Oxygen-carrying blood substitutes

Infusionstherapie und Transfusionsmedizin

Volumn 24, Issue 2, 1997, Pages 114-120

  Waschke, K F ^a,b   Quintel, M ^a   Kerger, H ^a   Lenz, C ^a  

^a MEDICAL FACULTY MANNHEIM HEIDELBERG UNIVERSITY   (Germany)

^b Klinikum Mannheim   (Germany)

Author keywords

blood substitutes; hemoglobin modifications; perfluorocarbons; transfusion

Indexed keywords

FLUOROCARBON; HEMOGLOBIN DERIVATIVE; OXYGEN;

BLOOD SUBSTITUTION; BLOOD TRANSFUSION; CONFERENCE PAPER; CONTROLLED STUDY; HUMAN;

EID: 0030997760     PISSN: 10198466     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (62)

1. Hoppe-Seyler F: Über das Verhalten des Blutfarbstoffes im Spektrum des Sonnenlichtes. Arch Pathol Anat Physiol 1862;23:446-452.
2. Sellards AW, Minot GR: Injection of hemoglobin in man and its relation to blood destruction, with especial reference to the anemias. J Med Res 1916;34: 469-494.
3. Amberson WR: Blood substitutes. Biol Rev 1937;12: 48-86.
4. Amberson WR, Jennings JJ, Rhode M: Clinical experience with hemoglobin-saline solutions. J Appl Physiol 1949;1:469-489.
5. Chang TMS: Hemoglobin Corpuscles. Report of a Research Project of BSc Honours Physiology. Montreal, McGill University, 1957, pp 1-25.
6. Clark LC, Gollan F: Survival of mammals breathing organic liquids equilibrated with oxygen at atmospheric pressure. Science 1966;152:1755-1756.
7. Rabiner SF, Helbert JR, Lopas H, Friedman LH: Evaluation of a stroma-free hemoglobin for use as a plasma expander. J Exp Med 1967;126:1127-1142.
8. Geyer RP, Monroe RG, Taylor K: Survival of rats having red cells totally replaced by emulsified fluorocarbons. Fed Proc 1968;27:384-387.
9. Greenspan JS, Wolfson MR, Rubenstein SD, Shaffer TH: Liquid ventilation on preterm baby. Lancet 1989;2:1095.
10. Miller JH, McDonald RK: The effect of hemoglobin on renal function in the human. J Clin Invest 1951; 30:1033-1038.
11. Birndorf NI, Lopas HL, Robboy S: Disseminated intravascular coagulation and renal failures. Lab Invest 1971;25:314-321.
12. Benesch R, Benesch RE, Kwong S: Labeling of hemoglobin with pyridoxal phosphate. J Biol Chem 1982;257:147-158.
13. Benesch R, Benesch RE: Preparation and properties of hemoglobin modified with derivates of pyridoxal. Methods Enzymol 1981;76:147-159.
14. Keipert PE, Adeniran AJ, Kwong S, Benesch KE: Functional properties of a new cross-linked hemoglobin designed for use as a red cell substitute. Transfusion 1989;29:768-773.
15. Manning LR, Morgn S, Beavis RC, Chait BT, Manning JM, Hess JR, Cross M, Currel DL, Marini M, Winslow RM: Preparation, properties and plasma retention of human hemoglobin derivates: Comparison of uncrosslinked carboxymethylated hemoglobin with crosslinked tetrameric hemoglobin. Proc Natl Acad Sci USA 1991;88:3329-3333.
16. Fronticelli C, Sato T, Orth C, Bucci E: Bovine hemoglobin as a potential source of hemoglobin-based oxygen carriers: Crosslinking with bis(3,5-dibromosalicyl)fumarate. Biochem Biophys Acta 1986;874: 76-81.
17. De Venuto F, Zegna A: Preparation and evaluation of pyridoxylated-polymerized human hemoglobin. J Surg Res 1983;34:205-212.
18. Snyder SR, Welty EV, Walder RY: HbXL99a: A hemoglobin derivate that is crosslinked between the α-subunits is useful as a blood substitute. Proc Natl Acad Sci USA 1987;84:7280-7284.
19. Tam SC, Blumenstein J, Wong JT: Soluble dextran-hemoglobin complex as a potential blood substitute. Proc Natl Acad Sci USA 1976;73:2128-2132.
20. Schmidt K: Polyvinylpyrrolidon-gebundenes Hämoglobin als ein Sauerstoff übertragender Blutersatzstoff. Klin Wochenschr 1979;57:1169-1175.
21. Yabuki A, Yamaji K, Ohki H, Iwashita Y: Characterization of a pyridoxilated hemoglobin-polyoxyethylene conjugate as a physiologic oxygen carrier. Transfusion 1990;30:516-520.
22. Rabinovici R, Rudolph AS, Vernick J, Feuerstein G: Lyophilized liposome encapsulated hemoglobin: Evaluation of hemodynamic, biochemical, and hematological responses. Crit Care Med 1994;22: 480-485.
23. Rudolph AS: Encapsulated hemoglobin: Current issues and future goals. Artif Cells Blood Substit Immobil Biotechnol 1994;22:347-360.
24. Hoffman SJ, Looker DL, Roehrich JM, Cozart PE, Durfee SL, Tedesco JL, Stetler GL: Expression of fully functional tetrameric human hemoglobin in Escherichia coli. Proc Natl Acad Sci USA 1990; 87:8521-8523.
25. Wagenbuch M, O'Rourke K, Vitez L, Wieczorek A, Hoffman S, Durfee S, Tedesco J, Stetler G: Synthesis of wild type and mutant human hemoglobins in Saccharomyces cerevisiae. Biotechnology 1991;9: 57-61.
26. Behringer RR, Ryan TM, Reilly MP: Synthesis of functional human hemoglobin in transgenic mice. Science 1989;245:971-973.
27. Swanson ME, Martin MJ, O'Donnell JK, Hoover K, Lago W, Huntress V, Parsons CT, Pinkert CA, Pilder S, Logan JS: Production of functional human hemoglobin in transgenic swine. Biotechnology 1992;10: 556-559.
28. Komiyama NH, Miyazaki G, Tame J, Nagai K: Transplanting a unique allosteric effect from crocodile into human haemoglobin. Nature 1995;373: 244-246.
29. Moncada S, Palmer RMJ, Higgs EA: Nitric oxide: Physiology, pathophysiology and pharmacology. Pharmacol Rev 1991;43:109-142.
30. Schultz SC, Grady B, Cole F, Hamilton I, Burhop K: A role for endothelin and nitric oxide in the pressor response to diaspirin cross-linked hemoglobin. J Lab Clin Med 1993;122:301-308.
31. Evans T, Carpenter A, Kinderman H, Cohen J: Evidence of increased nitric oxide production in patients with the sepsis syndrome. Circ Shock 1993; 41:77-81.
32. Kilbourn RG, Joly G, Cashon B: Cell-free hemoglobin reverses the endotoxin-mediated hyporesponsivity of rat aortic rings to α-adrenergic agents. Biochim Biophys Res Commun 1994;199:155-162.
33. Gould SA, Rosen AL, Sehgal LR, Sehgal HL, Langdale LA, Krause LM, Rice CL, Chamberlin WH, Moss GS: Fluosol-DA as a red cell substitute in acute anemia. N Engl J Med 1986;14:1653-1656.
34. Kerins DM: Role of the perfluorocarbon Fluosol-DA in coronary angioplasty. Am J Med Sci 1994; 307:218-221.
35. Vercellotti GM, Hammerschmidt DE, Craddock PR, Jacob HS: Activation of plasma complement by perfluorocarbon artificial blood: Probable mechanism of adverse pulmonary reactions in treated patients and rationale for corticosteroid prophylaxis Blood 1982;59:1299-1304.
36. Virmani R, Warren D, Rees R, Fink LM, English D: Effects of perfluorochemical on phagocytic function of leukocytes. Transfusion 1983;23:512-515.
37. Wahr JA, Trouwborst A, Spence RK, Henny CP, Cernaianu AC, Graziano GP, Tremper KK, Flaim KE, Faithfull NS, Clymer JJ: A pilot study of the effects of a perflubron emulsion, AF 0104, on mixed venous oxygen tension in anesthetized surgical patients. Anesth Analg 1996;82:103-107.
38. Tremper KK, Cullen BF: US clinical studies of the treatment of anemia with Fluosol-DA 20%. Artif Organs 1984;8:19-24.
39. Tremper KK, Lapin R, Levine E, Friedman A, Shoemaker WC: Hemodynamic and oxygen transport effects of a perfluorochemical blood substitute, Fluosol-DA (20%). Crit Care Med 1980;8:738-741.
40. 2 extraction following hemodilution with Dextran or Fluosol-DA. J Crit Care 1988;3:14-18.
41. 2 carrier in conscious rats. Am J Physiol 1993;256:H1243-H1248.
42. Sloviter HA, Petkovic M, Ogoshi S, Yamada H: Dispersed fluorochemicals as substitutes for erythrocytes in intact animals. J Appl Physiol 1969;2: 666-668.
43. Bosman RJ, Minten J, Lu HR, van Aken H, Flameng W: Free polymerized hemoglobin versus hydroxyethyl starch in resuscitation of hypovolemic dogs. Anesth Analg 1992;75:811-817.
44. Waschke KF, Albrecht DM, van Ackern K, Kuschinsky W: Autoradiographic determination of regional cerebral blood flow and metabolism in conscious rats after fluid resuscitation from haemorrhage with a haemoglobin-based oxygen carrier. Br J Anaesth 1994;73:522-528.
45. Przybelski RJ, Malcolm DS, Burris DG, Winslow RM: Cross-linked hemoglobin solution as a resuscitate fluid after hemorrhage in the rat. J Lab Clin Med 1991;117:143-151.
46. Waschke KF, Riedel M, Albrecht DM, van Ackern K, Kuschinsky W: Effects of a perfluorocarbon emulsion on regional cerebral blood flow and metabolism after fluid resuscitation from hemorrhage in conscious rats. Anesth Analg 1994;79:874-882.
47. Oldham KT, Guice KS, Gore D: Treatment of intestinal ischemia with oxygenated intraluminal perfluorocarbons. Am J Surg 1987;153:291-294.
48. Takahashi F, Tsai TM, Fleming PE, Ogden L: The ability of oxygenated fluorocarbon solution to minimize skeletal muscle injury. Plast Reconstr Surg 1987;80:582-590.
49. Cole DJ, Schell RM, Drummond JC, Reynolds L: Focal cerebral ischemia in rats. Effect of hypervolemic hemodilution with diaspirin cross-linked hemoglobin versus albumin on brain injury and edema. Anesthesiology 1993;78:335-342.
50. Peerless SJ, Ishikawa R, Hunter IG, Peerless MJ: Protective effect of Fluosol-DA in acute cerebral ischemia. Stroke 1981;193:206-209.
51. Skibba JL, Sonsalla J, Petroff RJ, Denor P: Canine liver isolation-perfusion at normo- and hyperthermic temperatures with perfluorochemical emulsion (Fluosol-43). Eur Surg Res 1985;17:301-309.
52. Fuchinoue S, Takahashi K, Toma H, Ashishi T, Ota K: Clinical experience in kidney preservation with a new fluorocarbon emulsion perfusate. Transplant Proc 1986;18:566-570.
53. Teicher BA, Rose CM: Perfluorochemical emulsions can increase tumor radiosensitivity. Science 1984;223:934-936.
54. Teicher BA, McIntosh-Lowe NL, Rose CM: Effect of various oxygenation conditions and Fluosol-DA on cancer chemotherapeutic agents. Biomat Artif Cells Artif Organs 1988;16:533-537.
55. Spiess BD, Braverman B, Woronowicz AW, Ivankovich AD: Protection from cerebral air emboli with perfluorocarbon emulsions in rabbits. Stroke 1986;17:1146-1149.
56. Spiess BD, McCarthy RJ, Tuman KJ: Treatment of decompression sickness with a perfluorocarbon emulsion (FC-43). Undersea Biomed Res 1988;15: 31-37.
57. Mattrey RF: Perfluorooctylbromide: A new contrast agent for CT, sonography, and MR imaging. Am J Radiol; 152:247-252.
58. Boernert P, Dreher W, Schneider W: 19F chemical shift imaging in perfluorocarbons. NMR Biomed 1989;2:278-283.
59. Rubin DL, Muller HH, Nino-Murda M, Sidhu M, Christy V, Young SW: Intraluminal contrast enhancement and MR visualization of the bowel wall: Efficacy of PFOB. J Magn Reson Imaging 1991;1: 371-380.
60. Fuhrman BP, Paczan PR, DeFrancis M: Perfluorocarbon-associated gas exchange. Crit Care Med 1991;19:712-722.
61. Shaffer TH, Wolfson MR, Clark LC: State of the art review: Liquid ventilation. Pediatr Pulmonol 1992; 14:102-109.
62. Hirschl RB, Pranikoff T, Gauger P, Schreiner RJ, Dechert R, Bartlett RH: Liquid ventilation in adults, children, and full-term neonates. Lancet 1995;46:1201-1202.