H. & THOMPSON, S. M. (1992). Presynaptic inhibition of miniature excitatory synaptic currents by baclofen and adenosine in the hippocampus. Neuron 9, 919-927.
19. SCHOLZ, K. P. & MILLER, R. J. (1992). Inhibition of quantal transmitter release in the absence of calcium influx by a G protein-linked adenosine receptor at hippocampal synapses. Neuron 8, 1139-1150.
20. SEBASTIAO, A. M. & RIBEIRO, J. A. (1990). Interactions between adenosine and phorbol esters or lithium at the frog neuromuscular junction. British Journal of Pharmacology 100, 55-62.
21. SHAPIRA, R., SILBERBERG, S. D., GINSBURG, S. & RAHAMIMOFF, R. (1987). Activation of protein kinase C augments evoked transmitter release. Nature 325, 58-60.
22. SILINSKY, E. M. (1981). On the calcium receptor that mediates depolarization-secretion coupling at cholinergic motor nerve terminals. British Journal of Pharmacology 73, 413-429.
23. SILINSKY, E. M. (1984). On the mechanism by which adenosine receptor activation inhibits the release of acetylcholine from motor nerve endings. Journal of Physiology 346, 243-256.
24. SILINSKY, E. M. (1985). The biophysical pharmacology of calcium-dependent acetylcholine secretion. Pharmacological Reviews 37. 81-131.
25. SILINSKY, E. M. & SOLSONA, C. S. (1992). Calcium currents at motor nerve endings: absence of effects of adenosine receptor agonists in the frog. Journal of Physiology 457, 315-328.
26. WARDELL, C. F. & CUNNANE, T. C. (1994). Biochemical machinery involved in the release of ATP from sympathetic nerve terminals. British Journal of Pharmacology 111, 975-977.
27. 2+-dependent action potentials of mouse central and peripheral neurons in cell culture. Journal of Neuroscience 7, 1639-1647.
28. 2+ sensitivity of exocytosis in the chick ciliary presynaptic terminal. Journal of Physiology 493, 385-391.