Inhibitory effects of NS-21, a novel drug for urinary incontinence, and its active metabolite, RCC-36, on L-type calcium currents in isolated guinea pig detrusor smooth muscle cells

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 355, Issue 5, 1997, Pages 659-666

  Hayashi, Seiji ^a   Natsukawa, Takashi ^a   Ukai, Yojiro ^a   Yoshikuni, Yoshiaki ^a   Kimura, Kiyoshi ^a  

^a NIPPON SHINYAKU CO LTD   (Japan)

Author keywords

Ca2+ Antagonist; Calcium window current; Inward current; Patch clamp; Terodiline; Voltage dependence

Indexed keywords

2 CYCLOHEXYL 2 HYDROXY 2 PHENYLACETIC ACID 4 ETHYLAMINO 1,1 DIMETHYL 2 BUTYNYL ESTER; CALCIUM ANTAGONIST; TEMIVERINE; TERODILINE; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CURRENT; CONTROLLED STUDY; DETRUSOR MUSCLE; GUINEA PIG; NONHUMAN; PATCH CLAMP; SMOOTH MUSCLE FIBER;

ANIMALS; BUTYLAMINES; CALCIUM; CALCIUM CHANNEL BLOCKERS; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; GUINEA PIGS; MALE; MUSCLE, SMOOTH; PARASYMPATHOLYTICS; PATCH-CLAMP TECHNIQUES; PHENYLACETATES; URINARY BLADDER; URINARY INCONTINENCE;

EID: 0030997270     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/PL00004998     Document Type: Article

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