Autocrine interleukin-1 receptor antagonist can support malignant growth of glioblastoma by blocking growth-inhibiting autocrine loop of interleukin-1

International Journal of Cancer

Volumn 71, Issue 6, 1997, Pages 1066-1076

  Oelmann, Elisabeth ^a   Kraemer, Annette ^a   Serve, Hubert ^a   Reufi, Birgit ^a   Oberberg, Dorothea ^a   Patt, Stephan ^b   Herbst, Hermann ^a   Stein, Harald ^a   Thiel, Eckhard ^a   Berdel, Wolfgang E ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; RECOMBINANT INTERLEUKIN 1;

ADULT; ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; GLIOBLASTOMA; GROWTH STIMULATION; HUMAN; HUMAN TISSUE; IN SITU HYBRIDIZATION; PRIORITY JOURNAL;

BINDING SITES; BRAIN NEOPLASMS; CELL DIVISION; GLIOBLASTOMA; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; RECEPTORS, INTERLEUKIN-1; SIALOGLYCOPROTEINS; THYMIDINE; TUMOR CELLS, CULTURED;

EID: 0030996888     PISSN: 00207136     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0215(19970611)71:6<1066::AID-IJC25>3.0.CO;2-A     Document Type: Article

References (72)

1. AREND, W.P., Interleukin-1 receptor antagonist. Adv. Immunol., 54, 167-227 (1993).
2. AREND, W.P., WELGUS, H.G., THOMPSON, R.C. and EISENBERG, S.P., Biological properties of recombinant human monocyte-derived interleukin 1 receptor antagonist. J. clin. Invest., 85, 1694-1697 (1990).
3. BANI, M.R., GAROFALO, A., SCANZIANI, E. and GIAVAZZI, R., Effect of interleukin-1 beta on metastasis formation in different tumor systems. J. nat. Cancer Inst., 83, 119-123 (1991).
4. BERTOGLIO, J.H., RIMSKY, L., KLEINERMAN, E.S. and LACHMAN, L.B., B-cell line-derived imerleukin 1 is cytotoxic for melanoma cells and promotes the proliferation of an astrocytoma cell line. Lymphokine Res., 6, 83-91 (1987).
5. COLOTTA, F., RE, F., MUZIO, M., BERTINI, R., POLENTARUTTI, N., SIRONI, M., GIRI, J.G., DOWER, S.K., SIMS, J.E. and MANTOVANI, A., Interleukin-1 type II receptor: a decoy target for IL-1 that is regulated by IL-4. Science, 261, 472-475 (1993).
6. CROWN, J. and 15 OTHERS, A phase I trial of recombinant human interleukin-1β alone and in combination with myelosuppressive doses of 5-fluorouracil in patients with gastrointestinal cancer. Blood, 78, 1420-1427 (1991).
7. DANFORTH, JR., D.N. and SGAGIAS, M.K., Interleukin-1α and interleukin-6 act additively to inhibit crowth of MCF-7 breast cancer cells in vitro. Cancer Res., 53, 1538-1545 (1993).
8. DINARELLO, C.A., Interleukin-1 and interleukin-1 antagonism. Blood, 77, 1627-1652 (1991).
9. DINARELLO, C.A., The biological properties of interleukin-1. Europ. Cytokine Netw., 5, 517-531 (1994).
10. DINARELLO, C.A., Biologic basis for Interleukin-1 in disease. Blood, 87, 2095-2147 (1996).
11. DINARELLO, C.A. and THOMPSON, R.C., Blocking IL-1: interleukin 1 receptor antagonist m vivo and in vitro. Immunol. Today, 12, 404-410 (1991).
12. DRIPPS, D.J., BRANDHUBER, B.J., THOMPSON, R.C. and EISENBERG, S.P., Interleukin-1 (IL-1) receptor antagonist binds to the 80-kDa IL-1 receptor but does not initiate IL-1 signal transduction. J. biol. Chem., 266, 10331-10336 (1991).
13. EISENBERG, S.P., EVANS, R.J., AREND, W.P., VERDERBER, E., BREWER, M.T., HANNUM, C.H. and THOMPSON, R.C., Primary structure and functional expression from complementary DNA of a human interleukin-1 receptor antagonist. Nature (Lond.), 343, 341-346 (1990).
14. ESTROV, Z., KURZROCK, R., WETZLER, M., KANTARJIAN, H., BLAKE, M., HARRIS, D., GUTTERMAN, J.U. and TALPAZ, M., Suppression of chronic myelogenous leukemia colony growth by interleukin-1 (IL-1) receptor antagonist and soluble IL-1 receptors: a novel application for inhibitors of IL-1 activity. Blood, 78, 1476-1484 (1991).
15. FISCHER, E., VAN ZEE, K.J., MARANO, M.A., ROCK, C.S., KENNEY, J.S., POUTSIAKA, D.D., DINARELLO, C.A., LOWRY, S.F. and MOLDAWER, L.L., Interleukin-1 receptor antagonist circulates in experimental inflammation and in human disease. Blood, 79, 2196-2200 (1992).
16. 6 glioma cells. J. Immunol., 129, 2413-2419 (1982).
17. FREEDMAN, V.H. and SHIN, S., Cellular tumorigenicity in nude mice: correlation with cell growth in semi-solid medium. Cell, 3, 355-359 (1974).
18. GAFFNEY, E.V. and TSAI, S.C., Lymphocyte-activating and growth-inhibitory activities for several sources of native and recombinant interleukin 1. Cancer Res., 46, 3834-3837 (1986).
19. GAROFALO, A., CHIRIVI, R.G.S., FOGLIENI, C., PIGOTT, R., MORTARINI, R., MARTIN-PADURA, I., ANICHINI, A., GEARING, A.J., SANCHEZ- MADRID, F., DEJANA, E. and GIAVAZZI, R., Involvement of the very late antigen 4 integrin on melanoma in interleukin I-augmented experimental metastases. Cancer Res., 55, 414-419 (1995).
20. GIULIAN, D., BAKER, T.J., SHIH, L.-C.N. and LACHMAN, L.B., Interleukin 1 of the central nervous system is produced by ameboid microglia. J. exp. Med., 164, 594-604 (1986).
21. GIULIAN, D. and LACHMAN, L.B., Interleukin-1 stimulation of astroglial proliferation after brain injury. Science, 228, 497-499 (1985).
22. GIULIAN, D., YOUNG, D.G., WOODWARD, J., BROWN, D.C. and LACHMAN, L.B., Interleukin-1 is an astroglial growth factor in the developing brain. J. Neurosci., 8, 709-714 (1988).
23. GRANOWITZ, E.V., CLARK, B.D., MANCILLA, J. and DINARELLO, C.A., Interleukin-1 receptor antagonist competitively inhibits the binding of interleukin-1 to the type II interleukin-1 receptor. J. biol. Chem., 266, 14147-14150 (1991a).
24. GRANOWITZ, E.V., CLARK, B.D., VANNIER, E., CALLAHAN, M.V. and DINARELLO, C.A., Effect of interleukin-1 (IL-1) blockade on cytokine synthesis: I. IL-1 receptor antagonist inhibits IL-1-induced cytokine synthesis and blocks the binding of IL-1 to its type II receptor on human monocytes. Blood, 79, 2356-2363 (1992).
25. GRANOWITZ, E.V., SANTOS, A.A., POUTSIAKA, D.D., CANNON, J.G., WILMORE, D.W., WOLFF, S.M. and DINARELLO, C.A., Production of interleukin-1-receptor antagonist during experimental endotoxaemia. Lancet, 338, 1423-1424 (1991b).
26. GROSS, J.L., BEHRENS, D.L., MULLINS, D.E., KORNBLITH, P.L. and DEXTER, D.L., Plasminogen activator and inhibitor activity in human glioma cells and modulation by sodium butyrate. Cancer Res., 48, 291-296 (1988).
27. GRUSS, P., SPOHR, A., LEIBER, A., TASLER, J., MENZL, H. and HOFSTÄDTER, F., On the questions of traumatic origin in a glioblastoma. Zentralbl. Neurochir., 54, 186-189 (1993).
28. HAMBURGER, A.W., LURIE, K.A. and CONDON, M.E., Stimulation of anchorage-independent growth of human tumor cells by interleukin 1. Cancer Res., 47, 5612-5615 (1987).
29. HANAUSKE, A.R., DEGEN, D., MARSHALL, M.H., HILSKNBECK, S.G., BANKS, P., STUCKEY, J., LEAHY, M. and VON HOFF, D.D., Effects of recomhinant human interleukin-1α on clonogenic growth of primary human tumors in vitro. J. Immunother., 11, 155-158 (1992).
30. HASKILL, S., MARTIN, G., VAN LEE, L., MOKRIS, J., PEACE, A., BIGLER, C.F., JAFFE, G.J., HAMMERBERG, C., SPORN, S.A., FONG, S., AREND, W.P. and RALPH, P., cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium. Proc. nat. Acad. Sci. (Wash.), 88, 3681-3685 (1991).
31. HERBST, H., STEINBRECHER, T., NIEDOBITEK, G., YOUNG, L.S., BROOKS, L., MÜLLER-LANTZSCH, N. and STEIN, H., Distribution and phenotype of Epstein-Barr virus-harboring cells in Hodgkin's disease. Blood, 80, 484-491 (1992).
32. HETIER, E., AYALA, J., DENÈFLE, P., BOUSSEAU, A., ROUGET, P., MALLAT, M. and PROCHIANTZ, A., Brain macrophages synthesize interleukin-1 and interleukin-1 mRNAs in vitro. J. Neurosci. Res., 21, 391-397 (1988).
33. ITO, R., KITADAI, Y., KYO, E., YOKOZAKI, H., YASUI, W., YAMASHITA, U., NIKAI, H. and TAMARA, E., Interleukin 1α acts as an autocrine growth stimulator for human gastric carcinoma cells. Cancer Res., 53, 4102-4106 (1993).
34. KILIAN, P.L., KAFFKA, K.L., BIONDI, D.A., LIPMAN, J.M., BENJAMIN, W.R., FELDMAN, D. and CAMPEN, C.A., Antiproliferative effect of interleukin-1 on human ovarian carcinoma cell line (NIH:OVCAR-3). Cancer Res., 51, 1823-1828 (1991).
35. KOCH, I., DEPENBROCK, H., DANHAUSER-RIEDL, S., RASTETTER, J.W. and HANAUSKE, A.R., Interleukin 1 modulates growth of human renal carcinoma cells in vitro. Brit. J. Cancer, 71, 794-800 (1995).
36. LACHMAN, L.B., BROWN, D.C. and DINARELLO, C.A., Growth-promoting effect of recombinant interleukin 1 and tumor necrosis factor for a human astrocytoma cell line. J. Immunol., 138, 2913-2916 (1987).
37. LACHMAN, L.B., DINARELLO, C.A., LLANSA, N.D. and FIDLER, I.J., Natural and recombinant human interleukin 1-β is cytotoxic for human melanoma cells. J. Immunol., 136, 3098-3102 (1986).
38. 1. Europ. J. Cancer, 28A, 1894-1899 (1992).
39. LARRICK, J.W., Native interleukin 1 inhibitors. Immunol. Today, 10, 61-65 (1989).
40. LEE, J.C., SIMON, P.L. and YOUNG, P.R., Constitutive and PMA-induced interleukin-1 production by the human astrocytoma cell line T24. Cell. Immunol., 118, 298-311 (1989).
41. MALIPIERO, U.V., FREI, K. and FONTANA, A., Production of hemopoietic colony-stimulating factors by astrocytes. J. Immunol., 144, 3816-3821 (1990).
42. MARSHALL, G.M., VANHAMME, L., WONG, W.Y., SU, H. and VOGT, P.K., Wounding acts as a tumor promotor in chickens inoculated with avian sarcoma virus 17. Virology, 188, 373-377 (1992).
43. MCKINNON, R.D., PIRAS, G., IDA, J.A., JR. and DUBOIS-DALCQ, M., A role for TGF-β in oligodendrocyte differentiation. J. Cell Biol., 121, 1397-1407 (1993).
44. MERLO, A., JURETIC, A., ZUBER, M., FILGUEIRA, L., LÜSCHER, U., CAETANO, V. ULRICH, J., GRATZL, O., HEBERER, M. and SPAGNOLI, G.C., Cytokine gene expression in primary brain tumours, metastases and meningiomas suggests specific transcription patterns. Europ. J. Cancer, 29A, 2118-2125 (1993).
45. MERRILL, J.E., Macroglia: neural cells responsive to lymphokines and growth factors. Immunol. Today, 8, 146-150 (1987).
46. MERZAK, A., KOOCHEKPOUR, S., DKHISSI, F., RAYNAL, S., LAWRENCE, D. and PILKINGTON, G.J., Synergism between growth factors in the control of glioma cell proliferation, migration and invasion in vitro. Int. J. Oncol., 6, 1079-1085 (1995).
47. MILANI, S., HERBST, H., SCHUPPAN, D., HAHN, E.G. and STEIN, H., In situ hybridization for procollagen types I, III and IV mRNA in normal and fibrotic rat liver. Evidence for predominant expression in nonparenchymal liver cells. Hepatology, 10, 84-92 (1989).
48. OELMANN, E., SRETER, L., SCHULLER, I., SERVE, H., KOENIGSMANN, M., WIEDENMANN, B., OBERBERG, D., REUFI, B., THIEL, E. and BERDEL, W.E., Nerve growth factor stimulates clonal growth of human lung cancer cell lines and a glioblastoma cell line expressing high-affinity nerve growth factor binding sites involving tyrosine kinase signalling. Cancer Res., 55, 2212-2219 (1995).
49. OELMANN, E., TOPP, M.S., REUFI, B., PAPADIMITRIOU, C., KOENIGSMANN, M., OBERBERG, D., THIEL, E. and BERDEL, W.E., Interleukin-1 receptor antagonist inhibits growth modulation of human tumor cell lines by interleukin-1 in vitro. Int. J. Oncol., 4, 555-558 (1994).
50. ONOZAKI, K., MATSUSHIMA, K., AGGARWAL, B.B. and OPPENHEIM, J.J., Human interleukin 1 is a cytocidal factor for several tumor cell lines. J. Immunol., 135, 3962-3968 (1985).
51. PLATANIAS, L.C. and VOGELZANG, N.J., Interleukin-1: biology, pathophysiology, and clinical prospects. Amer. J. Med., 89, 621-629 (1990).
52. REDMAN, B.G., ABUBAKR, Y., CHOU, T., ESPER, P. and FLAHERTY, L.E., Phase II trial of recombinant interleukin-1β in patients with metastatic renal cell carcinoma [Abstract]. Proc. ASCO, 13, 805 (1994).
53. ROTHWELL, N.J., Functions and mechanisms of interleukin 1 in the brain. Trends Pharmacol. Sci., 12, 430-436 (1991).
54. SCHMIDT, J.A. and TOCCI, M.J., Interleukin-1. In: M.B. Sporn and A.B. Roberts (eds.), Peptide growth factors and their receptors I, pp. 473-521, Springer-Verlag, New York (1991).
55. SCHUCHTER, L., NEUBERG, D., ATKINS, M., TESTER, B., RECLO, A., SICKLES, C., MOORE, J., LIGHT, B., ANDERSON, T., CHACHOUA, A. and DUTCHER, J., A phase I study of interleukin-1 alpha (IL-1) and high dose cyclophosphamide (Cy) in patients with advanced cancer [Abstract]. Proc. ASCO, 13, 327 (1994).
56. SIMS, J.E., GAYLE, M.A., SLACK, J.L., ALDERSON, M.R., BIRD, T.A., GIRI, J.G., COLOTTA, F., RE, F., MANTOVANI, A., SHANEBECK, K., GRABSTEIN, K.H. and DOWER, S.K., Interleukin 1 signaling occurs exclusively via the type I receptor. Proc. nat. Acad. Sci. (Wash.), 90, 6155-6159 (1993).
57. SMITH, D.R., KUNKEL, S.L., STANDIFORD, T.J., CHENSUE, S.W., ROLFE, M.W., ORRINGER, M.B., WHYTE, R.I., BURDICK, M.D., DANFORTH, J.M., GILBERT, A.R. and STRIETER, R.M., The production of interleukin-1 receptor antagonist by human bronchogenic carcinoma. Amer. J. Pathol., 143, 794-803 (1993).
58. SMITH, E.M., Hormonal activities of cytokines. Chem. Imnnmol., 52, 154-169 (1992).
59. SMITH II, J.W. and 20 OTHERS, The toxic and hematologic effects of interleukin-1 alpha administered in a phase I trial to patients with advanced malignancies. J. clin. Oncol., 10, 1141-1152 (1992).
60. SYMONS, J.A., YOUNG, P.R. and DUFF, G.W., Soluble type II interleukin 1 (IL-1) receptor binds and blocks processing of IL-1β precursor and loses affinity for IL-1 receptor antagonist. Proc. nat. Acad. Sci. (Wash.), 92, 1714-1718 (1995).
61. TADA, M., DISERENS, A.C., DESBAILLETS, I., JAUFEERALLY, R., HAMOU, M.F. and DE TRIBOLET, N., Production of interleukin-1 receptor antagonist by human glioblastoma cells in vitro and in vivo. J. Neuroimmunol., 50, 187-194 (1994).
62. TANAKA, S., NAGASHIMA, T., MANAKA, S., HORI, T. and YASUMOTO, S., Growth suppression and astrocytic differentiation of glioma cells by interleukin-1. J. Neurosurg., 81, 402-410 (1994).
63. THORNBERRY, N.A. and 28 OTHERS. A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes. Nature (Lond.), 356, 768-774 (1992).
64. TOPP, M.S., KOENIGSMANN, M., MIRE-SLUIS, A., OBERBERG, D., ElTELBACH, F., VON MARSCHALL, Z., NOTTER, M., REUFI, B., STEIN, H., THIEL, E. and BERDEL, W.E., Rccombinant human interleukin-4 inhibits growth of some human lung tumor cell lines in vitro and in vivo. Blood, 82, 2837-2844 (1993).
65. TRIOZZI, P.L., KIM, J.A., MARTIN, E.W., YOUNG, D.C., BENZIES, T. and VILLASMIL, P.M., Phase I trial of escalating doses of interleukin-1β in combination with a fixed dose of interleukin-2. J. clin. Oncol., 13, 482-489 (1995).
66. VAN LE, L., HASKILL, S., JAFFE, G.J. and FOWLER, W.C., Expression of interleukin-1 and interlcukin-1 receptor antagonists in endometrial cancer. Gynecol. Oncol., 42, 161-164 (1991).
67. VIDAL-YANACLOCHA, F., AMÉZAGA, C., ASUMENDI, A., KAPLANSKI, G. and DINARELLO, C.A., Interleukin-1 receptor blockade reduces the number and size of murine B16 melanoma hepatic metastases. Cancer Res., 54, 2667-2672 (1994).
68. VON HOFF, D.D., He's not going to talk about in vitro predictive assays again, is he? J. not. Cancer Inst., 82, 96-101 (1990).
69. WILLAMSON, D.J., Specificity of riboprobes for intracellular RNA in hybridization histochemistry. J. Histochem. Cytochem., 36, 811-815(1988).
70. WOODWORTH, C.D., MCMULLIN, E., IGLESIAS, M. and PLOWMAN, G.D., Iriterleukin 1α and tumor necrosis factor α stimulate autocrine amphiregulin expression and proliferation of human papillomuvinis-immortalized and carcinoma-derived cervical epithelial cells. Proc. nat. Acad. Sci. (Wash.), 92, 2840-2844 (1995).
71. YIN, M., GOPAL, V., BANAVALI, S., GARTSIDE, P. and PREISLER, H., Effects of an IL-1 receptor antagonist on acute myeloid leukemia cells. Leukemia, 6, 898-901 (1992).
72. ZEKI, K., NAKANO, Y. INOKUCHI, N., WATANABE, K., MORIMOTO, I., YAMASHITA, U. and ETO, S., Autocrine stimulation of interleukin-1 in the growth of human thyroid carcinoma cell line NIM 1. J. clin. Endocrinol. Metabolism, 76, 127-133 (1993).