Cathepsin D concentration in tumor cytosols improves the accuracy of prognostic evaluation of primary breast cancer

Anticancer Research

Volumn 17, Issue 2B, 1997, Pages 1405-1410

  Ardavanis, A ^a   Scorilas, A ^a   Amanatidou, A ^a   Gerakini, F ^a   Missitzis, I ^a   Garoufali, A ^a   Pissakas, G ^a   Pateras, C ^a   Apostolikas, N ^a   Rigatos, G ^a   Yiotis, I ^a  

^a SAINT SAVVAS HOSPITAL   (Greece)

Author keywords

Breast cancer; Cathepsin D; Prognostic factors

Indexed keywords

CATHEPSIN D;

ARTICLE; BREAST CANCER; CANCER INVASION; CANCER SURGERY; CANCER SURVIVAL; CYTOSOL; FEMALE; FOLLOW UP; HUMAN; HUMAN CELL; HUMAN TISSUE; MAJOR CLINICAL STUDY; PRIORITY JOURNAL; PROGNOSIS; RELAPSE;

EID: 0030996270     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (9)

1. Liotta AL, Stetler-Stevenson WG: Principles of Molecular cell Biology: Cancer Metastasis. In: Cancer. Principles and Practice of Oncology, p 141, V T De Vita, S Helman, SA Rosenberg eds, Lippincott, 1993.
2. Westley B, Rochefort H: A secreted glycoprotein induced by estrogen in human breast cancer cell lines. Cell 20: 353, 1980.
3. Spyratos F, Maudelonde T, Brouillet JP, Brunet M, Defrenne A, Andrieu C, Hacenek K, Desplaces A, Ronesse J, Rochefort H: Cathepsin-D: An independent prognostic factor for metastasis of breast cancer. Lancet 8672 (11): 1115-1118, 1989.
4. Thorpe SM, Rochefort H, Garcia M, Freiss G, Christensen IbJ, Rose C: Association between high concentrations of Mr 52000 cathepsin-D and poor prognosis in primary human breast cancer. Cancer Res 49: 6008-6014, 1989.
5. Tandon A, Clark G, Chamness GC, Chirgwin J, Mc Guire W: Cathepsin-D and prognosis breast cancer. NEJM 322: 297-302, 1990.
6. Scorilas A, Yiotis J, Gouriotis D, Keramopoulos A, Ampela K, Trangas T, Talieri M: Cathepsin-D and c-erb-B 2 have an additive prognostic value for breast cancer patients. Anticancer Res 13: 1895-900, 1993.
7. Spyratos F, Martin PM, Hacene K et al: Multiparametric prognostic evaluation of biological factors in primary breast cancer. J Natl Cancer Inst 84: 1266, 1993.
8. Ravdin PM: Evaluation of of cathepsin D as a prognostic factor in breast cancer. Breast Cancer Res Treat 24: 219, 1993.
9. Janicke F, Schmitt M, Van Putten WLJ et al: Urokinase (uPA) and its inhibitor PAI-1 are strong and independent prognostic factors in node-negative breast cancer. Breast Cancer Res Treat 24: 195, 1993.