Triple colour fluorescent in-situ hybridization for chromosomes X, Y and 1 on spare human embryos

Human Reproduction

Volumn 12, Issue 4, 1997, Pages 809-814

  Laverge, H ^a   De Sutter, P ^a   Verschraegen Spae, M R ^a   De Paepe, A ^a   Dhont, M ^a  

^a GHENT UNIVERSITY HOSPITAL   (Belgium)

Author keywords

Aneuploidy; Chromosomes; Fluorescent in situ hybridization; Human preimplantation embryos; Mosaicism

Indexed keywords

ANEUPLOIDY; ARTICLE; BLASTOMERE; CHROMOSOME 1; CHROMOSOME ABERRATION; CHROMOSOME ANALYSIS; DIPLOIDY; DNA PROBE; EMBRYO; FLUORESCENCE IN SITU HYBRIDIZATION; HAPLOIDY; HUMAN; MAJOR CLINICAL STUDY; MULTINUCLEAR CELL; TETRAPLOIDY; TRIPLOIDY; X CHROMOSOME; Y CHROMOSOME;

EID: 0030997783     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/12.4.809     Document Type: Article

References (35)

1. Angell, R.R., Sumner, A.T., West, J.D. et al. (1987) Post-fertilization polyploidy in human preimplantation embryos fertilized in vitro. Hum. Reprod., 2, 721-727.
2. Bacchus, C. and Buselmaier, W. (1988) Elastomere karyotyping and transfer of chromosomally selected embryos. Implications for the production of specific animal models and human prenatal diagnosis. Hum. Genet., 80, 333-336.
3. Bonduelle, M., Legein, J., Derde, M.-P. et al. (1995) Comparative follow-up of 130 children born after intracytoplasmic sperm injection and 130 children born after in-vitro fertilization. Hum. Reprod., 10, 3327-3331.
4. Bonduelle, M., Legein, J., Buysse, A. et al. (1996) Prospective follow-up of 423 children born after intracytoplasmic sperm injection. Hum. Reprod., 11, 1558-1564.
5. Boué, J. and Boué, A. (1976) Chromosomal anomalies in early spontaneous abortion. Curr. Top. Pathol., 62, 193-208.
6. Cooke, H.J. and Hindley, J. (1979) Cloning of the human satellite III DNA: Different components are on different chromosomes. Nucleic Acids Res., 6, 3177-3179.
7. Cooke, H.J., Schmidtke, J. and Gosden, J.R. (1982) Characterisation of a human Y chromosome repeated sequence and related sequences in higher primates. Chromosoma, 87, 491-502.
8. Coonen, E., Dumoulin, J.C.M., Ramaekers F.C.S. et al. (1994) Optimal preparation of preimplantation embryo interphase nuclei for analysis by fluorescent in-situ hybridization. Hum. Reprod., 3, 533-537.
9. Coulam, C.B., Opsahl, M.S., Sherins, R.J. et al. (1996) Comparisons of pregnancy loss patterns after intracytoplasmic sperm injection and other reproductive technologies. Fertil. Steril., 65, 1157-1162.
10. Delhanty, J.D.A. and Handyside, A.H. (1995) The origin of genetic defects in the human and their detection in the preimplantation embryo. Hum. Reprod. Update, 1, 201-215.
11. Gosden, C.M., Davidson, C. and Robertson, M. (1992) Lymphocyte culture. In Rooney, D.E. and Czepulkowski, B.H. (eds), Human Cytogenetics: A Practical Approach, 2nd edn. IRL Press, Oxford, pp. 31-54.
12. Handyside, A.H. (1996) Preimplantation genetic diagnosis today. Hum. Reprod., 11 (Suppl), 139.
13. Hardy, K., Winston, M.L. and Handyside, A.H. (1993) Binucleate blastomeres in preimplantation human embryos in vitro: failure of cytokinesis during early cleavage. J. Reprod. Fertil., 98, 549-558.
14. Harper, J.C., Coonen, E., Ramaekers, F.C.S. et al. (1994) Identification of the sex of human preimplantation embryos in two hours using an improved spreading method and fluorescent in-situ hybridization (FISH) using directly labelled probes. Hum. Reprod., 4, 721-724.
15. Harper, J.C., Coonen, E., Handyside, A.H. et al. (1995) Mosaicism of autosomes and sex chromosomes in morphologically normal, monospermic preimplantation human embryos. Prenatal Diagnosis, 15, 41-49.
16. In't Veld, P.A., Van Opstal, D., Van Den Berg, C. et al.(1995) Increased incidence of cytogenetic abnormalities in chorionic villus samples from pregnancies estabished by in-vitro fertilization and embryo-transfer (IVF-ET). Prenatal Diagnosis, 15, 975-980.
17. Kligman, I., Benadiva, C., Alikani, M. et al. (1996) The presence of multinucleated blastomeres in human embryos is correlated with chromosomal abnormalities. Hum. Reprod., 11, 1492-1498.
18. Machin, G.A. and Crolla, J.A. (1974) Chromosome constitution of 500 infants dying during the prenatal period. Humangenetik, 23, 183-198.
19. Munné, S. and Cohen, J. (1993) Unsuitability of multinucleated human blastomeres for preimplantion genetic diagnosis. Hum. Reprod., 8, 1120-1125.
20. Munné, S., Lee, A., Rozenwaks, Z. et al (1993) Diagnosis of major chromosome aneuploidies in human preimplantation embryos. Hum. Reprod., 8, 2185-2191.
21. Munné, S., Weier, H.U.G., Grifo, J. et al (1994) Chromosome mosaicism in human embryos. Biol. Reprod., 51, 373-379.
22. Munné, S., Khalid, M., Weier, H.-U. et al. (1995a) Assessment of numeric abnormalities of X, Y, 18 and 16 chromosomes in preimplantation human embryos before transfer. Am. J. Obstet. Gynaecol., 172, 1191-1199.
23. Munné, S., Alikani, M., Tomkin, G. et al (1995b) Embryo morphology, developmental rates and maternal age are correlated with chromosomal abnormalities. Fertil Steril., 64, 382-391.
24. Munné, S., Allikani, M., Tomkin, G. et al. (1995e) Embryo quality and chromosome abnormalities after ICSI (abstr). J. Assis. Genet., 12 (Suppl.), 76S.
25. Nielsen, J. (1975) Chromosome examination of newborn children. Purpose and ethical aspects. Humangenetik, 26, 215-222.
26. Papadopoulos, G., Templeton, A.A., Fisk, N. et al. (1989) The frequency of chromosome anomalies in human preimplantation embryos after in-vitro fertilization. Hum. Reprod., 4, 91-98.
27. Pellestor, F., Dufour, M.C., Arnal, F. et al. (1994) Direct assessment of the rate of chromosomal abnormalities in grade IV human embryos produced by in-vitro fertilization procedure. Hum. Reprod., 9, 293-302.
28. Plachot, M., Junca, A.M., Mandelbaum, J. et al. (1987) Chromosome investigations in early life. II. Human preimplantation embryos. Hum. Reprod., 2, 29-35.
29. Rufat, P., Olivennes, F., de Mouzon, J. et al. (1994) Task force report on the outcome of pregnancies and children conceived by in-vitro fertilization (France: 1987 to 1989). Fertil. Steril., 61, 324-330.
30. Testart, J., Plachot, M., Mandelbaum, J. et al. (1992) World collaborative report on IVF-ET and GIFT: 1989 results. Hum. Reprod., 7, 362-369.
31. Watt, J.L., Templeton, A.A., Messinis, I. et al. (1987) Trisomy 1 in an eight cell human pre-embryo. J. Med. Genet., 24, 60-64.
32. West, J.D., Gosden, C.M., Gosden, J.R. et al. (1989) Sexing the human fetus and identification of polyploid nuclei by DNA-DNA in situ hybridisation in interphase nuclei. Mol. Reprod. Devel., 1, 129-137.
33. Williard, H.F., Smith, K.D. and Sutherland, J. (1983) Isolation and characterisation of a major tandem repeat family from the human X chromosome. Nucleic Acids Res., 19, 3237-3241.
34. Wimmers, M.S. and Van der Merwe, J.V. (1988) Chromosome studies on early human embryos fertilized in vitro. Hum. Reprod., 3, 894-900.
35. Wisanto, A., Magnus, M., Bonduelle, M. et al. (1995) Obstetric outcome of 424 pregnancies after intracytoplasmic sperm injection. Hum. Reprod., 10, 2713-2718.