Quantification and genotyping of serum HCV-RNA in patients with chronic hepatitis C undergoing interferon treatment

Archives of Virology

Volumn 142, Issue 3, 1997, Pages 459-464

  Gerken, G ^a   Knolle, P ^a   Jakobs, S ^a   Meyer Zum Buschenfelde K H ^a  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA2A INTERFERON; ALPHA2B INTERFERON; ANTIVIRUS AGENT; VIRUS RNA;

ADULT; AGED; ARTICLE; BLOOD; CLASSIFICATION; EVALUATION; FEMALE; FOLLOW UP; GENETICS; GENOTYPE; HEPATITIS C; HEPATITIS C VIRUS; HUMAN; ISOLATION AND PURIFICATION; MALE; METHODOLOGY; MIDDLE AGED; POLYMERASE CHAIN REACTION; VIROLOGY;

ADULT; AGED; ANTIVIRAL AGENTS; EVALUATION STUDIES; FEMALE; FOLLOW-UP STUDIES; GENOTYPE; HEPACIVIRUS; HEPATITIS C, CHRONIC; HUMANS; INTERFERON ALFA-2A; INTERFERON ALFA-2B; MALE; MIDDLE AGED; POLYMERASE CHAIN REACTION; RNA, VIRAL;

HEPATITIS C VIRUS;

EID: 0030997098     PISSN: 03048608     EISSN: None     Source Type: Journal    
DOI: 10.1007/s007050050092     Document Type: Article

References (19)

1. Bonino F, Brunetto MR, Negro Baldi M, Saracco G, Abate ML, Fabiano A, Verme G (1993) Hepatitis C virus infection and disease. Diagnostic problems. J Heptol 17 [Suppl 3]: 78-82
2. Bréchot C (1993) Polymerase chain reaction for the diagnosis of hepatitis B and C viral hepatitis. J Hepatol 17 [Suppl 3]: 35-41
3. Zaaijer HL, Cuypers HT, Reesink HW, Winkel IN, Gerken G, Lelie PN (1993) Reliability of polymerase chain rection for detection of hepatitis C virus. Lancet 341: 722
4. Lau JY, Davis GL, Kniffen J (1993) Significance of serum hepatitis C virus RNA levels in chronic hepatitis C. Lancet 341: 1 501-1 504
5. Brillianti S, Garson JA, Tuke PW (1991) Effect of α-interferoń therapy on hepatitis C viremia in community acquired chronic non-A non-B hepatitis: a quantitative polymcrase chain reaction study. J Med Virol 34: 136-141
6. Davis GL, Lau JYN, Ureda MS, Neuwald PD, Wilber JC, Lindsay K, Perillo PP, Albrecht J (1994) Quantitative detection of hepatitis C virus RNA with a solid-phase signal amplification method: definition of optimal conditions for specimen collection and clinical application in interferon-treated patients. Hepatology 19: 1 337-1 341
7. Kaneko S, Murakami S, Unoura M, Kobayashi K (1992) Quantitation of hepatitis C virus RNA by competitive polymerase chain reaction. J Med Virol 37: 278-282
8. Kato N, Yokosuka O, Hosoda K, Ito Y, Ohto M, Omata M (1993) Quantification of hepatitis C virus by competitive polymerase chain reaction: increase of the virus in advanced liver disease. Hepatology 18: 16-20
9. Goergen B, Jakobs S, Symmons P, Homes E, Meyer zum Büschenfelde K-H. Gerken G (1994) Quantitation of HCV-replication using one-step competitive RT-PCR and a solid phase, colorimetric detection method. J Hepatol 21: 678-682
10. Desmet VJ, Gerber M, Hoofnagle J, Manns H, Schever PJ (1994) Classification of chronic hepatitis: Diagnosis, grading and staging. Hepatology 19: 1 513-1 520
11. Pugh RNH, Murray-Lyon IM, Dawson JL (1973) Transsection of the oesophagus for bleeding for oesophageal varices. J Surg 60: 646-649
12. Goergen B, Jakobs S, Meyer zum Büschenfelde K-H, Gerken G (1994) Assessment of viral replication for routine diagnosis of HCV infection and for monitoring antiviral treatment using Amplicor HCV detection system. Clin Lab 40: 991-997
13. Gerken G, Pontisso P, Roggendorf M, Rumi MG, Simmonds P, Trepo C, Zeuzem S, Colucci G (1995) Clinical evaluation of single reaction, diagnostic PCR assay for the detection of hepatitis C virus (HCV) RNA. J Hepatol 1: 1 1
14. Simmonds P, McOmish F, Yap PL (1993) Sequence variability in the 5′ non-coding region of hepatitis C virus: identification of a new virus type and restrictions on sequence diversity. J Gen Virol 74: 661-668
15. Stuyver L, Rossau R, Wyseur A, Duhamel M, Vanderborght B, van Heuverswyn H, Maertens G (1993) Typing of hepatitis C virus isolates and characterization of new subtypes using a line probe assay. J Gen Virol 74: 1 105-1 113
16. Battezzati PM, Podda M, Bruno S (1992) Factors predicting early response to treatment with recombinant interferon α-2a in chronic non-A, non-B hepatitis. Preliminary report on a long term trial. Ital J Gastroenterol 24: 481-484
17. Trépo C, Habersetzer F, Bailly F, Berby F, Pichoud C, Bertlillou P, Vivitski L (1993) Factors of response to antiviral treatments in chronic hepatitis C. In: Miguet J-P, Dhumeaux D (eds) Progress in hepatology 93. John Libbey Eurotext, Paris, pp 69-77
18. Gerken G, Teuber G, Goergen B, Meyer zum Büschenfelde K-H (1995) Interferon-α treatment in chronic hepatitis C. J Hepatol 22 [Suppl 1]: 118-121
19. Kobayashi Y, Watanabe S, Konishi M, Yokai M, Katehashi R, Kailo M, Kondo M, Hayashi Y, Jonori T, Suzuki S (1993) Quantitation and typing of serum hepatitis C virus RNA in patients with chronic hepatitis C treated with interferon-β. Hepatology 18: 1319-1325